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Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies

Author : OECD
Publisher : OECD Publishing
ISBN 13 : 9264805907
Total Pages : 447 pages
Book Rating : 4.2/5 (648 download)

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Book Synopsis Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies by : OECD

Download or read book Improving Healthcare Quality in Europe Characteristics, Effectiveness and Implementation of Different Strategies written by OECD and published by OECD Publishing. This book was released on 2019-10-17 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, developed by the Observatory together with OECD, provides an overall conceptual framework for understanding and applying strategies aimed at improving quality of care. Crucially, it summarizes available evidence on different quality strategies and provides recommendations for their implementation. This book is intended to help policy-makers to understand concepts of quality and to support them to evaluate single strategies and combinations of strategies.

The Metabolic Pathway Engineering Handbook

Author : Christina Smolke
Publisher : CRC Press
ISBN 13 : 1439802971
Total Pages : 680 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Metabolic Pathway Engineering Handbook by : Christina Smolke

Download or read book The Metabolic Pathway Engineering Handbook written by Christina Smolke and published by CRC Press. This book was released on 2009-07-28 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first volume of the Metabolic Pathway Engineering Handbook provides an overview of metabolic pathway engineering with a look towards the future. It discusses cellular metabolism, including transport processes inside the cell and energy generating reactions, as well as rare metabolic conversions. This volume also explores balances and reaction

Finding Pathways

Author : Nicholas Weller
Publisher : Cambridge University Press
ISBN 13 : 1107041066
Total Pages : 173 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Finding Pathways by : Nicholas Weller

Download or read book Finding Pathways written by Nicholas Weller and published by Cambridge University Press. This book was released on 2014-07-03 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces 'pathway analysis', a method to combine large and small-N research techniques and to aid understanding of causal mechanisms.

The Shikimic Acid Pathway

Author : Eric E. Conn
Publisher : Springer Science & Business Media
ISBN 13 : 1468480561
Total Pages : 348 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Shikimic Acid Pathway by : Eric E. Conn

Download or read book The Shikimic Acid Pathway written by Eric E. Conn and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the invited papers presented as a symposium of The Phytochemical Society of North America which met for its annual meeting at the Asilomar Conference Center, Pacific Grove, California on June 12-16, 1985. The topic of the symposium, "The Shikimic Acid Pathway - Recent Advances", was especially appropriate for this, the Silver Anniversary of the Society because of the many natural products derived from that pathway. The organizers of the symposium recognized that it would not be possible to cover all groups of compounds derived from shikimic acid and therefore decided to omit any detailed discussion of flavonoid compounds and lignin. Research in these two areas has been the subject of several recent symposiums and/or published volumes. By omitting these topics, it was possible to devote more attention to other, equally interesting products derived from the shikimate pathway. Each chapter in the volume authoritat~vely speaks for itself on an important topic. However, the reader is invited to enjoy the lead chapter by Ulrich Weiss who describes his role in the research on the shikimate pathway during 1952/53. We are grateful to Dr. Weiss for this charming account of his work carried out in the laboratory of Dr. B. D. Davis during that period. Those who attended the Silver Anniversary Meeting were privileged to hear Dr. Gestur Johnson reminisce about the founding of the Society, initially called the Plant Phenolics Group of North America. At the annual banquet R. Horwitz also shared with us some recollections of Dr.

The Pentose Phosphate Pathway

Author : Terry Wood
Publisher : Elsevier
ISBN 13 : 0323160018
Total Pages : 217 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Pentose Phosphate Pathway by : Terry Wood

Download or read book The Pentose Phosphate Pathway written by Terry Wood and published by Elsevier. This book was released on 2012-12-02 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pentose Phosphate Pathway aims to explore the pentose phosphate cycle and the practical techniques applied in its investigation. The main focus of the book is the pentose phosphate cycle in animals as well as microorganisms, and does not discuss the one related to photosynthesis. The book covers the formulation of the pathway, its types, and its alternative formulations; the preparation, processes, and analysis of the pathway; and the enzymes involved. Also covered in the book are the intermediates in intact cells and tissues; distribution of enzymes among different tissues and species; the operation, regulation, and overall control of the pathway; and the clinical, nutritional, and metabolic aspects of the pathway. The text is recommended for biologists and biochemists who would like to understand further the pentose phosphate pathway and the processes related to it.

Astrocytic-neuronal-astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA

Author : Leif Hertz
Publisher : Frontiers E-books
ISBN 13 : 2889192431
Total Pages : 169 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Astrocytic-neuronal-astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA by : Leif Hertz

Download or read book Astrocytic-neuronal-astrocytic Pathway Selection for Formation and Degradation of Glutamate/GABA written by Leif Hertz and published by Frontiers E-books. This book was released on 2014-04-30 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinological research early recognized the importance of intercellular interactions and realized the importance of glutamatergic and GABAergic signaling. In turn this signalling depends on elaborate interactions between astrocytes and neurons, without which neurons would be unable to produce, reuse and metabolize transmitter glutamate and GABA. Details of these subjects are described in this Research Topic by key investigators in this field. It focuses on the intricate and extremely swift pathway producing these amino acid transmitters from glucose in brain but also discusses difficulties in determining expression of some of the necessary genes in astrocytes and related processes in pancreatic islets. However, it does not discuss how closely associated astrocytes and neurons are anatomically, enabling these interactions. This is elegantly shown in this cover image, kindly provided by Professor Andreas Reichenbach (University of Leipzig, Germany).

