OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319B: Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub-cellular fraction (RT-S9)

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Publisher : OECD Publishing
ISBN 13 : 9264303235
Total Pages : 36 pages
Book Rating : 4.2/5 (643 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319B: Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub-cellular fraction (RT-S9) by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319B: Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub-cellular fraction (RT-S9) written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...

OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP)

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Publisher : OECD Publishing
ISBN 13 : 9264303219
Total Pages : 41 pages
Book Rating : 4.2/5 (643 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP) by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 319A: Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes (RT-HEP) written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...

Toxicology of Fishes

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Publisher : CRC Press
ISBN 13 : 1003825265
Total Pages : 1118 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Toxicology of Fishes by : Kristine L. Willett

Download or read book Toxicology of Fishes written by Kristine L. Willett and published by CRC Press. This book was released on 2024-02-06 with total page 1118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, comprehensive toxicology handbook is devoted to the effects of environmental pollution on fish. Fish species represent nearly half of all vertebrates and have become important sentinels for environmental contamination and model organisms for understanding adverse outcomes from exposures. This new edition is written by recognized experts, and it highlights the significant research progress in fish toxicology that has resulted from rapid technological developments in analytical, biochemical, and genomic sciences. The book: Discusses fundamental topics such as toxicokinetics in fishes, processes governing biotransformation within these organisms, and reactive oxygen species and oxidative stress. Explains key target organ systems for chemical impacts in fish, such as the nervous and immune systems, and how fishes can develop resistance to chemical toxicity. Covers multi-transgenerational effects on fishes, epigenetics, proteomics and metabolomics, and adverse outcome pathways. Replacing the case studies in the first edition, this update delves into the impacts of microplastics, pharmaceuticals, and oil spills in dedicated final chapters. With nearly 200 illustrations and tables, this comprehensive reference work presents concepts in a way that is useful for both novices to and experts in the field of fish toxicology.

Ecotoxicology of Nanoparticles in Aquatic Systems

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Publisher : CRC Press
ISBN 13 : 1351657542
Total Pages : 273 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Ecotoxicology of Nanoparticles in Aquatic Systems by : Julian Blasco

Download or read book Ecotoxicology of Nanoparticles in Aquatic Systems written by Julian Blasco and published by CRC Press. This book was released on 2019-07-19 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with new global scenarios. The book also covers the bioaccumulation and internalization of nanoparticles as key aspects to assess their uptake and discusses the methodologies for testing ENPs ecotoxicity at different trophic levels.

Human and Ecological Risk Assessment

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Publisher : John Wiley & Sons
ISBN 13 : 111974296X
Total Pages : 1319 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Human and Ecological Risk Assessment by : Dennis J. Paustenbach

Download or read book Human and Ecological Risk Assessment written by Dennis J. Paustenbach and published by John Wiley & Sons. This book was released on 2024-04-15 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.

OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 312: Leaching in Soil Columns

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Author :
Publisher : OECD Publishing
ISBN 13 : 9264070567
Total Pages : 15 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 312: Leaching in Soil Columns by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 312: Leaching in Soil Columns written by OECD and published by OECD Publishing. This book was released on 2004-11-23 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt: The method described in this Test Guideline is based on soil column chromatography in disturbed soil. Two types of experiments are performed to determine (i) the leaching potential of the test substance, and (ii) the leaching potential of ...

Xenobiotics in Fish

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Publisher : Springer Science & Business Media
ISBN 13 : 1461547032
Total Pages : 226 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Xenobiotics in Fish by : D.J. Smith

Download or read book Xenobiotics in Fish written by D.J. Smith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aquaculture is rapidly becoming a major source of fish protein used to meet the nutritional needs of humans. As the aquaculture industry grows, exposure of farmed fish to environmental contaminants, and the need for chemical therapeutic agents for fish, will increase. This book is designed to bring together authorities worldwide on the regulation of environmental contaminants and food chemicals and researchers investigating the metabolism and disposition of foreign chemicals (xenobiotics) in fish species.

The Toxicology of Fishes

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Publisher : CRC Press
ISBN 13 : 0203647297
Total Pages : 1102 pages
Book Rating : 4.2/5 (36 download)

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Book Synopsis The Toxicology of Fishes by : Richard T. Di Giulio

Download or read book The Toxicology of Fishes written by Richard T. Di Giulio and published by CRC Press. This book was released on 2008-02-25 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: When looking for a book on fish toxicology, you might find one that discusses the biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You can find resources that cover human and animal toxicology or ecotoxicology in general, but no up-to-date, comprehensive monograph devoted to the effects of chemical pollution on

Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment

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Publisher : CRC Press
ISBN 13 : 9780849368448
Total Pages : 360 pages
Book Rating : 4.3/5 (684 download)

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Book Synopsis Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment by : Usha Varanasi

Download or read book Metabolism of Polycyclic Aromatic Hydrocarbons in the Aquatic Environment written by Usha Varanasi and published by CRC Press. This book was released on 1989-03-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book shows how the biological transport, bioaccumulation, disposition, and toxicity of polycyclic aromatic hydrocarbons (PAH) in the aquatic environment are influenced by the ability or inability of organisms to metabolize these environmental pollutants. Written by leading scientists in the fields of PAH metabolism and toxicity in both aquatic and mammalian systems, this book discusses recent advances in the areas of PAH biogeochemistry and bioaccumulation, microbial degradation, enzymes of activation, and detoxication, metabolism of PAH, and laboratory and field studies on carcinogenic/toxic effects. Additionally, important similarities and differences in metabolism of PAH by aquatic and terrestrial organisms are featured. The discussion of bioavailability, metabolism, and subsequent toxic effects should aid in the assessment of the ecological consequences of PAH in the aquatic environment.

OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 317: Bioaccumulation in Terrestrial Oligochaetes

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Publisher : OECD Publishing
ISBN 13 : 9264090932
Total Pages : 30 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 317: Bioaccumulation in Terrestrial Oligochaetes by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 3 Test No. 317: Bioaccumulation in Terrestrial Oligochaetes written by OECD and published by OECD Publishing. This book was released on 2010-07-23 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes procedures designed to assess bioaccumulation of chemicals in soil oligochaetes. The parameters which characterise the bioaccumulation of a substance include the bioaccumulation factor (BAF), the uptake rate constant ...

Toxicity Testing in the 21st Century

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Publisher : National Academies Press
ISBN 13 : 0309109922
Total Pages : 217 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicity Testing in the 21st Century by : National Research Council

Download or read book Toxicity Testing in the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2007-10-05 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Endocrine Disrupters

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Publisher : John Wiley & Sons
ISBN 13 : 0470932090
Total Pages : 0 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Endocrine Disrupters by : Peter Matthiessen

Download or read book Endocrine Disrupters written by Peter Matthiessen and published by John Wiley & Sons. This book was released on 2013-03-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals—both man-made and natural—that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including: Crustaceans and mollusks Insects Fish Amphibians and reptiles Birds and mammals Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.

Anticoagulant Rodenticides and Wildlife

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Publisher : Springer
ISBN 13 : 3319643770
Total Pages : 408 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Anticoagulant Rodenticides and Wildlife by : Nico W. van den Brink

Download or read book Anticoagulant Rodenticides and Wildlife written by Nico W. van den Brink and published by Springer. This book was released on 2017-11-09 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Commensal rodents pose health risks and cause substantial damage to property and food supplies. Rats have also invaded islands and pose a serious threat to native wildlife, particularly raptors and seabirds. Estimates of total damage from introduced rats range into the billions of dollars in developed countries. This book aims to provide a state-of-the-art overview of the scientific advancements in the assessment of exposure, effects and risks that currently used rodenticides may pose to non-target organisms in the environment, along with practical guidance for characterization of hazards. This will be discussed in relation to their efficacy, and the societal needs for rodent control, and discussion of risk mitigation and development of alternatives. The flow in the book is planned as: a. introduction and setting the scene b. problem description (risks and effects on non-targets and secondary poisoning, development of resistance) c. ; alternatives, regulation and risk mitigation d. conclusions and recommendations

Treatment of Hypertension with Urapidil

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Publisher :
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Treatment of Hypertension with Urapidil by : Anthony Amery

Download or read book Treatment of Hypertension with Urapidil written by Anthony Amery and published by . This book was released on 1986 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fish Physiology: The Multifunctional Gut of Fish

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Publisher : Academic Press
ISBN 13 : 0080961363
Total Pages : 472 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Fish Physiology: The Multifunctional Gut of Fish by :

Download or read book Fish Physiology: The Multifunctional Gut of Fish written by and published by Academic Press. This book was released on 2010-10-21 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Multifunctional Gut of Fish provides a comprehensive synthesis and an integrative overview of the range of gut functions and their implications for organismal physiology. The highly diversified anatomy and functions of the gut, including nutrient uptake, immune barrier function, salt and water homeostasis and respiration, as well as neuroendocrine actions and control are covered in detail by leading authors. In addition, this volume explores the pronounced implications of gut function for whole animal integrative physiology and compensatory demands for non-gastrointestinal organs. As the first comprehensive reference to discuss the diverse morphological and functional adaptations of the gut, this volume provides an excellent resource for comparative physiologists, aquaculturists and biomedical researchers employing fish as model organisms for mammalian physiology. - Includes chapters dedicated to anatomical and functional features of the gastro-intestinal tract of fish as well as integrative aspects of gut organ function - Includes in depth coverage of recently recognized implications of feeding on salt homeostasis and acid-base balance - Provides syntheses of implications of gut function for homeostasis - Essential text for those interested in the wide diversity of functions performed by the gut

Enzyme Kinetics

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Publisher : John Wiley & Sons
ISBN 13 : 3527806474
Total Pages : 340 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Enzyme Kinetics by : Hans Bisswanger

Download or read book Enzyme Kinetics written by Hans Bisswanger and published by John Wiley & Sons. This book was released on 2017-06-22 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in full color for a more intuitive learning experience, this new edition of the long-selling reference also features a number of new developments in methodology and the application of enzyme kinetics. Starting with a description of ligand binding equilibria, the experienced author goes on to discuss simple and complex enzyme reactions in kinetic terms. Special cases such as membrane-bound and immobilized enzymes are considered, as is the influence of external conditions, such as temperature and pH value. The final part of the book then covers a range of widely used measurement methods and compares their performance and scope of application. With its unique mix of theory and practical advice, this is an invaluable aid for teaching as well as for experimental work.

Nutrient Requirements and Feeding of Finfish for Aquaculture

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Author :
Publisher : CABI
ISBN 13 : 9780851997025
Total Pages : 440 pages
Book Rating : 4.9/5 (97 download)

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Book Synopsis Nutrient Requirements and Feeding of Finfish for Aquaculture by : Carl D. Webster

Download or read book Nutrient Requirements and Feeding of Finfish for Aquaculture written by Carl D. Webster and published by CABI. This book was released on 2002-02-01 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Good nutrition is fundamental to the success and sustainability of the aquaculture industry in terms of economics, fish health, high quality product production and minimizing environmental pollution. This book provides a unique, complete coverage of current information on nutrientrequirements, feed formulations and feeding practices of commercially important aquaculture species cultured around the world. Each chapter contains detailed feeding information on specific species and is written by an expert nutritionist on that species. The book is of interest to those workingprofessionally in the industry, graduate level students and researchers.