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Author : E. Meyer
Publisher :
ISBN 13 : 9781468457285
Total Pages : 404 pages
Book Rating : 4.4/5 (572 download)
Download or read book Novel Approaches to the Treatment of Alzheimer's Disease written by E. Meyer and published by . This book was released on 1990-03-01 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : E. Meyer
Publisher : Springer Science & Business Media
ISBN 13 : 1468457276
Total Pages : 387 pages
Book Rating : 4.4/5 (684 download)
Download or read book Novel Approaches to the Treatment of Alzheimer’s Disease written by E. Meyer and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease afflicts up to 1 in 5 people over the age of 65 years and causes untold suffering of the patient and their family. The cause of this disease is unknown; indeed, evidence increasingly suggests that there may be multiple Alzheimer-type syndromes with different etiologies, analogous to different types of psychosis. Currently there are no means to prevent the disease, slow its progress or reverse its neurodegenerative consequences. With few exceptions, clinical trials of a variety of compounds have resulted in patient responses that are disappointing with respect to both the proportion of responders and the magnitude of the responses. Novel approaches to the treatment of Alzheimer's disease are clearly warranted. For this reason, we organized the First Suncoast Workshop on the Neurobiology of Aging in St. Petersburg, Florida, which took place from February 26-March 1, 1989. This workshop focused on novel treatments and models for Alzheimer's disease and represented a cooperative venture among academia, government and industry, both in its participants and sponsorship. The Center for the Neurobiology of Aging at the University of Florida, the National Institute on Aging and Taiho Pharmaceutical Corporation in Japan sponsored the workshop in which scientists from the North America, Europe, Japan and other parts of Asia participated.
Author : Adeboye Adejare
Publisher : Academic Press
ISBN 13 : 0128028114
Total Pages : 316 pages
Book Rating : 4.1/5 (28 download)
Download or read book Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders written by Adeboye Adejare and published by Academic Press. This book was released on 2016-09-20 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders. Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource
Author : John Zeisel
Publisher : Penguin
ISBN 13 : 9781583333358
Total Pages : 280 pages
Book Rating : 4.3/5 (333 download)
Download or read book I'm Still Here written by John Zeisel and published by Penguin. This book was released on 2009 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses ways to mentally connect with a person who has been diagnosed with Alzheimer's disease, which includes engaging individuals through the healthier parts of the brain.
Author : United Nations
Publisher :
ISBN 13 : 9789211483475
Total Pages : 44 pages
Book Rating : 4.4/5 (834 download)
Download or read book World Population Ageing 2020 Highlights written by United Nations and published by . This book was released on 2021-01-06 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the Household Living Arrangements of Older Persons 2019 Dataset, the World Population Ageing 2020 Highlights will document key patterns and trends of the household living arrangements of older persons around the world. These levels or trends will be described using indicators such as the average number of persons per household, the distribution of older persons by household type, by type of living arrangement and select characteristics of heads of household. The report will also address the impact of living arrangements of older persons on their vulnerability to the COVID-19 (coronavirus) pandemic. It will conclude with a brief discussion of global and regional trends in policies on population ageing based on the most recently available data from the United Nations Inquiry among Governments on Population and Development (2019).
Author : Joanne Koenig Coste
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0547526822
Total Pages : 177 pages
Book Rating : 4.5/5 (475 download)
Download or read book Learning to Speak Alzheimer's written by Joanne Koenig Coste and published by Houghton Mifflin Harcourt. This book was released on 2004-09-08 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to more successful communication for the millions of Americans caring for someone with dementia: “Offers a fresh approach and hope.”—NPR Revolutionizing the way we perceive and live with Alzheimer’s, Joanne Koenig Coste offers a practical approach to the emotional well-being of both patients and caregivers that emphasizes relating to patients in their own reality. Her accessible and comprehensive method, which she calls habilitation, works to enhance communication between care partners and patients and has proven successful with thousands of people living with dementia. Learning to Speak Alzheimer’s also offers hundreds of practical tips, including how to: · cope with the diagnosis and adjust to the disease’s progression · help the patient talk about the illness · face the issue of driving · make meals and bath times as pleasant as possible · adjust room design for the patient’s comfort · deal with wandering, paranoia, and aggression “A fine addition to Alzheimer's and caregiving collections.”—Library Journal (starred review) “Promises to transform not only the lives of patients but those of care providers…This book is a gift.”—Sue Levkoff, coauthor of Aging Well
Author : Khalid Iqbal
Publisher : John Wiley & Sons
ISBN 13 : 0470851740
Total Pages : 888 pages
Book Rating : 4.4/5 (78 download)
Download or read book Alzheimer's Disease written by Khalid Iqbal and published by John Wiley & Sons. This book was released on 2003-01-24 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's Disease is an ever present problem affecting millions of people around the world and, as people's average lifespan lengthens, its prevalence is set to increase. A global effort is needed to combat the disease, including research to investigate the causes, development of effective treatments and, ultimately, prevention of the disease. Published every two years, these timely books discuss the very latest research. This new volume provides a unique source of reference to the important work being done in this field, it gives academics and clinicians an opportunity to learn about cutting edge developments and covers all aspects of Alzheimer's Disease, including diagnosis, clinical course, epidemiological course and therapeutics and disease mechanisms. Alzheimer's Disease: Advances in Etiology, Pathogenesis and Therapeutics will provide essential information for basic and clinical researchers in Alzheimer's Disease and other dementias as well as for those who care for patients.
