Nuclear Medicine In Pharmaceutical Research

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Advancing Nuclear Medicine Through Innovation

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Radiopharmaceutical Chemistry

Author : Jason S. Lewis
Publisher : Springer
ISBN 13 : 3319989472
Total Pages : 648 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Radiopharmaceutical Chemistry by : Jason S. Lewis

Download or read book Radiopharmaceutical Chemistry written by Jason S. Lewis and published by Springer. This book was released on 2019-04-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Fundamentals of Nuclear Pharmacy

Author : Gopal B. Saha
Publisher : Springer
ISBN 13 : 3319575805
Total Pages : 430 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Fundamentals of Nuclear Pharmacy by : Gopal B. Saha

Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer. This book was released on 2017-11-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Nuclear Pharmacy

Author : Blaine T. Smith
Publisher :
ISBN 13 : 9780853698661
Total Pages : 0 pages
Book Rating : 4.6/5 (986 download)

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Book Synopsis Nuclear Pharmacy by : Blaine T. Smith

Download or read book Nuclear Pharmacy written by Blaine T. Smith and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This innovative textbook offers a comprehensive introduction to nuclear medicine with focus on the application of basic information. Nuclear Pharmacy will appeal to those wanting an accessible introduction to the topic, as well as those who would want to use it as a reference. Essential information on nuclear pharmacy is discussed, covering* introduction to basic nuclear physics * radioactive decay* radiopharmaceuticals* practice of nuclear pharmacy* methods for acquiring and using radiopharmaceuticals in the nuclear medicine department. Nuclear Pharmacy will be an invaluable resource for any pharmacy student, pharmacist, physician, nuclear pharmacy technician, radiology resident, and anyone seeking to explore and understand this fascinating field. Blaine Templar Smith is Chair at the Department of Pharmaceutical Sciences, Saint Joseph College School of Pharmacy,USA.

Technetium-99m Pharmaceuticals

Author : Ilse Zolle
Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle

Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

Handbook of Radiopharmaceuticals

Author : Michael R. Kilbourn
Publisher : John Wiley & Sons
ISBN 13 : 1119500540
Total Pages : 768 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Handbook of Radiopharmaceuticals by : Michael R. Kilbourn

Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.

Nuclear Medicine in Pharmaceutical Research

Author : M. Frier
Publisher : CRC Press
ISBN 13 : 1482272989
Total Pages : 201 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Nuclear Medicine in Pharmaceutical Research by : M. Frier

Download or read book Nuclear Medicine in Pharmaceutical Research written by M. Frier and published by CRC Press. This book was released on 2002-04-12 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text defines the role and scope of nuclear medicine imaging techniques (gamma scintigraphy) in pharmaceutical research, giving information from clinical trial data.

Therapeutic Nuclear Medicine

Author : Richard P. Baum
Publisher : Springer
ISBN 13 : 3540367195
Total Pages : 922 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Therapeutic Nuclear Medicine by : Richard P. Baum

Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.

A History of Radionuclide Studies in the UK

Author : Ralph McCready
Publisher : Springer
ISBN 13 : 9783319286235
Total Pages : 0 pages
Book Rating : 4.2/5 (862 download)

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Book Synopsis A History of Radionuclide Studies in the UK by : Ralph McCready

Download or read book A History of Radionuclide Studies in the UK written by Ralph McCready and published by Springer. This book was released on 2016-03-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The British Nuclear Medicine Society celebrates its 50th Anniversary with this booklet, which reflects the research of many of the pioneers in the use of radionuclides for the diagnosis and therapy of human disease. Since 1949 there have been remarkable advances in radionuclide techniques and imaging equipment: from the first devices “home-made” in the many physics departments throughout the UK, to the sophisticated multimodality imagers now in everyday use in Nuclear Medicine. The BNMS has been instrumental in promoting the use of radionuclide techniques in the investigation of pathology by supporting and providing education, research and guidelines on the optimum use of radiation to help patients. The future of Nuclear Medicine is bright, thanks to improved imaging resolution, new radiopharmaceuticals, and new diagnostic and therapeutic techniques and procedures.

Targeted Radionuclide Therapy

Author : Tod W. Speer
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451153260
Total Pages : 564 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Targeted Radionuclide Therapy by : Tod W. Speer

Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.

Sampson's Textbook of Radiopharmacy

Author : Tony Theobald
Publisher :
ISBN 13 : 9780853697893
Total Pages : 725 pages
Book Rating : 4.6/5 (978 download)

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Book Synopsis Sampson's Textbook of Radiopharmacy by : Tony Theobald

Download or read book Sampson's Textbook of Radiopharmacy written by Tony Theobald and published by . This book was released on 2011 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook brings together information on advances in radiopharmacy, providing a basic guide to the art and science of the field. This edition has been completely revised and updated to reflect developments in the science and practice of radiopharmacy that have taken place over the last ten years. It is divided into 6 sections: physics applied to radiopharmacy, medicinal radio-elements, radiopharmacology and radiopharmacokinetics, radiopharmaceutics, formulation, preparation and quality assurance, radiopharmacy practice, new techniques for design and testing of radiopharmaceuticals.

Molybdenum-99 for Medical Imaging

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309445310
Total Pages : 264 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Molybdenum-99 for Medical Imaging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Molybdenum-99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Nuclear Medicine Physics

Author : Dale L. Bailey
Publisher :
ISBN 13 : 9789201438102
Total Pages : 0 pages
Book Rating : 4.4/5 (381 download)

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Book Synopsis Nuclear Medicine Physics by : Dale L. Bailey

Download or read book Nuclear Medicine Physics written by Dale L. Bailey and published by . This book was released on 2015-03-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides the basis for the education of medical physicists initiating their university studies in the field of nuclear medicine. The handbook includes 20 chapters and covers topics relevant to nuclear medicine physics, including basic physics for nuclear medicine, radionuclide production, imaging and non-imaging detectors, quantitative nuclear medicine, internal dosimetry in clinical practice and radionuclide therapy. It provides, in the form of a syllabus, a comprehensive overview of the basic medical physics knowledge required for the practice of medical physics in modern nuclear medicine.

Nuclear Medicine: The Requisites

Author : Harvey A. Ziessman, MD
Publisher : Elsevier Health Sciences
ISBN 13 : 0323082998
Total Pages : 466 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Nuclear Medicine: The Requisites by : Harvey A. Ziessman, MD

Download or read book Nuclear Medicine: The Requisites written by Harvey A. Ziessman, MD and published by Elsevier Health Sciences. This book was released on 2013-03-21 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the essential tools you need to make an accurate diagnosis with Nuclear Medicine: The Requisites! The newest edition of his bestselling volume by Drs. Harvey Ziessman, Janis O'Malley, and James Thrall delivers the conceptual, factual, and interpretive information you need for effective clinical practice in nuclear medicine imaging, as well as for certification and recertification review. Prepare for the written board exam and for clinical practice with critical information on nuclear medicine physics, detection and instrumentation, SPECT and PET imaging, and clinical nuclear medicine imaging. Get the best results from today's most technologically advanced approaches, including hybrid imaging, PET/CT, and SPECT/CT, as well as recent developments in instrumentation, radiopharmaceuticals, and molecular imaging. Clearly visualize the findings you're likely to see in practice and on exams with nearly 200 vibrant new full-color images. Access the fully searchable text and downloadable images online at www.expertconsult.com.

Basics of Radiopharmacy

Author : Buck A. Rhodes
Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Basics of Radiopharmacy by : Buck A. Rhodes

Download or read book Basics of Radiopharmacy written by Buck A. Rhodes and published by . This book was released on 1978 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Radiation in Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309175674
Total Pages : 321 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiation in Medicine by : Institute of Medicine

Download or read book Radiation in Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 1996-03-25 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Does radiation medicine need more regulation or simply better-coordinated regulation? This book addresses this and other questions of critical importance to public health and safety. The issues involved are high on the nation's agenda: the impact of radiation on public safety, the balance between federal and state authority, and the cost-benefit ratio of regulation. Although incidents of misadministration are rare, a case in Pennsylvania resulting in the death of a patient and the inadvertent exposure of others to a high dose of radiation drew attention to issues concerning the regulation of ionizing radiation in medicine and the need to examine current regulatory practices. Written at the request from the Nuclear Regulatory Commission (NRC), Radiation in Medicine reviews the regulation of ionizing radiation in medicine, focusing on the NRC's Medical Use Program, which governs the use of reactor-generated byproduct materials. The committee recommends immediate action on enforcement and provides longer term proposals for reform of the regulatory system. The volume covers: Sources of radiation and their use in medicine. Levels of risk to patients, workers, and the public. Current roles of the Nuclear Regulatory Commission, other federal agencies, and states. Criticisms from the regulated community. The committee explores alternative regulatory structures for radiation medicine and explains the rationale for the option it recommends in this volume. Based on extensive research, input from the regulated community, and the collaborative efforts of experts from a range of disciplines, Radiation in Medicine will be an important resource for federal and state policymakers and regulators, health professionals involved in radiation treatment, developers and producers of radiation equipment, insurance providers, and concerned laypersons.

Nuclear Medicine and PET/CT - E-Book

Author : Paul E. Christian
Publisher : Elsevier Health Sciences
ISBN 13 : 0323277047
Total Pages : 767 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Nuclear Medicine and PET/CT - E-Book by : Paul E. Christian

Download or read book Nuclear Medicine and PET/CT - E-Book written by Paul E. Christian and published by Elsevier Health Sciences. This book was released on 2013-08-09 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to procedures and technologies, Nuclear Medicine and PET/CT: Technology and Techniques provides a single source for state-of-the-art information on all aspects of nuclear medicine. Coverage includes relevant anatomy and physiology and discusses each procedure in relation to the specific use of radiopharmaceuticals and the instruments required. Edited by experts in nuclear imaging and PET/CT, Paul E. Christian and Kristen M. Waterstram-Rich, this edition has a new chapter on MRI as it relates to nuclear medicine and includes practical, step-by-step instructions for procedures. PET/CT focus with hybrid PET/CT studies in several chapters provides cutting-edge information that is especially beneficial to working technologists. CT Physics and Instrumentation chapter introduces CT as it is applied to PET imaging for combined PET/CT studies. Authoritative, comprehensive resource conveys state-of-the-art information, eliminating the need to search for information in other sources. Foundation chapters cover basic math, statistics, physics, instrumentation, computers, lab science, radiochemistry, and pharmacology, allowing you to understand how and why procedures are performed. Accessible writing style and approach to basic science subjects simplifies topics, progressing from fundamentals to more complex concepts. More than 50 practice problems in the math and statistics chapter let you brush up on basic math skills, with answers provided in the back of the book. Key terms, chapter outlines, learning objectives, and suggested readings help you organize your study. A table of radionuclides used in nuclear medicine and PET is provided in the appendix for quick reference. A glossary provides definitions of key terms and important concepts. High-profile editors and contributors come from a variety of educational and clinical settings, providing a broad philosophic and geographic perspective. New MRI Physics, Instrumentation and Clinical Introduction chapter provides important background on MRI and its relationship with nuclear medicine. Procedures boxes in body systems chapters provide step-by-step descriptions of clinical procedures. Updates and revisions keep you current with the latest advances. Expanded 16-page color insert includes more diagnostic images demonstrating realistic scans found in practice.