Optimization Of Behavioral Biobehavioral And Biomedical Interventions

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Optimization of Behavioral, Biobehavioral, and Biomedical Interventions

Author : Linda M. Collins
Publisher : Springer
ISBN 13 : 3319917765
Total Pages : 301 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Optimization of Behavioral, Biobehavioral, and Biomedical Interventions by : Linda M. Collins

Download or read book Optimization of Behavioral, Biobehavioral, and Biomedical Interventions written by Linda M. Collins and published by Springer. This book was released on 2018-07-28 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This book provides additional information on a principled empirical framework for developing interventions that are more effective, efficient, economical, and scalable. This framework is introduced in the monograph, "Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy (MOST)" by Linda M. Collins (Springer, 2018). The present book is focused on advanced topics related to MOST. The chapters, all written by experts, are devoted to topics ranging from experimental design and data analysis to development of a conceptual model and implementation of a complex experiment in the field. Intervention scientists who are preparing to apply MOST will find this book an important reference and guide for their research. Fields to which this work pertains include public health (medicine, nursing, health economics, implementation sciences), behavioral sciences (psychology, criminal justice), statistics, and education.

Optimization of Behavioral, Biobehavioral, and Biomedical Interventions

Author : Linda M. Collins
Publisher : Springer
ISBN 13 : 3319722069
Total Pages : 297 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Optimization of Behavioral, Biobehavioral, and Biomedical Interventions by : Linda M. Collins

Download or read book Optimization of Behavioral, Biobehavioral, and Biomedical Interventions written by Linda M. Collins and published by Springer. This book was released on 2018-02-08 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a framework for development, optimization, and evaluation of behavioral, biobehavioral, and biomedical interventions. Behavioral, biobehavioral, and biomedical interventions are programs with the objective of improving and maintaining human health and well-being, broadly defined, in individuals, families, schools, organizations, or communities. These interventions may be aimed at, for example, preventing or treating disease, promoting physical and mental health, preventing violence, or improving academic achievement. This volume introduces the multiphase optimization strategy (MOST), pioneered at The Methodology Center at the Pennsylvania State University, as an alternative to the classical approach of relying solely on the randomized controlled trial (RCT). MOST borrows heavily from perspectives taken and approaches used in engineering, and also integrates concepts from statistics and behavioral science, including the RCT. As described in detail in this book, MOST consists of three phases: preparation, in which the conceptual model underlying the intervention is articulated; optimization, in which experimentation is used to gather the information necessary to identify the optimized intervention; and evaluation, in which the optimized intervention is evaluated in a standard RCT. Through numerous examples, the book demonstrates that MOST can be used to develop interventions that are more effective, efficient, economical, and scalable. Optimization of Behavioral, Biobehavioral, and Biomedical Interventions: The Multiphase Optimization Strategy is the first book to present a comprehensive introduction to MOST. It will be an essential resource for behavioral, biobehavioral, and biomedical scientists; statisticians, biostatisticians, and analysts working in epidemiology and public health; and graduate-level courses in development and evaluation of interventions.

Fostering Healthy Mental, Emotional, and Behavioral Development in Children and Youth

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 030948202X
Total Pages : 391 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Fostering Healthy Mental, Emotional, and Behavioral Development in Children and Youth by : National Academies of Sciences, Engineering, and Medicine

Download or read book Fostering Healthy Mental, Emotional, and Behavioral Development in Children and Youth written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-18 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthy mental, emotional, and behavioral (MEB) development is a critical foundation for a productive adulthood. Much is known about strategies to support families and communities in strengthening the MEB development of children and youth, by promoting healthy development and also by preventing and mitigating disorder, so that young people reach adulthood ready to thrive and contribute to society. Over the last decade, a growing body of research has significantly strengthened understanding of healthy MEB development and the factors that influence it, as well as how it can be fostered. Yet, the United States has not taken full advantage of this growing knowledge base. Ten years later, the nation still is not effectively mitigating risks for poor MEB health outcomes; these risks remain prevalent, and available data show no significant reductions in their prevalence. Fostering Healthy Mental, Emotional, and Behavioral Development in Children and Youth: A National Agenda examines the gap between current research and achievable national goals for the next ten years. This report identifies the complexities of childhood influences and highlights the need for a tailored approach when implementing new policies and practices. This report provides a framework for a cohesive, multidisciplinary national approach to improving MEB health.