Phosphoinositide 3-kinase Signalling Pathway: The Key To Cell Proliferation And Death

Author : Lam Eric Wing-fai
Publisher : World Scientific Publishing Company
ISBN 13 : 1911299204
Total Pages : 252 pages
Book Rating : 4.9/5 (112 download)

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Book Synopsis Phosphoinositide 3-kinase Signalling Pathway: The Key To Cell Proliferation And Death by : Lam Eric Wing-fai

Download or read book Phosphoinositide 3-kinase Signalling Pathway: The Key To Cell Proliferation And Death written by Lam Eric Wing-fai and published by World Scientific Publishing Company. This book was released on 2006-06-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at advanced undergraduates, postgraduates and researchers, this important textbook provides a detailed description of the structure and mechanisms of phosphoinositide 3-kinase (PI3Ks) signalling of all classes, with focus on the cellular context of PI3K activity, including its relevance to normal tissue and diseased states.This book contains a general review chapter detailing the mechanisms of cell proliferation and apoptosis, which are two of the main cellular targets of PI3K signalling. In addition, it provides a detailed description of the role of PI3K on the regulation of FOXO proteins, which are now becoming one of the most closely studied and important proteins in the regulation of cell death, cell proliferation and senescence./a

Ascorbate-Glutathione Pathway and Stress Tolerance in Plants

Author : Naser A. Anjum
Publisher : Springer Science & Business Media
ISBN 13 : 9048194040
Total Pages : 455 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Ascorbate-Glutathione Pathway and Stress Tolerance in Plants by : Naser A. Anjum

Download or read book Ascorbate-Glutathione Pathway and Stress Tolerance in Plants written by Naser A. Anjum and published by Springer Science & Business Media. This book was released on 2010-08-20 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants are sessile organisms that live under a constant barrage of biotic and abiotic insults. Both biotic and abiotic stress factors have been shown to affect various aspects of plant system including the acceleration in the formation of reactive oxygen species (ROS). The ascorbate (AsA)-glutathione (GSH) pathway is a key part of the network of reactions involving enzymes and metabolites with redox properties for the detoxification of ROS, and thus to avert the ROS-accrued oxidative damage in plants. The present book mainly deals with the information gained through the cross-talks and inter-relationship studies on the physiological, biochemical and molecular aspects of the cumulative response of various components of AsA-GSH pathway to stress factors and their significance in plant stress tolerance.

Application of Bioinformatics in Cancers

Author : Chad Brenner
Publisher : MDPI
ISBN 13 : 3039217887
Total Pages : 418 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Application of Bioinformatics in Cancers by : Chad Brenner

Download or read book Application of Bioinformatics in Cancers written by Chad Brenner and published by MDPI. This book was released on 2019-11-20 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability to analyze highly complex data sets to identify factors critical to cancer biology. Novel deep learning algorithms represent an emerging and highly valuable approach for collecting, characterizing and predicting clinical outcomes data. The collection highlights several of these approaches that are likely to become the foundation of research and clinical practice in the future. In fact, many of these technologies reveal new insights about basic cancer mechanisms by integrating data sets and structures that were previously immiscible. Accordingly, the series presented here bring forward a wide range of artificial intelligence approaches and statistical methods that can be applied to imaging and genomics data sets to identify previously unrecognized features that are critical for cancer. Our hope is that these articles will serve as a foundation for future research as the field of cancer biology transitions to integrating electronic health record, imaging, genomics and other complex datasets in order to develop new strategies that improve the overall health of individual patients.

Targeting the Broadly Pathogenic Kynurenine Pathway

Author : Sandeep Mittal
Publisher : Springer
ISBN 13 : 3319118706
Total Pages : 422 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Targeting the Broadly Pathogenic Kynurenine Pathway by : Sandeep Mittal

Download or read book Targeting the Broadly Pathogenic Kynurenine Pathway written by Sandeep Mittal and published by Springer. This book was released on 2015-11-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway and various disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targeted therapies directed at altering the kynurenine pathway of tryptophan metabolism. The initial and rate-limiting step of tryptophan metabolism is mediated by one of two enzymes, tryptophan-2,3-dioxygenase (TDO; predominantly in the liver, but also in the brain) and indoleamine-2,3-dioxygenase (IDO; in a host of tissues in response to immune activation). Targeting the enzymes IDO and TDO, as well as other downstream effectors would therefore be likely to generate novel treatment options that would be helpful in a wide variety of clinical settings. This book provides a unique bridge between basic mechanistic understanding of the role of the kynurenine pathway with translational applications and clinical relevance. It will explore the indications that tryptophan metabolism is a potential biomarker of disease activity, can contribute to local and possibly systemic immune suppression in cancer, and is an attractive target for which a variety of inhibitors are readily available.

Metabolic Pathway Design

Author : Pablo Carbonell
Publisher : Springer Nature
ISBN 13 : 3030298655
Total Pages : 168 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Metabolic Pathway Design by : Pablo Carbonell

Download or read book Metabolic Pathway Design written by Pablo Carbonell and published by Springer Nature. This book was released on 2019-11-05 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.

Pathway Design for Industrial Fermentation

Author : Walter Koch
Publisher : John Wiley & Sons
ISBN 13 : 3527352759
Total Pages : 501 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Pathway Design for Industrial Fermentation by : Walter Koch

Download or read book Pathway Design for Industrial Fermentation written by Walter Koch and published by John Wiley & Sons. This book was released on 2024-01-16 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathway Design for Industrial Fermentation Explore the industrial fermentation processes of chemical intermediates In Pathway Design for Industrial Fermentation, distinguished researcher Dr. Walter Koch delivers an expert overview on industrial fermentation production technology as compared with natural extraction, organic chemistry, and biocatalysis. The book offers key insights for professionals designing and monitoring fermentation processes. The author explores the applications, alternative production, biochemical pathways, metabolic engineering strategy, and downstream processing of various products—including C1 to C6 products—with a focus on low-value products with market prices below 4€ per kilogram. Products will include methane, ethane, acetate, lactic acid, alanine, and others. With specific commentary and insightful perspectives on the cost drivers and technological aspects critical to commercially successful applications, the book also includes: Thorough introductions to methane, ethanol, acetate, lactic acid, alanine, and 3-Hydroxypropionic acid Comprehensive explorations of 1,3-Propanediol, butanol, isobutanol, and isobutene Practical discussions of 1,4-butanediol, succinic acid, itaconic acid, and glutamic acid Fulsome treatments of isoprene, pentamethylenediamine, lysine, citric acid, and adipic acid Perfect for process engineers, biotechnologists, and chemical engineers, Pathway Design for Industrial Fermentation will also benefit biochemists and professionals working in the chemical and food industries.

JAK-STAT Pathway in Disease

Author : Jr., Richard H. Bell
Publisher : CRC Press
ISBN 13 : 1498713769
Total Pages : 191 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis JAK-STAT Pathway in Disease by : Jr., Richard H. Bell

Download or read book JAK-STAT Pathway in Disease written by Jr., Richard H. Bell and published by CRC Press. This book was released on 2009-06-11 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current understanding of the biological roles of the signal transducer and activator of transcription (STAT) proteins and their dysregulation in diseases. STAT proteins were named after their role as signal transducers and activators of transcription. STAT proteins are highly conserved among species, thus reflecting the importance

Ethylene Biology and Beyond: Novel Insights in the Ethylene Pathway and its Interactions

Author : Dominique Van Der Straeten
Publisher : Frontiers Media SA
ISBN 13 : 288963678X
Total Pages : 204 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Ethylene Biology and Beyond: Novel Insights in the Ethylene Pathway and its Interactions by : Dominique Van Der Straeten

Download or read book Ethylene Biology and Beyond: Novel Insights in the Ethylene Pathway and its Interactions written by Dominique Van Der Straeten and published by Frontiers Media SA. This book was released on 2020-05-21 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Hippo Signaling Pathway and Cancer

Author : Moshe Oren
Publisher : Springer Science & Business Media
ISBN 13 : 1461462207
Total Pages : 345 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis The Hippo Signaling Pathway and Cancer by : Moshe Oren

Download or read book The Hippo Signaling Pathway and Cancer written by Moshe Oren and published by Springer Science & Business Media. This book was released on 2013-03-19 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many leading scientists are showing increased interest in this growing field and it's relation to cancer. The chapters in this volume cover virtually all aspects of tumor biology, because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Ras, Wnt, TGFbeta and p53. Moreover, Hippo signaling is not solely involved in regulating “classic” tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. The primary audience are researchers interested in basic science in the areas of tumor suppression, cell cycle and size regulation, development and differentiation.

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors

Author : Kaisorn Chaichana
Publisher : Academic Press
ISBN 13 : 0128117834
Total Pages : 506 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors by : Kaisorn Chaichana

Download or read book Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors written by Kaisorn Chaichana and published by Academic Press. This book was released on 2019-03-15 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them. Provides a comprehensive review of different approaches, explaining them step-by- step Includes diagrams that show surgical approaches Presents the advantages and disadvantages of each approach to aid in decision-making

The Metabolic Pathway Engineering Handbook, Two Volume Set

Author : Christina Smolke
Publisher : CRC Press
ISBN 13 : 1420005626
Total Pages : 1247 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Metabolic Pathway Engineering Handbook, Two Volume Set by : Christina Smolke

Download or read book The Metabolic Pathway Engineering Handbook, Two Volume Set written by Christina Smolke and published by CRC Press. This book was released on 2009-08-18 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Christina Smolke, who recently developed a novel way to churn out large quantities of drugs from genetically modified brewer's yeast, is regarded as one of the most brilliant minds in biomedical engineering. In this handbook, she brings together pioneering scientists from dozens of disciplines to provide a complete record of accomplishment in metab