Ntp Technical Report on the Toxicology and Carcinogenesis Studies of Nitrofurantoin (Cas No. 67-20-9) in F344/N Rats and B6c3f Mice (Feed Studies)

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Publisher : Palala Press
ISBN 13 : 9781341774713
Total Pages : 228 pages
Book Rating : 4.7/5 (747 download)

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Book Synopsis Ntp Technical Report on the Toxicology and Carcinogenesis Studies of Nitrofurantoin (Cas No. 67-20-9) in F344/N Rats and B6c3f Mice (Feed Studies) by : National Toxicology Program (U S )

Download or read book Ntp Technical Report on the Toxicology and Carcinogenesis Studies of Nitrofurantoin (Cas No. 67-20-9) in F344/N Rats and B6c3f Mice (Feed Studies) written by National Toxicology Program (U S ) and published by Palala Press. This book was released on 2015-09-06 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

NTP Technical Report on the Toxicology and Carcinogenesis Studies of Isobutyl Nitrite (CAS No. 542-56-3) in F344/N Rats and B6C3F1 Mice (inhalation Studies).

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ISBN 13 :
Total Pages : 308 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Isobutyl Nitrite (CAS No. 542-56-3) in F344/N Rats and B6C3F1 Mice (inhalation Studies). by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Isobutyl Nitrite (CAS No. 542-56-3) in F344/N Rats and B6C3F1 Mice (inhalation Studies). written by and published by . This book was released on 1996 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (feed Studies)

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ISBN 13 :
Total Pages : 290 pages
Book Rating : 4.:/5 (772 download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (feed Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Primidone (CAS No. 125-33-7) in F344/N Rats and B6C3F1 Mice (feed Studies) written by and published by . This book was released on 2000 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,2-bis(bromomethyl)-1,3-propanediol (FR-1138) (CAS No. 3296-90-0) in F344/N Rats and B6C3F1 Mice (feed Studies)

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ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,2-bis(bromomethyl)-1,3-propanediol (FR-1138) (CAS No. 3296-90-0) in F344/N Rats and B6C3F1 Mice (feed Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 2,2-bis(bromomethyl)-1,3-propanediol (FR-1138) (CAS No. 3296-90-0) in F344/N Rats and B6C3F1 Mice (feed Studies) written by and published by . This book was released on 1996 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Bulletin

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Publisher :
ISBN 13 :
Total Pages : 28 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis NTP Technical Bulletin by : National Toxicology Program (U.S.)

Download or read book NTP Technical Bulletin written by National Toxicology Program (U.S.) and published by . This book was released on 1980 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on the Toxicology and Carcinogenesis Studies of 3,3'-dimethylbenzidine Dihydrochloride (CAS No. 612-82-8) in F344/N Rats (drinking Water Studies)

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Publisher :
ISBN 13 :
Total Pages : 246 pages
Book Rating : 4.:/5 (327 download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of 3,3'-dimethylbenzidine Dihydrochloride (CAS No. 612-82-8) in F344/N Rats (drinking Water Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of 3,3'-dimethylbenzidine Dihydrochloride (CAS No. 612-82-8) in F344/N Rats (drinking Water Studies) written by and published by . This book was released on 1991 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Bulletin

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ISBN 13 :
Total Pages : 128 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis NTP Technical Bulletin by :

Download or read book NTP Technical Bulletin written by and published by . This book was released on 1979 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicology and Carcinogenesis Studies of Anthraquinone in F344/N Rats and B6C3F, Mice

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Publisher :
ISBN 13 : 9781422303498
Total Pages : 358 pages
Book Rating : 4.3/5 (34 download)

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Book Synopsis Toxicology and Carcinogenesis Studies of Anthraquinone in F344/N Rats and B6C3F, Mice by : R. D. Irwin

Download or read book Toxicology and Carcinogenesis Studies of Anthraquinone in F344/N Rats and B6C3F, Mice written by R. D. Irwin and published by . This book was released on 2006-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anthraquinone is used as an intermediate in the manufacture of dyes & pigments, an additive in the kraft pulping process in the paper industry, a catalyst in the isomerization of vegetable oils, an accelerator in nickel electroplating, & as a bird repellent. The Nat. Toxicology Program (NTP) studied anthraquinone to determine if it caused cancer in rats or mice. They conclude that anthraquinone caused cancer of the kidney & urinary bladder in male & female rats & of the liver in female rates. The occurrence of some liver tumors in male rats may have been related to anthraquinone exposure. The NTP concludes that anthraquinone caused liver cancer in male & female mice, & thyroid gland tumors in mice may have been related to anthraquinone. Illus.

