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Optimal Coupling Between The Left Ventricle And The Arterial System
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Book Synopsis Optimal Coupling Between the Left Ventricle and the Arterial System by : Gabriel Noachas Eisenberg
Download or read book Optimal Coupling Between the Left Ventricle and the Arterial System written by Gabriel Noachas Eisenberg and published by . This book was released on 1993 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Ventricular/Vascular Coupling by : Frank C.P. Yin
Download or read book Ventricular/Vascular Coupling written by Frank C.P. Yin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiologists have long been interested in the interaction, or coupling, between the heart and the vasculature. The early literature consists mainly of phenomenological descriptions of cardiac alterations resulting from specific interventions in the vasculature. Hundreds of studies, for example, describe functional aspects of hypertrophied myocardium associated with the excessive vascular loading produced by various types of experimental hypertension. Recently, the concepts of ventricular/vascular interaction have found important clinical application. The widespread use of vaso dilators and of intraaortic counterpUlsation balloons for unloading an ov erburdened, diseased heart is a prime example. Despite the interest in this field, until as recently as 20 years ago we were not able to describe ventricular or vascular function in a framework suitable for quantitatively expressing the interaction between these two complex systems. Three major developments-description of ventricular function in terms of both the time-varying elastance and the pump function graph and quantification of vascular function in terms of impedance have changed this. These functional descriptions now enable systems en gineers, bioengineers, physiologists, and clinicians to address very specific quantitative aspects of ventricular/vascular interaction and have resulted in a flurry of papers and symposia devoted to this subject.
Book Synopsis Ventricular Function by : David C. Warltier
Download or read book Ventricular Function written by David C. Warltier and published by Lippincott Williams & Wilkins. This book was released on 1995 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Coronary Blood Flow by : Michitoshi Inoue
Download or read book Regulation of Coronary Blood Flow written by Michitoshi Inoue and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Book Synopsis Regulation of Cardiac Contractility by : R. John Solaro
Download or read book Regulation of Cardiac Contractility written by R. John Solaro and published by Biota Publishing. This book was released on 2011-04-01 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contractility describes the relative ability of the heart to eject a stroke volume (SV) at a given prevailing afterload (arterial pressure) and preload (end-diastolic volume; EDV). Various measures of contractility are related to the fraction as the SV/EDV or the ejection fraction, and the dynamics of ejection as determined from maximum pressure rise in the ventricles or arteries or from aortic flow velocities determined by echocardiography. At the cellular level, the ultimate determinant of contractility is the relative tension generation and shortening capability of the molecular motors (myosin cross-bridges) of the sarcomeres as determined by the rates and extent of Ca activation, the turnover kinetics of the cross-bridges, and the relative Ca responsiveness of the sarcomeres. Engagement of the regulatory signaling cascades controlling contractility occurs with occupancy and signal transduction by receptors for neurohumors of the autonomic nervous system as well as growth and stress signaling pathways. Contractility is also determined by the prevailing conditions of pH, temperature, and redox state. Short-term control of contractility is fully expressed during exercise. In long-term responses to stresses on the heart, contractility is modified by cellular remodeling and altered signaling that may compensate for a time but which ultimately may fail, leading to disorders.
Book Synopsis Vascular Aging: Facts and Factors by : Elisabet Vila
Download or read book Vascular Aging: Facts and Factors written by Elisabet Vila and published by Frontiers E-books. This book was released on with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing mean age of the population in developed countries has turned out to be an economic and social problem. Cardiovascular disease has long been considered to be age related in terms of their onset and progression. As such, we can say that the increase in life expectancy goes in parallel with increased incidence of cardiovascular disease. With age, a number of changes occur in the vasculature altering the homeostasis of the irrigated organs promoting target organ damage. While different adaptive mechanisms to protect vessels against mild stress have been described, the aging process induces a progressive failure of protective mechanisms, leading to vascular changes and higher susceptibility to cardiovascular diseases. Indeed, vascular aging is exacerbated by coexisting cardiovascular risk factors, such as hypertension, metabolic syndrome and diabetes. Compelling evidence indicates that diminished endothelial relaxation and increase, decrease, or no change in contractile responses to several agonists is associated with aging. There is an increase of vasoconstrictor factors expression and a decrease of vasodilators. Morphologic changes include lumen diameter enlargement, wall thickening and alterations of matrix substances as increased collagen or decreased elastin deposition, ultimately leading to greater arterial stiffening (reduced compliance). Importantly, arterial stiffness is an independent predictor of cardiovascular morbidity and mortality. Cellular and molecular mechanisms have also been documented. Senescence at the cellular level involves alterations in Ca2+ signaling and down regulation of anti-aging proteins. Both endothelial and smooth muscle cells change their number, morphology, function and their regenerative ability. Aging is also associated with a gradual loss of antioxidant defense mechanisms, a proinflammatory shift in the cytokine expression profile and a production of reactive oxygen species such as superoxide (O2-) that promotes the breakdown of nitric oxide. Nitric oxide and O2- interact to form peroxynitrite known to nitrosylate proteins affecting their physiological function. However, vascular wall proteins may also suffer from other potentially deleterious modifications as glycation (Maillard reaction) and glyco-oxidative reactions with increasing age, which could be linked to the age-associated changes in vascular function. Various strategies have shown benefit in preventing, delaying or attenuating vascular aging. For instance, a healthy lifestyle including low fat diet and/or exercise have a favorable effect. Nevertheless, it yet remains to be fully demonstrated whether vascular aging can be pharmacologically prevented. This Research Topic is intended to bring together research efforts to understand the causes and consequences of vascular aging and propose new therapeutic strategies for the management of vascular senescence.
Book Synopsis Miller's Anesthesia by : Lars I. Eriksson
Download or read book Miller's Anesthesia written by Lars I. Eriksson and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 3221 pages. Available in PDF, EPUB and Kindle. Book excerpt: From fundamental principles to advanced subspecialty procedures, this text is the go-to reference on the technical, scientific, and clinical challenges professionals face. Features new chapters, new authors, meticulous updates, an increased international presence, and a new full-color design.
Book Synopsis Analysis and Simulation of the Cardiac System Ischemia by : Rafael Beyar
Download or read book Analysis and Simulation of the Cardiac System Ischemia written by Rafael Beyar and published by CRC Press. This book was released on 2020-10-28 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over thiry-five experts contribute to this publication about the various interactions and interrelationships of the parameters which affect the normal and ischemic heart. Mechanical aspects related to the global and regional function of the heart are discussed. Coronary perfusion of the ischemic heart is considered, with emphasis on the effects of reperfusion. Electrical activation, formation of arrhythmias, and the effects of ischemia or ionic transport in the myocardium are presented. Metabolic aspects of the ischemic heart, including calcium transport, are also explained.
Book Synopsis Heart Failure Mechanisms and Management by : Basil S. Lewis
Download or read book Heart Failure Mechanisms and Management written by Basil S. Lewis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following remarkable advances in medical care. the past decade has witnessed a significant improvement in the survival of patients with many different forms of heart disease. In the majority ofcases. however. the advances have been pa lIiative and not curative. The resu It has been the prod uction of an ever-increasing population of patients with heart disease. many of whom suffer from myocardial dysfunction and latent or overt heart failure. Heart failure is now a major cause of morbidity and mortality in cardiac patients. This book aims to combine in a single volume data relating to both pathophysiological mechanisms and the clinical management of the patient with heart failure. It includes chapters dealing with molecular. biochemical. and pathophysiological aspects of heart failure. ven tricular function and its assessment. and the clinical aspects of heart failure in different cardiac disorders, including ischemic heart disease. valvular heart disease. and the cardiomyopathies. There are sections on pharmacotherapy. the role of arrhythmias, exercise physiology. and neurohumoral mechanisms. The book also deals with newer inter ventional techniques. newer surgical procedures and some current problems relating to cardiac assist devices and heart and heart-lungs transplantation.
