Nitric Oxide Cytochromes P450 And Sexual Steroid Hormones

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Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones

Author : Jack R. Jr. Lancaster
Publisher : Springer Science & Business Media
ISBN 13 : 3662035030
Total Pages : 351 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones by : Jack R. Jr. Lancaster

Download or read book Nitric Oxide, Cytochromes P450, and Sexual Steroid Hormones written by Jack R. Jr. Lancaster and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of mammalian nitric oxide (NO) synthesis from L-arginine has led to a profound increase in our understanding of basic physiological and pathophysiological processes. The NO-dependent regulation of steroidogenic cytochromes P450, such as aromotase, and local, tissue-specific regulation of NOS isoform expression by sexual steroid hormones, such as estrogen and progesterone, promises to provide new insights into the regulation of endocrinological processes. Research on the interaction between the NO and sexual steroid systems are likely to lead to novel therapeutic concepts for use in diseases associated with perturbations of the endocrine system.

Nitric Oxide in Bone and Joint Disease

Author : Mika V. J. Hukkanen
Publisher : Cambridge University Press
ISBN 13 : 9780521592208
Total Pages : 216 pages
Book Rating : 4.5/5 (922 download)

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Book Synopsis Nitric Oxide in Bone and Joint Disease by : Mika V. J. Hukkanen

Download or read book Nitric Oxide in Bone and Joint Disease written by Mika V. J. Hukkanen and published by Cambridge University Press. This book was released on 1998-10-15 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide research has emerged as one of the most important areas in bone and joint diseases. First published in 1998, this book draws together knowledge on the actions of this mediator and its role in such common diseases as arthritis and osteoporosis. It introduces the basic biology and biochemistry of nitric oxide, the immune response and bone biology. It reviews in depth the facts we know today and the future promise of this exciting area of research. The book will give scientists and clinicians a unique insight into this increasingly important area. It also emphasises potential treatments which exploit our understanding of the role of nitric oxide in bone and joint disease.

Signal Transduction and the Gasotransmitters

Author : Rui Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1592598064
Total Pages : 372 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Signal Transduction and the Gasotransmitters by : Rui Wang

Download or read book Signal Transduction and the Gasotransmitters written by Rui Wang and published by Springer Science & Business Media. This book was released on 2004-06-11 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gasotransmitters-principally nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)-are endogenous signaling molecules that play a significant role in the biomedical, clinical, and health sciences, as well as in population health studies. In Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine, a panel of distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing their signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels. Included in the array of different mechanisms for the interaction of NO, CO, and H2S are channel phosphorylation, S-nitrosylation, carboxylation, sulfuration, and altered cellular redox status. The authors also offer guidance and suggestions for exploring and further characterizing other still unknown gasotransmitters. Authoritative and comprehensive, Signal Transduction and the Gasotransmitters: NO, CO, and H2S in Biology and Medicine offers clinical scientists and physicians not only a deeper understanding, but also a cutting-edge review, of the critically important field of gasotransmitter biology and medicine.

Omega-3 Fatty Acids

Author : Mahabaleshwar V. Hegde
Publisher : Humana Press
ISBN 13 : 331940458X
Total Pages : 610 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Omega-3 Fatty Acids by : Mahabaleshwar V. Hegde

Download or read book Omega-3 Fatty Acids written by Mahabaleshwar V. Hegde and published by Humana Press. This book was released on 2016-09-15 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume argues for the importance of essential nutrients in our diet. Over the last two decades there has been an explosion of research on the relationship of Omega-3 fatty acids and the importance of antioxidants to human health. Expert authors discuss the importance of a diet rich in Omega-3 Fatty acids for successful human growth and development and for the prevention of disease. Chapters highlight their contribution to the prevention and amelioration of a wide range of conditions such as heart disease, diabetes, arthritis, cancer, obesity, mental health and bone health. An indispensable text designed for nutritionists, dietitians, clinicians and health related professionals, Omega-3 Fatty Acids: Keys to Nutritional Health presents a comprehensive assessment of the current knowledge about the nutritional effects of Omega-3 fatty acids and their delivery in foods.

Free Radicals and Inflammation

Author : Paul G. Winyard
Publisher : Springer
ISBN 13 : 3034884826
Total Pages : 260 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Free Radicals and Inflammation by : Paul G. Winyard

Download or read book Free Radicals and Inflammation written by Paul G. Winyard and published by Springer. This book was released on 2013-03-11 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: As in so many fields of scientific endeavour following the molecular biology revo lution, our knowledge of the role of radicals not only in pathological states, but in basic physiology has developed exponentially. Indeed, our evolving concepts have, like so many political parties, been forced into dramatic "V-turns" and contortions. Within our working lives, we have had to debate whether radicals made any con tribution to any pathology, whilst now it is difficult not to entertain the view that every physiological process is pivotally controlled by exquisitely sensitive radical reactions. Inflammation is, of course, an example of pathology evolving from physiology, and in this book we have called upon both scientists and clinicians who have research interests in the complex switching mechanisms that sustain these transi tions. The book as a whole explores, from a physiological standpoint, how deter ministic radical systems sensitive to their initial conditions can interdigitate, iterate and feed back to control diverse cellular processes that create the inflammatory response. Whilst systems such as these to a mathematician would provide the basis for a chaotic response, one is forced to marvel how, for all stages of an inflammatory reaction, this system appears exquisitely controlled, making therapeutic manipula tion both possible and, to some extent, predictable.

Leucocyte Trafficking

Author : A. Hamann
Publisher : Springer Science & Business Media
ISBN 13 : 3662053977
Total Pages : 258 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Leucocyte Trafficking by : A. Hamann

Download or read book Leucocyte Trafficking written by A. Hamann and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

Textbook of Biochemistry with Clinical Correlations

Author : Thomas M. Devlin
Publisher : John Wiley & Sons
ISBN 13 : 0470281731
Total Pages : 1260 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Textbook of Biochemistry with Clinical Correlations by : Thomas M. Devlin

Download or read book Textbook of Biochemistry with Clinical Correlations written by Thomas M. Devlin and published by John Wiley & Sons. This book was released on 2010-01-19 with total page 1260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a clear and precise discussion of the biochemistry of eukaryotic cells, particularly those of mammalian tissues, relates biochemical events at a cellular level to the subsequent physiological processes in the whole animal, and cites examples of abnormal biochemical processes in human disease. The organization and content are tied together to provide students with the complete picture of biochemistry and how it relates to human diseases.

Neuroendocrine Immune Basis of the Rheumatic Diseases II

Author : Maurizio Cutolo
Publisher :
ISBN 13 :
Total Pages : 544 pages
Book Rating : 4.X/5 (4 download)

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Book Synopsis Neuroendocrine Immune Basis of the Rheumatic Diseases II by : Maurizio Cutolo

Download or read book Neuroendocrine Immune Basis of the Rheumatic Diseases II written by Maurizio Cutolo and published by . This book was released on 2002 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a September 21-23, 2001 conference. The papers in this volume examine the basic biochemical pathways from hormone metabolism to immune and inflammatory responses, as well as the effects of cytokines and glucocorticoid interactions in inflammatory diseases such as rheumatoid arthritis. Additional papers study the CNS and stress response involvement in autoimmune diseases including SLE (Systemic Lupus Erythematosus). Included are two overview articles that review the basic and clinical progress made over the past ten years in understanding and treating the rheumatic diseases.

The Cumulative Book Index

Author :
Publisher :
ISBN 13 :
Total Pages : 2362 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Cumulative Book Index by :

Download or read book The Cumulative Book Index written by and published by . This book was released on 1998 with total page 2362 pages. Available in PDF, EPUB and Kindle. Book excerpt: A world list of books in the English language.

Proceedings of the National Academy of Sciences of the United States of America

Author : National Academy of Sciences (U.S.)
Publisher :
ISBN 13 :
Total Pages : 1396 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Proceedings of the National Academy of Sciences of the United States of America by : National Academy of Sciences (U.S.)

Download or read book Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.) and published by . This book was released on 2001 with total page 1396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bibliography of Agriculture

Author :
Publisher :
ISBN 13 :
Total Pages : 1960 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Bibliography of Agriculture by :

Download or read book Bibliography of Agriculture written by and published by . This book was released on 1998 with total page 1960 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Book Publishing Record Cumulative 1998

Author : R R Bowker Publishing
Publisher :
ISBN 13 : 9780835240871
Total Pages : 1312 pages
Book Rating : 4.2/5 (48 download)

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Book Synopsis American Book Publishing Record Cumulative 1998 by : R R Bowker Publishing

Download or read book American Book Publishing Record Cumulative 1998 written by R R Bowker Publishing and published by . This book was released on 1999-03 with total page 1312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Forthcoming Books

Author : Rose Arny
Publisher :
ISBN 13 :
Total Pages : 1818 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Forthcoming Books by : Rose Arny

Download or read book Forthcoming Books written by Rose Arny and published by . This book was released on 1997 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt:

International Books in Print

Author :
Publisher :
ISBN 13 :
Total Pages : 1140 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis International Books in Print by :

Download or read book International Books in Print written by and published by . This book was released on 1998 with total page 1140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Books in Print

Author :
Publisher :
ISBN 13 :
Total Pages : 2432 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Books in Print by :

Download or read book Books in Print written by and published by . This book was released on 1991 with total page 2432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Impacts on Reproductive Health and Fertility

Author : Tracey J. Woodruff
Publisher : Cambridge University Press
ISBN 13 : 9780521519526
Total Pages : 262 pages
Book Rating : 4.5/5 (195 download)

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Book Synopsis Environmental Impacts on Reproductive Health and Fertility by : Tracey J. Woodruff

Download or read book Environmental Impacts on Reproductive Health and Fertility written by Tracey J. Woodruff and published by Cambridge University Press. This book was released on 2010-01-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Handbook of Oxidants and Antioxidants in Exercise

Author : C. Sen
Publisher : Elsevier
ISBN 13 : 0080538290
Total Pages : 1219 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of Oxidants and Antioxidants in Exercise by : C. Sen

Download or read book Handbook of Oxidants and Antioxidants in Exercise written by C. Sen and published by Elsevier. This book was released on 2000-02-16 with total page 1219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the science of exercise dates back to the time of ancient Greece. Today exercise is viewed not only as a leisurely activity but also as an effective preventive and therapeutic tool in medicine. Further biomedical studies in exercise physiology and biochemistry reports that strenuous physical exercise might cause oxidative lipid damage in various tissues. The generation of reactive oxygen species is elevated to a level that overwhelms the tissue antioxidant defense systems resulting in oxidative stress. The Handbook of Oxidants and Antioxidants in Exercise examines the different aspects of exercise-induced oxidative stress, its management, and how reactive oxygen may affect the functional capacity of various vital organs and tissues. It includes key related issues such as analytical methods, environmental factors, nutrition, aging, organ function and several pathophysiological processes. This timely publication will be of relevance to those in biomedical science and was designed to be readily understood by the general scientific audience.