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Author : Kevin Daniel Lau
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (116 download)
Download or read book Numerical Simulation of Mitral Valve Function written by Kevin Daniel Lau and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : K. D. Lau
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (829 download)
Download or read book Numerical Simulation of Mitral Valve Function written by K. D. Lau and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In the mammalian heart there are four heart valves (HV), of which the largest is the mitral valve (MV). Key components in the circulatory system, correct HV function is vital to cardiovascular health. A tethered and asymmetric structure, the MV regulates unidirectional flow between the left atrium and left ventricle. MVfunction is divided between systole/closure, where theMVis required to sustain a pressure load ~120 mmHg whilst minimising flow reversal, and diastole/opening in which the MV is required to rapidly transition from closed to open in order to maximise the transport of blood. Directly affecting the heart, dysfunction of the MV can affect either opening or closing through stenoses or prolapse/regurgitation respectively. Complementing experimental techniques, numerical simulation of theMVoffers additional insights into MV function as unmeasurable variables such as the stresses can be approximated. Due to the immersed nature of the HVs, numerical simulation of the MV requires an approach that is able to model both the large deformation of the MV and non-uniform haemodynamics pressure load resulting from the blood/HV contact. In this work the finite element solver LS-DYNA has been used as it addresses both issues. Using this framework, anatomically sized MV models have been used to characterise the current methodology of reported HV simulations, showing that the fluid-structure interaction (FSI) modelling of the blood/HV contact is essential in the simulation of MV dynamics. Application of this FSI method has been applied to surgical repair technique of the MV known as the edge-to-edge repair, showing that more invasive procedures result in greater stress concentrations but impaired the flow rates. Further advances in this model have been used to examine growth and remodelling effect of the MV tissue in both normal and dysfunctional states.
Author : Alireza Nejadmalayeri
Publisher :
ISBN 13 :
Total Pages : 162 pages
Book Rating : 4.:/5 (259 download)
Download or read book Numerical Simulation of Pulsatile Blood Flow Across a Tilting-disk Mechanical Heart Valve written by Alireza Nejadmalayeri and published by . This book was released on 2007 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: To overcome several clinical challenges involving mechanical heart valves, accurate numerical simulation of blood flow through these devices has been of interest. Since heart disease is the leading cause of death around the world, the hemodynamic study of the heart is of extraordinary interest in the field of bio fluid dynamics. Recent numerical/experimental investigations have shown that mechanical heart valves inherit the "production of sufficiently large shear and turbulent stresses to cause clinical problems such as hemolysis." Due to several parameters including the non-Newtonian behavior of blood, pulsatile waveform, strong blood and tissue interactions, clinical difficulties, etc., experimental examination of blood flow in the heart and its valves is a very difficult task. Therefore, comprehensive numerical analysis of this complex fluid-structure system is essential. However, precise experimental investigations are still imperative for developing appropriate and accurate turbulence models and for validating numerical techniques.In the current computational effort, the first set of objectives was numerical investigations of vortex shedding behind a two-dimensional tilting-disk mechanical heart valve in a straight channel, which is a simplified representation of the mitral position, using first- and several higher-order finite volume schemes as well as examination of the non-Newtonian viscosity effects on shedding frequency and amplitude.
Author : Daniele Boffi
Publisher : Springer
ISBN 13 : 3319966499
Total Pages : 243 pages
Book Rating : 4.3/5 (199 download)
Download or read book Mathematical and Numerical Modeling of the Cardiovascular System and Applications written by Daniele Boffi and published by Springer. This book was released on 2018-11-03 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range of topics, from the assimilation of clinical data to the development of mathematical and computational models, including with parameters, as well as their efficient numerical solution, and both in-vivo and in-vitro validation. It also considers applications of relevant clinical interest. This book is intended for graduate students and researchers in the field of bioengineering, applied mathematics, computer, computational and data science, and medicine wishing to become involved in the highly fascinating task of modeling the cardiovascular system.
Author : Lee Xin Leong
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783659218507
Total Pages : 168 pages
Book Rating : 4.2/5 (185 download)
Download or read book Numerical Analysis on Simplified 2D Model of Heart Valve written by Lee Xin Leong and published by LAP Lambert Academic Publishing. This book was released on 2012 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, the increasing numbers of heart diseases cases is very worrying although the medication technologies are always improving and moving forward.In this book, numerical modeling was used to study the effect of blood flow velocity and leaflet displacement by different shape of simplified 2D model of heart valve leaflets during cardiac cycle.Five different shapes of mitral valve leaflets and aortic valve leaflets were created and the simulation was performed by using ADINA-Fluid Structure Interaction (FSI). Ellipse shape of leaflets could be chosen as the most suitable shape among these five shapes in further study of heart valve simulati
Author : Xueyan Yun
Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (485 download)
Download or read book Numerical Simulation of Coupled Fluid and Solid Motions in a Leaflet Type Artificial Heart Valve written by Xueyan Yun and published by . This book was released on 2000 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ardavan Aliabadi
Publisher :
ISBN 13 :
Total Pages : 81 pages
Book Rating : 4.:/5 (864 download)
Download or read book Numerical Simulation of Fluid-structure Interaction for Tilting-disk Mechanical Heart Valves written by Ardavan Aliabadi and published by . This book was released on 2013 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the United States Department of Health and Human Services, 27.1 million non-institutionalized adults were diagnosed with heart disease in 2010. The number of deaths associated with heart disease in 2009 was reported to be 599,413, claiming the lives of 195 out of every 100,000 people, which makes heart disease the number one killer in the U.S. Even though mechanical heart valves (MHVs) have proven to save lives in many of these cases, they are still not perfect, and complications arising from their design have reduced their application. To better understand the important factors and pursue remedies, numerous experimental investigations have been conducted; however, despite impressive improvements, small-scale studies suffer from lower levels of accuracy and sometimes are very costly to conduct. As in many other areas of research, numerical simulations can be helpful in reducing costs and supplementing such experimental work. The computational effort in this thesis focused on the numerical analysis of current tilting-disk MHVs. In this work, an implicit fluid-structure interaction (FSI) simulation of the Bjork-Shiley design was carried out using in-house codes implemented in the commercial code software FLUENT. In-house codes in the form of journal files, schemes, and user-defined functions (UDFs) were integrated to automate the inner iterations and enable communication between the fluid and the moving disk at the interfaces. Based on the investigation of the current simulations, a new design aiming at improving the hemodynamic performance is suggested. The hemodynamics of flow in current tilting-disk valves was compared with the suggested design, and it is concluded that the suggested design has a better hemodynamic performance in terms of shear stress values and residence times.
Author : Omid Sirous
Publisher :
ISBN 13 :
Total Pages : 128 pages
Book Rating : 4.:/5 (14 download)
Download or read book Numerical Simulation of the Leaflet Designs to Improve Hemodynamics of Mechanical Heart Valves written by Omid Sirous and published by . This book was released on 2017 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanical heart valves (MHVs) are widely implanted due to their reliability and long life span. However, patients who receive MHV implants are required and prescribed anticoagulant medication to reduce the high risk of thromboembolic complications. Although MHVs are considered as a long-term devices to save the lives of thousands of patients suffering from severe heart valve diseases, current designs could be improved based on the fundamentals of fluid mechanics in order to overcome some of the serious complications that can threaten the lives of patients, as well as improve the quality of their lives. Non-physiological blood flow and a higher level of mechanical stresses endured by the blood cells are considered as possible elements of those complications. It is believed that due to the non-physiological blood flow field through the MHVs, leaflet(s) motion can induce thromboembolism and also embolic strokes. The influence of higher levels of mechanical shear stresses, exposure time, and static flow zones behind the leaflet(s) cause significant effects to elevate platelet activation and thromboembolism formation. This research is an effort to provide further information regarding the capability of the passive flow management techniques to reduce these complications, and therefore improve the hemodynamic characteristics of blood flow to prevent high shear stress zones and blood cell damage. The objective of the current research activities is an attempt to examine pulsatile blood flow through MHVs with modified designs. In this investigation, we aim to investigate the effect of the valves with porous leaflets and compare the proposed design with the basic leaflet design. A set of steady and transient 3-dimensional models of MHVs with pulsatile, non-Newtonian turbulent blood flow were developed and investigated in order to: (1) numerically analyze the result of passive flow control techniques, (2) improve the hemodynamics of the valve, and (3) reduce the excessive levels of mechanical stresses compared to the basic bileaflet MHV. The computational models show a distinct difference in the flow field in the two designs, both of which demonstrate significant improvements in the hemodynamics of MHV.