Book Synopsis Mathematical Modeling of Cardiovascular Systems: From Physiology to the Clinic by : Julius Guccione
Download or read book Mathematical Modeling of Cardiovascular Systems: From Physiology to the Clinic written by Julius Guccione and published by Frontiers Media SA. This book was released on 2020-01-13 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Recent Progress in Failing Heart Syndrome by : Shigetake Sasayama
Download or read book Recent Progress in Failing Heart Syndrome written by Shigetake Sasayama and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart failure is a syndrome caused by a heart dysfunction that leads to insuf ficient blood in the peripheral tissues for their metabolic demands. This syn drome still remains an obscure clinical entity and even its definition is disputed. It has become increasingly apparent that heart failure may relate not only to cardiac dysfunction but also to other physiological alterations involved in the maintenance of circulatory homeostasis. In 1988, the Japanese Circulation Society organized a three-year project for research on heart failure. The research group consisted of ten investigators, all relatively young but well recognized internationally for their research accomplishments. This book represents a compilation of the achievements by this group during the past three years which have led to new insights into the pathophysiologic mechanisms of heart failure, and diagnosis, evaluation and treatment of this syndrome. Contents include research into the cellular biology of congestive heart failure, and a framework of pressure-volume relationships enabling assessment of ventricular contraction energetics or coupling of ventricular properties and arterial load. This conceptual framework is of vital significance, particularly when we consider the failing heart as an energy-depleted state. An understanding of the neuroendocrine responses to explain the pathophy siology of congestive heart failure is perhaps the most important advance, and has led to new developments in therapy. This book also includes an analysis of mechanical factors, including both regional, and global ventricular functions, and this is related to the under standing of the pathophysiology of congestive heart failure.
Book Synopsis The Right Ventricle by : Marvin A. Konstam
Download or read book The Right Ventricle written by Marvin A. Konstam and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is quite natural that literature related to car heart disease, cardiomyopathy, pulmonary and diac structure, function, pathology, and patho pulmonary vascular disease, trauma, acquired valvular disease, congenital disease, and surgi physiology has emphasized the left heart and systemic circulation. The relative lack of im cal considerations. The pathologic and clinical relevance of myocardial infarction of the right portance of the right ventricle was supported by studies performed in the 1940s and 1950s ventricle has only been documented over the which suggested that the right ventricular free last 15 years. The chapter on right ventricular wall could be effectively destroyed in an animal infarction integrates clinical, functional, patho model without detectable untoward hemody physiologic, and pathologic observations to pro namic consequences. The relative inadequacy vide the reader with a thorough review, equally of noninvasive tools to study right ventricular relevant to the clinician and investigator. The contribution on dilated cardiomyopathy pro structure and function obviated detailed and systematic investigation. However, over the vides novel insight into the impact of right ventricular performance on the functional in past 15 years there has been a resurgence of interest in the right ventricle by a variety of capacity accompanying left heart failure. A book dealing with the right ventricle would investigators. The skeptic would argue that this renewed interest resulted from an exhaustion be incomplete without at least cursory reference we have of clinically-related observations that could be to the pulmonary circulation.
Book Synopsis Cardiovascular Emergencies, Part II, An Issue of Heart Failure Clinics by : Giovanni Esposito
Download or read book Cardiovascular Emergencies, Part II, An Issue of Heart Failure Clinics written by Giovanni Esposito and published by Elsevier Health Sciences. This book was released on 2020-07-16 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Heart Failure Clinics, guest edited by Giovanni Esposito and Michinari Hieda, will cover key topics in Cardiovascular Emergencies. This is part two of a two-part issue and is one of four issues selected each year by our series consulting editor, Dr. Eduardo Bossone. Topics discussed in this issue will include: Case Report in the ER, Cardiac Energetics in Patients with Acute Myocardial Infarction, Cardiac Emergency in Patients with Left Ventricular Assist Devices or Heart Transplantation, Cardiac Emergency in Patients just before Going to Left Ventricular Assist Device, Cardiac Emergency in Patients with Left Ventricular Assist Devices, Acute Aortic Syndrome, Multimodality Imaging in Cardiovascular Emergencies, Biomarkers in the Emergency Room, Acute Pulmonary Embolism, and Obesity Patient with Heart Failure.
