Novel Therapeutic Target and Drug Development in Neurovascular Retinal Diseases

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Publisher : Frontiers Media SA
ISBN 13 : 2889668681
Total Pages : 153 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Novel Therapeutic Target and Drug Development in Neurovascular Retinal Diseases by : Amy Cheuk Yin Lo

Download or read book Novel Therapeutic Target and Drug Development in Neurovascular Retinal Diseases written by Amy Cheuk Yin Lo and published by Frontiers Media SA. This book was released on 2021-06-08 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases

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Author :
Publisher : Springer Nature
ISBN 13 : 3030566196
Total Pages : 278 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases by : Christopher L. Cioffi

Download or read book Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases written by Christopher L. Cioffi and published by Springer Nature. This book was released on 2020-09-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current state of ocular drug therapy and future therapeutic opportunities for a wide variety of conditions, including Age-related Macular Degeneration, Diabetic Retinopathy and Macular Edema, Glaucoma, and Inherited Retinal Diseases. Retinal diseases are major contributors to moderate or severe vision impairment in adults aged 50 years and older. The respective patient populations for many of these indications is expected to significantly increase as the world population continues to grow older. An improved understanding of the etiological underpinnings of ocular degenerative diseases over the past decade has significantly bolstered ophthalmic drug discovery. In this volume, contributions from leading experts explore the unique challenges faced for ocular drug discovery and delivery providing the reader with detailed information on ocular pharmacokinetics, in vitro, ex vivo and in vivo models for retinal disease pathology and emerging gene therapy treatments. The book is intended for all researchers and clinicians who wish to increase their knowledge on the latest findings in ocular drug therapy.

The Human Eye

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Author :
Publisher : Sinauer
ISBN 13 : 9780878936441
Total Pages : 0 pages
Book Rating : 4.9/5 (364 download)

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Book Synopsis The Human Eye by : Clyde W. Oyster

Download or read book The Human Eye written by Clyde W. Oyster and published by Sinauer. This book was released on 2006-02-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Readable, clear text and hundreds of original anatomical drawings are accompanied by a series of text boxes discussing anatomical methods and ocular surgery, as well as historical 'vignettes', which illustrate how we have come to understand the eye as we do.

Molecular mechanisms in ocular development and disease

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Publisher : Frontiers Media SA
ISBN 13 : 2832528759
Total Pages : 221 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Molecular mechanisms in ocular development and disease by : Rajalekshmy Shyam

Download or read book Molecular mechanisms in ocular development and disease written by Rajalekshmy Shyam and published by Frontiers Media SA. This book was released on 2023-07-04 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ocular Vascular Occlusive Disorders

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Publisher : Springer
ISBN 13 : 3319127810
Total Pages : 863 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Ocular Vascular Occlusive Disorders by : Sohan Singh Hayreh

Download or read book Ocular Vascular Occlusive Disorders written by Sohan Singh Hayreh and published by Springer. This book was released on 2015-02-18 with total page 863 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive account of the pathogenesis, clinical features, and management of ocular vascular occlusive disorders, with the focus very much on the scientific evidence. This offers a sound basis for addressing the many controversies that surround these disorders, which collectively constitute the most common cause of visual impairment or blindness. The book is divided into two sections, the first of which addresses the basic science and encompasses vascular anatomy, blood supply and flow, and retinal tolerance time to acute ischemia. The second, clinical, section covers the presentation, clinical features, diagnosis, and treatment of the full range of vascular occlusive disorders of the retina, the choroid, the anterior segment of the eye, ophthalmic manifestations of carotid artery disease and the optic nerve. Ocular Vascular Occlusive Disorders, written by a distinguished world leader in the field, will be invaluable for general ophthalmologists, and particularly for retina specialists, neuro-ophthalmologists, and researchers.