Author : Kendra Stafford
Publisher :
ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.:/5 (152 download)
Download or read book Numerical Modeling of the Mitral Valve to Show Mitral Stenosis and Mitral Regurgitation written by Kendra Stafford and published by . This book was released on 2007 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kamalasrinny Radhakrisnnan
Publisher :
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4.:/5 (958 download)
Download or read book Numerical Simulation of Bileaflet Heart Valve Prostheses in Aortic Position written by Kamalasrinny Radhakrisnnan and published by . This book was released on 2012 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Arash Kheradvar
Publisher : Academic Press
ISBN 13 : 0128146621
Total Pages : 414 pages
Book Rating : 4.1/5 (281 download)
Download or read book Principles of Heart Valve Engineering written by Arash Kheradvar and published by Academic Press. This book was released on 2019-08-28 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts. Covers the depth and breadth of this interdisciplinary area of research Encompasses a wide range of topics, from basic science, to the translational applications of heart valve engineering Contains contributions from leading experts in the field that are heavily illustrated
Author : Amal M. Ahmed Owida
Publisher :
ISBN 13 :
Total Pages : 137 pages
Book Rating : 4.:/5 (225 download)
Download or read book Numerical Simulation and Experimental Validation of the Turbulent Flow Field Distal to an Aortic Heart Valve written by Amal M. Ahmed Owida and published by . This book was released on 2000 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xin Leong Lee
Publisher :
ISBN 13 :
Total Pages : 138 pages
Book Rating : 4.:/5 (953 download)
Download or read book Numerical Analysis on Simplified 2d Model of Heart Valve Leaflets During Cardiac Cycle written by Xin Leong Lee and published by . This book was released on 2012 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, the increasing numbers of heart diseases cases is very worrying although the medication technologies are always improving and moving forward. In this study, the objectives are to investigate the effect of blood flow velocity and leaflet displacement by using different shape of simplified two dimensional heart valve leaflets in the diastolic and systolic condition. Five different shapes of mitral valve leaflets and aortic valve leaflets were created and the simulation was performed by using ADINA-Fluid Structure Interaction. From the result obtained, triangle shape of leaflet showed it had the highest of blood velocity changes and leaflets displacement changes in a period time of one second when compare to the other four shapes whereas the square shape had the lowest performances. The relationship obtained for blood velocity flow and leaflet's displacement changes is same for both mitral valve and aortic valve. The velocity of flow and leaflet's displacement changes for triangle shape in diastolic condition is 68.54 mm/s and 2.171 mm while at systolic condition is 102 mm/s and 5.168 mm respectively for mitral valve. The outcome simulation result shows that large vortex formed behind the leaflet and leaflet deformed when the blood flow into left ventricle is agreed with the result in literature. In conclusion, five different shapes two-dimensional model of mitral valve and aortic valve has been developed and ellipse shape of valve leaflets is predicted to be the most suitable shape in applying for future artificial valve designing due to its good blood velocity flow with the small changes of leaflets displacement. Ellipse shape of leaflets could be chosen as the most suitable shape among these five shapes in further study of heart valve simulation.
Author : Mohd Azrul Hisham Mohd Adib
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783847372721
Total Pages : 76 pages
Book Rating : 4.3/5 (727 download)
Download or read book Blood Flow Into the Main Artery Via Mitral Valve written by Mohd Azrul Hisham Mohd Adib and published by LAP Lambert Academic Publishing. This book was released on 2012 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitral Valve failure causes death if it is not corrected surgically. Such surgical repair can be improved by understanding mitral biomechanics. A two-dimensional FSI model of the Mitral Valve was generated using the ADINA simulation. A simple approximation of the heart geometry was use, the valve dimensions were based on measurements made. The viscosity of blood and the elastic properties of the valve leaflets were obtained from the literature. In this book, numerical modeling was used to determine the correlation between the degeneration of the Mitral Valves rigidity and backflow problem based on several critical parameters of blood. Two stages of Mitral Valve simulation, systolic and diastolic stage and also with ventricle and without ventricle are investigated.
Author :
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.:/5 (317 download)
Download or read book Numerical Simulation of Flow Through an Artificial Heart written by and published by . This book was released on 1989 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Marco Evangelos Biancolini
Publisher : Springer
ISBN 13 : 3319750119
Total Pages : 366 pages
Book Rating : 4.3/5 (197 download)
Download or read book Fast Radial Basis Functions for Engineering Applications written by Marco Evangelos Biancolini and published by Springer. This book was released on 2018-03-29 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the first “How To” guide to the use of radial basis functions (RBF). It provides a clear vision of their potential, an overview of ready-for-use computational tools and precise guidelines to implement new engineering applications of RBF. Radial basis functions (RBF) are a mathematical tool mature enough for useful engineering applications. Their mathematical foundation is well established and the tool has proven to be effective in many fields, as the mathematical framework can be adapted in several ways. A candidate application can be faced considering the features of RBF: multidimensional space (including 2D and 3D), numerous radial functions available, global and compact support, interpolation/regression. This great flexibility makes RBF attractive – and their great potential has only been partially discovered. This is because of the difficulty in taking a first step toward RBF as they are not commonly part of engineers’ cultural background, but also due to the numerical complexity of RBF problems that scales up very quickly with the number of RBF centers. Fast RBF algorithms are available to alleviate this and high-performance computing (HPC) can provide further aid. Nevertheless, a consolidated tradition in using RBF in engineering applications is still missing and the beginner can be confused by the literature, which in many cases is presented with language and symbolisms familiar to mathematicians but which can be cryptic for engineers. The book is divided in two main sections. The first covers the foundations of RBF, the tools available for their quick implementation and guidelines for facing new challenges; the second part is a collection of practical RBF applications in engineering, covering several topics, including response surface interpolation in n-dimensional spaces, mapping of magnetic loads, mapping of pressure loads, up-scaling of flow fields, stress/strain analysis by experimental displacement fields, implicit surfaces, mesh to cad deformation, mesh morphing for crack propagation in 3D, ice and snow accretion using computational fluid dynamics (CFD) data, shape optimization for external aerodynamics, and use of adjoint data for surface sculpting. For each application, the complete path is clearly and consistently exposed using the systematic approach defined in the first section.
Author : Krishnan B. Chandran
Publisher : Springer Science & Business Media
ISBN 13 : 1441973508
Total Pages : 474 pages
Book Rating : 4.4/5 (419 download)
Download or read book Image-Based Computational Modeling of the Human Circulatory and Pulmonary Systems written by Krishnan B. Chandran and published by Springer Science & Business Media. This book was released on 2010-11-18 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Image-Based Computational Modeling of the Human Circulatory and Pulmonary Systems provides an overview of the current modeling methods and applications enhancing interventional treatments and computer-aided surgery. A detailed description of the techniques behind image acquisition, processing and three-dimensional reconstruction are included. Techniques for the computational simulation of solid and fluid mechanics and structure interaction are also discussed, in addition to various cardiovascular and pulmonary applications. Engineers and researchers involved with image processing and computational modeling of human organ systems will find this a valuable reference.