Book Synopsis Annual Update in Intensive Care and Emergency Medicine 2013 by : Jean-Louis Vincent
Download or read book Annual Update in Intensive Care and Emergency Medicine 2013 written by Jean-Louis Vincent and published by Springer Science & Business Media. This book was released on 2013-04-08 with total page 862 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Yearbook compiles the most recent developments in experimental andclinical research and practice in one comprehensive reference book. Thechapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Book Synopsis Echocardiography for Intensivists by : Armando Sarti
Download or read book Echocardiography for Intensivists written by Armando Sarti and published by Springer Science & Business Media. This book was released on 2012-12-18 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains all the information that readers will require in order to perform echocardiography and to interpret the findings correctly. After an introductory chapter on the essential physics of ultrasonography, standard echocardiographic examination via both the transthoracic and the transesophageal approach is described. In the third section, the functional anatomy of all normal and pathologic thoracic structures as observed on echocardiography is presented in detail. A wide range of basic and advanced applications of echocardiography in the emergency and intensive care setting are then described. A final supplementary section considers further applications of ultrasound in the intensive care unit. This superbly illustrated book has been specifically designed to meet the needs of all intensivists, emergency physicians, and anesthesiologists who intend to use ultrasound extensively to guide optimal management of the critically ill.
Book Synopsis Clinical Calculations - E-Book by : Joyce LeFever Kee
Download or read book Clinical Calculations - E-Book written by Joyce LeFever Kee and published by Elsevier Health Sciences. This book was released on 2020-06-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to calculate drug dosages safely, accurately, and easily with Kee’s Clinical Calculations, 9th Edition! This market-leading text covers all four major drug calculation methods, including ratio & proportion, formula, fractional equation, and dimensional analysis. It also includes practice problems for both general care as well as specialty areas such as pediatrics, labor and delivery, critical care, and community nursing. With its market-leading, comprehensive coverage; strong emphasis on patient safety; and the incorporation of the latest information on antidiabetic agents, anticoagulant agents, drug administration techniques, and devices; Kee remains the winning choice for easy drug calculation mastery. Coverage of all four major drug calculation methods includes ratio & proportion, formula, fractional equation, and dimensional analysis to help you learn and apply the method that works best for you. The latest information on drug administration techniques and devices helps you master the most up-to-date techniques of drug administration, including oral, intravenous, intra-muscular, subcutaneous, and other routes. Caution boxes provide alerts to problems or issues related to various drugs and their administration. Information on infusion pumps covers enteral, single, multi-channel, PCA, and insulin; and explains their use in drug administration. Calculations for Specialty Areas section addresses the drug calculations needed to practice in pediatric, critical care, labor and delivery, and community settings. Detailed, full-color photos and illustrations show the most current equipment for IV therapy, the latest types of pumps, and the newest syringes. Comprehensive post-test lets you test your knowledge of key concepts from the text. NEW! Updated information on Antidiabetic Agents (orals and injectables) has been added throughout the text where appropriate. NEW! Updated content on Anticoagulant Agents is housed in an all-new chapter. NEW! Colorized abbreviations for the four methods of calculation (BF, RP, FE, and DA) appear in the Example Problems sections. NEW! Updated content and patient safety guidelines throughout the text reflects the latest practices and procedures. NEW! Updated practice problems across the text incorporate the latest drugs and dosages.
Book Synopsis Hemodynamic Physiology in Advanced Heart Failure and Cardiogenic Shock by : Hoong Sern Lim
Download or read book Hemodynamic Physiology in Advanced Heart Failure and Cardiogenic Shock written by Hoong Sern Lim and published by Springer Nature. This book was released on with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: