Novel Approaches To Colorectal Cancer

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Novel Approaches to Colorectal Cancer

Author :
Publisher : Academic Press
ISBN 13 : 0128240792
Total Pages : 486 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Novel Approaches to Colorectal Cancer by :

Download or read book Novel Approaches to Colorectal Cancer written by and published by Academic Press. This book was released on 2021-06-18 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality. Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research Offers outstanding and original reviews on colorectal cancer research Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer

Colorectal Cancer

Author : Valeria Barresi
Publisher :
ISBN 13 : 9783036529233
Total Pages : 284 pages
Book Rating : 4.5/5 (292 download)

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Book Synopsis Colorectal Cancer by : Valeria Barresi

Download or read book Colorectal Cancer written by Valeria Barresi and published by . This book was released on 2022 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is one of the most common malignancies worldwide, and the pathogenesis of this neoplasm is probably one of the most studied. The knowledge obtained over time has led to the development of screening and early diagnosis systems, allowing a significant reduction in the incidence of this neoplasm. However, what is currently known probably represents only the tip of the iceberg of the biology of this tumor. It was recently shown that the gut microbiota may contribute to colorectal cancerogenesis. In addition, several novel targeted therapies are now applied to patients with colorectal carcinoma. Nonetheless, several questions are still unanswered. Could the modulation of the gut microbiota modify the risk of tumor progression or the efficacy of therapies? Are there any predictive biomarkers of the risk of tumor progression or the efficacy of target therapies? Is metastatic colorectal cancer one or more diseases? This book collects a series of scientific articles reflecting part of the state of the art regarding colorectal cancer, seeking to answer these questions.

Theranostics Approaches to Gastric and Colon Cancer

Author : Ganji Seeta Rama Raju
Publisher : Springer Nature
ISBN 13 : 9811520178
Total Pages : 261 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Theranostics Approaches to Gastric and Colon Cancer by : Ganji Seeta Rama Raju

Download or read book Theranostics Approaches to Gastric and Colon Cancer written by Ganji Seeta Rama Raju and published by Springer Nature. This book was released on 2020-03-04 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Molecular Pathogenesis of Colorectal Cancer

Author : Kevin M. Haigis, Ph.D.
Publisher : Springer Science & Business Media
ISBN 13 : 146148412X
Total Pages : 316 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Molecular Pathogenesis of Colorectal Cancer by : Kevin M. Haigis, Ph.D.

Download or read book Molecular Pathogenesis of Colorectal Cancer written by Kevin M. Haigis, Ph.D. and published by Springer Science & Business Media. This book was released on 2013-10-02 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.

Colon Cancer Diagnosis and Therapy

Author : Ganji Purnachandra Nagaraju
Publisher : Springer Nature
ISBN 13 : 3030633691
Total Pages : 374 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Colon Cancer Diagnosis and Therapy by : Ganji Purnachandra Nagaraju

Download or read book Colon Cancer Diagnosis and Therapy written by Ganji Purnachandra Nagaraju and published by Springer Nature. This book was released on 2021-06-10 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the first of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage also addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutic, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

Novel Approaches to Selective Treatments of Human Solid Tumors

Author : Youcef M. Rustum
Publisher : Springer Science & Business Media
ISBN 13 : 1461524881
Total Pages : 306 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Novel Approaches to Selective Treatments of Human Solid Tumors by : Youcef M. Rustum

Download or read book Novel Approaches to Selective Treatments of Human Solid Tumors written by Youcef M. Rustum and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Colorectal Cancer

Author : Kees Welvaart
Publisher : Springer Science & Business Media
ISBN 13 : 9789060214657
Total Pages : 314 pages
Book Rating : 4.2/5 (146 download)

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Book Synopsis Colorectal Cancer by : Kees Welvaart

Download or read book Colorectal Cancer written by Kees Welvaart and published by Springer Science & Business Media. This book was released on 1980-10-31 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the proceedings of a successful Boerhaave International Symposium on colorectal cancer held at the University of Leiden, 6-9 June, 1979. I would like to offer grateful thanks to the eminent clinicians and scientists who contributed both to the Symposium and to this book. Colorectal cancer is a very common form of malignancy, particularly in the Western world, and there have been a number of recent developments in the management of this condition. This book has attempted to collate informa tion on the current methods of investigation and treatment and I believe that it will prove valuable to all those interested in oncology. The contents range widely, covering the entire field from epidemiology through screening methods, diagnostic approaches and therapy of both primary and secondary disease. Perhaps the most outstanding new areas discussed and reflected in the proceedings are the possible range and scope of screening techniques, the new possibilities both in treatment and in endoscopic surgery now available as a result of developments in fibre-optic endoscopy, and new approaches and important parameters in staging of the disease.

Colon Cancer Diagnosis and Therapy

Author : Naveen Kumar Vishvakarma
Publisher : Springer Nature
ISBN 13 : 3030646688
Total Pages : 453 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Colon Cancer Diagnosis and Therapy by : Naveen Kumar Vishvakarma

Download or read book Colon Cancer Diagnosis and Therapy written by Naveen Kumar Vishvakarma and published by Springer Nature. This book was released on 2021-06-04 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

Novel Approaches to Target the Immune System in Gastrointestinal Cancers

Author : Gianluigi Giannelli
Publisher : Frontiers Media SA
ISBN 13 : 288974261X
Total Pages : 151 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Novel Approaches to Target the Immune System in Gastrointestinal Cancers by : Gianluigi Giannelli

Download or read book Novel Approaches to Target the Immune System in Gastrointestinal Cancers written by Gianluigi Giannelli and published by Frontiers Media SA. This book was released on 2022-01-31 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Foundations of Colorectal Cancer

Author : Alejandro Pazos Sierra
Publisher : Academic Press
ISBN 13 : 0323885713
Total Pages : 672 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Foundations of Colorectal Cancer by : Alejandro Pazos Sierra

Download or read book Foundations of Colorectal Cancer written by Alejandro Pazos Sierra and published by Academic Press. This book was released on 2021-10-28 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundations of Colorectal Cancer provides a holistic and comprehensive dive into colorectal cancer, discussing the contributions of each discipline that studies it, allowing its understanding from the most demographic and ethical facts, to the treatment process, its varieties and genetic background. Written by experts in diverse areas such as cancer research, oncology, genetics, biochemistry, psychology, social sciences, bioinformatics and palliative care, the book brings real-world experiences to help readers with any challenge they may face when dealing with patients or during their research workflow. The content is split into nine sections: Clinical manifestations and disease detection, covering primary and secondary prevention, and the role of primary care; Diagnosis and staging, discussing endoscopy, colonoscopy, molecular pathology, and anatomopathological diagnosis; Treatment, including endoscopic, surgical, radiological, and postoperative approaches; Molecular and biological mechanisms, with the role of intestinal microbiota, stem cells and signaling pathways; New diagnostic methods, encompassing biomarkers and bioinformatics tools for research; Biobanks, with an overview of their regulations and importance in the research; Epidemiological studies, focusing on incidence and mortality globally and by regions; Hereditary colorectal cancer, differentiating nonpolyposis and polyposis types; and Addressing the consequences of colorectal cancer, covering psychological effects, nutrition and ethical issues. Provides a multidisciplinary approach with a holistic view of colorectal cancer, ranging from basic science to population studies, with its social and environmental influences and impacts, interpreting the disease as a medical, chemical, physical, microbial, psychological, and social condition Written by a diverse group of specialists with complementary expertise, including oncologists, radiologists, biochemists, surgeons, psychologists, social workers and clinicians, all members of the Galician Research Network of Colorectal Cancer (REGICC) with vast collaboration experience to bring comprehensive knowledge on the subject Encompasses reliable information suitable for different workers within the healthcare sector and research community dedicated to colorectal cancer, from clinicians and healthcare providers, researchers on several aspects of cancer, to bioinformaticians who deal with health data Includes many case studies throughout the chapters discussed by specialists with high scientific accuracy and didactic value, in order to clearly and precisely share their professional experience on the subject with readers

Novel therapeutic approaches for gastrointestinal malignancies

Author : Ganji Purnachandra Nagaraju
Publisher : Springer Nature
ISBN 13 : 9811554714
Total Pages : 259 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Novel therapeutic approaches for gastrointestinal malignancies by : Ganji Purnachandra Nagaraju

Download or read book Novel therapeutic approaches for gastrointestinal malignancies written by Ganji Purnachandra Nagaraju and published by Springer Nature. This book was released on 2020-10-01 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.

The ASCRS Textbook of Colon and Rectal Surgery

Author : Scott R. Steele
Publisher : Springer
ISBN 13 : 3319259709
Total Pages : 1269 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis The ASCRS Textbook of Colon and Rectal Surgery by : Scott R. Steele

Download or read book The ASCRS Textbook of Colon and Rectal Surgery written by Scott R. Steele and published by Springer. This book was released on 2016-03-24 with total page 1269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition text provides a completely revised and updated new version of this unique, modern, practical text that covers the strategic evaluation, specific approaches, and detailed management techniques utilized by expert colorectal surgeons caring for patients with complex problems–whether they result from underlying colorectal disease or from complications arising from previous surgical therapy. The format follows that of both a “how to” manual as well as an algorithm-based guide to allow the reader to understand the thought process behind the proposed treatment strategy. By making use of evidence-based recommendations, each chapter includes not only background information and diagnostic/therapeutic guidelines, but also provides a narrative by the author on his/her operative technical details and perioperative “tips and tricks” that they utilize in the management of these complex surgical challenges. Distinctive to this book, is the reliance on experts in the field including past presidents of the ASCRS, as well as multiple other national and internationally recognized surgeons, to lend their personal insight into situations where data may be more sparse, but individual and collective experience is paramount to making sound decisions and thereby optimizing patient outcomes. The text includes chapters on the assessment of risk and methods utilized to minimize perioperative complications. In addition, it incorporates sections covering the medical and surgical therapies for abdominal, pelvic and anorectal disease. Moreover, the technical challenges of managing complications resulting from the original or subsequent operations is addressed. The underlying focus throughout the text is on providing pragmatic and understandable solutions that can be readily implemented by surgeons of varying experience to successfully treat complex colorectal problems. However, it also goes beyond the technical aspects of colorectal surgery and includes special sections highlighting the essence of a surgeon; covering aspects involving the medical-legal, ethical, and economic challenges confronting surgeons. Throughout the text, each author provides an ongoing narrative of his/her individual surgical techniques along with illustrations and diagrams to “personally” take the reader through the crucial steps of the procedure, and key points of patient care inherent to that topic. Additionally, where appropriate, links to online videos give the reader an up-front look into technical aspects of colorectal surgery.

The ASCRS Manual of Colon and Rectal Surgery

Author : David E. Beck
Publisher : Springer Science & Business Media
ISBN 13 : 0387734406
Total Pages : 1042 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis The ASCRS Manual of Colon and Rectal Surgery by : David E. Beck

Download or read book The ASCRS Manual of Colon and Rectal Surgery written by David E. Beck and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 1042 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ASCRS Textbook of Surgery of the Colon and Rectum offers a comprehensive textbook designed to provide state of the art information to residents in training and fully trained surgeons seeking recertification. The textbook also supports the mission of the ASCRS to be the world’s authority on colon and rectal disease. The combination of junior and senior authors selected from the membership of the ASCRS for each chapter will provide a comprehensive summary of each topic and allow the touch of experience to focus and temper the material. This approach should provide the reader with a very open minded, evidence based approach to all aspects of colorectal disease. Derived from the textbook, The ASCRS Manual of Surgery of the Colon and Rectum offers a “hands on” version of the textbook, written with the same comprehensive, evidence-based approach but distilled to the clinical essentials. In a handy pocket format, readers will find the bread and butter information for the broad spectrum of practice. In a consistent style, each chapter outlines the condition or procedure being discussed in a concise outline format – easy to read, appropriately illustrated and referenced.

Colorectal Cancer

Author : Jindong Chen
Publisher : BoD – Books on Demand
ISBN 13 : 1789231000
Total Pages : 130 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Colorectal Cancer by : Jindong Chen

Download or read book Colorectal Cancer written by Jindong Chen and published by BoD – Books on Demand. This book was released on 2018-05-16 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: With international experts sharing their experience and knowledge on these different aspects in the management of colorectal cancer, this book has this opportunity to offer all physicians treating colorectal cancer, as well as researchers, updated information concerning the biology, diagnosis, screening, and treatment of colorectal carcinoma. This book provides a detailed evaluation of diagnostic modalities, in-depth analysis of screening for colorectal cancer, recent advances in treatment, and principles and trends in the management of colorectal cancer. This updated knowledge will be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer. In addition, readers such as related physicians, researchers, and colorectal cancer patients are potential beneficiaries of this book.

Colorectal Cancer

Author : Valeria Barresi
Publisher :
ISBN 13 : 9783036529233
Total Pages : 284 pages
Book Rating : 4.5/5 (292 download)

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Book Synopsis Colorectal Cancer by : Valeria Barresi

Metastatic Diseases

Author : Sandeep Arora
Publisher : CRC Press
ISBN 13 : 100006493X
Total Pages : 342 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Metastatic Diseases by : Sandeep Arora

Download or read book Metastatic Diseases written by Sandeep Arora and published by CRC Press. This book was released on 2021-11-17 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This insightful volume opens new horizons for exploring modern therapeutic entities and emerging targets for combating the deadly disease of cancer. The authors provide a review of cancer along with descriptions of its molecular level mechanisms and emphasize the role of promising new therapies, including herbal therapies, that can be utilized for the treatment of metastatic diseases. The chapters look at specific approaches that have been researched and developed and that have almost reached the standardization stage, such as intracellular mechanisms, particularly phosphoprotein-enriched astrocytes and transthyretin proteins; CXCR4; autophagy-inhibiting drugs; spatiotemporal genetic analysis; tyrosine kinase inhibitors; and more. Also considered are advances in diagnostic systems like intra vital microscopy and molecular imaging.