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Author : R. M. Maizels
Publisher : CUP Archive
ISBN 13 : 9780521419277
Total Pages : 246 pages
Book Rating : 4.4/5 (192 download)
Download or read book Parasite Antigens, Parasite Genes written by R. M. Maizels and published by CUP Archive. This book was released on 1991 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes; 8.
Author : Steven A. Frank
Publisher : Princeton University Press
ISBN 13 : 9780691095950
Total Pages : 364 pages
Book Rating : 4.0/5 (959 download)
Download or read book Immunology and Evolution of Infectious Disease written by Steven A. Frank and published by Princeton University Press. This book was released on 2002-07-21 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description
Author : D. Wakelin
Publisher : Cambridge University Press
ISBN 13 : 9780521589369
Total Pages : 96 pages
Book Rating : 4.5/5 (893 download)
Download or read book Genetics of Host and Parasite written by D. Wakelin and published by Cambridge University Press. This book was released on 1996 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of articles, edited by D. Wakelin and D. Walliker include: Genetic variability in parasites and host-parasite interactions; Host genetics and infectious disease; T cell and cytokine basis of host variability in response to intestinal nematode infections; The role of MHC- and non-MHC-associated genes in determining the human immune response to malaria antigens; Influence of host and parasite genotypes on immunological control of Theileria parasites; Genetic susceptibility to leishmanial infections: studies in mice and man; Genetic susceptibility to malaria and other infectious diseases: from MHC to the whole genome. This volume is the specially commissioned supplement to the journal Parasitology, volume 112.
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309045278
Total Pages : 312 pages
Book Rating : 4.0/5 (452 download)
Download or read book Malaria written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Author : Derek Wakelin
Publisher : Cambridge University Press
ISBN 13 : 9780521436359
Total Pages : 226 pages
Book Rating : 4.4/5 (363 download)
Download or read book Immunity to Parasites written by Derek Wakelin and published by Cambridge University Press. This book was released on 1996-08-13 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasites cause many important diseases in humans and domestic animals, malaria being an example. Parasites have evolved to exploit hosts' bodies whereas hosts have evolved immune systems to control infections. Host-parasite interactions therefore provide fascinating examples of evolutionary 'arms-races' in which the immune system plays a key role. Modern research in immunoparasitology is directed towards understanding and exploiting the capacity to develop effective anti-parasite immunity. By concentrating on selected infections where research has made significant progress, Immunity to Parasites provides a clear account of how host immune responses operate and how parasites can evade immunity. The experimental basis of this research is emphasised throughout. This completely updated second edition includes an expanded section on anti-parasite vaccines. The text is aimed at undergraduates and postgraduates with interests in either parasitology or immunology and provides introductory sections on these topics to lead the reader into the later chapters.
Author : Terry W. Pearson
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)
Download or read book Parasite Antigens written by Terry W. Pearson and published by Marcel Dekker. This book was released on 1986 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alister G. Craig
Publisher : Elsevier
ISBN 13 : 0080475884
Total Pages : 464 pages
Book Rating : 4.0/5 (84 download)
Download or read book Antigenic Variation written by Alister G. Craig and published by Elsevier. This book was released on 2003-08-20 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body. The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour. Comprehensive coverage of antigenic variation from viruses to parasites Discussions devoted to molecular mechanisms of host evasion Detailed descriptions of host/pathogen interactions
Author : Malcolm W. Kennedy
Publisher : CRC Press
ISBN 13 : 9780850667721
Total Pages : 264 pages
Book Rating : 4.6/5 (677 download)
Download or read book Parasitic Nematodes SH Antigens, Membranes & Genes written by Malcolm W. Kennedy and published by CRC Press. This book was released on 1991-07-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of current knowledge of nematode parasites which cause widespread mortality and disability in both man and animal, resulting in major economic and clinical implications and of the molecular techniques which are now being used to understand immunological mechanisms.
Author : L.H.T. Van Der Ploeg
Publisher : Elsevier
ISBN 13 : 0323155669
Total Pages : 330 pages
Book Rating : 4.3/5 (231 download)
Download or read book Immune Recognition and Evasion: Molecular Aspects of Host–Parasite Interaction written by L.H.T. Van Der Ploeg and published by Elsevier. This book was released on 2012-12-02 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Recognition and Evasion: Molecular Aspects of Host-Parasite Interaction reviews recent advances in understanding the genetic basis of host-parasite interactions, with emphasis on antigenic epitopes, the genetics of parasites, the molecular mechanisms of immune recognition and evasion, and the way that cytokines and hormones act on host-parasite interactions. Organized into four parts encompassing 25 chapters, this volume begins with an overview of the genomic organization of the T cell receptor genes and the contribution of non-B DNA structures to switch recombination in immunoglobulin genes. It then discusses signal transduction by class II molecules encoded by the major histocompatibility complex la and the biological consequences of this process; allelic polymorphism of HLA class II antigens and its connection to the molecular basis of autoimmunity; mimicry between HLAB27 and bacteria; and genetic control of susceptibility to helminth infection. The reader is also introduced to recognition of protein antigens by antibodies; recognition of influenza antigens by class I-restricted cytotoxic T lymphocytes; the biochemical basis of cachexia of infection; mechanisms of antigenic variation in Plasmodium; and rational design of trypanocidal drugs. Geneticists and molecular biologists will gain valuable information from this book.
Author : Julia Walochnik
Publisher : Springer
ISBN 13 : 3709114160
Total Pages : 547 pages
Book Rating : 4.7/5 (91 download)
Download or read book Molecular Parasitology written by Julia Walochnik and published by Springer. This book was released on 2016-10-20 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on “the molecules” of protozoan parasites – on their genomes, proteomes, glycomes and lipidomes.
Author : R.M.E. Parkhouse
Publisher : Springer Science & Business Media
ISBN 13 : 3662091976
Total Pages : 263 pages
Book Rating : 4.6/5 (62 download)
Download or read book Parasite Antigens in Protection, Diagnosis and Escape written by R.M.E. Parkhouse and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 2-3 billion people in the less developed countries suffer from infections, often multiple, caused by a variety of parasitic organisms. These infections are frequently debilitat ing rather than fatal, and the toll in human misery is fearsome. To this may be added the prevalence of similar diseases in do mestic animals, which diminish supplies of animal pro tein. As the world population increases, the already enormous problem also continues to grow. The resources of the less developed nations are inadequate for solving the problem, and in the de veloped countries a lack of interest in tropical diseases has meant low priority for research. Two recent methodological advances now raise the real possibility of a systematic and effec tive attack upon these diseases - hybridoma and recombinant nucleic acid technologies. The combination ofthese with the still necessary clinical, parasitological and imrnunological in formation permits a logical, planned and realistic approach to diagnosis and treatment. The central aim ofthese modem tech niques is to define antigens with regard to diagnosis, protection and pathology. In the case of some diseases, work has already commenced along these lines; in the case of others, knowledge lags a long way behind. This volume represents a summary of current knowledge about a wide, representative spectrum of tropical diseases. There is considerable common ground between the different infections as regards objectives and the methods for achieving them.
Author :
Publisher : Academic Press
ISBN 13 : 0128209593
Total Pages : 914 pages
Book Rating : 4.1/5 (282 download)
Download or read book Toxocara and Toxocariasis written by and published by Academic Press. This book was released on 2020-05-05 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxocara and Toxocariasis, Volume 109 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history, all topics which help to shape current thinking and applications. This latest release includes chapters on organism and the recognition of the disease, dogs (and cats) disease, diagnosis, prevalence of infection, and treatment, and more. Informs and updates on all the latest developments in the field of parasitology Contains contributions from leading authorities and industry experts Features reviews of more traditional areas, such as zoology, taxonomy and life history, which help to shape current thinking and applications
Author : John Marchalonis
Publisher : Springer Science & Business Media
ISBN 13 : 1468445715
Total Pages : 512 pages
Book Rating : 4.4/5 (684 download)
Download or read book Immunobiology of Parasites and Parasitic Infections written by John Marchalonis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomena involved in infections of man and domestic animals with metazoan or protozoan parasites present formidable practical problems as well as a theoretical challenge to immunologists, molecular biologists, and evolu tionary biologists. With respect to the public health and economic problems, malaria, for example, remains a major health problem with approximately 200 million people being infected yearly and, on the basis of World Health Organiza tion estimates, more than 1 million children die each year of malaria infections (Chapter 4). This volume addresses state-of-the-art immunologic approaches to the development of vaccines for parasitic diseases (Chapter 9) and analyses of studies bearing on the antigenic characterization of protozoan and metazoan parasites (Chapters 4, 5, and 7), on investigations of the role of precise mecha nisms underlying natural resistance or non permissiveness of the host to parasitic infections (Chapters 1, 2, and 12), on induced mechanisms including the genera tion of parasite-specific T-cell lines and clones (Chapter 6), and on the generation of monoclonal antibodies (Chapters 4 and 5) to parasite antigens of distinct de velopmental stages. Great progress has been made in characterizing parasite antigens capable of inducing a protective response in the vaccinated host; further progress in this area strongly depends on biochemistry and molecular biology with the long-term goal of synthesizing such antigens chemically or producing them by means of recombinant DNA technology (Chapter 4).
Author : Joseph Marr
Publisher : Elsevier
ISBN 13 : 9780080527888
Total Pages : 349 pages
Book Rating : 4.5/5 (278 download)
Download or read book Biochemistry and Molecular Biology of Parasites written by Joseph Marr and published by Elsevier. This book was released on 1995-09-06 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms. Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.
Author : Mukesh Samant
Publisher : Academic Press
ISBN 13 : 0128227982
Total Pages : 281 pages
Book Rating : 4.1/5 (282 download)
Download or read book Pathogenesis, Treatment and Prevention of Leishmaniasis written by Mukesh Samant and published by Academic Press. This book was released on 2021-08-18 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment Discusses novel approaches to study parasite infection and treatment Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies
Author : George Robert Coatney
Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.:/5 (31 download)
Download or read book The Primate Malarias written by George Robert Coatney and published by . This book was released on 1971 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Toni Aebischer
Publisher : Frontiers Media SA
ISBN 13 : 2889454851
Total Pages : 294 pages
Book Rating : 4.8/5 (894 download)
Download or read book Parasite Infections: From Experimental Models to Natural Systems written by Toni Aebischer and published by Frontiers Media SA. This book was released on 2018-07-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eukaryotic parasites (including parasitic protozoans, worms and arthropods) are more complex and heterogeneous organisms than pathogenic bacteria and viruses. This notion implies different evolutionary strategies of host exploitation. Typically, parasites establish long-term infections and induce relatively little mortality, as they often limit pathological changes by modulating host cells and downregulating adverse immune responses. Their pattern of distribution tends to be endemic rather than epidemic. Despite these seemingly benign traits, parasites usually cause substantial chronic morbidity, thus constituting an enormous socioeconomic burden in humans, particularly in resource poor countries, and in livestock worldwide. Parasite-induced fitness costs are an evolutionary force that can shape populations and contribute to species diversity. Therefore, a thorough understanding of parasites and parasitic diseases requires detailed knowledge of the respective biochemical, molecular and immunological aspects as well as of population genetics, epidemiology and ecology. This Research Topic (RT) bridges disciplines to connect molecular, immunological and wildlife aspects of parasitic infections. The RT puts emphases on four groups of parasites: Plasmodium, Toxoplasma, Giardia and intestinal helminths. Co-infections are also covered by the RT as they represent the most common form of parasite infections in wildlife and domestic animal populations. Within the four types of parasites the following topics are addressed: (1) Experimental models: hypothesis testing, translation and limits. (2) Critical appraisal of experimental models. (3) Natural systems: Technological advances for investigations in natural parasite-host systems and studies in natural systems. (4) The urgent need for better models and methods in natural parasite systems. Hence, the RT covers and illustrate by the means of four main parasitic infections the parasite-host system at the molecular, cellular and organismic level.