Technical Report on Toxicology and Carcinogenesis Studies of A-Methylstyrene (CAS No. 98-83-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

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Publisher : DIANE Publishing
ISBN 13 : 1428988866
Total Pages : 464 pages
Book Rating : 4.4/5 (289 download)

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Book Synopsis Technical Report on Toxicology and Carcinogenesis Studies of A-Methylstyrene (CAS No. 98-83-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) by : M. E. Wyde

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of A-Methylstyrene (CAS No. 98-83-9) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) written by M. E. Wyde and published by DIANE Publishing. This book was released on 2008-04 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: a-Methylstyrene is used to make heat-resistant acrylonitrile-butadiene-styrene resins & polymers. This report studies the effects of a-methylstyrene on male & female rats & mice to identify potential toxic or cancer-related hazards. It concludes that exposure to a-methylstyrene in the air caused kidney tumors, & possibly mononuclear cell leukemia, in male rats. It concludes that a-methylstyrene caused liver cancer in female mice, & also possibly in male mice. Charts, tables, graphs & plates.

NTP Technical Report on the Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate (CAS No. 10101-97-0) in F344/N Rats and B6C3F1 Mice (inhalation Studies).

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Publisher :
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate (CAS No. 10101-97-0) in F344/N Rats and B6C3F1 Mice (inhalation Studies). by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate (CAS No. 10101-97-0) in F344/N Rats and B6C3F1 Mice (inhalation Studies). written by and published by . This book was released on 1996 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Toxicity Study Reports

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Publisher :
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.:/5 (4 download)

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Book Synopsis NTP Toxicity Study Reports by :

Download or read book NTP Toxicity Study Reports written by and published by . This book was released on 1991 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on Toxicity Studies of Black Newsprint Inks Administered Topically to F344/N Rats and C3H Mice

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ISBN 13 :
Total Pages : 70 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis NTP Technical Report on Toxicity Studies of Black Newsprint Inks Administered Topically to F344/N Rats and C3H Mice by : Joel F. Mahler

Download or read book NTP Technical Report on Toxicity Studies of Black Newsprint Inks Administered Topically to F344/N Rats and C3H Mice written by Joel F. Mahler and published by . This book was released on 1992 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicology and Carcinogenesis Studies of Benzophenone in F344/N Rats and B6C3F1 Mice

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ISBN 13 : 9781422307205
Total Pages : 264 pages
Book Rating : 4.3/5 (72 download)

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Book Synopsis Toxicology and Carcinogenesis Studies of Benzophenone in F344/N Rats and B6C3F1 Mice by : M. C. Rhodes

Download or read book Toxicology and Carcinogenesis Studies of Benzophenone in F344/N Rats and B6C3F1 Mice written by M. C. Rhodes and published by . This book was released on 2006-10-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol (CAS No. 107-19-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

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ISBN 13 : 9781437910681
Total Pages : 172 pages
Book Rating : 4.9/5 (16 download)

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Book Synopsis Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol (CAS No. 107-19-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) by : J. J. Butler

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of Propargyl Alcohol (CAS No. 107-19-7) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) written by J. J. Butler and published by . This book was released on 2009-03 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Propargyl alcohol is a commercially available acetylenic primary alcohol. It is used in a variety of chemical manufacturing processes and to protect steel from becoming brittle. The researchers studied propargyl alcohol to determine if it caused cancer in rats or mice. All groups of animals exposed to propargyl alcohol experienced a variety of lesions in the epithelial tissues of the nose, including hyperplase, metaplasia, and inflammation. Adenomas of the respiratory epithelium of the nose were observed in male rats and in male and female mice exposed to propargyl alcohol. The rate of mononuclear cell leukemia was also increased in exposed male rats, and the rate of Harderian gland edenomas was increased in exposed male mice. Illus.

Toxicology and Carcinogenesis Studies of Decalin

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ISBN 13 : 9780756749453
Total Pages : 315 pages
Book Rating : 4.7/5 (494 download)

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Book Synopsis Toxicology and Carcinogenesis Studies of Decalin by : P. C. Chan

Download or read book Toxicology and Carcinogenesis Studies of Decalin written by P. C. Chan and published by . This book was released on 2005-08 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decalin is used as an industrial solvent for naphthalene, fats, resins, oils, & waxes. It is also used in lacquers, paints, & varnishes; shoe polishes & floor waxes; & motor fuels & lubricants. Other applications include use as a paint thinner & remover, a patent fuel in stoves, a high-density fuel in submarine-launched cruise missile systems, & in stain removal & cleaning machinery. Decalin was nominated for study by the Nat. Cancer Institute because of its chemical structure, its potential for consumer exposure, & a lack of adequate testing of the chemical. Illustrations.

NTP Technical Report on the Toxicology and Carcinogenesis Studies of P-chloro-α,α,α-trifluorotoluene (CASRN 98-56-6) in Sprague Dawley (HSD: Sprague Dawley® SD®) Rats and B6C3F1/N Mice (inhalation Studies)

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (145 download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of P-chloro-α,α,α-trifluorotoluene (CASRN 98-56-6) in Sprague Dawley (HSD: Sprague Dawley® SD®) Rats and B6C3F1/N Mice (inhalation Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of P-chloro-α,α,α-trifluorotoluene (CASRN 98-56-6) in Sprague Dawley (HSD: Sprague Dawley® SD®) Rats and B6C3F1/N Mice (inhalation Studies) written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

NTP Technical Report on the Toxicology and Carcinogenesis Studies of Sodium Tungstate Dihydrate (CASRN 10213-10-2) in Sprague Dawley (Hsd:Sprague Dawley(r) SD(r)) Rats and B6C3F1/N Mice (Drinking Water Studies)

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)

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Book Synopsis NTP Technical Report on the Toxicology and Carcinogenesis Studies of Sodium Tungstate Dihydrate (CASRN 10213-10-2) in Sprague Dawley (Hsd:Sprague Dawley(r) SD(r)) Rats and B6C3F1/N Mice (Drinking Water Studies) by :

Download or read book NTP Technical Report on the Toxicology and Carcinogenesis Studies of Sodium Tungstate Dihydrate (CASRN 10213-10-2) in Sprague Dawley (Hsd:Sprague Dawley(r) SD(r)) Rats and B6C3F1/N Mice (Drinking Water Studies) written by and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: PERINATAL AND THREE-MONTH STUDY IN RATS: Beginning on GD\s6, groups of eight F0\stime-mated female rats were exposed to ST in drinking water throughout gestation and lactation at one of five exposure concentrations (125, 250, 500, 1,000, or 2,000\smg/L) or were provided the vehicle control (deionized water). Groups of 10 F1\srats per sex continued on in the study after weaning and were given drinking water containing the same respective ST concentrations for 3\smonths. There were no significant effects of ST exposure on pregnancy status, maternal survival, or littering parameters. By the end of lactation, dams in the 1,000 and 2,000\smg/L groups showed significant decreases in group mean body weight of approximately 10% and 18%, respectively, and water consumption was significantly decreased for the 500, 1,000, and 2,000\smg/L groups relative to the vehicle control group over the LD\s17 to LD\s21 interval. When adjusted for litter size, the mean body weight of male and female pups in the 2,000\smg/L group on PND\s21 was significantly decreased by approximately 16% and 11%, respectively, compared to the corresponding vehicle control groups. There were no early deaths during the 3-month study. When compared to the vehicle control group, final mean body weights were lower for the 1,000 and 2,000\smg/L males and 2,000 mg/L females. Water consumption was lower for the 1,000 and 2,000\smg/L males and females. The urine xanthine/creatinine ratios were significantly increased in all male and female exposed groups. Serum insulin concentrations were significantly decreased in the 2,000\smg/L males relative to the vehicle control males. Significantly decreased absolute weights were observed in several organs but were considered secondary to body weights reductions. Exposure-related histological lesions were limited to the kidneys and included increased incidences of renal tubule regeneration in the 1,000 and 2,000\smg/L males and females; the increases in the 2,000\smg/L groups were significant relative to the vehicle control group. CONCLUSIONS: Under the conditions of these 2-year drinking water studies, there was no evidence of carcinogenic activity of sodium tungstate dihydrate (ST) in male Hsd:Sprague Dawley(r) SD(r) rats at exposure concentrations of 250, 500, or 1,000\smg/L. There was equivocal evidence of carcinogenic activity of ST in female Hsd:Sprague Dawley(r) SD(r) rats based on increased incidences of C-cell adenoma or carcinoma (combined) of the thyroid gland. There was equivocal evidence of carcinogenic activity of ST in male B6C3F1/N mice based on the occurrences of renal tubule adenoma or carcinoma (combined) in exposed animals. There was no evidence of carcinogenic activity of ST in female B6C3F1/N mice at exposure concentrations of 500, 1,000, or 2,000\smg/L. Exposure to ST in drinking water caused increased incidences of nonneoplastic lesions in the kidney of male and female rats and mice, in the uterus of female rats, in the large intestine of male and female mice, and in the testes of male mice.SYNONYMS: Tungstic acid sodium salt dehydrate.