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Nicotinic Receptors In The Central Nervous System
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Book Synopsis Nicotinic Receptors by : Robin A.J. Lester
Download or read book Nicotinic Receptors written by Robin A.J. Lester and published by Springer. This book was released on 2014-11-11 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets. It includes background information on all subtypes of nicotinic receptors, the most recent information on the distribution throughout the nervous system and discussion of their implications in learning and memory, addiction and neurological and psychiatric disease such as Alzheimer's and Parkinson's. Takes advantage of several recent developments in the fields of optogenetics, viral expression and gene analysis to focus on current knowledge on the functional aspects of nicotinic receptors.
Book Synopsis Nicotinic Acetylcholine Receptors in the Nervous System by : Francesco Clementi
Download or read book Nicotinic Acetylcholine Receptors in the Nervous System written by Francesco Clementi and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acetylcholine nicotinic receptor is an ionic channel whose aperture is directly controlled by acetylcholine. It is a key molecule in the chemical communication between nerve cells and between nerve cell and muscle. The structure and function of muscular nicotinic receptors have been unraveled in recent years and its beauty and mysteries were reviewed in the Santorini NATO ARW organized by Dr. Maelicke in 1986. The neat, linear structure of this molecule and its conservation throughout evolution, from bacteria to humans, have led to the suggestion that it has reached the optimal structure for performing its function. But when scientists began to look at the nicotinic receptor in the nervous system, they found several surprises. From the beginning, pharmacological and physiological experiments, have made it clear that the functional characteristics of neuronal nicotinic receptors are substantially different from those of muscle receptors. Furthermore, recent sophisticated techniques such as patch clamp and gene cloning have revealed that the nicotinic receptor in the nervous system is not a single molecule but (although there are some important exceptions) a large family of similar molecules, which have in common the property of binding nicotinic agonists or antagonists. Over the last few years, the physiological implications of nicotinic receptors have been reevaluated on the basis of more precise behavioural and pharmacological techniques. Moreover, the involvement of nicotinic receptors in degenerative pathologies of the eNS, such as Parkinson's and Alzheimer's disease, has also been discovered very recently.
Book Synopsis Nicotinic receptors in the central nervous system by : Christer Larsson
Download or read book Nicotinic receptors in the central nervous system written by Christer Larsson and published by . This book was released on 1985 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nicotinic Receptors in the CNS written by and published by . This book was released on 1989 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nicotinic Receptors in the Nervous System by : Edward D. Levin
Download or read book Nicotinic Receptors in the Nervous System written by Edward D. Levin and published by CRC Press. This book was released on 2001-08-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of research on neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. By bringing together molecular and neurochemical applications, the book provides the key to understanding function and dysfunction of nicotinic systems and how they are significant for disease, addiction, and the development of novel drug treatments. The book presents readers with the basic mechanistic background for these treatments as well as the functional assessment necessary to determine therapeutic effects.
Book Synopsis Cellular and Molecular Neurophysiology by : Constance Hammond
Download or read book Cellular and Molecular Neurophysiology written by Constance Hammond and published by Elsevier. This book was released on 2024-06-03 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Neurophysiology, Fifth Edition is the only up-to-date textbook on the market that focuses on the molecular and cellular physiology of neurons and synapses. Hypothesis-driven rather than a dry presentation of the facts, the book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in graduate-level courses on the topic alike. This new edition explains the molecular properties and functions of excitable cells in detail and teaches students how to construct and conduct intelligent research experiments. The content is firmly based on numerous experiments performed by top experts in the field. The new edition contains new chapters on recording neuronal activity, iconotrophic and metabotropic receptors for sensory transduction, and a section containing exercises for further learning. This book will be a useful resource for neurophysiologists, neurobiologists, neurologists, and students taking graduate-level courses on neurophysiology. Authoritative foundational coverage of basic cellular and molecular neurophysiology Includes new chapters on recording neuronal activity, iconotrophic and metabotropic receptors for sensory transduction Provides fifteen appendices that describe how neurobiological techniques are interspersed in the text Presents enhanced coverage of new methodologies and experimental techniques
Book Synopsis Insect Nicotinic Acetylcholine Receptors by : Steeve Hervé Thany
Download or read book Insect Nicotinic Acetylcholine Receptors written by Steeve Hervé Thany and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out some of the future challenges. For example, we need to determine the precise subunit nomenclature of insect nicotinic receptors. This nomenclature varies amongst species and this led to some of the early confusion that persists. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.
Download or read book Nicotinic Receptors in the CNS written by and published by . This book was released on 1989 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Encyclopedia of Clinical Neuropsychology by : Jeffrey Kreutzer
Download or read book Encyclopedia of Clinical Neuropsychology written by Jeffrey Kreutzer and published by Springer Science & Business Media. This book was released on 2010-09-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Encyclopedia goes beyond other references in the field to offer concise and comprehensive coverage of assessment, treatment and rehabilitation in a single source, with more than fifteen hundred entries with linked cross-references and suggested readings.
Book Synopsis Adenosine Receptors in Health and Disease by : Constance N. Wilson
Download or read book Adenosine Receptors in Health and Disease written by Constance N. Wilson and published by Springer Science & Business Media. This book was released on 2009-07-28 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.
Book Synopsis Neuroscience of Nicotine by : Victor R. Preedy
Download or read book Neuroscience of Nicotine written by Victor R. Preedy and published by Academic Press. This book was released on 2019-03-20 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects
Book Synopsis CNS Neurotransmitters and Neuromodulators by : Trevor W. Stone
Download or read book CNS Neurotransmitters and Neuromodulators written by Trevor W. Stone and published by CRC Press. This book was released on 2020-10-28 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series CNS Neurotransmitters and Neuromodulators is destined to be the definitive reference work on the physiology and pharmacology of the central nervous system. Written by an outstanding group of international authors, chapters cover a wide range of interdisciplinary aspects of the subject. This first volume includes an in-depth examination of acetylcholine, ranging from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. This indispensable and comprehensive reference keeps you abreast of new developments in several areas of neuroscience.
Book Synopsis Neuronal Nicotinic Receptors by : F. Clementi
Download or read book Neuronal Nicotinic Receptors written by F. Clementi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 837 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal nicotinic receptors are key molecules for signal transduction in a number of neuronal pathways. They are widely distributed in the brain and are known to be involved in cognitive tasks, including learning and memory, in smoking addiction and in several brain diseases, such as Alzheimer's and Parkinson's dementias, schizophrenia, and epilepsy. This book provides a comprehensive review of the field, starting with a historical perspective and dealing with the molecular structure of these receptors, their biophysical and pharmacological properties, their distribution in central and peripheral nervous systems, and their major involvement in brain functions. Particular emphasis is paid to drugs (both new and old) that are useful in the diagnosis and treatment of diseases involving neuronal nicotinic receptors. Finally, the relevance of these receptors in smoking addiction is carefully evaluated, together with future trends and the latest results.
Book Synopsis Understanding Drug Action by : Peter J. Rice
Download or read book Understanding Drug Action written by Peter J. Rice and published by Amer Pharmacists Assn. This book was released on 2013-11-11 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Drug Action: An Introduction to Pharmacology provides readers with a survey of the scientific understanding of drug action. This readable introduction to pharmacology is simple enough to be understood without having to take a class to follow the material, but can also be used to complement a course in pharmacology. The approach to pharmacology is at a basic scientific level to build a framework of how drugs work supplemented with information on some representative drugs that are used clinically. Each chapter includes review questions and many chapters include tables of important drugs with brand and generic names.
Book Synopsis Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic by : Jordan Grafman
Download or read book Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic written by Jordan Grafman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last twenty years there has been an explosive growth in our understanding of the molecular, cellular, and anatomical changes that occur in the days and weeks following brain injury. It is now clear that training and exposure to certain environments can modify and shape neuronal plasticity in lower animals and humans. In humans, in particular, there are new ways of charting neuronal plasticity at the ensemble or regional level using functional neuroimaging techniques such as positron emission tomography and functional magnetic resonance imaging. Thus, the time seems right for transporting the laboratory results to the clinic so that experimental findings can be tested in the "field". This volume provides some impetus to moving the field of cognitive neuroscience a little further in its efforts to improve the lives of patients who have suffered a debilitating brain injury.
Book Synopsis Autonomic Failure by : Roger Bannister
Download or read book Autonomic Failure written by Roger Bannister and published by Oxford University Press, USA. This book was released on 1983 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life is a journey and we all have to go thru this progress. When I make wrong choices it was for a reason, it was for a purpose. I had to learn from it.I can not be ashamed of No one.I can not think that I am better then No One Else.I can not think less of No one Else.I can not talk about No One.Because My Father was not ashamed of Me.Because My Father did not think less of Me.Because My Father did not talk about my dirt or my sins to Anyone.Because My Father did not think that he was Better then me.HE ONLY LOVE ME
Book Synopsis Autonomic Neurology by : Eduardo E. Benarroch
Download or read book Autonomic Neurology written by Eduardo E. Benarroch and published by Oxford University Press. This book was released on 2014-04-03 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. The first section includes 5 chapters reviewing the anatomical and biochemical mechanisms of central and peripheral nervous system control of autonomic function, principles of autonomic pharmacology, and a clinical and laboratory approach to the diagnosis of autonomic disorders. The second section focuses on the pathophysiology and management of orthostatic hypotension, postural tachycardia, baroreflex failure; syncope, disorders of sweating, neurogenic bladder and sexual dysfunction, gastrointestinal dysmotility, and autonomic hyperactivity. The final section is devoted to specific autonomic disorders, including central neurodegenerative disorders; common peripheral neuropathies with prominent autonomic failure; painful small fiber neuropathies; autoimmune autonomic ganglionopathies and neuropathies; focal brain disorders; focal spinal cord disorders; and chronic pain disorders with autonomic manifestations. This book is the product of the extensive experience of its contributors in the evaluation and management of the many patients with autonomic symptoms who are referred for neurologic consultation at Mayo Clinic in Rochester, Minnesota. Autonomic Neurology focuses on clinical scenarios and presentation of clinical cases and includes several figures showing the results of normal and abnormal autonomic testing in typical conditions. Its abundance of tables summarizing the differential diagnosis, testing, and management of autonomic disorders also help set this book apart from other books focused on the autonomic nervous system.
