Part 1 : Efforts Towards the Total Synthesis of Scyphostatin; Part II: Synthetic Studies Towards Peloruside A

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ISBN 13 :
Total Pages : 476 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Part 1 : Efforts Towards the Total Synthesis of Scyphostatin; Part II: Synthetic Studies Towards Peloruside A by : Manomi A. Tennakoon

Download or read book Part 1 : Efforts Towards the Total Synthesis of Scyphostatin; Part II: Synthetic Studies Towards Peloruside A written by Manomi A. Tennakoon and published by . This book was released on 2001 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Studies Towards a Total Synthesis of Scyphostatin

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (593 download)

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Book Synopsis Studies Towards a Total Synthesis of Scyphostatin by : Karen A. Runcie

Download or read book Studies Towards a Total Synthesis of Scyphostatin written by Karen A. Runcie and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Investigations Towards the Total Synthesis of Scyphostatin

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (277 download)

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Book Synopsis Investigations Towards the Total Synthesis of Scyphostatin by : Neil G. Stevenson

Download or read book Investigations Towards the Total Synthesis of Scyphostatin written by Neil G. Stevenson and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Part 1--Studies on an Approach to the Total Synthesis of (+)-pancratistatin Via an Episulfonium Cation ; Part 2--Synthetic, Structural and Thermal Studies of Bisenediyne Macrocycles

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ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.:/5 (451 download)

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Book Synopsis Part 1--Studies on an Approach to the Total Synthesis of (+)-pancratistatin Via an Episulfonium Cation ; Part 2--Synthetic, Structural and Thermal Studies of Bisenediyne Macrocycles by : Heather Smith Blanchette

Download or read book Part 1--Studies on an Approach to the Total Synthesis of (+)-pancratistatin Via an Episulfonium Cation ; Part 2--Synthetic, Structural and Thermal Studies of Bisenediyne Macrocycles written by Heather Smith Blanchette and published by . This book was released on 1999 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Part I. Total Synthesis and Structural Revision of (±)-Tricholomalides A and B. Part II. Synthetic Studies Towards (+)-Cortistatin A

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ISBN 13 :
Total Pages : pages
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Book Synopsis Part I. Total Synthesis and Structural Revision of (±)-Tricholomalides A and B. Part II. Synthetic Studies Towards (+)-Cortistatin A by : Zhang Wang

Download or read book Part I. Total Synthesis and Structural Revision of (±)-Tricholomalides A and B. Part II. Synthetic Studies Towards (+)-Cortistatin A written by Zhang Wang and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part describes the total synthesis and structural revision of (±)-tricholomalides A and B. The synthetic strategy started from a homo-Robinson annulation, followed by a ketene-olefin [2+2] cycloaddition to introduce the lactone ring. Then a Grignard-type reaction appended the isopropenyl moiety, and the synthesis of tricholomalides A and B was achieved. During the course of synthesis, the structures of tricholomalides A and B were revised. The second part describes the synthetic studies towards (+)-cortistatin A, especially the A ring functionalization. The C3 nitrogen was introduced by azide displacement, and C2 hydroxyl was built up by Luche reduction. The challenging C1 functionalization was achieved with bromine-induced methoxymethyl deprotection, and some interesting chemistry was found in this system. The synthetic endeavor set a promising stage for the total synthesis of cortistatin A.

Synthetic Studies

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ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.:/5 (244 download)

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Book Synopsis Synthetic Studies by : Qiang Han

Download or read book Synthetic Studies written by Qiang Han and published by . This book was released on 2005 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dissertation Abstracts International

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ISBN 13 :
Total Pages : 680 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2001 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Part I. Studies Towards the Total Synthesis of (-)-Apoptolidin A ; Part II. Hydroxymethylation of Aldehydes and Its Application to (-)-Rasfonin

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ISBN 13 :
Total Pages : 240 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis Part I. Studies Towards the Total Synthesis of (-)-Apoptolidin A ; Part II. Hydroxymethylation of Aldehydes and Its Application to (-)-Rasfonin by : Douglas J. Tusch

Download or read book Part I. Studies Towards the Total Synthesis of (-)-Apoptolidin A ; Part II. Hydroxymethylation of Aldehydes and Its Application to (-)-Rasfonin written by Douglas J. Tusch and published by . This book was released on 2017 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Part I. A Scalable Synthesis of (−)-rasfonin Enabled by a Convergent Enantioselective [alpha]-hydroxymethylation Strategy

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ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.:/5 (114 download)

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Book Synopsis Part I. A Scalable Synthesis of (−)-rasfonin Enabled by a Convergent Enantioselective [alpha]-hydroxymethylation Strategy by : Justin Michael Niziol

Download or read book Part I. A Scalable Synthesis of (−)-rasfonin Enabled by a Convergent Enantioselective [alpha]-hydroxymethylation Strategy written by Justin Michael Niziol and published by . This book was released on 2020 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Part I. A scalable synthesis of (-)-rasfonin enabled by a convergent enantioselective [alpha]-hydroxymethylation strategy. A scalable total synthesis of (-)-rasfonin, a potent antitumor agent, has been achieved. The synthetic strategy features a highly convergent approach based on a single protocol construction of both molecular hemispheres via catalytic enantioselective a-hydroxymethylation of simple aliphatic aldehydes. The described route has been successful in near-gram quantities of the natural product and serves as the first synthetic strategy to provide sufficient material for broad biological testing. With a keen focus on efficiency, atom economy, cost, and overall yield, the synthetic route described herein is certainly the shortest and most effective way currently described to synthesize significant quantities of (-)-rasfonin. Part II. Studies towards the total synthesis of FK-506. The synthesis of advanced intermediates towards the total synthesis of FK-506 is described herein. FK-506 has been an interesting synthetic target for some time, as it is not only structurally complex, but also a highly potent immunosuppressant. The purpose of the synthesis is to provide FK-506 in its natural form, as well as provide the option for late-stage functionalization in order to manipulate its level of toxicity. Our synthesis towards FK-506 is highly convergent, relying on the synthesis and combination of 4 subunits. Using a modified Julia olefination reaction, the major subunits of FK-506 have been successfully coupled to provide highly advanced structures. The following work also shows the improvement in yield, scalability, and simplicity of numerous reactions in the multiple routes towards the target molecule."--Pages ix-x.