Handbook of Evidence-Based Prevention of Behavioral Disorders in Integrated Care

Author : William O’Donohue
Publisher : Springer Nature
ISBN 13 : 3030834697
Total Pages : 466 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Handbook of Evidence-Based Prevention of Behavioral Disorders in Integrated Care by : William O’Donohue

Download or read book Handbook of Evidence-Based Prevention of Behavioral Disorders in Integrated Care written by William O’Donohue and published by Springer Nature. This book was released on 2021-12-14 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is a comprehensive, authoritative and up-to-date source on prevention technologies specifically for integrated care settings. It covers general issues related to prevention including the practical issues of financing, and staffing, and a general introduction to the advantages of prevention efforts. It covers a range of behavioral health disorders using an approach that is most relevant to the practitioner: it provides basic definitions, and describes the specific roles of both the primary care provider (PCP) and the behavioral care provider (BCP) as well as specific resources presented in a stepped care model. Stepped care has been used sucessfully in medical settings. Adapted to behavioral health settings, It allows the clinician and the patient to choose treatments that are tailored to specific levels of intensity. This handbook is an interdisciplinary resource useful for classes in integrated care as well as for clinicians employed in in these settings.

Evidence-Based Practice in Action

Author : Sona Dimidjian
Publisher : Guilford Publications
ISBN 13 : 1462539769
Total Pages : 465 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis Evidence-Based Practice in Action by : Sona Dimidjian

Download or read book Evidence-Based Practice in Action written by Sona Dimidjian and published by Guilford Publications. This book was released on 2019-08-30 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The evidence-based practice (EBP) movement has always been about implementing optimal health care practices. Practitioners have three primary roles they can play in relation to the research evidence in EBP: scientists, systematic reviewers, and research consumers. Learning EBP is an acculturation process begun during professional training that seamlessly integrates research and practice"--Provided by publisher.

The Oxford Handbook of Self-Determination Theory

Author : Professor Emeritus of Psychology Richard M Ryan
Publisher : Oxford University Press
ISBN 13 : 0197600042
Total Pages : 1249 pages
Book Rating : 4.1/5 (976 download)

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Book Synopsis The Oxford Handbook of Self-Determination Theory by : Professor Emeritus of Psychology Richard M Ryan

Download or read book The Oxford Handbook of Self-Determination Theory written by Professor Emeritus of Psychology Richard M Ryan and published by Oxford University Press. This book was released on 2023-01-18 with total page 1249 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Self-determination theory (SDT) represents a comprehensive framework for the study of human motivation, personality development and wellness as evidenced by the breadth and variety of chapters in this handbook. In introducing this collection, we review the basic assumptions, philosophy of science, methods, and mission of SDT. We also provide a brief history of SDT, linking various developments within the theory to the contributions found in this volume. Finally, we attempt to place SDT within the landscape of past and contemporary theoretical psychology, as well as modern historical and cultural developments, in part explaining the continued growth of SDT's basic research and real-world applications"--

The Handbook of Behavior Change

Author : Martin S. Hagger
Publisher : Cambridge University Press
ISBN 13 : 1108750117
Total Pages : 730 pages
Book Rating : 4.1/5 (87 download)

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Book Synopsis The Handbook of Behavior Change by : Martin S. Hagger

Download or read book The Handbook of Behavior Change written by Martin S. Hagger and published by Cambridge University Press. This book was released on 2020-07-15 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social problems in many domains, including health, education, social relationships, and the workplace, have their origins in human behavior. The documented links between behavior and social problems have compelled governments and organizations to prioritize and mobilize efforts to develop effective, evidence-based means to promote adaptive behavior change. In recognition of this impetus, The Handbook of Behavior Change provides comprehensive coverage of contemporary theory, research, and practice on behavior change. It summarizes current evidence-based approaches to behavior change in chapters authored by leading theorists, researchers, and practitioners from multiple disciplines, including psychology, sociology, behavioral science, economics, philosophy, and implementation science. It is the go-to resource for researchers, students, practitioners, and policy makers looking for current knowledge on behavior change and guidance on how to develop effective interventions to change behavior.

Frontiers in Psychiatry

Author : Yong-Ku Kim
Publisher : Springer Nature
ISBN 13 : 9813297212
Total Pages : 641 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Frontiers in Psychiatry by : Yong-Ku Kim

Download or read book Frontiers in Psychiatry written by Yong-Ku Kim and published by Springer Nature. This book was released on 2019-11-09 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.

Applications of the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents

Author : Jill Ehrenreich-May
Publisher : Oxford University Press
ISBN 13 : 0197527930
Total Pages : 217 pages
Book Rating : 4.1/5 (975 download)

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Book Synopsis Applications of the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents by : Jill Ehrenreich-May

Download or read book Applications of the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents written by Jill Ehrenreich-May and published by Oxford University Press. This book was released on 2021 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/UP-A; Ehrenreich-May et al., 2018) are transdiagnostic interventions designed to address multiple diagnoses, diagnostic categories, and/or problem types within a single treatment protocol. It might be said that modern transdiagnostic interventions originated within the early years of the twenty-first century with theoretical and empirical work by Barlow and colleagues conceptualizing a "unified approach" to understanding and treating emotional disorders (e.g., Barlow, Allen, & Choate, 2004) and, subsequently, the initial publication of the Unified Protocols for Transdiagnostic Treatment of Emotional Disorders (Barlow et al., 2011). However, up until the mid-twentieth century, psychotherapeutic approaches were nothing if not transdiagnostic, in that they addressed underlying psychodynamic and interpersonal processes theorized to lead to the development of broad psychological neuroses. This approach changed during the second half of the twentieth century, in accordance with two parallel and mutually informative developments. First, with each new iteration of the American Psychiatric Association's Diagnostic and Statistical Manual Mental Disorders (DSM) from the publication of the original DSM in 1952 to DSM-IV in 1994, the number of diagnoses proliferated, and diagnostic criteria became increasingly fine-grained. During the same historical period, new treatments for these highly specified diagnoses were developed based on new empirical and theoretical evidence (e.g., exposure for phobias), and more rigorous outcomes research on cognitive-behavioral therapy (CBT) and other interventions began to emerge (Barlow et al., 2004). Psychotherapy research was conducted using newly-developed treatment manuals addressing symptoms of highly specific diagnoses (e.g., panic disorder, specific phobias) to help ensure scientific rigor and replicability. The turn back toward transdiagnostic models of psychopathology and treatment at the turn of the twenty-first century was based on growing recognition of the commonalities among psychiatric diagnoses, the shared features of psychotherapeutic interventions for distinct diagnoses, and the beneficial effects of treatments for one diagnosis on other diagnoses, which will be further discussed below"--

Diabetes Digital Health

Author : David C. Klonoff
Publisher : Elsevier
ISBN 13 : 0128174862
Total Pages : 311 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Diabetes Digital Health by : David C. Klonoff

Download or read book Diabetes Digital Health written by David C. Klonoff and published by Elsevier. This book was released on 2020-04-04 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes Digital Health brings together the multifaceted information surrounding the science of digital health from an academic, regulatory, industrial, investment and cybersecurity perspective. Clinicians and researchers who are developing and evaluating mobile apps for diabetes patients will find this essential reading, as will industry people whose companies are developing mobile apps and sensors. Provides valuable information for clinicians, researchers and industry about the design and evaluation of patient-facing diabetes adherence technologies Highlights cutting-edge topics that are presented and discussed at the Digital Diabetes Congress

Principles and Practice of Clinical Trials

Author : Steven Piantadosi
Publisher : Springer Nature
ISBN 13 : 3319526367
Total Pages : 2573 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Principles and Practice of Clinical Trials by : Steven Piantadosi

Download or read book Principles and Practice of Clinical Trials written by Steven Piantadosi and published by Springer Nature. This book was released on 2022-07-19 with total page 2573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive major reference work for our SpringerReference program covering clinical trials. Although the core of the Work will focus on the design, analysis, and interpretation of scientific data from clinical trials, a broad spectrum of clinical trial application areas will be covered in detail. This is an important time to develop such a Work, as drug safety and efficacy emphasizes the Clinical Trials process. Because of an immense and growing international disease burden, pharmaceutical and biotechnology companies continue to develop new drugs. Clinical trials have also become extremely globalized in the past 15 years, with over 225,000 international trials ongoing at this point in time. Principles in Practice of Clinical Trials is truly an interdisciplinary that will be divided into the following areas: 1) Clinical Trials Basic Perspectives 2) Regulation and Oversight 3) Basic Trial Designs 4) Advanced Trial Designs 5) Analysis 6) Trial Publication 7) Topics Related Specific Populations and Legal Aspects of Clinical Trials The Work is designed to be comprised of 175 chapters and approximately 2500 pages. The Work will be oriented like many of our SpringerReference Handbooks, presenting detailed and comprehensive expository chapters on broad subjects. The Editors are major figures in the field of clinical trials, and both have written textbooks on the topic. There will also be a slate of 7-8 renowned associate editors that will edit individual sections of the Reference.

