Molybdenum-99 for Medical Imaging

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Author :
Publisher : National Academies Press
ISBN 13 : 0309445310
Total Pages : 264 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Molybdenum-99 for Medical Imaging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Molybdenum-99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Molybdenum-99 for Medical Imaging

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Author :
Publisher : National Academies Press
ISBN 13 : 0309445345
Total Pages : 264 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Molybdenum-99 for Medical Imaging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Molybdenum-99 for Medical Imaging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-28 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.

Medical Isotope Production Without Highly Enriched Uranium

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Publisher : National Academies Press
ISBN 13 : 0309130395
Total Pages : 220 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Medical Isotope Production Without Highly Enriched Uranium by : National Research Council

Download or read book Medical Isotope Production Without Highly Enriched Uranium written by National Research Council and published by National Academies Press. This book was released on 2009-06-27 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.

Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets

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Author :
Publisher : National Academies Press
ISBN 13 : 030946627X
Total Pages : 87 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets by : National Academies of Sciences, Engineering, and Medicine

Download or read book Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-12 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.

The Supply of Medical Isotopes

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Publisher :
ISBN 13 : 9789264625099
Total Pages : 122 pages
Book Rating : 4.6/5 (25 download)

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Book Synopsis The Supply of Medical Isotopes by :

Download or read book The Supply of Medical Isotopes written by and published by . This book was released on 2019 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report explores the main reasons behind the unreliable supply of Technetium-99m (Tc-99m) in health-care systems and policy options to address the issue. Tc-99m is used in 85% of nuclear medicine diagnostic scans performed worldwide – around 30 million patient examinations every year. These scans allow diagnoses of diseases in many parts of the human body, including the skeleton, heart and circulatory system, and the brain. Medical isotopes are subject to radioactive decay and have to be delivered just-in-time through a complex supply chain. However, ageing production facilities and a lack of investment have made the supply of Tc-99m unreliable. This report analyses the use and substitutability of Tc-99m in health care, health-care provider payment mechanisms for scans, and the structure of the supply chain. It concludes that the main reasons for unreliable supply are that production is not economically viable and that the structure of the supply chain prevents producers from charging prices that reflect the full costs of production and supply.

Advancing Nuclear Medicine Through Innovation

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Publisher : National Academies Press
ISBN 13 : 0309134153
Total Pages : 173 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council

Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors

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Publisher : National Academies Press
ISBN 13 : 0309379210
Total Pages : 205 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors by : National Academies of Sciences, Engineering, and Medicine

Download or read book Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-02-12 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued presence of highly enriched uranium (HEU) in civilian installations such as research reactors poses a threat to national and international security. Minimization, and ultimately elimination, of HEU in civilian research reactors worldwide has been a goal of U.S. policy and programs since 1978. Today, 74 civilian research reactors around the world, including 8 in the United States, use or are planning to use HEU fuel. Since the last National Academies of Sciences, Engineering, and Medicine report on this topic in 2009, 28 reactors have been either shut down or converted from HEU to low enriched uranium fuel. Despite this progress, the large number of remaining HEU-fueled reactors demonstrates that an HEU minimization program continues to be needed on a worldwide scale. Reducing the Use of Highly Enriched Uranium in Civilian Research Reactors assesses the status of and progress toward eliminating the worldwide use of HEU fuel in civilian research and test reactors.

Technetium-99m Pharmaceuticals

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Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle

Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

An Introduction to the Physics of Nuclear Medicine

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Author :
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643270346
Total Pages : 95 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis An Introduction to the Physics of Nuclear Medicine by : Laura Harkness-Brennan

Download or read book An Introduction to the Physics of Nuclear Medicine written by Laura Harkness-Brennan and published by Morgan & Claypool Publishers. This book was released on 2018-06-27 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complexity and vulnerability of the human body has driven the development of a diverse range of diagnostic and therapeutic techniques in modern medicine. The Nuclear Medicine procedures of Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) and Radionuclide Therapy are well-established in clinical practice and are founded upon the principles of radiation physics. This book will offer an insight into the physics of nuclear medicine by explaining the principles of radioactivity, how radionuclides are produced and administered as radiopharmaceuticals to the body and how radiation can be detected and used to produce images for diagnosis. The treatment of diseases such as thyroid cancer, hyperthyroidism and lymphoma by radionuclide therapy will also be explored.

Isotopes for Medicine and the Life Sciences

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Publisher : National Academies Press
ISBN 13 : 0309176697
Total Pages : 144 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Isotopes for Medicine and the Life Sciences by : Institute of Medicine

Download or read book Isotopes for Medicine and the Life Sciences written by Institute of Medicine and published by National Academies Press. This book was released on 1995-01-27 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive isotopes and enriched stable isotopes are used widely in medicine, agriculture, industry, and science, where their application allows us to perform many tasks more accurately, more simply, less expensively, and more quickly than would otherwise be possible. Indeed, in many casesâ€"for example, biological tracersâ€"there is no alternative. In a stellar example of "technology transfer" that began before the term was popular, the Department of Energy (DOE) and its predecessors has supported the development and application of isotopes and their transfer to the private sector. The DOE is now at an important crossroads: Isotope production has suffered as support for DOE's laboratories has declined. In response to a DOE request, this book is an intensive examination of isotope production and availability, including the education and training of those who will be needed to sustain the flow of radioactive and stable materials from their sources to the laboratories and medical care facilities in which they are used. Chapters include an examination of enriched stable isotopes; reactor and accelerator-produced radionuclides; partnerships among industries, national laboratories, and universities; and national isotope policy.

Radiologic Guide to Orthopedic Devices

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Publisher : Cambridge University Press
ISBN 13 : 1107085624
Total Pages : 357 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Radiologic Guide to Orthopedic Devices by : Tim B. Hunter

Download or read book Radiologic Guide to Orthopedic Devices written by Tim B. Hunter and published by Cambridge University Press. This book was released on 2017-05-11 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference on radiologic appearance, uses and complications of orthopedic devices, for radiologists, orthopedists, physicians, and students.

RadTool Nuclear Medicine Flash Facts

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Publisher : Springer
ISBN 13 : 3319246364
Total Pages : 237 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis RadTool Nuclear Medicine Flash Facts by : Bital Savir-Baruch

Download or read book RadTool Nuclear Medicine Flash Facts written by Bital Savir-Baruch and published by Springer. This book was released on 2016-07-28 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a learning aid and reference tool that provides all the important information pertaining to radioactive tracers within a single, easy-to-read volume. It introduces a new learning methodology that will help the reader to recall key facts on each tracer, including production, physical and chemical characteristics, study protocols, mechanism of action, distribution, and clearance. In addition, normal and abnormal tracer distributions are graphically reproduced on an outline of the human body using multiple colors. The book will be of value for all radiologists and medical students seeking a reliable source of essential information on radioactive tracers that can be readily consulted during everyday practice and used in preparation for examinations.

FRCR Physics Notes

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Publisher :
ISBN 13 : 9781999988524
Total Pages : 320 pages
Book Rating : 4.9/5 (885 download)

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Book Synopsis FRCR Physics Notes by : Christopher Clarke

Download or read book FRCR Physics Notes written by Christopher Clarke and published by . This book was released on 2020-11-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive medical imaging physics notes aimed at those sitting the first FRCR physics exam in the UK and covering the scope of the Royal College of Radiologists syllabus. Written by Radiologists, the notes are concise and clearly organised with 100's of beautiful diagrams to aid understanding. The notes cover all of radiology physics, including basic science, x-ray imaging, CT, ultrasound, MRI, molecular imaging, and radiation dosimetry, protection and legislation. Although aimed at UK radiology trainees, it is also suitable for international residents taking similar examinations, postgraduate medical physics students and radiographers. The notes provide an excellent overview for anyone interested in the physics of radiology or just refreshing their knowledge. This third edition includes updates to reflect new legislation and many new illustrations, added sections, and removal of content no longer relevent to the FRCR physics exam. This edition has gone through strict critique and evaluation by physicists and other specialists to provide an accurate, understandable and up-to-date resource. The book summarises and pulls together content from the FRCR Physics Notes at Radiology Cafe and delivers it as a paperback or eBook for you to keep and read anytime. There are 7 main chapters, which are further subdivided into 60 sub-chapters so topics are easy to find. There is a comprehensive appendix and index at the back of the book.

Essentials of Nuclear Medicine and Molecular Imaging E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323567894
Total Pages : 624 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Essentials of Nuclear Medicine and Molecular Imaging E-Book by : Fred A. Mettler

Download or read book Essentials of Nuclear Medicine and Molecular Imaging E-Book written by Fred A. Mettler and published by Elsevier Health Sciences. This book was released on 2018-08-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.

Radiopharmaceutical Chemistry

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Publisher : Springer
ISBN 13 : 3319989472
Total Pages : 648 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Radiopharmaceutical Chemistry by : Jason S. Lewis

Download or read book Radiopharmaceutical Chemistry written by Jason S. Lewis and published by Springer. This book was released on 2019-04-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Neuroendocrine Tumors: A Multidisciplinary Approach

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Author :
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318027731
Total Pages : 270 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Neuroendocrine Tumors: A Multidisciplinary Approach by : M. Papotti

Download or read book Neuroendocrine Tumors: A Multidisciplinary Approach written by M. Papotti and published by Karger Medical and Scientific Publishers. This book was released on 2015-08-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term ‘carcinoid’ entered medical literature over 100 years ago to describe a peculiar intestinal epithelial neoplasm. Since then, a large body of literature has expanded the concept of carcinoid, later replaced by the term ‘NeuroEndocrine Tumor’ (NET), defining a wide spectrum of peculiar tumors, potentially affecting all organs and tissues, originating from neuroendocrine cells, sharing, but, at the same time, keeping, pathognomonic pathological, radiological and clinical features. This book provides an authoritative overview of the epidemiological, clinical, genetic, molecular and pathological characteristics of NETs and highlights the most relevant controversial issues in the classification, diagnosis and therapy. Furthermore the new frontiers in the field of medical therapies are presented, through a multidisciplinary and translational approach. Considering the fact that NETs have been recently demonstrated less rare as considered so far, 'Neuroendocrine Tumors: A Multidisciplinary Approach' is a must read for endocrinologists, gastroenterologists, endocrine surgeons, as well as pathologists, nuclear medicine physicians and radiologists focused on NET.

MRI Made Easy

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Publisher :
ISBN 13 : 9783000384417
Total Pages : 101 pages
Book Rating : 4.3/5 (844 download)

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Book Synopsis MRI Made Easy by : Hans H. Schild

Download or read book MRI Made Easy written by Hans H. Schild and published by . This book was released on 2012 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: