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Author : Harold Gainer
Publisher : Springer Science & Business Media
ISBN 13 : 1461341302
Total Pages : 478 pages
Book Rating : 4.4/5 (613 download)
Download or read book Peptides in Neurobiology written by Harold Gainer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Lee E. Eiden
Publisher : Frontiers Media SA
ISBN 13 : 2889632253
Total Pages : 203 pages
Book Rating : 4.8/5 (896 download)
Download or read book Regulatory Peptides in Neuroscience and Endocrinology: A New Era Begins written by Lee E. Eiden and published by Frontiers Media SA. This book was released on 2019 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic features recent developments in the field of regulatory peptide physiology and peptide-based therapeutics.
Author : Simo S. Oja
Publisher : Springer Nature
ISBN 13 : 0387303731
Total Pages : 418 pages
Book Rating : 4.3/5 (873 download)
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Simo S. Oja and published by Springer Nature. This book was released on 2010-07-29 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ramon Lim
Publisher : Springer Science & Business Media
ISBN 13 : 0387303480
Total Pages : 691 pages
Book Rating : 4.3/5 (873 download)
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Ramon Lim and published by Springer Science & Business Media. This book was released on 2006-09-18 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.
Author : William F. Colmers
Publisher : Springer Science & Business Media
ISBN 13 : 1592594654
Total Pages : 577 pages
Book Rating : 4.5/5 (925 download)
Download or read book The Biology of Neuropeptide Y and Related Peptides written by William F. Colmers and published by Springer Science & Business Media. This book was released on 1993-03-24 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts critically summarize the state of knowledge concerning the molecular, anatomical, physiological, and behavioral aspects of NPY and its congeners. Each article provides a comprehensive and in-depth survey, an overview of the role of NPY in the discipline covered, a discussion of the likely future direction that the field will take, and an up-to-date bibliography. Chapters include a treatment of the evolution of the PP family of genes, the structure of the NPY gene, and the distribution of NPY on the cardiovascular system, actions of NPY on the electrophysiological properties of nerve cells, and the effects of NPY on feeding and behavior. The chapters are written in an accessible style and serve both as an introduction to the field and as an extensive and detailed treatment of the current state of knowledge.
Author : Zofia Zukowska
Publisher : Springer Science & Business Media
ISBN 13 : 3764374179
Total Pages : 276 pages
Book Rating : 4.7/5 (643 download)
Download or read book NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics written by Zofia Zukowska and published by Springer Science & Business Media. This book was released on 2006-03-28 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. The recognition of the role of NPY in stimulation of food intake has already resulted in discovery of potent and selective NPY receptor Y-5 antagonists which are in clinical development for obesity while NPY Y1 receptors are targeted for cardiovascular indications. Research into the multiple functions of NPY and its receptors in neurological and affective disorders are also actively pursued. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabolic disorders, written by internationally renowned experts with the objective to synthesize leading concepts and data in support for translational medicine.
Author : Jeffery L. Barker
Publisher :
ISBN 13 :
Total Pages : 792 pages
Book Rating : 4.:/5 (45 download)
Download or read book The Role of Peptides in Neuronal Function written by Jeffery L. Barker and published by . This book was released on 1980 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dorothy T. Krieger
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 1054 pages
Book Rating : 4.3/5 (91 download)
Download or read book Brain Peptides written by Dorothy T. Krieger and published by Wiley-Interscience. This book was released on 1983-11-14 with total page 1054 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first major comprehensive overview of the anatomical, physiological, evolutionary, and embryological aspects of brain peptides, focusing on peptides described in the past decade. Examines the role of peptides in affecting major homeostatic systems. Presents the methodologies applicable to the study of brain peptides. Summarizes current knowledge of individual peptides.
Author : James A. Ferrendelli
Publisher : Springer Science & Business Media
ISBN 13 : 1461317215
Total Pages : 285 pages
Book Rating : 4.4/5 (613 download)
Download or read book Neurobiology of Amino Acids, Peptides and Trophic Factors written by James A. Ferrendelli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of the third in a series of annual inter national symposia. The first, The Neuroregulation of Autonomic, Endocrine, and Immune Systems, was held in Indianapolis in the fall of 1985. The second, Psychological and Biological Approaches to the Understanding of Human Disease, was held in Bielefeld, Germany in the fall of 1986. The theme of this series concerns the communication between the central nervous system and the other major systems of the body, and the purpose is to monitor the frontiers of research into these neuronal/hormonal regulatory interactions and their application to medicine. The present volume deals with the role of peptides and amino acids in these information transfer processes. Great strides have been made in exploring the important role of amino acids and pep tides in neuroregulation, and the ongoing biotechnology revolution promises signi ficant scientific and medical advances throughout the next decade and beyond. The work described in this volume captures the great excitement and pro mise of this biomedical renaissance. This meeting was cosponsored by Searle/ Monsanto and Washington University and held in St. Louis in the early fall of 1986. A major contributor to these proceedings was Dr. Thomas O'Donohue whose chapter deals with his work in characterizing the endogenous ligands for the PCP and sigma opioid receptors. Tom's personality and career personi fied the dedication of this series to the principle of a broad multidisciplinary approach to scientific problems.
Author : M. Segal
Publisher : Springer Science & Business Media
ISBN 13 : 9400922299
Total Pages : 202 pages
Book Rating : 4.4/5 (9 download)
Download or read book The Blood-Brain Barrier, Amino Acids and Peptides written by M. Segal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Definition of the barrier The interstitial fluid (rSF) of the brain is separated from the blood by the blood-brain barrier (BBB). This barrier must not be thought of as a single entity or as an absolute restriction to all molecules, but as a multiple structure located at several sites within the brain. The first of these interfaces is located at the endothelium of the brain capillaries. Secondly there is a potential site for interchange on the outer linings of the brain between the dura and the arachnoid membranes. Thirdly, there are the choroid plexuses and the cerebrospinal fluid (CSF) which is in contact with the very permeable internal ependymal lining of the brain (Figure 1. 1). Finally there are areas of the brain which lack a blood-brain barrier. These areas constitute the circumventricu lar organs and have leaky capillaries with a barrier at the ependyma which limits the spread of molecules from those regions (Figure 1. 2). Each of these BBB sites has its own characteristic permeability and transport functions. We will now consider the properties of each of these barrier sites between the blood and the brain. THE CEREBRAL CAPILLARY ENDOTHELIUM Morphology This interface has both the largest surface area and the shortest path length between the blood and the brain rSF. The cerebral capillaries, which at first sight seem little different from the rest of the systemic circulation, are in fact unique to the brain.
Author : Gerard O'Cuinn
Publisher : CRC Press
ISBN 13 : 1000714764
Total Pages : 272 pages
Book Rating : 4.0/5 (7 download)
Download or read book Metabolism of Brain Peptides written by Gerard O'Cuinn and published by CRC Press. This book was released on 2020-02-03 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolism of Brain Peptides discusses neuropeptide metabolism in light of recent research. It describes the processing mechanisms in the production of biologically active peptides. It details distribution of the variety of neuropeptides in the brain and comprehensively reviews the effects of these neuropeptides on behavioral and physiological functions. The book also examines termination mechanisms for the biological activities of neuropeptides in light of recent knowledge of their distribution, their receptors and their possible inactivation enzymes in various functional regions of the brain and at the blood-brain barrier.
