Optimization Methods for High Dose Rate Brachytherapy Treatment Planning

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Total Pages : 0 pages
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Book Synopsis Optimization Methods for High Dose Rate Brachytherapy Treatment Planning by : Elodie Rachel Mok Tsze Chung

Download or read book Optimization Methods for High Dose Rate Brachytherapy Treatment Planning written by Elodie Rachel Mok Tsze Chung and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optimization approaches for treatment planning in two novel high-dose-rate (HDR) brachytherapy techniques, direction-modulation brachytherapy (DMBT) and energy-modulated brachytherapy (EMBT), are investigated for cervical cancer and prostate cancer. Brachytherapy is a form of radiation therapy where a radioactive source is placed inside the body to irradiate the tumour internally. Conventionally, only one source is used and it is unshielded, thus providing an isotropic dose distribution. DMBT makes use of a new shielded applicator that is capable of delivering highly directional radiation distributions. In EMBT, three HDR sources, 192Ir, 60Co, and 169Yb, are used in combination to provide variety in dose profiles. To investigate the benefit of these two new techniques over conventional brachytherapy, we use an inverse planning approach to generate the treatment plans. We model the treatment planning problem as a quadratic program and use an interior point constraint generation algorithm to generate the treatment plans.

Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization

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Publisher : Linköping University Electronic Press
ISBN 13 : 9179297382
Total Pages : 53 pages
Book Rating : 4.1/5 (792 download)

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Book Synopsis Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization by : Björn Morén

Download or read book Treatment Planning of High Dose-Rate Brachytherapy - Mathematical Modelling and Optimization written by Björn Morén and published by Linköping University Electronic Press. This book was released on 2021-01-12 with total page 53 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a widespread class of diseases that each year affects millions of people. It is mostly treated with chemotherapy, surgery, radiation therapy, or combinations thereof. High doserate (HDR) brachytherapy (BT) is one modality of radiation therapy, which is used to treat for example prostate cancer and gynecologic cancer. In BT, catheters (i.e., hollow needles) or applicators are used to place a single, small, but highly radioactive source of ionizing radiation close to or within a tumour, at dwell positions. An emerging technique for HDR BT treatment is intensity modulated brachytherapy (IMBT), in which static or dynamic shields are used to further shape the dose distribution, by hindering the radiation in certain directions. The topic of this thesis is the application of mathematical optimization to model and solve the treatment planning problem. The treatment planning includes decisions on catheter placement, that is, how many catheters to use and where to place them, as well as decisions for dwell times. Our focus is on the latter decisions. The primary treatment goals are to give the tumour a sufficiently high radiation dose while limiting the dose to the surrounding healthy organs, to avoid severe side effects. Because these aims are typically in conflict, optimization models of the treatment planning problem are inherently multiobjective. Compared to manual treatment planning, there are several advantages of using mathematical optimization for treatment planning. First, the optimization of treatment plans requires less time, compared to the time-consuming manual planning. Secondly, treatment plan quality can be improved by using optimization models and algorithms. Finally, with the use of sophisticated optimization models and algorithms the requirements of experience and skill level for the planners are lower. The use of optimization for treatment planning of IMBT is especially important because the degrees of freedom are too many for manual planning. The contributions of this thesis include the study of properties of treatment planning models, suggestions for extensions and improvements of proposed models, and the development of new optimization models that take clinically relevant, but uncustomary aspects, into account in the treatment planning. A common theme is the modelling of constraints on dosimetric indices, each of which is a restriction on the portion of a volume that receives at least a specified dose, or on the lowest dose that is received by a portion of a volume. Modelling dosimetric indices explicitly yields mixed-integer programs which are computationally demanding to solve. We have therefore investigated approximations of dosimetric indices, for example using smooth non-linear functions or convex functions. Contributions of this thesis are also a literature review of proposed treatment planning models for HDR BT, including mathematical analyses and comparisons of models, and a study of treatment planning for IMBT, which shows how robust optimization can be used to mitigate the risks from rotational errors in the shield placement. Cancer är en grupp av sjukdomar som varje år drabbar miljontals människor. De vanligaste behandlingsformerna är cellgifter, kirurgi, strålbehandling eller en kombination av dessa. I denna avhandling studeras högdosrat brachyterapi (HDR BT), vilket är en form av strålbehandling som till exempel används vid behandling av prostatacancer och gynekologisk cancer. Vid brachyterapibehandling används ihåliga nålar eller applikatorer för att placera en millimeterstor strålkälla antingen inuti eller intill en tumör. I varje nål finns det ett antal så kallade dröjpositioner där strålkällan kan stanna en viss tid för att bestråla den omkringliggande vävnaden, i alla riktningar. Genom att välja lämpliga tider för dröjpositionerna kan dosfördelningen formas efter patientens anatomi. Utöver HDR BT studeras också den nya tekniken intensitetsmodulerad brachyterapi (IMBT) vilket är en variation på HDR BT där skärmning används för att minska strålningen i vissa riktningar vilket gör det möjligt att forma dosfördelningen bättre. Planeringen av en behandling med HDR BT omfattar hur många nålar som ska användas, var de ska placeras samt hur länge strålkällan ska stanna i de olika dröjpositionerna. För HDR BT kan dessa vara flera hundra stycken medan det för IMBT snarare handlar om tusentals möjliga kombinationer av dröjpositioner och inställningar av skärmarna. Planeringen resulterar i en dosplan som beskriver hur hög stråldos som tumören och intilliggande frisk vävnad och riskorgan utsätts för. Dosplaneringen kan formuleras som ett matematiskt optimeringsproblem vilket är ämnet för avhandlingen. De övergripande målsättningarna för behandlingen är att ge en tillräckligt hög stråldos till tumören, för att döda alla cancerceller, samt att undvika att bestråla riskorgan eftersom det kan ge allvarliga biverkningar. Då alla målsättningarna inte samtidigt kan uppnås fullt ut så fås optimeringsproblem där flera målsättningar behöver prioriteras mot varandra. Utöver att dosplanen uppfyller kliniska behandlingsriktlinjer så är också tidsaspekten av planeringen viktig eftersom det är vanligt att den görs medan patienten är bedövad eller sövd. Vid utvärdering av en dosplan används dos-volymmått. För en tumör anger ett dosvolymmått hur stor andel av tumören som får en stråldos som är högre än en specificerad nivå. Dos-volymmått utgör en viktig del av målen för dosplaner som tas upp i kliniska behandlingsriktlinjer och ett exempel på ett sådant mål vid behandling av prostatacancer är att 95% av prostatans volym ska få en stråldos som är minst den föreskrivna dosen. Dos-volymmått utläses ur de kliniskt betydelsefulla dos-volym histogrammen som för varje stråldosnivå anger motsvarande volym som erhåller den dosen. En fördel med att använda matematisk optimering för dosplanering är att det kan spara tid jämfört med manuell planering. Med väl utvecklade modeller så finns det också möjlighet att skapa bättre dosplaner, till exempel genom att riskorganen nås av en lägre dos men med bibehållen dos till tumören. Vidare så finns det även fördelar med en process som inte är lika personberoende och som inte kräver erfarenhet i lika stor utsträckning som manuell dosplanering i dagsläget gör. Vid IMBT är det dessutom så många frihetsgrader att manuell planering i stort sett blir omöjligt. I avhandlingen ligger fokus på hur dos-volymmått kan användas och modelleras explicit i optimeringsmodeller, så kallade dos-volymmodeller. Detta omfattar såväl analys av egenskaper hos befintliga modeller, utvidgningar av tidigare använda modeller samt utveckling av nya optimeringsmodeller. Eftersom dos-volymmodeller modelleras som heltalsproblem, vilka är beräkningskrävande att lösa, så är det också viktigt att utveckla algoritmer som kan lösa dem tillräckligt snabbt för klinisk användning. Ett annat mål för modellutvecklingen är att kunna ta hänsyn till fler kriterier som är kliniskt relevanta men som inte ingår i dos-volymmodeller. En sådan kategori av mått är hur dosen är fördelad rumsligt, exempelvis att volymen av sammanhängande områden som får en alldeles för hög dos ska vara liten. Sådana områden går dock inte att undvika helt eftersom det är typiskt för dosplaner för brachyterapi att stråldosen fördelar sig ojämnt, med väldigt höga doser till små volymer precis intill strålkällorna. Vidare studeras hur små fel i inställningarna av skärmningen i IMBT påverkar dosplanens kvalitet och de olika utvärderingsmått som används kliniskt. Robust optimering har använts för att säkerställa att en dosplan tas fram som är robust sett till dessa möjliga fel i hur skärmningen är placerad. Slutligen ges en omfattande översikt över optimeringsmodeller för dosplanering av HDR BT och speciellt hur optimeringsmodellerna hanterar de motstridiga målsättningarna.

Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176851311
Total Pages : 63 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy by : Björn Morén

Download or read book Mathematical Modelling of Dose Planning in High Dose-Rate Brachytherapy written by Björn Morén and published by Linköping University Electronic Press. This book was released on 2019-04-24 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a widespread type of diseases that each year affects millions of people. It is mainly treated by chemotherapy, surgery or radiation therapy, or a combination of them. One modality of radiation therapy is high dose-rate brachytherapy, used in treatment of for example prostate cancer and gynecologic cancer. Brachytherapy is an invasive treatment in which catheters (hollow needles) or applicators are used to place the highly active radiation source close to or within a tumour. The treatment planning problem, which can be modelled as a mathematical optimization problem, is the topic of this thesis. The treatment planning includes decisions on how many catheters to use and where to place them as well as the dwell times for the radiation source. There are multiple aims with the treatment and these are primarily to give the tumour a radiation dose that is sufficiently high and to give the surrounding healthy tissue and organs (organs at risk) a dose that is sufficiently low. Because these aims are in conflict, modelling the treatment planning gives optimization problems which essentially are multiobjective. To evaluate treatment plans, a concept called dosimetric indices is commonly used and they constitute an essential part of the clinical treatment guidelines. For the tumour, the portion of the volume that receives at least a specified dose is of interest while for an organ at risk it is rather the portion of the volume that receives at most a specified dose. The dosimetric indices are derived from the dose-volume histogram, which for each dose level shows the corresponding dosimetric index. Dose-volume histograms are commonly used to visualise the three-dimensional dose distribution. The research focus of this thesis is mathematical modelling of the treatment planning and properties of optimization models explicitly including dosimetric indices, which the clinical treatment guidelines are based on. Modelling dosimetric indices explicitly yields mixedinteger programs which are computationally demanding to solve. The computing time of the treatment planning is of clinical relevance as the planning is typically conducted while the patient is under anaesthesia. Research topics in this thesis include both studying properties of models, extending and improving models, and developing new optimization models to be able to take more aspects into account in the treatment planning. There are several advantages of using mathematical optimization for treatment planning in comparison to manual planning. First, the treatment planning phase can be shortened compared to the time consuming manual planning. Secondly, also the quality of treatment plans can be improved by using optimization models and algorithms, for example by considering more of the clinically relevant aspects. Finally, with the use of optimization algorithms the requirements of experience and skill level for the planners are lower. This thesis summary contains a literature review over optimization models for treatment planning, including the catheter placement problem. How optimization models consider the multiobjective nature of the treatment planning problem is also discussed.

Optimization of Brachytherapy Treatment Planning Using Adjoint Functions

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Publisher :
ISBN 13 :
Total Pages : 202 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Optimization of Brachytherapy Treatment Planning Using Adjoint Functions by : Sua Yoo

Download or read book Optimization of Brachytherapy Treatment Planning Using Adjoint Functions written by Sua Yoo and published by . This book was released on 2003 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interstitial Brachytherapy

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Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Interstitial Brachytherapy by : Interstitial Collaborative Working Group

Download or read book Interstitial Brachytherapy written by Interstitial Collaborative Working Group and published by Lippincott Williams & Wilkins. This book was released on 1990 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Treatment Plan Optimization for Rotating-shield Brachytherapy

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Publisher :
ISBN 13 :
Total Pages : 129 pages
Book Rating : 4.:/5 (918 download)

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Book Synopsis Treatment Plan Optimization for Rotating-shield Brachytherapy by : Yunlong Liu

Download or read book Treatment Plan Optimization for Rotating-shield Brachytherapy written by Yunlong Liu and published by . This book was released on 2014 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this thesis, we aim to develop fundamentally new techniques and algorithms for efficiently computing rotating-shield brachytherapy (RSBT) treatment plans. We propose that these algorithms will pave the way for making RSBT available in clinical practices. RSBT is an intensity modulated high-dose-rate brachytherapy (HDR-BT) technique. Theoretically, RSBT offers advantages over the conventional HDR-BT. Although this technique is promising in theory, its application in practice is still at an early stage. The RSBT technique entails rotating a radiation-attenuating shield about a brachytherapy source to directionally modulate the radiation in an optimized fashion. The unshielded brachytherapy source used in conventional HDR-BT delivers radially symmetric dose distributions, thus the intensity modulation capability of the conventional HDR-BT is limited. With the capability of making anisotropic radiation, RSBT will revolutionize the brachytherapy technique through superior dose conformity, increased flexibility and inherent accuracy. Due to the enhanced power of intensity-modulation, RSBT will also enable dose escalation without increasing toxicity to the organs-at-risk, thus improving quality of life for millions of cancer patients. Although the first conceptual RSBT method was proposed more than ten years ago, there are still tremendous chges for applying it in clinical practices. Creating efficient and automated treatment planning system is one of the major technical obstacles for making RSBT deliverable in the clinic. The time-critical nature of the application significantly increases the difficulty of RSBT treatment planning, demanding innovative techniques for information integration. Therefore, we propose that fundamentally novel technology and algorithms for RSBT treatment planning can make RSBT clinically accessible. The fundamental concept used for this thesis is to decompose the dose optimization step for RSBT treatment planning into two steps, namely anchor plan optimization and optimal sequencing. The degree of freedom in anchor plan optimization is controlled at a low level compared to single-step dose optimization, and the optimal sequencing algorithms can efficiently calculate treatment plans by reusing the solutions from anchor plan optimization. Thus, by decomposing the dose optimization, the computational complexity in the two-step method is greatly reduced compared to the single-step method. In the anchor plan optimization, an abstract RSBT delivery model is assumed. The abstract RSBT delivery model assumes that only beams with fixed small azimuthal emission angle, which are called beamlets, will be used during the delivery. An anchor plan is created based on this assumption that only these beamlets will be used. Generally, an anchor plan will be of high quality in the sense of dose distribution, but of low quality in the sense that it has prohibitory long delivery time. In the optimal sequencing step, beamlets will be superposed into beams to reduce the delivery time. By limiting the delivery time to a clinically acceptable level, the anchor plans turn into deliverable plans. Unlike anchor plan optimization, where an abstract RSBT delivery model is assumed, the optimal sequencing step depends on more concrete RSBT delivery models. Specifically, we will study three methods of RSBT, namely the single rotating-shield brachytherapy (S-RSBT), the dynamic rotating-shield brachytherapy (D-RSBT) and the paddle rotating-shield brachytherapy (P-RSBT). We proposed a novel anchor plan dose optimization method as well as novel optimal sequencing methods for each of the RSBT delivery methods studied in this work. We have implemented all the proposed algorithms and experimented with them using real medical data. With the methods proposed in this thesis, the optimization time for creating delivery plans can be controlled within 15 minutes based on the data from our experiments. Compared to the conventional brachytherapy techniques, the three methods studied in this work can produce more conformal dose distributions at an acceptable level of delivery time increase. With 15 min/fx delivery time, S-RSBT, D-RSBT and P-RSBT averagely increased the D90 (the minimum dose received by the hottest 90% of the tumor) by 17, 9 and 5 Gy compared to conventional interstitial plus intracavitary brachytherapy, whose D90 is 79 Gy. The best choice depends on the specified delivery time or quality requirement, as well as the complexity of building the equipment. Roughly speaking, among the three RSBT methods studied in this thesis, P-RSBT has the most complex applicators as well as the highest plan qualities. S-RSBT has the simplest applicators, and its plan qualities is generally better than D-RSBT with limited delivery time (

Handbook of Image-Guided Brachytherapy

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Publisher : Springer
ISBN 13 : 3319448277
Total Pages : 630 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Handbook of Image-Guided Brachytherapy by : Jyoti Mayadev

Download or read book Handbook of Image-Guided Brachytherapy written by Jyoti Mayadev and published by Springer. This book was released on 2017-03-21 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a clinically relevant, succinct, and comprehensive overview of image-guided brachytherapy. Throughout the last decade, the utility of image guidance in brachytherapy has increased to enhance procedural development, treatment planning, and radiation delivery in an effort to optimize safety and clinical outcomes. Organized into two parts, the book discusses physics and radiobiology principles of brachytherapy as well as clinical applications of image-guided brachytherapy for various disease sites (central nervous system, eye, head and neck, breast, lung, gastrointestinal, genitourinary, gynecologic, sarcoma, and skin). It also describes the incorporation of imaging techniques such as CT, MRI, and ultrasound into brachytherapy procedures and planning. Featuring procedural and anesthesia care, extensive images, contouring examples, treatment planning techniques, and dosimetry for the comprehensive treatment for each disease site, Handbook of Image-Guided Brachytherapy is a valuable resource for practicing radiation oncologists, physicists, dosimetrists, residents, and medical students.

Achieving Quality in Brachytherapy

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Publisher : CRC Press
ISBN 13 : 1482268574
Total Pages : 267 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Achieving Quality in Brachytherapy by : B.R. Thomadsen

Download or read book Achieving Quality in Brachytherapy written by B.R. Thomadsen and published by CRC Press. This book was released on 1999-01-01 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achieving Quality in Brachytherapy addresses the main issues that often prevent correct delivery of brachytherapy treatment. The book explains how to set up a functional quality assurance program in brachytherapy and covers all the steps needed to undertake particular treatment plans, from the initial planning required to the detailed specification

Comprehensive Brachytherapy

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Publisher : CRC Press
ISBN 13 : 1439844984
Total Pages : 539 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Comprehensive Brachytherapy by : Jack Venselaar

Download or read book Comprehensive Brachytherapy written by Jack Venselaar and published by CRC Press. This book was released on 2012-11-08 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners. Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.

The Use of Machine Learning System in Brachytherapy Treatment Planning

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis The Use of Machine Learning System in Brachytherapy Treatment Planning by : Ximeng Mao

Download or read book The Use of Machine Learning System in Brachytherapy Treatment Planning written by Ximeng Mao and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "High dose rate (HDR) brachytherapy (BT) involves temporarily insertion of a sealed highly radioactive source inside or in close proximity of the target volume, by using catheters and/or applicators. Treatment planning in HDR BT is performed on a 3D set of computerized tomography or magnetic resonance images. The purpose of a treatment plan is to determine where (dwell position) and how long (dwell time) the radiation source should pause to expose its radiation. Each implanted catheter provides a set of possible dwell positions. Combinations of the possible dwell positions and dwell times, as well as utilizing contours of the target volume and organs at risk (OAR), contributes to optimization of treatment plans. The optimal plan has the best possible dose distribution with respect to the target volume and the OAR. Two key questions for treatment planning are how to evaluate a certain plan and how to search for the optimal plan. The traditional solutions to the two questions often lack the capability of fully utilizing previous experience, which result in inefficiency due to long computation times when solving the problems. In this thesis machine learning (ML) algorithms were investigated for evaluation and search for an optimal BT treatment plan. ML-based algorithms are chosen due to their ability to specialize in exploiting previous experience for better future performance. Evaluation of a certain treatment plan in the first problem requires calculation of the radiation dose. Clinical standards for BT dose calculation have traditionally been based on AAPM TG-43 report. In the TG-43 based dose calculation process, the affected malignant tissue, the surrounding radiation sensitive healthy organs, BT seeds, needles and applicators are considered to be water with unit mass density for simplification. This simplification overlooks the alteration of photon fluence and absorption of dose by different tissues, BT seeds, needles or applicators. Model based dose calculation algorithms (MBDCAs) provide a detailed and more accurate method for calculation of absorbed dose in heterogeneous systems such as the human body, with the Monte Carlo (MC) method being the gold standard. Recently, these algorithms have evolved from serving as a research tool into clinical practice in BT. To obtain accurate dose distributions, a correct geometrical description, density and tissue composition of the patient, a model of the BT seed and the implanted applicators with appropriate density and material composition are needed as inputs to these MBDCAs. AAPM TG-186 provides guidance for the use of MBDCAs. Although MC method is the most accurate technique for dose calculations, its use incurs an excessive computational cost and time. To provide a solution for the accuracy-time trade-off, a deep convolutional neural network (CNN) algorithm to predict dose distributions calculated with the MC method has been proposed in this thesis. The developed deep CNN based dose calculation algorithm was shown to be a promising method for accurate patient specific dosimetry in BT, at accuracy arbitrarily close to those of the source MC algorithm but with much faster computation times. Treatment plan optimization is traditionally solved as constrained optimization. Extended from core setup of plan optimization, a related plan analysis problem is formulated to focus on understanding the impacts of individual dwell position to overall plan performance. Derived from linear programming formulation of the optimization problem, reinforcement learning (RL) was applied to solve the plan analysis problem. Relying on the dose distribution at each dwell position, the RL solution showed flexibility in problem formulation as there is no need to enforce linearity. Moreover, when used in a simplified proof-of-concept setup derived from the real clinical case, the fully-trained RL agent showed the capability to reach optimal treatment plan within one step from any random start point"--

Radiation Therapy Physics

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Publisher : Springer Science & Business Media
ISBN 13 : 3662031078
Total Pages : 468 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Radiation Therapy Physics by : Alfred R. Smith

Download or read book Radiation Therapy Physics written by Alfred R. Smith and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide a uniquely comprehensive source of information on the entire field of radiation therapy physics. The very significant advances in imaging, computational, and accelerator technologies receive full consideration, as do such topics as the dosimetry of radiolabeled antibodies and dose calculation models. The scope of the book and the expertise of the authors make it essential reading for interested physicians and physicists and for radiation dosimetrists.

Brachytherapy

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Publisher : Springer Publishing Company
ISBN 13 : 1617052612
Total Pages : 573 pages
Book Rating : 4.6/5 (17 download)

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Book Synopsis Brachytherapy by : Phillip M. Devlin, MD, FACR

Download or read book Brachytherapy written by Phillip M. Devlin, MD, FACR and published by Springer Publishing Company. This book was released on 2015-10-14 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive guide to the latest knowledge and techniques in brachytherapy Since the first edition was published in 2006, Phillip M. Devlinís Brachytherapy has been acknowledged as the essential book on the practice. Inthis updated new edition, all chapters covering cancer sites have been significantly revised. Organized for specialists in several fields, Brachytherapy contains site-specific chapters that discuss how the evolving role of advanced image guidance has demonstrated greater efficacy and less toxicity. Clinical vignettes with images now accompany all site-specific chapters. The chapter on prostate brachytherapy has been expanded to include other indications in the genitourinary system, and there are two entirely new chaptersóone chronicling the history of brachytherapy and the other detailing the emergence of skin brachytherapy. Dr. Devlin, a leading world authority on brachytherapy, has assembled other leaders in the field from world-renowned radiation oncology programs to enrichthis comprehensive text. From new data on medical outcomes to the costs and benefits of running a brachytherapy practice, Brachytherapy, Second Edition is the first and last word on what still is considered the most conformal radiotherapy technique in the field. In the new edition: Over 300 images accompany the chapter text and clinical vignettes Essential tables and spreadsheets enhance the chapter on running a brachytherapy practice Ten years of technological advancements are assimilated and reviewed in each site-specific chapter Includes access to the fully-searchable downloadable ebook From the Foreword: ìAs education is essential to advance awareness of and proficiency in the full spectrum of brachytherapy applications, the appearance of the second edition of this highly regarded text is both a timely and most welcome event. The distinguished list of contributors to this work reads like a veritable ìWhoís Whoî of international brachytherapy expertise making this an indispensable resource for students and practitioners of this complex and challenging modality[Ö]A particularly welcome feature is the clinical vignettes at the close of every chapter that bring seemingly remote concepts to life in real world practical applications[Ö]With the second edition of Brachytherapy: Applications and Techniques, Dr. Devlin and colleagues give us a text that instills a profound appreciation for the critical value of this essential modality. This book makes it clear that brachytherapy not only works, it is an irreplaceable component of contemporary cancer care.î --David Wazer, MD, FACRO, FACR, FASTRO, Professor and Chairman, Departments of Radiation Oncology, Alpert Medical School of Brown University, Providence, RI