Handbook of Health Psychology

Author : Tracey A. Revenson
Publisher : Routledge
ISBN 13 : 1351683268
Total Pages : 732 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Handbook of Health Psychology by : Tracey A. Revenson

Download or read book Handbook of Health Psychology written by Tracey A. Revenson and published by Routledge. This book was released on 2018-12-07 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: This rich resource provides a thorough overview of current knowledge and new directions in the study of the biological, psychological, social, and cultural factors that affect health, health behavior, and illness. Chapters review the latest theories and research with an emphasis on how research is translated into behavioral medicine interventions. Featuring contributions from top researchers and rising stars in the field, authors provide a theoretical foundation; evaluate the empirical evidence; and make suggestions for future research, clinical practice, and policy. The handbook reflects the latest approaches to health psychology today, including: Emphasis throughout on the socio-cultural aspects of health, including socioeconomic status, gender, race/ethnicity, sexual orientation, and age/developmental stage A new section on emerging areas in health psychology, including behavioral genomics, military veterans' health, and digital health Coverage of prevention, interventions, and treatment in the applications section An expansion of the biopsychosocial model across several levels of analysis, including cultural, macro-social, and cellular factors Sustained emphasis on translating research into practice and policy The handbook considers the intersections of concepts (behavior change), populations (women's and sexual minority health), cultural groups (African American, Asian American, and Latino), risk and protective factors (obesity, coping), and diseases (cancer, diabetes, HIV), making it essential reading for scholars of health psychology, public health, epidemiology, and nursing. Novices to the field appreciate the accessibly written chapters, while seasoned professionals appreciate the book's deep, cutting-edge coverage.

Anxiety Disorders in Childhood and Adolescence: Psychopathology, Assessment, and Treatment

Author : Mireia Orgilés
Publisher : Frontiers Media SA
ISBN 13 : 2889765660
Total Pages : 260 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Anxiety Disorders in Childhood and Adolescence: Psychopathology, Assessment, and Treatment by : Mireia Orgilés

Download or read book Anxiety Disorders in Childhood and Adolescence: Psychopathology, Assessment, and Treatment written by Mireia Orgilés and published by Frontiers Media SA. This book was released on 2022-07-14 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Innovative Methods in Child Maltreatment Research and Practice

Author : Chad E. Shenk
Publisher : Springer Nature
ISBN 13 : 3031337395
Total Pages : 300 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Innovative Methods in Child Maltreatment Research and Practice by : Chad E. Shenk

Download or read book Innovative Methods in Child Maltreatment Research and Practice written by Chad E. Shenk and published by Springer Nature. This book was released on 2023-07-08 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the latest methodological advancements in child maltreatment research and practice. It addresses long-standing challenges when working with and serving the child maltreatment population, while offering pragmatic solutions for scientists, caseworkers, and providers. Chapters explore methodological innovations in such areas as screening and detecting child maltreatment, collecting objective data in longitudinal research, causal modeling of adverse health effects, and advancements in both preventive and clinical interventions. Key areas of coverage include methods for: Screening for child maltreatment at the point of contact. Reducing bias and promoting causal inference when examining health effects and etiological processes. Promoting representative samples, objective data collection, and integration of child welfare and medical records to enhance equitable access to care. Intervening with children and families at risk for and exposed to maltreatment. Innovative Methods in Child Maltreatment Research and Practice is a must-have reference for researchers, professors, and graduate students as well as clinicians, therapists, and other professionals in developmental, clinical child, and school psychology.

Developability of Biotherapeutics

Author : Sandeep Kumar
Publisher : CRC Press
ISBN 13 : 1482246155
Total Pages : 297 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Developability of Biotherapeutics by : Sandeep Kumar

Download or read book Developability of Biotherapeutics written by Sandeep Kumar and published by CRC Press. This book was released on 2015-11-18 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism. The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book also addresses a general lack of awareness of the many different contributions that computation can make to biopharmaceutical drug development. This informative and practical reference is a valuable resource for professionals engaged in industrial research and development, scientists working with regulatory agencies, and pharmacy, medicine, and life science students and educators. It focuses primarily on the developability of monoclonal antibody candidates, but the principles described can also be extended to other modalities such as recombinant proteins, fusion proteins, antibody drug conjugates and vaccines. The book is organized into two sections. The first discusses principles and applications of computational approaches toward discovering and developing biopharmaceutical drugs. The second presents best practices in developability assessments of early-stage biopharmaceutical drug candidates. In addition to raising awareness of the promise of computational research, this book also discusses solutions required to improve the success rate of translating biologic drug candidates into products available in the clinic. As such, it is a rich source of information on current principles and practices as well as a starting point for finding innovative applications of computation towards biopharmaceutical drug development.

Mobile Sensing in Psychology

Author : Matthias R. Mehl
Publisher : Guilford Publications
ISBN 13 : 1462553109
Total Pages : 818 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis Mobile Sensing in Psychology by : Matthias R. Mehl

Download or read book Mobile Sensing in Psychology written by Matthias R. Mehl and published by Guilford Publications. This book was released on 2023-12-18 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The possibilities mobile sensing opens up for the social, behavioral, biomedical, and life sciences appear almost infinite and are bound to become even more comprehensive in the years to come. However, data collection with new information technology also poses new challenges for research and applied fields. Is everything that is possible also legally allowed? What are the personal and societal consequences of the possible deep insights into very private areas of life for research ethics and the relations between the researchers and those being researched? How can data be stored so that anonymity and privacy are preserved? How can quality criteria be formulated for this new and rapidly developing field of research? And how can we ensure that information and predictions derived from mobile sensing are psychometrically accurate and practically useful as we move from scientific proof-of-concept measurements to medical/clinical measurements that aim at supporting and improving the diagnostic process? This handbook answers these questions and based on the conviction that a profound understanding and the sound application of mobile sensing methods require specific knowledge and competencies: scientific background and the key concepts, how to generally plan and conduct a mobile sensing study, different methods of data collection with mobile sensing, both in terms of the technological know-how and the methodological how-to, and possibilities and limitations of mobile sensing and of best-practice examples from different areas of application"--

A Guide to Sample Size for Animal-based Studies

Author : Penny S. Reynolds
Publisher : John Wiley & Sons
ISBN 13 : 1119799988
Total Pages : 294 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis A Guide to Sample Size for Animal-based Studies by : Penny S. Reynolds

Download or read book A Guide to Sample Size for Animal-based Studies written by Penny S. Reynolds and published by John Wiley & Sons. This book was released on 2023-08-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Guide to Sample Size for Animal-based Studies Understand a foundational area of experimental design with this innovative reference Animal-based research is an essential part of basic and preclinical research, but poses a unique set of experimental design challenges. The most important of these are the 3Rs − Replacement, Reduction and Refinement − the principles comprising the ethical framework for humane animal-based studies. However, many researchers have difficulty navigating the design trade-offs necessary to simultaneously minimize animal use, and produce scientific information that is both rigorous and reliable. A Guide to Sample Size for Animal-based Studies meets this need with a thorough, accessible reference work to the subject. This book provides a straightforward systematic approach to “rightsizing” animal-based experiments, with sample size estimates based on the fundamentals of statistical thinking: structured research questions, variation control and appropriate design of experiments. The result is a much-needed guide to planning animal-based experiments to ensure scientifically valid and reliable results. This book offers: Step-by-step guidance in diverse methods for approximating and refining sample size Detailed treatment of research topics specific to animal-based research, including pilot, feasibility and proof-of-concept studies Sample size approximation methods for different types of data − binary, continuous, ordinal, time to event − and different study types − description, comparison, nested designs, reference interval construction and dose-response studies Numerous worked examples, using real data from published papers, together with SAS and R code A Guide to Sample Size for Animal-based Studies is a must-have reference for preclinical and veterinary researchers, as well as ethical oversight committees and policymakers.