Novel Molecular Targets And Treatments For Gastroesophageal Cancer 2nd Edition

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Novel Molecular Targets and Treatments for Gastroesophageal Cancer, 2nd edition

Author : Bin Li
Publisher : Frontiers Media SA
ISBN 13 : 2832541836
Total Pages : 236 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Novel Molecular Targets and Treatments for Gastroesophageal Cancer, 2nd edition by : Bin Li

Download or read book Novel Molecular Targets and Treatments for Gastroesophageal Cancer, 2nd edition written by Bin Li and published by Frontiers Media SA. This book was released on 2024-01-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastroesophageal cancer is among the most common malignant diseases worldwide and is associated with high mortality rates, leading to a substantial burden on public health and healthcare systems around the world. Chemotherapeutic drugs have achieved great success in the treatment of esophageal cancer; however, they also bring cytotoxicity to other organs and often have serious side effects. With the development of molecular diagnostics and biomarker discovery, the application of precision medicine has emerged to improve clinical outcomes. New antineoplastic therapy development is a timely topic in light of the recent development of precision medicine. New biotherapies aim to inhibit or regulate different targets, which are thought to be functionally selective or overexpressed in some types of tumors. In particular, progress has been made to understand the molecular biology of gastrointestinal cancer, resulting in the discovery of various molecular targets, such as KRAS, PD-1, PD-L1, EGFR, HER2 and VEGF. Moreover, anticancer agents, such as pembrolizumab, olaparib, trastuzumab, bevacizumab, either as single agents or in combination with conventional chemotherapy, have become part of the standard of care for treatment of advanced gastroesophageal cancer. This Research Topic provides a platform for recent studies on novel molecular targets and treatments for gastroesophageal cancer. Both Original Research articles and Reviews are welcome. Subjects may include but are not limited to: 1) Oncogenes and tumor suppressors; 2) Drug sensitivity/resistance; 3) Tumor metastasis and tumor microenvironment; 4) Biomarker discovery and epigenetic regulation.

Molecular Biomarkers for Gastric Cancer, 2nd edition

Author : Kecheng Zhang
Publisher : Frontiers Media SA
ISBN 13 : 2832552366
Total Pages : 394 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Molecular Biomarkers for Gastric Cancer, 2nd edition by : Kecheng Zhang

Download or read book Molecular Biomarkers for Gastric Cancer, 2nd edition written by Kecheng Zhang and published by Frontiers Media SA. This book was released on 2024-07-31 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer (GC) represents a serious health problem on a global scale. Despite some recent advances in the field, the prognosis in GC remains poor. A better understanding of molecular biology, which would lead to improved treatment options, is needed. Many potential biomarkers of prognostic significance have been identified. However, inhibition of only HER2 protein has led to a modest survival benefit. A deeper understanding of the pathogenesis and biological features of gastric cancer, including the identification and characterization of diagnostic, prognostic, predictive, and therapeutic biomarkers, hopefully will provide improved clinical outcomes. This Research Topic aims to provide a comprehensive overview on recent progress in emerging molecular biomarkers for gastric cancer. We welcome the submission of Review and Original Research articles covering, but not limited to, the following topics: 1)Novel diagnostic molecules to improve the early detection rate for gastric cancer 2)Novel prognostic molecules to stratify gastric cancer patients into different risk 3)Novel therapeutic biomarker which could serve as target for treating gastric cancer 4)Novel biomarker to predict chemotherapy response of gastric cancer patients

Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract

Author : Marnix Jansen
Publisher : Springer
ISBN 13 : 3319413880
Total Pages : 487 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract by : Marnix Jansen

Download or read book Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract written by Marnix Jansen and published by Springer. This book was released on 2016-08-29 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett’s esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett’s esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer. Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer’s Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.

Hepatocellular Carcinoma

Author : Yujin Hoshida
Publisher : Springer
ISBN 13 : 3030215407
Total Pages : 366 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Hepatocellular Carcinoma by : Yujin Hoshida

Download or read book Hepatocellular Carcinoma written by Yujin Hoshida and published by Springer. This book was released on 2019-08-05 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Identifying Novel Biomarkers in Bladder Cancer, 2nd edition

Author : Thornsten Ecke
Publisher : Frontiers Media SA
ISBN 13 : 2832530516
Total Pages : 262 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Identifying Novel Biomarkers in Bladder Cancer, 2nd edition by : Thornsten Ecke

Download or read book Identifying Novel Biomarkers in Bladder Cancer, 2nd edition written by Thornsten Ecke and published by Frontiers Media SA. This book was released on 2023-07-18 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bladder cancer is one of the most common urological diseases with a high mortality rate and poor prognosis. It is currently ranked as the 10th most common malignancy worldwide. The majority of bladder cancer patients have been found to be diagnosed with non-muscle invasive bladder cancer (NMIBC) and the remaining, are diagnosed with muscle-invasive bladder cancer (MIBC). Although there have been advances in the treatment and therapies provided for bladder cancer patients, the survival rate remains low, primarily due to recurrence and metastasis of the disease following treatment. Surgical treatment is currently the most common form including radical cystectomy which is the standard form of treatment combined with neoadjuvant chemotherapy. However, the 5-year overall survival rate is 50%. Therefore, further studies are required to understand the molecular mechanisms involved in the progression of bladder cancer and identify novel biomarkers to act as a diagnostic tool for patients. There have been many studies involving the detection of biomarkers in bladder cancer in addition to monitoring disease recurrence to understand the impact and predict potential outcomes. A variety of urine biomarkers have been developed to detect bladder cancer and prognostic risk stratification including mutational DNA and the levels of RNA expression. Circulating tumor cells have also been identified as a potential biomarker for bladder cancer patients. However, there are significant challenges as bladder cancer has demonstrated high levels of cellular and molecular heterogeneity and some markers do not have sufficient sensitivity for accurate detection. Therefore, further studies are required to continue to identify new novel biomarkers for bladder cancer. The aim of this Research Topic is to discuss novel biomarkers in bladder cancer and how it impacts the disease progression and the survival rate for bladder cancer patients.

Novel Targets and Biomarkers in Solid Tumors, 2nd Edition

Author : Dong-Hua Yang
Publisher : Frontiers Media SA
ISBN 13 : 2889638790
Total Pages : 285 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Novel Targets and Biomarkers in Solid Tumors, 2nd Edition by : Dong-Hua Yang

Download or read book Novel Targets and Biomarkers in Solid Tumors, 2nd Edition written by Dong-Hua Yang and published by Frontiers Media SA. This book was released on 2020-07-16 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Barrett's Esophagus and Esophageal Adenocarcinoma

Author : Prateek Sharma
Publisher : John Wiley & Sons
ISBN 13 : 1405171537
Total Pages : 312 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Barrett's Esophagus and Esophageal Adenocarcinoma by : Prateek Sharma

Download or read book Barrett's Esophagus and Esophageal Adenocarcinoma written by Prateek Sharma and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The leading reference text entirely devoted to this increasinglysignificant condition This text is dedicated to Barrett’s esophagus and providesrecent evidence and current approaches to patient management. Ithas been completely revised, updated and extended to include thelatest research findings and describes how these affect day-to-dayclinical practice. It includes seven new chapters and even more color images thanthe last edition. Each chapter, written by the leadinginternational experts in the field, provides clear, didacticguidance on diagnosis, treatment and management of thiscondition. Barrett’s Espohagus gives an extensive overviewcovering epidemiology, screening, pathology, gastroenterology andsurgery. It looks at the precursor lesions leading to thedevelopment of Barrett’s epithelium, the uniquecharacteristics of Barrett’s esophagus, and the consequencesof malignant degeneration. All aspects of diagnosis, secondaryprevention, multimodality, and medical and surgical treatment areclearly explained. This is a complete guide on the latest thinking on diagnosis andtreatment of Barrett’s esophagus which can be referred toover and over again.

Advanced Molecular Targets in the Diagnosis and Treatment of Gastrointestinal Cancers

Author : Zsolt Kovacs
Publisher : Frontiers Media SA
ISBN 13 : 2832526373
Total Pages : 682 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Advanced Molecular Targets in the Diagnosis and Treatment of Gastrointestinal Cancers by : Zsolt Kovacs

Download or read book Advanced Molecular Targets in the Diagnosis and Treatment of Gastrointestinal Cancers written by Zsolt Kovacs and published by Frontiers Media SA. This book was released on 2023-06-05 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal cancers are among the most common cancer types, based on the Cancer Genome Atlas. GI cancers are within the most frequent malignancy, with almost 150.000 new cases in 2020. On one hand a big number of researches are focused on the diagnosis, new diagnostic approaches in upper and lower gastrointestinal tract cancers. On the other hand in the last 10 years several papers had been published about the possible therapeutic targets, pointing to precision and personalized medicine.

Gastric Cancer: New Insights for the Healthcare Professional: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464970041
Total Pages : 567 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Gastric Cancer: New Insights for the Healthcare Professional: 2012 Edition by :

Download or read book Gastric Cancer: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Gastric Cancer. The editors have built Gastric Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Gastric Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gastric Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases

Author : Yong Gao
Publisher : Frontiers Media SA
ISBN 13 : 283254374X
Total Pages : 468 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases by : Yong Gao

Download or read book Advances in Novel Drugs and Targets for Hepatic and Gastrointestinal Diseases written by Yong Gao and published by Frontiers Media SA. This book was released on 2024-01-29 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global incidence of gastrointestinal and hepatic diseases has been gradually increasing in recent years, which seriously threatens human health and increases the economic burden. More importantly, gastrointestinal and hepatic malignancies have the highest incidence and mortality rates among all tumors, such as liver cancer, stomach cancer, colon cancer, and pancreatic cancer. There are also non-neoplastic diseases such as viral hepatitis, cirrhosis, nonalcoholic steatohepatitis, chronic atrophic gastritis, ulcerative colitis, and reflux esophageal disease that also affect patients' quality of life. Although progress has been made in the pathogenesis of gastrointestinal and hepatic diseases, and corresponding therapeutic drugs have been also developed, the specific mechanisms of the diseases are still not revealed and there is a lack of specific drugs. In view of this, this topic aims to explore new molecular mechanisms of pathogenesis and potential therapeutic agents and pharmacological effects of gastrointestinal and hepatic diseases.

Angiogenesis & Therapeutic Targets in Cancer

Author : Malay Chatterjee
Publisher : Bentham Science Publishers
ISBN 13 : 1608050076
Total Pages : 238 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Angiogenesis & Therapeutic Targets in Cancer by : Malay Chatterjee

Download or read book Angiogenesis & Therapeutic Targets in Cancer written by Malay Chatterjee and published by Bentham Science Publishers. This book was released on 2010 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis on c

Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481665103
Total Pages : 793 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition by :

Download or read book Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gastric Cancer: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume I, 2nd edition

Download Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume I, 2nd edition PDF Online Free

Author : Muhammad Hasnat,
Publisher : Frontiers Media SA
ISBN 13 : 2832531113
Total Pages : 239 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume I, 2nd edition by : Muhammad Hasnat,

Download or read book Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume I, 2nd edition written by Muhammad Hasnat, and published by Frontiers Media SA. This book was released on 2023-07-21 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic is part of a series with: Herbal Medicines for Gastrointestinal and Hepatic Diseases - Novel Pharmacological and Toxicological approaches, Volume II Ethnopharmacology deals with the exchange of knowledge about people's use of herbal medicines and their pharmacological effects. The information related to therapeutic agents of plant origin and their toxic effects was preserved by oral tradition as well as recorded in materia medica. Many drugs that are now available on the market have been developed from this valuable information. Today, scientists that specialize in medicinal chemistry use these existing herbal drugs to develop and produce more therapeutically active agents with less toxic side effects. The gastrointestinal tract (GIT) is a multi-organ system, consisting of bacteria, and digestive enzymes that have the capacity of degrading food and other molecules. Diseases associated with this organ system include peptic ulcer, inflammatory bowel disease, gastric cancer to name a few. The liver receives seventy percent of its blood supply from the GIT via the hepatic portal vein. The disruption in the gut–liver axis is associated with liver diseases including alcohol-associated liver disease (ALD), non-alcoholic fatty liver disease (NAFLD), and autoimmune liver disease (AILD). NAFLD can cause non-alcoholic steatohepatitis, which can develop into liver cirrhosis through inflammation and fibrosis. Liver cirrhosis is categorized as an end-stage of chronic liver disease, which impairs innate immunity-related genes. Growing evidence from preclinical studies proposes that the gut–liver axis leads to targeted therapeutic modalities for various liver injuries. Therefore, therapeutic treatment of these conditions is essential to prevent progression to these more harmful late-stage diseases.

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

Author : Steve Gilbert
Publisher : Academic Press
ISBN 13 : 0128137258
Total Pages : 1055 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Information Resources in Toxicology, Volume 1: Background, Resources, and Tools by : Steve Gilbert

Download or read book Information Resources in Toxicology, Volume 1: Background, Resources, and Tools written by Steve Gilbert and published by Academic Press. This book was released on 2020-05-16 with total page 1055 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals Explores recent internet trends, web-based databases, and software tools in a section on the online environment Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 1940 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1940 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

AACR 2016: Abstracts 1-2696

Author : American Association for Cancer Research (AACR)
Publisher : CTI Meeting Technology
ISBN 13 :
Total Pages : 1617 pages
Book Rating : 4./5 ( download)

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Book Synopsis AACR 2016: Abstracts 1-2696 by : American Association for Cancer Research (AACR)

Download or read book AACR 2016: Abstracts 1-2696 written by American Association for Cancer Research (AACR) and published by CTI Meeting Technology. This book was released on 2016-03-28 with total page 1617 pages. Available in PDF, EPUB and Kindle. Book excerpt: The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.

Clinical Trials in Oncology, Third Edition

Author : Stephanie Green
Publisher : CRC Press
ISBN 13 : 1439814481
Total Pages : 266 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Clinical Trials in Oncology, Third Edition by : Stephanie Green

Download or read book Clinical Trials in Oncology, Third Edition written by Stephanie Green and published by CRC Press. This book was released on 2012-05-09 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.