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Oxidative Stress And Chronic Degenerative Diseases
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Book Synopsis Oxidative Stress and Chronic Degenerative Diseases by : Jose Antonio Morales-Gonzalez
Download or read book Oxidative Stress and Chronic Degenerative Diseases written by Jose Antonio Morales-Gonzalez and published by BoD – Books on Demand. This book was released on 2013-05-22 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.
Book Synopsis Oxidative Stress and Neurodegenerative Disorders by : G. Ali Qureshi
Download or read book Oxidative Stress and Neurodegenerative Disorders written by G. Ali Qureshi and published by Elsevier. This book was released on 2007-03-22 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders * Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems
Book Synopsis Oxidative Stress and Antioxidant Defense by : Sahab Uddin
Download or read book Oxidative Stress and Antioxidant Defense written by Sahab Uddin and published by . This book was released on 2019-07-25 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Antioxidant Defense: Biomedical Value in Health and Diseases represent current findings on the impact of oxidative stress in the pathogenesis of diseases and underlying mechanisms of antioxidants influencing health and disease processes. This book is divided into seven sections that describe how antioxidants defend oxidative stressmediated diseases as well as recent developments, future opportunities, and challenges. Sections 1 analyzes the role of oxidative stress in aging and associated diseases as well as the use of antioxidants in health maintenance, preventing and repairing injuries caused by oxidative stress. Section 2 represents the status of various antioxidants in cigarette smoking and antioxidant defense against exerciseinduced oxidative stress. Section 3 focuses on the effect of oxidative stress in the pathogenesis of neurodegeneration and the existing status of antioxidant therapy. Section 4 covers the impact of oxidative stress at different levels of chronic degenerative diseases, as well as treatment with antioxidants to revert and diminish the cellular injury. Section 5 offers the importance of antioxidants in abating the pathological processes involved in hypertension and stroke. Section 6 presents the complexity associated with oxidative stress and metabolic disorders as well as the potential of antioxidants used in amelioration of related pathologies. Section 7 discusses the antioxidant defense against oxidative stressmediated erectile dysfunctions and the significance of antioxidants in pregnancy. This book represents the copious set of specific research updates and diaphanous understanding of oxidative stressmediated cellular damages and role of antioxidants in disease processes from experienced and eminent academicians, researchers, and scientists from throughout the world. This book is suitable for professionals, academicians, students, researchers, scientists and industrialists around the world in the biomedical, health, and life science fields.
Book Synopsis Novel Therapeutic Approaches Targeting Oxidative Stress by : Pawan Kumar Maurya
Download or read book Novel Therapeutic Approaches Targeting Oxidative Stress written by Pawan Kumar Maurya and published by Academic Press. This book was released on 2022-02-18 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives. Explores oxidative stress in a variety of diseases, including neurological disorders, cardiovascular diseases, age-related diseases, and cancer Covers a range of therapeutic approaches to target oxidative stress Includes chapters on the application of novel drug delivery systems and diagnostic biosensors to oxidative stress Features case studies illustrating the targeting of oxidative stress
Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur
Book Synopsis Role of Oxidative Stress in Chronic Diseases by : Isaias Dichi
Download or read book Role of Oxidative Stress in Chronic Diseases written by Isaias Dichi and published by CRC Press. This book was released on 2014-03-14 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent findings on the role of oxidative stress in chronic diseases. Understanding the mechanisms behind it enables readers to comprehend the rationale which underlies intervention in such conditions. The book places special emphasis on genetic polymorphism—an important issue related to this field of study. It covers the role of oxidative stress in transmissible disorders as well as non-transmissible chronic conditions with chapters on metabolic diseases, autoimmune and neurodegenerative diseases, and cancer and cachexia. Each chapter covers a different disorder and the efficacy of interventional procedures.
Book Synopsis Role of Oxidative Stress in Pathophysiology of Diseases by : Pawan K. Maurya
Download or read book Role of Oxidative Stress in Pathophysiology of Diseases written by Pawan K. Maurya and published by Springer Nature. This book was released on 2020-06-15 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress. Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.
Book Synopsis Oxidative Stress and Aging by : R.C. Cutler
Download or read book Oxidative Stress and Aging written by R.C. Cutler and published by Birkhäuser. This book was released on 2012-12-06 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and aging Over the past several years there has been an extraordinarily rapid growth in our knowledge of free radical chemistry and its possible involvement in both normal essential biology and age related disease and dysfunction. Much of this growth in the traditionally separate sciences of chemistry and molecular gerontology occurred independently, with little interaction or communi cation between the scientists working in these two fields. In view of the growing maturity of the two fields and the potential importance of advancing our knowledge in the area of oxidative stress and aging, we perceived a critical need to organize an international conference the "First Inter national Conference on Oxidative Stress and Aging" in Hawaii in 1994 to bring together the world's leading scientists in the fields of reactive oxygen species and molecular gerontology. The objective of this conference was to provide a unique opportunity for scholars working in these two related and rapidly growing fields to participate in the exchange, integration, and synthesis of new concepts and ideas, to engage in constructive criticism and to initiate new collaborative research projects. The conference focused on the molecular and cellular aspects of aging as related to oxidative stress. It was one of the largest and most comprehensive international conferences held in molecular gerontology. At this conference a call was made for submission of papers to be used in the publication of a book covering the major contributions of the meeting.