Author :
Publisher : Elsevier
ISBN 13 : 0080861911
Total Pages : 393 pages
Book Rating : 4.0/5 (88 download)
Download or read book Peptides and Neurological Disease written by and published by Elsevier. This book was released on 1986-01-01 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and Neurological Disease
Author : Antonio M. Gotto
Publisher : North-Holland
ISBN 13 :
Total Pages : 426 pages
Book Rating : 4.3/5 (91 download)
Download or read book Brain Peptides written by Antonio M. Gotto and published by North-Holland. This book was released on 1979 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurobiology of Peptides written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth W. McKerns
Publisher : Springer Science & Business Media
ISBN 13 : 1461592488
Total Pages : 642 pages
Book Rating : 4.4/5 (615 download)
Download or read book Hormonally Active Brain Peptides written by Kenneth W. McKerns and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Near the end of September 1980, the contributors to Hormonally Active Brain Pep tides: Structure and Function met to discuss their chapters for the monograph. This meeting was the eighth sponsored by the International Foundation for Biochemical Endocrinology and was held at the Hotel Plakir in Dubrovnik, Yugoslavia. Several months were allowed after the meeting for the contributors to revise their manuscripts and for editing. Professor Dr. Vladimir Pantie and the Serbian Academy of Sciences and Arts were in charge of the local arrangements and social activities. The Foundation is grateful for the splendid job that was done and for the out standing scientific, cultural, and social activities. I thank the Serbian Acad emy of Sciences and Arts and the Yugoslav Council of Academies for spon soring my stay in Yugoslavia. I greatly enjoyed giving lectures, visiting laboratories, and discussing research projects in a number of centers in Yugoslavia. A diverse group of topics was presented in Dubrovnik concerning cer tain brain peptides. The topics included "Structure, Function, and Confor mation of Neuropeptides," "Distribution of Peptides in the Brain," "Reg ulation of the Release of Peptide Hormones," "The Active Center of Gonadotropins," "In Vitro Synthesis of Hypothalamic Hormones," "Stud ies on Gonadotropin-Releasing Hormone," "Studies on the Biosynthesis, Release, and Degradation of LH-RH," "Genesis and Properties of Pitu itary ACTH, Prolactin, and Growth Hormone Producing Cells," "Precur sors to Oligopeptide Hormones," and "Stress Effects on Peptide Hormone Synthesis
Author : Laszlo Prokai
Publisher : Birkhäuser
ISBN 13 : 3034880499
Total Pages : 250 pages
Book Rating : 4.0/5 (348 download)
Download or read book Peptide Transport and Delivery into the Central Nervous System written by Laszlo Prokai and published by Birkhäuser. This book was released on 2012-12-06 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypo- or hypersecretion, alteration in storage, release, catabolism, and post-translational processing of neuropeptides are associated with the etiology of many diseases affecting the central nervous system (CNS). Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics developed as their agonists or antagonists could be useful in the treatment of these CNS maladies. However, peptides face a formidable obstacle in reaching the intended site of action due to the existence of the blood-brain barrier (BBB), a vital element in the regulation of the internal environment of the brain and the spinal cord. After reviews on the role and neuropharmaceutical potential of peptides, properties of the BBB in the context of peptide transport in the CNS and potential transport mechanisms to cross the BBB, this volume discusses the development, present state-of-the-art and future trends of various strategies to overcome this major obstacle to peptide pharmacotherapy involving the CNS. Chapters are devoted to cover invasive approaches that circumvent the BBB by direct administration into the brain or the spinal cord and by transiently opening the tight junctions of or permeabilizing the endothelial cells separating the systemic circulation from the interstitial fluid of the CNS. Subsequently, physiologically based strategies that utilize biological carriers to gain access to the CNS are discussed in detail, followed by methods encompassing prodrug and chemical delivery/targeting strategies, which aim at altering the properties of the peptide to enhance BBB transport, and drug delivery strategies based on peptide vectors. Finally, a comparative evaluation on the present status and perspectives of the techniques is presented.
Author : Erminio Costa
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 688 pages
Book Rating : 4.:/5 (318 download)
Download or read book Neural Peptides and Neuronal Communication written by Erminio Costa and published by Raven Press (ID). This book was released on 1980 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:
