Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Download Non Viral Gene Therapy Volume Ii full books in PDF, epub, and Kindle. Read online Non Viral Gene Therapy Volume Ii ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Author :
Publisher :
ISBN 13 : 9781978915213
Total Pages : 0 pages
Book Rating : 4.9/5 (152 download)
Download or read book Non-viral gene therapy written by and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Harvey Summers
Publisher :
ISBN 13 : 9781632422927
Total Pages : 0 pages
Book Rating : 4.4/5 (229 download)
Download or read book Non-Viral Gene Therapy: Volume II written by Harvey Summers and published by . This book was released on 2015-02-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with current developments in the study of gene delivery structures. With interdisciplinary inputs in gene delivery, the book covers a number of aspects in the gene therapy enhancement, covering nanoparticles for gene therapy, nanomedicine based approaches to cancer diagnosis and therapy. This book will assist experts in comprehending the fundamental knowledge of gene delivery vehicles, DNA molecular biology and DNA management.
Author : Leaf Huang
Publisher : Elsevier
ISBN 13 : 0080456138
Total Pages : 398 pages
Book Rating : 4.0/5 (84 download)
Download or read book Nonviral Vectors for Gene Therapy, Part 2 written by Leaf Huang and published by Elsevier. This book was released on 2005-08-01 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.
Author : Ravin Narain
Publisher : Woodhead Publishing
ISBN 13 : 0081005210
Total Pages : 303 pages
Book Rating : 4.0/5 (81 download)
Download or read book Polymers and Nanomaterials for Gene Therapy written by Ravin Narain and published by Woodhead Publishing. This book was released on 2016-01-09 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. Explores current challenges in the research of genetic diseases Discusses polymers for gene therapy and their function in designing advanced materials Provides examples of organic and inorganic nanomaterials for gene therapy Includes labeling, targeting, and assays Looks at characterization, physico-(bio)chemical properties, and applications
Author : Mark A. Findeis
Publisher : Springer Science & Business Media
ISBN 13 : 1592591396
Total Pages : 399 pages
Book Rating : 4.5/5 (925 download)
Download or read book Nonviral Vectors for Gene Therapy written by Mark A. Findeis and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this volume of Methods in Molecular Medicine is to set forth examples of the great variety of techniques and applications that are now emerging in the field of nonviral gene therapy. The book emphasizes not only specific approaches to gene delivery but, in particular, the best current me- ods to prepare, handle, and characterize gene delivery agents. These topics are of very broad importance since gene therapy evolves from its mostly ac- emy-based experimental and clinical research to the ever increasing number of industry-driven programs directed toward commercial development. S- cessful introduction of nonviral gene therapy agents into the clinic should be expected to require rigorous manufacturing and analytical methods that readily meet the regulatory guidelines under which new drug candidates are reviewed for marketing approval. Exactly what those guidelines will prove to be c- tainly depends on the established guidelines for review of both biological and chemical therapeutics. Additionally, many new techniques are being devised and applied to gene therapy research; these techniques will be instrumental in developing and characterizing successful gene delivery agents. Nonviral Vectors for Gene Therapy: Methods and Protocols has two main sections. To start with, there is a series of chapters on specific protocols for the synthesis, characterization, and application of gene delivery agents. S- eral chapters address the topic of materials to bind with DNA to form the compact condensed phases that facilitate cellular delivery.
Author : Fredric P. Manfredsson
Publisher :
ISBN 13 : 9781493990658
Total Pages : 328 pages
Book Rating : 4.9/5 (96 download)
Download or read book Viral Vectors for Gene Therapy written by Fredric P. Manfredsson and published by . This book was released on 2019 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses protocols, ranging from vector production to delivery methods, used to execute gene therapy applications. Chapters are divided into four parts, and cover topics such as design, construction, and application of transcription activation-like effectors; multi-modal production of adeno-associated virus; construction of oncolytic herpes simplex virus; AAV-mediated gene delivery to the mouse liver; and intrathecal delivery of gene therapeutics by direct lumbar puncture in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Viral Vectors for Gene Therapy: Methods and Protocols is a valuable resource for researchers, clinicians, and students looking to utilize viral vectors in gene therapy experiments.
Author :
Publisher :
ISBN 13 : 9781978915206
Total Pages : 0 pages
Book Rating : 4.9/5 (152 download)
Download or read book Non-viral gene therapy written by and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David T. Curiel
Publisher : Academic Press
ISBN 13 : 0128005106
Total Pages : 870 pages
Book Rating : 4.1/5 (28 download)
Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press. This book was released on 2016-03-10 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement Demonstrates noninvasive imaging of adenovirus-mediated gene transfer Discusses utility of adenoviral vectors in animal disease models Considers Federal Drug Administration regulations for human clinical trials
Author : Leaf Huang
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (68 download)
Download or read book Non-viral Vectors for Gene Therapy: (v. 53). Recent advances in non-viral gene delivery written by Leaf Huang and published by . This book was released on 2005 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Harvey Summers
Publisher :
ISBN 13 : 9781632422910
Total Pages : 0 pages
Book Rating : 4.4/5 (229 download)
Download or read book Non-Viral Gene Therapy: Volume I written by Harvey Summers and published by . This book was released on 2015-02-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with current developments in the study of gene delivery structures. With interdisciplinary inputs in gene delivery, the book covers a number of aspects in the gene therapy enhancement, different gene delivery systems, techniques to improve delivery, materials with alteration and multifunction for the tumor or tissue targeting. This book will assist experts in comprehending the fundamental knowledge of gene delivery vehicles, DNA molecular biology and DNA management.