Book Synopsis Oxidative Stress and Related Diseases: Volume II by : Nick Gilmour
Download or read book Oxidative Stress and Related Diseases: Volume II written by Nick Gilmour and published by . This book was released on 2015-01-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collaborative effort for progressing towards the prevention and treatment of chronic degenerative diseases. It responds to the urge to find, in a sole document, the impact of oxidative stress at distinct levels, as well as treatment with antioxidants to react and decrease the damage. The book includes two sections namely, aging and therapy- a role for antioxidants. Researchers from across the world have contributed in it. The book is intended for health professionals and those interested in combating stress.
Book Synopsis Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases by : Luc Montagnier
Download or read book Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases written by Luc Montagnier and published by CRC Press. This book was released on 1997-10-06 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV.
Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell
Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by Oxford University Press. This book was released on 2015 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.
Book Synopsis Mitochondrial Dysfunction by : Lawrence H. Lash
Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author :W.Wolfgang Fleischhacker Publisher :Springer Science & Business Media ISBN 13 :3709161371 Total Pages :154 pages Book Rating :4.7/5 (91 download)
Book Synopsis Stroke-Vascular Diseases by : W.Wolfgang Fleischhacker
Download or read book Stroke-Vascular Diseases written by W.Wolfgang Fleischhacker and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis, the underlying cause of heart attacks, strokes and peripheral vascular disease, is one of the major killers in the world. By 2020 WHO statistics indicate that it will be the most common cause of morbidity and mortality in both the industrialised world and the underdeveloped world. The disease develops slowly over many years in the innermost layer of large and medium-sized arteries (Fig. 1) (Scott, 1995; Ross, 1999; Naumova and Scott, 2000; Glass and Witztum, 2001; Libby, 2001). It does not usually become manifest before the fourth of fifth decade, but then often strikes with devas tating suddenness. Fifty per cent of individuals still die (25 per cent immedi ately) from their first heart attack; and morbidity from coronary heart disease and stroke is very significant. The disease has a profound impact on health care services and on industrial economies. The lesions of atherosclerosis Autopsy studies show that in humans atherosclerosis begins in the first and second decade of life. A similar disease can be produced in experimental animals, where diet and genetics can be manipulated to produce identical lesions. The earliest lesions are fatty streaks. These consist of an accumulation of lipid-engorged macrophages (foam cells) and T and B lymphocytes in the arterial intima. With time, the fatty streaks progress to intermediate lesions, composed of foam cells and smooth muscle cells.
Book Synopsis Inflammation, Aging, and Oxidative Stress by : Stephen C. Bondy
Download or read book Inflammation, Aging, and Oxidative Stress written by Stephen C. Bondy and published by Springer. This book was released on 2016-12-14 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular disease, particle-induced inflammation and cardiovascular disease, Alzheimer’s disease, ovarian aging, dietary and endogenous anti-oxidants in management of Parkinson’s disease, and effects of exercise on oxidation and inflammation. The nineteen expertly authored chapters are organized into three sections in order to present a complete picture to the reader: Age Related Cellular Events, Role of Inflammatory and Oxidative Processes in Age-Related Diseases, and Retardation of Cellular Aging. Inflammation, Oxidative Stress and Age-Related Disease draws from a variety of international perspectives and provides a comprehensive overview of the relationship between disease, cell aging, and oxidative stress, as well as potential for preventing or slowing these processes. This installment of Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice is ideal for researchers, clinicians, and advanced graduate students in the fields of cardiology, neuroscience, biogerontolgy, and cell biology.
Book Synopsis Oxidative Stress and Related Diseases: Volume I by : Nick Gilmour
Download or read book Oxidative Stress and Related Diseases: Volume I written by Nick Gilmour and published by . This book was released on 2015-01-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book responds to the urge to find, in a sole document, the impact of oxidative stress at distinct levels as well as treatment with antioxidants to react and decrease the damage. The contents of the book are grouped under two sections: cell biology, chemical free radicals & antioxidants and cell damage by oxidative stress. It is intended for health professionals, as researchers from across the world have contributed in it. The book is a collaborative effort for progressing towards the prevention and treatment of chronic degenerative diseases.
Book Synopsis A Master Regulator of Oxidative StressThe Transcription Factor Nrf2 by : Jose Antonio Morales-Gonzalez
Download or read book A Master Regulator of Oxidative StressThe Transcription Factor Nrf2 written by Jose Antonio Morales-Gonzalez and published by BoD – Books on Demand. This book was released on 2016-12-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.
Book Synopsis Glutathione System and Oxidative Stress in Health and Disease by :
Download or read book Glutathione System and Oxidative Stress in Health and Disease written by and published by BoD – Books on Demand. This book was released on 2020-08-26 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The imbalance between the production of reactive oxygen species (ROS) and antioxidant defenses determines a state known as oxidative stress. Higher levels of pro-oxidants compared to antioxidant defenses may generate oxidative damage, which, in turn, may lead to modifications in cellular proteins, lipids, and DNA, reducing functional capacity and increasing the risk of diseases. Nevertheless, the clearance of harmful reactive chemical species is achieved by the antioxidant defense systems. These protection systems are referred to as the first and second lines of defense and comprise the classic antioxidants, enzymatic and nonenzymatic defenses, including glutathione. This book presents and discusses the advancement of research on health and diseases and their underlying mechanisms, exploring mainly aspects related to the glutathione antioxidant system.
