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Author : Warren C. Hyer
Publisher : ASTM International
ISBN 13 : 0803112645
Total Pages : 167 pages
Book Rating : 4.8/5 (31 download)
Download or read book Bioprocessing Safety written by Warren C. Hyer and published by ASTM International. This book was released on 1990 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : P. Hambleton
Publisher : Springer Science & Business Media
ISBN 13 : 9401113521
Total Pages : 317 pages
Book Rating : 4.4/5 (11 download)
Download or read book Biosafety in Industrial Biotechnology written by P. Hambleton and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: As an industry, biotechnology may be likened to the Hymn Book, being both ancient and modern. Whereas activities such as baking, brewing, the fermenting of foods date from our earliest attempts to control and utilise the environment, the application of recombinant DNA technology is recognised as being at the forefront of novel industrial development. Perhaps because of its association with processing foodstuffs together with the benefits derived from applications in the early organic chemistry and pharmaceutical industries, biotechnology has been regarded as being inherently safe. Yet unlike other modern industries, such as chemical and nuclear, where regulation has followed from incidents or accidents, modern biotechnology has been subject to close scrutiny and regulation almost from its inception. The process of regulation itself is somewhat unusual in that it was initially self-imposed by the very scientists who developed the fundamental techniques of recombinant DNA technology. They recognised the signific ance of their development but were concerned of the effects on humans and the environment of uncontrolled application of the new, powerful technology. Concern about the possible consequences of genetic manipula tion has undoubtedly been the driving force behind the regulations that are now in place in many parts of the world and which are the subject of this book. Safety issues in the biotechnology industry can be categorised under three headings: worker, environmental and consumer (product) safety.
Author :
Publisher :
ISBN 13 :
Total Pages : 1076 pages
Book Rating : 4.3/5 (91 download)
Download or read book Environmental Pollution & Control written by and published by . This book was released on 1990 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : G. Stacey
Publisher : Springer Science & Business Media
ISBN 13 : 940114916X
Total Pages : 257 pages
Book Rating : 4.4/5 (11 download)
Download or read book Safety in Cell and Tissue Culture written by G. Stacey and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now more than half a century since animal cells first came into regular use in the laboratory. Instances of laboratory acquired infection and con tamination of therapeutic products, derived from the use of animal cell cultures are rare. The use of animal cells, in addition to an established role in the production of vaccines and therapeutic proteins, has many new medical applications including gene therapy, tissue engineering and cell therapy. Furthermore, C;ldvances in molecular and cell biology are enabling rapid development and application of these technologies and the development of new and more sensitive methods, such as nucleic acid amplification, for the characterisation of cells and the detection of adven titious agents. However, it is clear that there is no room for complacency in this field and the recent expansion in the use of animal cells in the manufacture of medical products and the development of new biological assays for diagnostic and pharmaco-toxicological screening, underlines the need for vigilance regarding the correct and safe use of animal cells as substrates. This book is therefore very timely and should prove to be a highly valuable text, finding a wider audience beyond those with respon sibility for laboratory safety. The book guides the reader from fundamental cell biology issues and the establishment of new in vitro methods, through testing and validation of cell lines and on to issues in the use of animal cells in manufacturing processes.
Author :
Publisher :
ISBN 13 :
Total Pages : 1002 pages
Book Rating : 4.3/5 (91 download)
Download or read book Government Reports Announcements & Index written by and published by . This book was released on 1990 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309047854
Total Pages : 133 pages
Book Rating : 4.3/5 (9 download)
Download or read book Putting Biotechnology to Work written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309316553
Total Pages : 158 pages
Book Rating : 4.3/5 (93 download)
Download or read book Industrialization of Biology written by National Research Council and published by National Academies Press. This book was released on 2015-06-29 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tremendous progress in biology over the last half century - from Watson and Crick's elucidation of the structure of DNA to today's astonishing, rapid progress in the field of synthetic biology - has positioned us for significant innovation in chemical production. New bio-based chemicals, improved public health through improved drugs and diagnostics, and biofuels that reduce our dependency on oil are all results of research and innovation in the biological sciences. In the past decade, we have witnessed major advances made possible by biotechnology in areas such as rapid, low-cost DNA sequencing, metabolic engineering, and high-throughput screening. The manufacturing of chemicals using biological synthesis and engineering could expand even faster. A proactive strategy - implemented through the development of a technical roadmap similar to those that enabled sustained growth in the semiconductor industry and our explorations of space - is needed if we are to realize the widespread benefits of accelerating the industrialization of biology. Industrialization of Biology presents such a roadmap to achieve key technical milestones for chemical manufacturing through biological routes. This report examines the technical, economic, and societal factors that limit the adoption of bioprocessing in the chemical industry today and which, if surmounted, would markedly accelerate the advanced manufacturing of chemicals via industrial biotechnology. Working at the interface of synthetic chemistry, metabolic engineering, molecular biology, and synthetic biology, Industrialization of Biology identifies key technical goals for next-generation chemical manufacturing, then identifies the gaps in knowledge, tools, techniques, and systems required to meet those goals, and targets and timelines for achieving them. This report also considers the skills necessary to accomplish the roadmap goals, and what training opportunities are required to produce the cadre of skilled scientists and engineers needed.
Author : Ajay Kumar
Publisher : CRC Press
ISBN 13 : 104015400X
Total Pages : 391 pages
Book Rating : 4.0/5 (41 download)
Download or read book Advances in Sustainable Biomaterials written by Ajay Kumar and published by CRC Press. This book was released on 2024-10-28 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sustainable biomaterials are used as substitutions for traditional materials in aerospace, automotive, civil, mechanical, environmental engineering, medical, and other industries. This book presents the current knowledge and recent developments on the characterization and application of sustainable biomaterials with biomanufacturing 4.0 techniques. The book also describes the unique properties of various classes of sustainable biomaterials, making them highly suitable for many industrial applications. Advances in Sustainable Biomaterials: Bioprocessing 4.0, Characterizations, and Applications presents key chapters on smart biopolymer composites production and processing methods and provides a wide range of applications in a variety of fields such as medical, food, agriculture, electronics, manufacturing, and chemical engineering. The book features the most recent and detailed information on advancements in biopolymer biomaterials and emphasizes synthesis, characterization, modeling, manufacturing, and testing strategies. Written to be used as a resource guide on biomaterials and innovations, undergraduate and postgraduate students studying manufacturing and materials science will find this book very useful in addition to those working in mechanical engineering, biomedical engineering, manufacturing of pharmaceuticals, biotechnology, and electronics engineering fields. The book can also be used as additional classroom reading for an advanced course on biomaterials modeling and optimization.
Author : Amine Kamen
Publisher : CRC Press
ISBN 13 : 1000643050
Total Pages : 267 pages
Book Rating : 4.0/5 (6 download)
Download or read book Bioprocessing of Viral Vaccines written by Amine Kamen and published by CRC Press. This book was released on 2022-09-06 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309452058
Total Pages : 231 pages
Book Rating : 4.3/5 (94 download)
Download or read book Preparing for Future Products of Biotechnology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-07-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.
Author : Pau Loke Show
Publisher : CRC Press
ISBN 13 : 1000407411
Total Pages : 327 pages
Book Rating : 4.0/5 (4 download)
Download or read book The Prospect of Industry 5.0 in Biomanufacturing written by Pau Loke Show and published by CRC Press. This book was released on 2021-07-01 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to present the idea of Industry 5.0 in biomanufacturing and bioprocess engineering, both upstream and downstream. The Prospect of Industry 5.0 in Biomanufacturing details the latest technologies and how they can be used efficiently and explains process analysis from an engineering point of view. In addition, it covers applications and challenges. FEATURES Describes the previous Industrial Revolution, current Industry 4.0, and how new technologies will transition toward Industry 5.0 Explains how Industry 5.0 can be applied in biomanufacturing Demonstrates new technologies catered to Industry 5.0 Uses worked examples related to biological systems This book enables readers in industry and academia working in the biomanufacturing engineering sector to understand current trends and future directions in this field.
Author : Regine Eibl
Publisher : John Wiley & Sons
ISBN 13 : 1119477786
Total Pages : 367 pages
Book Rating : 4.1/5 (194 download)
Download or read book Single-Use Technology in Biopharmaceutical Manufacture written by Regine Eibl and published by John Wiley & Sons. This book was released on 2019-07-18 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authoritative guide to the principles, characteristics, engineering aspects, economics, and applications of disposables in the manufacture of biopharmaceuticals The revised and updated second edition of Single-Use Technology in Biopharmaceutical Manufacture offers a comprehensive examination of the most-commonly used disposables in the manufacture of biopharmaceuticals. The authors—noted experts on the topic—provide the essential information on the principles, characteristics, engineering aspects, economics, and applications. This authoritative guide contains the basic knowledge and information about disposable equipment. The author also discusses biopharmaceuticals’ applications through the lens of case studies that clearly illustrate the role of manufacturing, quality assurance, and environmental influences. This updated second edition revises existing information with recent developments that have taken place since the first edition was published. The book also presents the latest advances in the field of single-use technology and explores topics including applying single-use devices for microorganisms, human mesenchymal stem cells, and T-cells. This important book: • Contains an updated and end-to-end view of the development and manufacturing of single-use biologics • Helps in the identification of appropriate disposables and relevant vendors • Offers illustrative case studies that examine manufacturing, quality assurance, and environmental influences • Includes updated coverage on cross-functional/transversal dependencies, significant improvements made by suppliers, and the successful application of the single-use technologies Written for biopharmaceutical manufacturers, process developers, and biological and chemical engineers, Single-Use Technology in Biopharmaceutical Manufacture, 2nd Edition provides the information needed for professionals to come to an easier decision for or against disposable alternatives and to choose the appropriate system.
Author : Megh R. Goyal
Publisher : CRC Press
ISBN 13 : 1000564991
Total Pages : 308 pages
Book Rating : 4.0/5 (5 download)
Download or read book Nanotechnology Applications in Agricultural and Bioprocess Engineering written by Megh R. Goyal and published by CRC Press. This book was released on 2022-06-16 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume looks at new research and advances in the use of nanotechnology applications in agricultural and bioprocess engineering. The first section deals with the impact of nanotechnology in agricultural engineering, looking at the role of nanomaterials in plant growth and nutrition. It goes on to discuss specific methods and processes in the development of food products, nutraceuticals, and therapeutics. This includes nanotechnological methods for iron fortification of dairy food, for processing and preservation of meat and meat products, for selective targeting of cancer, and more. The book then discusses the role of nanotechnology in bioprocessing, such as for biofuel production, for wastewater treatment, and as enzymatic nanoparticles for fabrication processes.
Author : Junaid Ahmad Malik
Publisher : Elsevier
ISBN 13 : 032390453X
Total Pages : 922 pages
Book Rating : 4.3/5 (239 download)
Download or read book Microbes and Microbial Biotechnology for Green Remediation written by Junaid Ahmad Malik and published by Elsevier. This book was released on 2022-06-14 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbes and Microbial Biotechnology for Green Remediation provides a comprehensive account of sustainable microbial treatment technologies. The research presented highlights the significantly important microbial species involved in remediation, the mechanisms of remediation by various microbes, and suggestions for future improvement of bioremediation technology. The introduction of contaminants, due to rapid urbanization and anthropogenic activities, into the environment causes unsteadiness and distress to the physicochemical systems, including living organisms. Hence, there is an immediate global demand for the diminution of such contaminants and xenobiotics which can otherwise adversely affect the living organisms. Over time, microbial remediation processes have been accelerated to produce better, eco-friendlier, and more biodegradable products for complete dissemination of these xenobiotic compounds. The advancements in microbiology and biotechnology lead to the launch of microbial biotechnology as a separate area of research and contributed dramatically to the development of the areas such as agriculture, environment, biopharmaceutics, and fermented foods. Microbes stand as an imperative, efficient, green, and economical alternative to conventional treatment technologies. The proposed book provides cost-effective and sustainable alternatives. This book serves as a reference for graduate and postgraduate students in environmental biotechnology and microbiology as well as researchers and scientists working in the laboratories and industries involved in research related to microbiology, environmental biotechnology, and allied research. - Discusses important microbial activities, such as biofertilizer, biocontrol, biosorption, biochar, biofilm, biodegradation, bioremediation, bioclogging, and quorum sensing - Covers all the advanced microbial bioremediation techniques which are finding their way from the laboratory to the field for revival of the degraded agro-ecosystems - Examines the role of bacteria, fungi, microalgae, Bacillus sp., Prosopis juliflora, Deinococcus radiodurans, Pseudomonas, methanotrophs, siderophores, and PGPRs as the biocontrol and green remediator agents for soil sustainability
Author : Ganapathy Subramanian
Publisher : John Wiley & Sons
ISBN 13 : 3527340637
Total Pages : 628 pages
Book Rating : 4.5/5 (273 download)
Download or read book Continuous Biomanufacturing written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2017-12-26 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.
Author : Pauline M. Doran
Publisher : Elsevier
ISBN 13 : 0080528120
Total Pages : 455 pages
Book Rating : 4.0/5 (85 download)
Download or read book Bioprocess Engineering Principles written by Pauline M. Doran and published by Elsevier. This book was released on 1995-04-03 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.
Author : United States. Congress. Office of Technology Assessment
Publisher : Office of Technology Assessment
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 (319 download)
Download or read book Biotechnology in a Global Economy written by United States. Congress. Office of Technology Assessment and published by Office of Technology Assessment. This book was released on 1991 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comercial activity; Industrial policy; International competitiveness; Options for action by congress.
