P J Barnes, P I

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Publisher : Lulu.com
ISBN 13 : 1312205091
Total Pages : 138 pages
Book Rating : 4.3/5 (122 download)

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Book Synopsis P J Barnes, P I by : J Russell Rose

Download or read book P J Barnes, P I written by J Russell Rose and published by Lulu.com. This book was released on 2014-05-19 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polly Jean Davis, born to a rural Appalachian farm family, marries her high school sweetheart, Doug Barnes, after graduation, ending her dream of attending the University of Virginia. After enduring twelve years of marriage to an unfaithful husband, she seizes an opportunity to reclaim her dream and redefine her life. Upon arrival in Charlottesville, hoping to earn money to help pay for college, she takes a job working with Rick Beeson, a Private Investigator. Polly soon finds herself engulfed in the underworld of drug dealers, assassins and corporate greed. More than once Polly longs for the shelter and the safety of her Appalachian Mountain home - but the life she has found and the love of a kind and gentle man are stronger than the pull of her mountain roots.

Journal

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Publisher :
ISBN 13 :
Total Pages : 734 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Journal by : American Chamber of Commerce of the Philippines

Download or read book Journal written by American Chamber of Commerce of the Philippines and published by . This book was released on 1921 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt:

OAR Cumulative Index of Research Results

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Publisher :
ISBN 13 :
Total Pages : 788 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis OAR Cumulative Index of Research Results by :

Download or read book OAR Cumulative Index of Research Results written by and published by . This book was released on with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Chamber of Commerce Journal

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Publisher :
ISBN 13 :
Total Pages : 735 pages
Book Rating : 4.L/5 ( download)

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Book Synopsis American Chamber of Commerce Journal by : American Chamber of Commerce of the Philippines

Download or read book American Chamber of Commerce Journal written by American Chamber of Commerce of the Philippines and published by . This book was released on 1921 with total page 735 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction

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Publisher : Springer
ISBN 13 : 303487362X
Total Pages : 425 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction by : David Raeburn

Download or read book Airways Smooth Muscle: Peptide Receptors, Ion Channels and Signal Transduction written by David Raeburn and published by Springer. This book was released on 2012-12-06 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Airway Smooth Muscle in Health and Disease

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Publisher : Springer Science & Business Media
ISBN 13 : 1461307791
Total Pages : 325 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Airway Smooth Muscle in Health and Disease by : R.F. Coburn

Download or read book Airway Smooth Muscle in Health and Disease written by R.F. Coburn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: I organized this book because there is a need to put together in book form recent advances in our knowledge of how airway smooth muscle:works in health and in disease. After a period when it seemed that progress was very slow, there has been in the past few years an incredibly rapid gathering of knowledge in this area. In particular, our understanding has improved regarding the cascades of events that follow the initial binding of agonist to plasma membrane receptors and that lead to the cross-bridge movements that determine contraction. This advance in our knowledge was stimulated by use of single-and whole-cell channel recordings of plasma membrane currents and by description of the l3-receptor-GTP-binding protein-adenylate cyclase-cAMP coupling system, which serves as a model for other coupling mechanisms. The discovery of the receptor-activated inositol phospholipid transduction system has greatly stimulated research and led to advances in our understanding of mechanisms involved in smooth muscle con traction. Major advances were also triggered by the development of indicators for measuring free cytosolic calcium concentration and starting the unraveling of 2 the events involved in Ca + -dependent activation of contractile proteins. Al though most of the studies that led to our current understanding of these areas were performed on nonairway smooth muscle, these studies usually add to our understanding of airway smooth muscle, and there is an enlarging body of data that have been obtained on airway smooth muscle.

Obstructive Airway Diseases

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Publisher : CRC Press
ISBN 13 : 1439851417
Total Pages : 381 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Obstructive Airway Diseases by : Abhijit Ray

Download or read book Obstructive Airway Diseases written by Abhijit Ray and published by CRC Press. This book was released on 2016-04-19 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Incidences of inflammatory airway diseases are on the rise across the world. Existing therapeutic options are ineffective, unsafe, and expensive, and severe cases are nonresponsive to conventional therapy. Therefore, it is imperative that research be undertaken to discover new treatment options. Obstructive Airway Diseases: Role of Lipid Mediators discusses clinically successful and potential lipid targets that can make a difference in treating some of the most intractable disease states. Topics discussed include: Obstructive airway diseases, etiology, pathophysiology, and existing therapeutic options What constitutes a lipid and how it is broken down to generate biologically active mediators The role of enzymes in the process of lipid mediator synthesis The biology of arachidonic acid, platelet-activating factor, and lysophosphatidic acid and the role they play in airway inflammation Products of arachidonic acid metabolism such as leukotrienes, prostaglandins, epieicosatrienoic acid, and oxoeicosatetraenoic acid Proresolution lipid mediators in inflammatory airway disease conditions The role of sphingosine and ceramide in inflammatory airway disease Protein kinases activated by lipid mediators and those that trigger the generation of lipid messengers The combined input of a panel of international authorities on lipid mediators makes this volume a valuable resource for all those involved in researching, teaching, and studying airway inflammation as well as those involved in drug discovery research. Punit Srivastava maintains a blog with additional information about the book and his work.

OAR Quarterly Index of Current Research Results

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Publisher :
ISBN 13 :
Total Pages : 800 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis OAR Quarterly Index of Current Research Results by : United States. Air Force. Office of Aerospace Research

Download or read book OAR Quarterly Index of Current Research Results written by United States. Air Force. Office of Aerospace Research and published by . This book was released on 1959 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Childhood Asthma

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Publisher : CRC Press
ISBN 13 : 084935224X
Total Pages : 740 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Childhood Asthma by : Stanley J Szefler

Download or read book Childhood Asthma written by Stanley J Szefler and published by CRC Press. This book was released on 2005-09-26 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference collects the latest studies on the development, diagnosis, and treatment of childhood asthma and offers current perspectives on new technologies that will shape the management of pediatric asthma in the forthcoming decade-illustrating how advances in pulmonary function measurement, inflammatory markers, imaging, and pharmacogenetics

Multiphoton Microscopy in the Biomedical Sciences

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Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Multiphoton Microscopy in the Biomedical Sciences by :

Download or read book Multiphoton Microscopy in the Biomedical Sciences written by and published by . This book was released on 2006 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Sensory Nerves and Neuropeptides in Gastroenterology

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Publisher : Springer Science & Business Media
ISBN 13 : 1489907440
Total Pages : 304 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Sensory Nerves and Neuropeptides in Gastroenterology by : Marcello Costa

Download or read book Sensory Nerves and Neuropeptides in Gastroenterology written by Marcello Costa and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past 15 years much evidence has accumulated which indicates the paramount importance of sensory nerves in reg ulating functions of the gastrointestinal tract. In parallel, the attention of researchers in this field has been increas ingly attracted to the role played by neuropeptides in the normal and diseased gut. Basic research on the peculiar properties of capsaicin, the pungent ingredient from plants of the genus Capsicum, has allowed the gap between these two areas of research to be bridged. Sincethen, the study of gut afferents and neuropeptides has become more and more interconnected and recognized as a major avenue to understand ing the pathophysiology of various human diseases. It is widely recognized that a certain subset of primary afferents synthesize, store and release neuropeptides (such as tachykin nins and calcitonin gene-related peptide) from their central and peripheral endings, the latter being widely distributed in the alimentary canal and related organs (liver, pancreas). The First International Meeting on Sensory Nerves and Neuropeptides in Gastroenterology, held in Florence from December 4-5, 1989, sponsored and organized by Fondazione Internazionale Menarini, aimed to focus the current status of research in this field. The contributions presented at the meeting and in this book delineate a suggestive scenario in which sensory nerves of the gut, and the multiple messages they carry through the release of neuropeptides, are to be considered as a major target for the development of new drugs potentially useful in a number of diseases of the gastro intestinal tract.

Allergic Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 1475725914
Total Pages : 434 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Allergic Diseases by : Phil Lieberman

Download or read book Allergic Diseases written by Phil Lieberman and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise, easy-to-read, comprehensive, and up-to-date guide designed to help primary care physicians, pediatricians, and internists with the day-to-day diagnosis and treatment of their allergic patients. Its distinguished contributors-all highly experienced clinicians-integrate our latest understanding of the basic mechanisms of allergic disease and develop state-of-the-art treatment protocols that allow busy physicians to sharpen their allergy management strategies significantly. "Summary Boxes" utilized throughout book summarize crucial points and processes for time-pressured physicians, allowing them to quickly grasp a therapeutic situation and determine the best and most up-to-date treatment options. Each chapter contains numerous figures and tables to enhance understanding, treatment algorithms, and a list of suggested readings carefully chosen to deepen knowledge and insight into key points.

Handbook of Cell Signaling

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Publisher : Academic Press
ISBN 13 : 0080920918
Total Pages : 3188 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Handbook of Cell Signaling by : Ralph A. Bradshaw

Download or read book Handbook of Cell Signaling written by Ralph A. Bradshaw and published by Academic Press. This book was released on 2009-11-03 with total page 3188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field

Essentials of Genomic and Personalized Medicine

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Publisher : Academic Press
ISBN 13 : 0080958117
Total Pages : 851 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Essentials of Genomic and Personalized Medicine by : Geoffrey S. Ginsburg

Download or read book Essentials of Genomic and Personalized Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2009-10-02 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human disease. From principles, methodology and translational approaches to genome discoveries and clinical applications, Essentials of Genomic and Personalized Medicine will be a valuable resource for various professionals and students across medical disciplines, including human genetics and genomics, oncology, neuroscience, gene therapy, molecular medicine, pharmacology, and biomedical sciences. Updates with regard to diagnostic testing, pharmacogenetics, predicting disease susceptibility, and other important research components as well as chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, present this book as an essential tool for a variety of professionals and students who are endeavouring into the developing the diverse and practical field of genomic and personalized medicine. - Full color throughout - Includes contributions on genetic counselling, ethical, legal/regulatory, and social issues related to the practice of genomic medicine from leaders in the field - Introductory chapter highlights differences between personalized and traditional medicine, promising areas of current research, and challenges to incorporate the latest research discoveries and practic - Ancillary material includes case studies and lab questions which highlight the collaborative approach to the science

Pharmacology of Asthma

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Publisher : Springer Science & Business Media
ISBN 13 : 364275855X
Total Pages : 333 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Pharmacology of Asthma by : Clive P. Page

Download or read book Pharmacology of Asthma written by Clive P. Page and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much of this new information is brought together in this volume written by inter nationally recognised authorities. The aim of the book is to review in depth the changing concepts of inflammatory processes in asthma and to discuss the implications for research of this common chronic disease. Many of the advances in and future therapy our understanding of asthma have originated from a pharmacological approach, and this volume highlights the promising new options for pharma cological intervention. It is hoped this book will be invaluable for research scientists and clinic ians involved in asthma research and will be a major reference resource for chest physicians and those involved in the development of novel pharmaceu tical entities. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this growing area. c.P. PAGE P.l. BARNES Contents CHAPTER 1 The Pathology of Asthma: An Overview L.A. LAmNEN and A. LAmNEN. With 10 Figures ...................... 1 A. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 1 . . . . . . . . . . . . . . . B. Methods to Investigate the Pathology of Human Asthma ............ 1 C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks ........................... 2 I. Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 4 . . . . . . . . . . . . . . II. Eosinophils ............................................... 7 III. Neutrophils.............................................. 10 D. Bronchial Epithelial Inflammation During an Asthma Attack. . . . . .. . 10 E. Epithelial Regeneration .... . . . . . . . . . . . . . . . . . . . . . . .. . . 12 . . . . . . . . .

Graph Drawing

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Publisher : Springer
ISBN 13 : 3642002196
Total Pages : 472 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Graph Drawing by : Ioannis G. Tollis

Download or read book Graph Drawing written by Ioannis G. Tollis and published by Springer. This book was released on 2009-02-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 16th International Symposium on Graph Drawing (GD 2008) was held in Hersonissos, near Heraklion, Crete, Greece, September 21-24, 2008, and was attended by 91 participants from 19 countries. In response to the call for papers the Program Committee received 83 s- missions,eachdescribing originalresearchand/or a systemdemonstration.Each submissionwasreviewedbyatleastthreeProgramCommitteemembersandthe reviewer’s comments were returned to the authors. Following extensive disc- sions, the committee accepted 31 long papers and 8 short papers. In addition, 10 posters were accepted and displayed at the conference site. Each poster was granted a two-page description in the conference proceedings. Two invited speakers, Jesper Tegn ́ er from Karolinska Institute (Monday) and Roberto Tamassia from Brown University (Tuesday), gave fascinating talks during the conference. Professor Tegn ́ er focused on the challenges and oppor- nities posed by the discovery, analysis, and interpretation of biological networks to information visualization, while Prof. Tamassia showed how graph drawing techniques can be used as an e?ective tool in computer security and pointed to future research directions in this area. Following what is now a tradition, the 15th Annual Graph Drawing Contest was held during the conference, also including a Graph Drawing Challenge to the conference attendees. A report is included in the conference proceedings.

Disease Markers in Exhaled Breath

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Publisher : CRC Press
ISBN 13 : 0203909194
Total Pages : 546 pages
Book Rating : 4.2/5 (39 download)

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Book Synopsis Disease Markers in Exhaled Breath by : Nandor Marczin

Download or read book Disease Markers in Exhaled Breath written by Nandor Marczin and published by CRC Press. This book was released on 2002-10-22 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: With nearly 1700 references, Disease Markers in Exhaled Breath is essential reading for pulmonologists; anesthesiologists; physiologists; chest, pulmonary, thoracic, and cardiovascular physicians and surgeons; asthmologists; and upper-level undergraduate, graduate, and medical school students in these disciplines. It discusses the potential diagnos