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Personalized Medicine And Neurosurgery
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Book Synopsis Personalized Medicine and Neurosurgery by :
Download or read book Personalized Medicine and Neurosurgery written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related "-omic" approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.
Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain
Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2009-08-29 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic. There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author’s efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.
Book Synopsis Personalized Medicine and Neurosurgery by : M. Yashar S. Kalani
Download or read book Personalized Medicine and Neurosurgery written by M. Yashar S. Kalani and published by Frontiers Media SA. This book was released on 2017-11-22 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have made to science and medicine, and it set the stage for their federally funded and mandated integration into the delivery of health care. Whether these advances comprise large-scale approaches, such as The Cancer Genome Atlas, which provides a modern classification of cancers based on molecular profiles, or genealogy initiatives, which seek to trace the movement of our early ancestors out of Africa, genomic technology has taken us closer to developing targeted therapies and a refined understanding of our evolutionary journey. It is against this backdrop that we summarized some of the recent advances in the field of precision medicine, or personalized medicine, as they pertain to neurosurgery. In this e-Book collection provided by Frontiers in Surgery: Neurosurgery, we present a collection of articles by leaders in the field of neurosurgery that highlight domains using a personalized approach for the treatment of patients or avenues when personalization is possible and when it will likely alter the care of patients with neurological diseases.
Book Synopsis Evidence based practice in Neuro-oncology by : Supriya Mallick
Download or read book Evidence based practice in Neuro-oncology written by Supriya Mallick and published by Springer Nature. This book was released on 2021-07-24 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides evidence-based management in neuro-oncology covering all aspects such as pathology, radiology, surgery, radiation, and chemotherapy.The field of neuro-oncology is rapidly evolving and new evidence is coming out every day towards the optimal management of brain tumors. This necessitates a requirement of a complete guide that shall provide an evidence-based and personalized approach towards dealing with patients. This book also covers recent advances in personalized treatment formed through the relevant basis of anatomy, imaging, radiology, surgical, radiation and systemic treatment of brain and spinal tumors. In addition it also covers the , practical aspects of the planning of the Gamma knife and other radio surgical aspects. The book shall provide valuable assistance to practicing neuro-oncologists to practice better evidence-based personalized medicine.
Book Synopsis Ethics of Innovation in Neurosurgery by : Marike L. D. Broekman
Download or read book Ethics of Innovation in Neurosurgery written by Marike L. D. Broekman and published by Springer. This book was released on 2019-02-21 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all ethical aspects of introducing novel implants and procedures in neurosurgery in a structured way, addressing the current knowledge gap concerning ethical innovations in neurosurgery. Initially it explores the difficulties involved in defining when a procedure should be considered innovation, research, or care. To this end, it presents not only an overview of current literature, but also data from a recent survey among neurosurgeons in Europe. The book subsequently discusses the ethical issues related to innovation. These include: informed consent (what should a surgeon tell the patient and how should he/she do so), oversight (can any surgeon simply implant a novel spinal device?), the learning curve (when should a surgeon be allowed to perform a novel procedure?), vulnerable patients (how to innovate in the pediatric population or in an emergency setting), and conflicts of interest, as well as the ethics of paying for innovative treatments. In turn, the closing chapters focus on the evaluation of neurosurgical research and innovation. Are cultural changes necessary and how could innovation benefit from (international) collaborations? Given the range of topics addressed, the book offers neurosurgeons, residents, scientists, companies and hospital administrations a valuable guide to introducing novel implants and techniques in neurosurgery.
Book Synopsis Surviving Neurosurgery by : Nitin Agarwal
Download or read book Surviving Neurosurgery written by Nitin Agarwal and published by Springer. This book was released on 2022-01-26 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surviving Neurosurgery: Vignettes of Resilience is a practical guide to the inner workings of the lives of neurosurgeons, healthcare partners, and patients. To this end, this text serves as a first-hand documentary of the unique challenges faced as one progresses through their career. It is a snapshot in time capturing the experiences of both patients and providers. The text is divided into seven parts that run the gamut of a neurosurgeon’s career symbolic of the seven years of neurosurgical training. These narratives include, but are not limited to, residency challenges, surgical nuances, research and funding, embracing humanity, patient experiences, and overcoming hurdles along the journey. Chapters share the wisdom and experiences of over 100 authors consisting of patients, trainees, advanced practice providers, and attending neurosurgeons.