Synthetic Studies Toward the Total Synthesis of Sirodesmin A

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ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis Synthetic Studies Toward the Total Synthesis of Sirodesmin A by : Daniel James Conatser

Download or read book Synthetic Studies Toward the Total Synthesis of Sirodesmin A written by Daniel James Conatser and published by . This book was released on 1982 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthetic Studies Towards Psychrophilin C and Total Synthesis of Psychrophilin E

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ISBN 13 :
Total Pages : 177 pages
Book Rating : 4.:/5 (999 download)

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Book Synopsis Synthetic Studies Towards Psychrophilin C and Total Synthesis of Psychrophilin E by : Tack Ngen

Download or read book Synthetic Studies Towards Psychrophilin C and Total Synthesis of Psychrophilin E written by Tack Ngen and published by . This book was released on 2016 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Doctoral Dissertations

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ISBN 13 :
Total Pages : 816 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Doctoral Dissertations by :

Download or read book American Doctoral Dissertations written by and published by . This book was released on 2000 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Total Synthesis of Natural Products

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Publisher : Springer Science & Business Media
ISBN 13 : 3642340652
Total Pages : 292 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Total Synthesis of Natural Products by : Jie Jack Li

Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

Endohedral Metallofullerenes

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Publisher : CRC Press
ISBN 13 : 1466593954
Total Pages : 276 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Endohedral Metallofullerenes by : Xing Lu

Download or read book Endohedral Metallofullerenes written by Xing Lu and published by CRC Press. This book was released on 2014-12-10 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge on endohedral metallofullerenes (EMFs) has increased dramatically during the last decade. Numerous research findings have been reported, making it an opportune time to provide a systematic update on EMFs. Endohedral Metallofullerenes: Basics and Applications presents the most comprehensive review on all aspects of EMFs including their gen

Combinatorial Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9780471126874
Total Pages : 288 pages
Book Rating : 4.1/5 (268 download)

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Book Synopsis Combinatorial Chemistry by : Stephen R. Wilson

Download or read book Combinatorial Chemistry written by Stephen R. Wilson and published by John Wiley & Sons. This book was released on 1997-03-28 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new time-saving revolution in drug discovery. Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation. Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development. Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes: * Concepts and terms of combinatorial chemistry * Polymer-supported synthesis of organic compounds * Macro beads as microreactors * Solid-phase methods in combinatorial chemistry * Encoded combinatorial libraries, including Rf-encoding of synthesis beads * Strategies for combinatorial libraries of oligosaccharides * Combinatorial libraries of peptides, proteins, and antibodies using biological systems. While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.

Hypervalent Iodine Chemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 3540441077
Total Pages : 275 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Hypervalent Iodine Chemistry by : Thomas Wirth

Download or read book Hypervalent Iodine Chemistry written by Thomas Wirth and published by Springer Science & Business Media. This book was released on 2003-02-12 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: T. Wirth: Introduction and General Aspects.- M. Ochiai: Reactivities, Properties and Structures.- A. Varvoglis: Preparation of Hypervalent Iodine Compounds.- V.V. Zhdankin: C-C-Bond Forming Reactions.- G.F. Koser: C- Heteroatom-Bond Forming Reactions.- G.F. Koser: Heteroatom- Heteroatom-Bond Forming Reactions.- T. Wirth: Oxidations and Rearrangements.- H. Tohma, Y. Kita: Synthetic Applications (Total Synthesis and Natural Product Synthesis).

Hypervalent Iodine in Organic Synthesis

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Publisher : Academic Press
ISBN 13 : 0080534368
Total Pages : 245 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Hypervalent Iodine in Organic Synthesis by : A. Varvoglis

Download or read book Hypervalent Iodine in Organic Synthesis written by A. Varvoglis and published by Academic Press. This book was released on 1996-11-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the fascinating chemistry of the many kinds of organic compounds of hypervalent iodine. Each chapter deals with a particular iodine compound or families of compounds which have been used as reagents in a plethora of useful transformations. These include assorted oxidation, such as with the precious Dess-Martin reagent as well as with a wide range of further reactions. Prominent features of hypervalent iodine reagents derived from iodobenzene are: ready availability, operational simplicity, mild reaction conditions, and high efficiency. They are environmentally safe and can be recycled. New species may be easily prepared by introducing substituents in the benzene ring or changing the ligand attached to iodine. Their combination with other reagents broadens considerably their synthetic potential. Today, no synthetic chemist can afford to ignore the valuable hypervalentiodine reagents. - Features up-to-date coverage of a wide range of topics - Includes many tables featuring a diversity of reactivity, and a comprehensive index - Acts as a comprehensive, up-to-date reference on all aspects of hypervalent iodine chemistry - Contains a section on unusual efficiency of hypervalent iodine reactions