Author : Lisa Scott
Publisher :
ISBN 13 : 9781639874002
Total Pages : 0 pages
Book Rating : 4.8/5 (74 download)
Download or read book Novel Biomarkers in Alzheimer's Disease written by Lisa Scott and published by . This book was released on 2022-09-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurochemical indicators which help in the assessment of risk or the presence of Alzheimer's disease are known as Alzheimer's disease biomarkers. They help in an early diagnosis as well as tracking the progress of the disease in a reliable manner. The analysis of biomarkers becomes vital to the management of this disease since the neuropathologic changes occur years before the symptoms are seen. The most important biomarker used for the detection of Alzheimer's disease is amyloid beta. One of the novel approaches towards research on Alzheimer's disease is the usage of autoantibody. These can be used as both biomarkers and for future treatment. This book elucidates the concepts and innovative models around prospective developments with respect to novel biomarkers in Alzheimer's disease. It will also provide interesting topics for research which interested readers can take up. Researchers and students in this field will be assisted by this book.
Author : Gayatri Devi
Publisher : Thorndike Press Large Print
ISBN 13 : 9781432846473
Total Pages : 574 pages
Book Rating : 4.8/5 (464 download)
Download or read book The Spectrum of Hope written by Gayatri Devi and published by Thorndike Press Large Print. This book was released on 2018 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: "By defining Alzheimer's Disease as a spectrum disorder---like autism, it affects different people differently---Dr. Gayatri Devi offers new hope for its millions of sufferers. A neurologist who's been specializing in dementia and memory loss for more than 20 years, Dr. Devi shares the stories of her patients in the kind of narrative medical writing that grips the reader, humanizes the science, and offers equal parts practical wisdom and advice. She explains the importance of an early diagnosis; drugs and therapies that can help manage the disease; and how to cope, from maintaining independence to the best ways to fight depression and apathy. There are chapters on sexuality, genetics, communication, even staying on the job---because through her practice, Dr. Devi knows that the majority of Alzheimer's patients continue to live and work in their communities. They babysit the grandkids, drive to the store (or own the store), serve their clients, or otherwise live fulfilling lives."--Back cover.
Author : Jeffrey Cummings
Publisher : Cambridge University Press
ISBN 13 : 1108838669
Total Pages : 575 pages
Book Rating : 4.1/5 (88 download)
Download or read book Alzheimer's Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author : Thimmaiah Govindaraju
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162740
Total Pages : 695 pages
Book Rating : 4.8/5 (391 download)
Download or read book Alzheimer's Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.
Author : Andrew E. Budson, MD
Publisher : Elsevier Health Sciences
ISBN 13 : 0323286615
Total Pages : 293 pages
Book Rating : 4.3/5 (232 download)
Download or read book Memory Loss, Alzheimer's Disease, and Dementia written by Andrew E. Budson, MD and published by Elsevier Health Sciences. This book was released on 2015-07-23 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now presented in full color, this updated edition of Memory Loss, Alzheimer's Disease, and Dementia is designed as a practical guide for clinicians that delivers the latest treatment approaches and research findings for dementia and related illnesses. Drs. Budson and Solomon - both key leaders in the field - cover the essentials of physical and cognitive examinations and laboratory and imaging studies, giving you the tools you need to consistently make accurate diagnoses in this rapidly growing area. Access in-depth coverage of clinically useful diagnostic tests and the latest treatment approaches. Case studies have been incorporated into the chapters and facilitate the management of both common and uncommon conditions. Comprehensive coverage of hot topics such as chronic traumatic encephalopathy, in addition to new criteria on vascular dementia and vascular cognitive impairment. Includes new National Institute on Aging-Alzheimer's Association and DSM-5 criteria for Alzheimer's Disease and Mild Cognitive Impairment. Learn how to use new diagnostic tests, such as the amyloid imaging scans florbetapir (Amyvid), flutemetamol (Vizamyl), and florbetaben (Neuraceq), which can display amyloid plaques in the living brains of patients. Updated case studies, many complete with videos illustrating common tests, clinical signs, and diagnostic features, are now incorporated into the main text as clinical vignettes for all major disorders. Brand-new chapters on how to approach the differential diagnosis and on primary progressive aphasia. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices. A practical guide mirroring clinical workflow intended to be used as a tool for accurately diagnosing dementia for all clinicians. Includes case studies and tests.
Author : George Perry
Publisher :
ISBN 13 : 9781614998754
Total Pages : 0 pages
Book Rating : 4.9/5 (987 download)
Download or read book Alzheimer's Disease written by George Perry and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's Disease: New Beginnings focuses on the future promise for therapeutic breakthroughs in light of notable clinical trial failures. The volume editors used a combination of scientometric evaluations to determine the most promising new approaches as well as soliciting insights from leaders in each of the major areas of Alzheimer's disease research. By combining these two approaches, they recruited authors from the entire outlook spectrum, from those who feel an elusive breakthrough might still be a few, well-placed tweaks away to those who feel that they are launching entirely new investigative paradigms. These scholars present an open-eyed path forward. Now is the most exciting period in this field as old dogmas make way for new insights, from new approaches to clinical trials, improved biomarker-based diagnostics, population-based studies, prevention, metabolism, to further refinement of the role of inflammation, genetics, tau, and amyloid-β.
Author : Bradford C. Dickerson
Publisher : Oxford University Press, USA
ISBN 13 : 0199928452
Total Pages : 705 pages
Book Rating : 4.1/5 (999 download)
Download or read book Dementia written by Bradford C. Dickerson and published by Oxford University Press, USA. This book was released on 2014 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a clinically-oriented text written by internationally-recognized experts. The work's three major sections establish the neuroanatomical and cognitive framework underlying disorders of cognition, provide fundamental as well as cutting-edge material covering specific diseases associated with dementia, and discuss approaches to the diagnosis and treatment of dementing illnesses.
Author : Dale Bredesen
Publisher : Penguin
ISBN 13 : 0735216207
Total Pages : 322 pages
Book Rating : 4.7/5 (352 download)
Download or read book The End of Alzheimer's written by Dale Bredesen and published by Penguin. This book was released on 2017-08-22 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.
Author : Edwin M. Meyer
Publisher : Springer Science & Business Media
ISBN 13 : 1461534321
Total Pages : 526 pages
Book Rating : 4.4/5 (615 download)
Download or read book Treatment of Dementias written by Edwin M. Meyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease is one the foremost health problems facing every society fortunate enough to attain a level of medical care that ensures an average lifespan of over 70 years of age. The cause of the disease remains unknown, and no single therapeutic approach has yet been found highly efficacious. Indeed, as the complexity of its effects on brain neuronal systems becomes elucidated, the concept emerges that Alzheimer's disease may be an umbrella term for multiple Alzheimer's-type syndromes that can be differentiated based on etiology (hereditary versus sporadic), neurochemical deficits, and extent of pathology. Whether one or more disease processes is involved, it seems increasingly unlikely that any single drug will provide efficacious relief across the broad spectrum of symptoms reflected in large subject populations. Rational therapeutic approaches may yield long term amelioration of many symptoms in selected groups of patients; and individual symptoms may be ameliorated in larger populations. Multiple approaches may be combined to optimize therapeutic effects. For example, a variety of approaches remain focused on restoration of cholinergic neurodegeneration and enhancing cholinergic neurotransmission, whereas other approaches attempt to retard the of the brain that occurs during Alzheimer's disease. Chapters cover continuous degeneration topics from growth factor secretion of proteases, which could modify amyloid processing, to neuronal gene delivery using viral vectors. The breadth and thoroughness of the chapters truly embrace a broad spectrurn of models, pathological mechanisms and therapeutic approaches.
Author : William Rodman Shankle
Publisher : Penguin
ISBN 13 : 9780399531606
Total Pages : 312 pages
Book Rating : 4.5/5 (316 download)
Download or read book Preventing Alzheimer's written by William Rodman Shankle and published by Penguin. This book was released on 2005-06-07 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. William Rodman Shankle and Daniel G. Amen reveal the latest research and treatment methods for preventing, delaying, and treating the devastation of Alzheimer's disease.