Comprehensive Brachytherapy

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Publisher : Taylor & Francis
ISBN 13 : 1439844992
Total Pages : 523 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Comprehensive Brachytherapy by : Jack Venselaar

Download or read book Comprehensive Brachytherapy written by Jack Venselaar and published by Taylor & Francis. This book was released on 2012-11-08 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern brachytherapy is one of the most important oncological treatment modalities requiring an integrated approach that utilizes new technologies, advanced clinical imaging facilities, and a thorough understanding of the radiobiological effects on different tissues, the principles of physics, dosimetry techniques and protocols, and clinical expertise. A complete overview of the field, Comprehensive Brachytherapy: Physical and Clinical Aspects is a landmark publication, presenting a detailed account of the underlying physics, design, and implementation of the techniques, along with practical guidance for practitioners. Bridging the gap between research and application, this single source brings together the technological basis, radiation dosimetry, quality assurance, and fundamentals of brachytherapy. In addition, it presents discussion of the most recent clinical practice in brachytherapy including prostate, gynecology, breast, and other clinical treatment sites. Along with exploring new clinical protocols, it discusses major advances in imaging, robotics, dosimetry, Monte Carlo-based dose calculation, and optimization.

Emerging Technologies in Brachytherapy

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Publisher : CRC Press
ISBN 13 : 1351647288
Total Pages : 491 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Emerging Technologies in Brachytherapy by : William Y. Song

Download or read book Emerging Technologies in Brachytherapy written by William Y. Song and published by CRC Press. This book was released on 2017-05-19 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brachytherapy is continuously advancing. Years of accumulated experience have led to clinical evidence of its benefit in numerous clinical sites such as gynecological, prostate, breast, rectum, ocular, and many other cancers. Brachytherapy continues to expand in its scope of practice and complexity, driven by strong academic and commercial research, by advances in competing modalities, and due to the diversity in the political and economic landscape. It is a true challenge for practicing professionals and students to readily grasp the overarching trends of the field, especially of those technologies and innovative practices that are not yet established but are certainly on the rise. Addressing this challenge, Emerging Technologies in Brachytherapy presents a comprehensive collection of chapters on the latest trending/emerging technologies and expert opinions. It is divided into five broad sections: Section I: Physics of Brachytherapy Section II: Imaging for Brachytherapy Guidance Section III: Brachytherapy Suites Section IV: Is Brachytherapy a Competitive Modality? Section V: Vision 20/20: Industry Perspective Each section has a carefully selected collection of chapters, which covers the spectrum of topics in comprehensive detail. By drawing on recognized experts and key opinion leaders from academia and commercial sectors worldwide (100+ contributors), Emerging Technologies in Brachytherapy provides readers with a wealth of relevant information needed to comprehend the rapidly advancing technologies and trends of today and the prospects for the future.

Strategies for Radiation Therapy Treatment Planning

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Author :
Publisher : Springer Publishing Company
ISBN 13 : 0826122671
Total Pages : 320 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Strategies for Radiation Therapy Treatment Planning by : Ping Xia, PhD

Download or read book Strategies for Radiation Therapy Treatment Planning written by Ping Xia, PhD and published by Springer Publishing Company. This book was released on 2018-10-28 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: “This is a high quality book with directions and guidelines on how to generate valid treatment plans in the modern era of radiation oncology. It is very useful for any student (dosimetry, therapy, physicist, or physician) who is entering a practical treatment planning rotation...It is written as a companion to the Handbook of Treatment Planning in Radiation Oncology, 2nd edition, Videtic et al. (Demos Medical Publishing, 2015), and pairs very well with it.” Score: 88, 3 Stars, Doody’s Medical Reviews “Comparing with earlier published books about radiotherapy treatment planning, which are prone to the pedagogical side as textbooks, this new book serves an unmet need as a pocket-sized book with details and up to date information for user’s quick resource for treatment planning knowledge... “Strategies for Radiation Therapy Treatment Planning” is a handy and essential reference for modern treatment planning. It is therefore recommended as a valuable book for the bookshelf and pocket of everyone involved in radiotherapy treatment planning.” -- Dr. Chengyu Shi of Memorial Sloan Kettering Cancer Center for Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. Strategies for Radiation Therapy Treatment Planning provides radiation oncologists, physicists, and dosimetrists with a step-by-step guide to implementing external beam treatment plans that meet clinical requirements for each major disease site. As a companion book to the Handbook of Treatment Planning in Radiation Oncology Second Edition, this book focuses on the technical aspects of treatment planning and the major challenges in creating highly conformal dose distributions, referenced to as treatment plans, for external beam radiotherapy. To overcome challenges associated with each step, leading experts at the Cleveland Clinic have consolidated their knowledge and experience of treatment planning techniques, potential pitfalls, and other difficulties to develop quality plans across the gamut of clinical scenarios in radiation therapy. The book begins with an overview of external beam treatment planning principles, inverse planning and advanced planning tools, and descriptions of all components in simulation and verification. Following these introductory chapters are disease-site examples, including central nervous system, head and neck, breast, thoracic, gastrointestinal, genitourinary, gynecologic, lymphoma, and soft tissue sarcoma. The book concludes with expert guidance on planning for pediatric cancers and how to tailor palliative plans. Essential for all radiation therapy team members, including trainees, this book is for those who wish to learn or improve their treatment planning skills and understand the different treatment planning processes, plan evaluation, and patient setup. KEY FEATURES: Provides basic principles of treatment planning Contains step-by-step, illustrated descriptions of the treatment planning process Discusses the pros and cons of advanced treatment planning tools, such as auto-planning, knowledge-based planning, and multi-criteria based planning Describes each primary treatment site from simulation, patient immobilization, and creation of various treatment plans to plan evaluations Includes instructive sample plans to highlight best practices

Brachytherapy Physics

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Author :
Publisher : Medical Physics Publishing Corporation
ISBN 13 : 9781930524248
Total Pages : 965 pages
Book Rating : 4.5/5 (242 download)

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Book Synopsis Brachytherapy Physics by : Bruce Thomadsen

Download or read book Brachytherapy Physics written by Bruce Thomadsen and published by Medical Physics Publishing Corporation. This book was released on 2005 with total page 965 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is organized into 6 sections: Fundamentals; Dosimetry; Interstitial Fundamentals; Interstitial Applications; Intercavitary Applications for Gynecological Cancer, and Unconventiional Delivery Systems. The book includes a CD-ROM containing an electronic version of the book (with many illustrations in full color) plus a compiled list of references.

Practical Radiation Oncology Physics E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323263755
Total Pages : 400 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Practical Radiation Oncology Physics E-Book by : Sonja Dieterich

Download or read book Practical Radiation Oncology Physics E-Book written by Sonja Dieterich and published by Elsevier Health Sciences. This book was released on 2015-06-24 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for radiation oncologists, medical physicists, and residents in both fields, Practical Radiation Oncology Physics provides a concise and practical summary of the current practice standards in therapeutic medical physics. A companion to the fourth edition of Clinical Radiation Oncology, by Drs. Leonard Gunderson and Joel Tepper, this indispensable guide helps you ensure a current, state-of-the art clinical practice. Covers key topics such as relative and in-vivo dosimetry, imaging and clinical imaging, stereotactic body radiation therapy, and brachytherapy. Describes technical aspects and patient-related aspects of current clinical practice. Offers key practice guideline recommendations from professional societies throughout — including AAPM, ASTRO, ABS, ACR, IAEA, and others. Includes therapeutic applications of x-rays, gamma rays, electron and charged particle beams, neutrons, and radiation from sealed radionuclide sources, plus the equipment associated with their production, use, measurement, and evaluation. Features a "For the Physician" box in each chapter, which summarizes the key points with the most impact on the quality and safety of patient care. Provides a user-friendly appendix with annotated compilations of all relevant recommendation documents. Medicine eBook is accessible on a variety of devices.