Textbook of Vascular Medicine

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Publisher : Springer
ISBN 13 : 3030164810
Total Pages : 503 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Textbook of Vascular Medicine by : Rhian M. Touyz

Download or read book Textbook of Vascular Medicine written by Rhian M. Touyz and published by Springer. This book was released on 2019-08-02 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

Webvision

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (53 download)

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Book Synopsis Webvision by : Helga Kolb

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Retinal Pharmacotherapeutics

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318055654
Total Pages : 426 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Retinal Pharmacotherapeutics by : Q.D. Nguyen

Download or read book Retinal Pharmacotherapeutics written by Q.D. Nguyen and published by Karger Medical and Scientific Publishers. This book was released on 2015-10-27 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of pharmacotherapeutics in the management of retinal diseases is rapidly evolving, and a favorable therapy for the patient. Today anti-VEGF agents are used for a range of indications from inflammation-related choroidal neovascularization to macular edema secondary to retinal vein occlusion or diabetic retinopathy. Beyond VEGF, there is an array of target areas under investigation – not only for vascular pathologies such as age-related macular degeneration and diabetic eye disease, but also for degenerative, infectious and inflammatory retinal conditions. This publication discusses many aspects from basic research on the retina, to animal models for retinal drug delivery, retinal diseases that are amenable to pharmacotherapy and also drugs and mechanisms in retinal diseases. Anyone concerned with the management of retinal diseases - the general ophthalmologist and the retina specialist alike – will find this book indispensable reading.

Protein Aggregation and Propagation in Neurodegenerative Diseases

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Publisher : Frontiers Media SA
ISBN 13 : 2832504760
Total Pages : 151 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Protein Aggregation and Propagation in Neurodegenerative Diseases by : Hui Yang

Download or read book Protein Aggregation and Propagation in Neurodegenerative Diseases written by Hui Yang and published by Frontiers Media SA. This book was released on 2022-11-10 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Science of Glaucoma Management

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Publisher : Elsevier
ISBN 13 : 0323884431
Total Pages : 484 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis The Science of Glaucoma Management by : Kevin Gillmann

Download or read book The Science of Glaucoma Management written by Kevin Gillmann and published by Elsevier. This book was released on 2023-05-18 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Science of Glaucoma Management: From Translational Research to Next-Generation Clinical Practice bridges the gap between laboratory research and clinicians by bringing the latest promising research directly from researchers to clinicians long before they translate into clinical advances, and often before they are presented at conferences. Organized as a series of clinically relevant topics written by world-leading experts, this book summarizes the current state of laboratory and translational research and draws on the potential implications for day-to-day clinical practice. It offers new insights and mind-opening statements through contributions from some of the most respected glaucoma research groups. The book allows glaucoma specialists to explore novel ways to refine and rethink their practice based on the latest discoveries in basic sciences and breakthrough technologies, and to gain a better understanding on how their specialty is evolving and how research may shape tomorrow’s practice. Presents a detailed report on the latest translational research and breakthroughs that may transform glaucoma practice Overviews the specialty from a scientific and clinical point-of-view Written by world-renowned clinicians and researchers in the field of glaucoma Includes insights, opinions and recommendations from some of the most prominent scientists and ophthalmologists Covers hot topics and the latest technologies in glaucoma, such as minimally invasive glaucoma surgery, telemedicine, gene therapy, neuroprotection and artificial intelligence

Oxidative Stress Revisited - Major Role in Vascular Diseases

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Publisher : Frontiers Media SA
ISBN 13 : 2889630587
Total Pages : 158 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Oxidative Stress Revisited - Major Role in Vascular Diseases by : Cristina M. Sena

Download or read book Oxidative Stress Revisited - Major Role in Vascular Diseases written by Cristina M. Sena and published by Frontiers Media SA. This book was released on 2019-10-21 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is an underlying factor in health and disease. Reactive oxygen species are produced as a result of normal cellular metabolism. The subsequent altered redox state between the formation and the neutralization of pro-oxidants results in their increased levels and therefore leads to cellular damage. Different research disciplines have increased our knowledge of the importance of this cell redox status and the recognition of oxidative stress as a process with implications for many pathophysiological states. Genetic and environmental factors, nutrition and lifestyle may indicate a pro-oxidative and pro-inflammatory state, linked to alterations in cellular structure and function. Oxidative stress emerges as a common, unifying factor in several conditions including diabetes and cardiovascular diseases. This eBook aims to provide novel data regarding the role played by oxidative stress and inflammation in the development of chronic diseases and the different classes of therapeutics from the bench to the clinic, stressing the awareness of these concepts for the treatment of disease. In addition, articles addressing an overview of the role of oxidative stress in vascular diseases reviewing some current concepts indicating that oxidative stress and inflammation are key mechanisms linking vascular diseases and current state-of-the-art approaches to monitor, prevent and inhibit oxidative stress will be highlighted. There is a close relation between oxidative stress, inflammation and cardiovascular diseases. Despite the great amount of investigation carried out in the field, there are still uncertainties about the mechanisms by which free radicals can modify tissues such as perivascular adipose tissue that ultimately will reflect on vascular function. This eBook will focus on articles that can explore and identify these mechanisms. Concurrent with this understanding of oxidative stress milieu, it is necessary to recognize the need for new pharmacological tools effective in restoring oxidative balance. The abundance of new information and the paradigm shift in our understanding of how antioxidants and other redox-active drugs work in a wide variety of vascular diseases will be specifically highlighted. This eBook will provide a comprehensive, up-to-date source of information on the design and mechanistic, pharmacological, and medicinal aspects of redox-active therapeutics. Finally, a unique feature of the eBook is to provide a way to foster an enthralling discussion revisiting old paradigms and finding new solutions for the treatment of vascular diseases. The topic will include original research articles, hypotheses, perspectives and (mini)reviews from experts in the field. The next decade shows promise for the translation of this body of knowledge to novel human therapeutics and this eBook will enable to increment our knowledge in this field.

Cerebrovascular and Neurodegenerative Diseases – New Insights into Molecular Cell Biology and Therapeutic Targets

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Publisher : Frontiers Media SA
ISBN 13 : 2889634426
Total Pages : 317 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Cerebrovascular and Neurodegenerative Diseases – New Insights into Molecular Cell Biology and Therapeutic Targets by : Sikha Saha

Download or read book Cerebrovascular and Neurodegenerative Diseases – New Insights into Molecular Cell Biology and Therapeutic Targets written by Sikha Saha and published by Frontiers Media SA. This book was released on 2020-01-30 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Retinal and Choroidal Angiogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 1402067801
Total Pages : 567 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Retinal and Choroidal Angiogenesis by : John Penn

Download or read book Retinal and Choroidal Angiogenesis written by John Penn and published by Springer Science & Business Media. This book was released on 2008-01-19 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance.

Retina

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Publisher : Elsevier Health Sciences
ISBN 13 : 1455707376
Total Pages : 2498 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Retina by : David R. Hinton

Download or read book Retina written by David R. Hinton and published by Elsevier Health Sciences. This book was released on 2013 with total page 2498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice.

Intraocular Inflammation

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Publisher : Springer
ISBN 13 : 3540753877
Total Pages : 1530 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Intraocular Inflammation by : Manfred Zierhut

Download or read book Intraocular Inflammation written by Manfred Zierhut and published by Springer. This book was released on 2016-01-12 with total page 1530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-structured and lavishly illustrated book is a comprehensive reference on intraocular inflammation that encompasses all anatomic forms, settings and etiologies. Individual sections are devoted to uveitis associated with systemic disorders, uveitis syndromes restricted to the eye, bacterial uveitis, viral uveitis, fungal uveitis, parasitic uveitis, uveitis caused by other microbes, traumatic uveitis, and masquerade syndromes. Chapters on the different forms of uveitis are in a homogeneous reader-friendly format, with identification of core messages, explanation of etiology and pathogenesis, up-to-date information on diagnostics and differential diagnosis and guidance on the most appropriate forms of treatment and prognosis. Helpful flow charts are included to assist in identification of potential underlying disorders and the reader will also have online access to one hundred informative case reports demonstrating the different courses of intraocular inflammation. The authors are world experts keen to share their vast experience with the reader. Intraocular Inflammation will be a valuable resource for all physicians who deal with patients with inflammatory eye disease.

Neurodegenerative Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 1461406536
Total Pages : 421 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Neurodegenerative Diseases by : Shamim I. Ahmad

Download or read book Neurodegenerative Diseases written by Shamim I. Ahmad and published by Springer Science & Business Media. This book was released on 2012-03-12 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Retina E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455737801
Total Pages : 2498 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Retina E-Book by : Charles P. Wilkinson

Download or read book Retina E-Book written by Charles P. Wilkinson and published by Elsevier Health Sciences. This book was released on 2012-11-01 with total page 2498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.