Author : Manzoor M. Khan
Publisher : Springer Science & Business Media
ISBN 13 : 0387779760
Total Pages : 275 pages
Book Rating : 4.3/5 (877 download)
Download or read book Immunopharmacology written by Manzoor M. Khan and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decades, with the introduction of the recombinant DNA, hybridoma and transgenic technologies there has been an exponential evolution in understanding the pathogenesis, diagnosis and treatment of a large number of human diseases. The technologies are evident with the development of cytokines and monoclonal antibodies as therapeutic agents and the techniques used in gene therapy. Immunopharmacology is that area of biomedical sciences where immunology, pharmacology and pathology overlap. It concerns the pharmacological approach to the immune response in physiological as well as pathological events. This goals and objectives of this textbook are to emphasize the developments in immunology and pharmacology as they relate to the modulation of immune response. The information includes the pharmacology of cytokines, monoclonal antibodies, mechanism of action of immune-suppressive agents and their relevance in tissue transplantation, therapeutic strategies for the treatment of AIDS and the techniques employed in gene therapy. The book is intended for health care professional students and graduate students in pharmacology and immunology.
Author :
Publisher : Academic Press
ISBN 13 : 0128024704
Total Pages : 297 pages
Book Rating : 4.1/5 (28 download)
Download or read book Nonviral Vectors for Gene Therapy written by and published by Academic Press. This book was released on 2015-01-23 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. Advances in Genetics continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Includes methods for testing with ethical, legal, and social implications Critically analyzes future directions Written and edited by recognized leaders in the field
Author : Patrick Arbuthnot
Publisher : Academic Press
ISBN 13 : 0124114520
Total Pages : 391 pages
Book Rating : 4.1/5 (241 download)
Download or read book Gene Therapy for Viral Infections written by Patrick Arbuthnot and published by Academic Press. This book was released on 2015-06-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections Bridges the gap between the basic science and the important medical applications of this technology Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs Arms the reader with the cutting-edge information needed to stay abreast of this developing field
Author : Kazunari Taira
Publisher : Springer Science & Business Media
ISBN 13 : 4431278796
Total Pages : 494 pages
Book Rating : 4.4/5 (312 download)
Download or read book Non-viral Gene Therapy written by Kazunari Taira and published by Springer Science & Business Media. This book was released on 2006-03-20 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents information on non-viral gene-delivery techniques, covering a spectrum of disciplines that include chemistry, molecular biology, cell biology, and pharmacokinetics. This work is useful to researchers and engineers in genetic engineering, molecular medicine, biochemical engineering, and biotechnology.
Author : Joseph LeDoux
Publisher : Humana Press
ISBN 13 : 9781603272476
Total Pages : 336 pages
Book Rating : 4.2/5 (724 download)
Download or read book Gene Therapy Protocols written by Joseph LeDoux and published by Humana Press. This book was released on 2008-04-24 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Gene Therapy Protocols, Volumes 1 and 2, internationally recognized investigators describe cutting-edge laboratory techniques for the study of Production and In Vivo Applications of Gene Transfer Vectors (Volume 1) and Design and Characterization of Gene Transfer Vectors (Volume 2). In this second volume, readers will find a comprehensive resource of current and emerging methods for the processing and characterization of viral and non-viral gene transfer vectors.
Author : Malcolm Brenner
Publisher : John Wiley & Sons
ISBN 13 : 1118501659
Total Pages : 262 pages
Book Rating : 4.1/5 (185 download)
Download or read book Cancer Gene Therapy by Viral and Non-viral Vectors written by Malcolm Brenner and published by John Wiley & Sons. This book was released on 2014-02-25 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides expert, state-of-the-art insight into the current progress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era of personalized or precision medicine. No longer a one-size-fits-all approach, the treatment of cancer is now based on an understanding of underlying biologic mechanisms and is increasingly being tailored to the molecular specificity of a tumor. This book provides a comprehensive overview of the pertinent molecular discoveries in the cancer field and explains how these are being used for gene-based cancer therapies. Designed as a volume in the Translational Oncology book series, Cancer Gene Therapy by Viral and Non-viral Vectors deals with the practice of gene-therapy, with reference to vectors for gene expression and gene transfer, as well as viral therapy. It covers the history and current and future applications of gene transfer in cancer, and provides expert insight on the progress of viral and non-viral gene therapy with regard to delivery system, vector design, potential therapeutic genes, and principles and regulations for cancer gene therapy. Presented in three parts, Cancer Gene Therapy by Viral and Non-viral Vectors covers: Delivery Systems • Translational Cancer Research: Gene Therapy by Viral and Non-viral Vectors • Retroviruses for Cancer Therapy • DNA Plasmids for Non-viral Gene Therapy of Cancer • Cancer Therapy with RNAi delivered by Non-viral Membrane/Core Nanoparticles Targeted Expression • Cancer Gene Therapy by Tissue-specific and Cancer-targeting Promptors • MicroRNAs as Drugs and Drug Targets in Cancer Principles of Clinical Trials in Gene Therapy • Regulatory issues for Manufacturers of Viral Vectors and Vector-transduced Cells for Phase I/II Trials • US Regulations Governing Clinical Trials in Gene Therapy • Remaining Obstacles to the Success of Cancer Gene Therapy Focusing on speeding the process in clinical cancer care by bringing therapies as quickly as possible from bench to bedside, Cancer Gene Therapy by Viral and Non-viral Vectors is an absolutely vital book for physicians, clinicians, researchers, and students involved in this area of medicine.
Author : Leaf Huang
Publisher : Gulf Professional Publishing
ISBN 13 : 9780120176533
Total Pages : 412 pages
Book Rating : 4.1/5 (765 download)
Download or read book Non-viral Vectors for Gene Therapy written by Leaf Huang and published by Gulf Professional Publishing. This book was released on 2005 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.