Book Synopsis Fifty Years of Neurosurgery by : Ernest Sachs
Download or read book Fifty Years of Neurosurgery written by Ernest Sachs and published by . This book was released on 1958 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The New Era of Precision Medicine by : Mohamad Bydon
Download or read book The New Era of Precision Medicine written by Mohamad Bydon and published by Elsevier. This book was released on 2023-11-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New Era of Precision Medicine: What it Means for Patients and the Future of Healthcare highlights aspects of precision medicine in different specialties and offers an understanding of how a biological background integrates into clinical guidelines, the therapeutic efficacy of interventions and disease prevention. The book explains how precision healthcare differs among countries, as well as how there is a collaboration among many labs to share resources and knowledge to advance the field across the globe. The book also discusses the cultural differences and cultural sensitivity that may be involved in the precision medicine approach. Finally, with regard to safety and quality outcomes, the book presents a range of current and possible future concerns related to those outcomes. Precision medicine is the new standard of quality healthcare delivery. It aims to optimize patient safety and clinical outcomes, enhance the efficacy of therapeutic interventions, and facilitate disease prevention, offering a way to customize patient care, decision-making, and clinical practice. Highlights the characteristics of precision medicine in different areas Offers an understanding of how a biological background integrates into clinical guidelines, the therapeutic efficacy of interventions, and disease prevention Emphasizes how medicine has transformed from a “one-size-fits-all approach to personalized medicine influenced by individual characteristics Introduces complex topics delivered in terms that target a broad range of audiences
Book Synopsis Becoming Dr. Q by : Alfredo Quiñones-Hinojosa
Download or read book Becoming Dr. Q written by Alfredo Quiñones-Hinojosa and published by Univ of California Press. This book was released on 2011-10-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today he is known as Dr. Q, an internationally renowned neurosurgeon and neuroscientist who leads cutting-edge research to cure brain cancer. But not too long ago, he was Freddy, a nineteen-year-old undocumented migrant worker toiling in the tomato fields of central California. In this gripping memoir, Alfredo Quiñones-Hinojosa tells his amazing life story—from his impoverished childhood in the tiny village of Palaco, Mexico, to his harrowing border crossing and his transformation from illegal immigrant to American citizen and gifted student at the University of California at Berkeley and at Harvard Medical School. Packed with adventure and adversity—including a few terrifying brushes with death—Becoming Dr. Q is a testament to persistence, hard work, the power of hope and imagination, and the pursuit of excellence. It’s also a story about the importance of family, of mentors, and of giving people a chance.
Download or read book A Life in Neurosurgery written by Elwood and published by . This book was released on 2019-02-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Precision Medicine in Neurodegenerative Disorders by :
Download or read book Precision Medicine in Neurodegenerative Disorders written by and published by Elsevier. This book was released on 2023-02-14 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-splitting tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine. Summarizes theory and research on precision medicine in neurodegenerative disorders Covers basic biology, clinical trials and therapeutics Includes disease mechanisms, genetic subtypes, and more
Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain
Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.
Book Synopsis A History of Neurosurgery by : Samuel H. Greenblatt
Download or read book A History of Neurosurgery written by Samuel H. Greenblatt and published by Thieme. This book was released on 1997 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: A History of Neurosurgery is the first thorough book on the history of neurosurgery published since 1951. The book is organized around a specific historiographic framework that traces the advancement of the specialty. Included are chapters on ancient trepanation, Macewen's first use of the combined technologies of anesthesia, antisepsis and cortical localization in 1879 to plan and perform craniotomies, the emergence of Harvey Cushing's leadership, the evolution of modern neurosurgical techniques and technology and much more.
Author :Christianto B. Lumenta Publisher :Springer Science & Business Media ISBN 13 :3540795650 Total Pages :651 pages Book Rating :4.5/5 (47 download)
Book Synopsis Neurosurgery by : Christianto B. Lumenta
Download or read book Neurosurgery written by Christianto B. Lumenta and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a specialized field such as neurosurgery, highly specific knowledge is required. Training programs in the EU vary, making it difficult to standardize medical training. This manual forms the basis for a European consensus in neurosurgery. It is written for residents, students and physicians with a special interest in neurosurgery. Diagnostic and therapeutic procedures are detailed according to localization (cranial, spinal, peripheral nerves) with special consideration given to congenital defects and pediatric neurosurgical disorders, functional and stereotactic neurosurgery, as well as critical neurosurgical care. Each chapter contains the basics of anatomy and physiology. The book is well-organized and clearly structured according to each entity and its neurosurgical treatment options. A better understanding of specific neurosurgical problems will help practicing neurosurgeons provide better medical care for their patients, and will also provide the neurosurgery resident with a reliable European standard for step-by-step management of neurosurgical problems, which will prove useful when preparing for the board examination.
Book Synopsis Connectomic Deep Brain Stimulation by : Andreas Horn
Download or read book Connectomic Deep Brain Stimulation written by Andreas Horn and published by Academic Press. This book was released on 2021-09-10 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) Presents references (key articles, books and protocols) for additional detailed study Provides data analysis boxes in each chapter to help with data interpretation
Book Synopsis Toward Precision Medicine by : National Research Council
Download or read book Toward Precision Medicine written by National Research Council and published by National Academies Press. This book was released on 2012-01-16 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.
Book Synopsis Practical Handbook of Neurosurgery by : Marc Sindou
Download or read book Practical Handbook of Neurosurgery written by Marc Sindou and published by Springer. This book was released on 2009-06-29 with total page 1712 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Practical Handbook of Neurosurgery” invites readers to take part in a journey through the vast field of neurosurgery, in the company of internationally renowned experts. At a time when the discipline is experiencing a (detrimental) tendency to segment into various subfields and scatter in the process, it can be worthwhile to collect a number of practical lessons gleaned from experienced and leading neurosurgeons. The book also aims to present numerous important figures in the neurosurgical community, with a brief overview of the vitae and main contributions for each. We must confess that we were sad that some of the most active members were unable to participate, likely due to time constraints. We are however fortunate that the majority were able to take part. As such, though not exhaustive, the book does represent an anthology of contemporary neurosurgeons. From the preface: At the very beginning of the project, our intention was to make a “poetbook”. But month after month it became obvious that the work would be much more expansive; ultimately we produced three volumes. Nevertheless we hope that all the three volumes together will remain easily accessible and a daily companion. The pocket has to be more like a travel bag! We would like to thank all of the contributors; they have sacrficed their valuable time to deliver sound and critical views, and above all useful guidelines.
