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Author : W. Gerok
Publisher : Springer
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)
Download or read book New Trends in Hepatology 1996 written by W. Gerok and published by Springer. This book was released on 1997-03-31 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the Falk Symposium No. 92, St. Petersburg
Author : P. Gentilini
Publisher : Springer Science & Business Media
ISBN 13 : 940090357X
Total Pages : 352 pages
Book Rating : 4.4/5 (9 download)
Download or read book New Trends in Hepatology written by P. Gentilini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Italian Group for the Study of Liver Cirrhosis began its activity in 1980 on the basis of recognition and financial support from the Italian Ministry of the University, Scientific Research and Technology, having been chosen from several other scientific programs. The group is now called the National Group for the Study of Liver Cirrhosis and Viral Hepatitis and includes more than 40 centers throughout the nation under the auspices of the universities. The primary Imtlatlve of the group, to combine experimental and clinical approaches in the study of liver pathophysiology, remains unchanged. Annual meetings in January provide the possibility of comparing experimental and clinical results in the spirit of mutual comprehension and criticism. After 15 years and 6 volumes (published biannually), the actual improvement of Italian research in liver pathophysiology is evident. In fact, in order to let other researchers know what has been achieved we chose to publish the 7th volume, in spite of the economic difficulties at hand. We have gathered specific experiences of all the centers included in the national program. Each group was required to present an update in its own field of research, rather than specific or recently obtained results, which could have been reported only in relationship with other data already published by others. Like the 6th edition in our series, this volume affirms the specific competence of all the participants and summarizes the most important updates in liver pathophysiology.
Author : S.K. Lam
Publisher : Springer
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)
Download or read book Update on Hepatobiliary Diseases 1996 written by S.K. Lam and published by Springer. This book was released on 1996 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium 90 held in Hong Kong, February 29-March 1, 1996, presents the most recent advances in all major fields of hepatology. World experts discuss basic and clinical aspects of viral hepatitis, toxic, metabolic and cholestatic liver diseases, liver cirrhosis, hepatocellular carcinoma, gallstone disease and liver transplantation. In the two sections devoted to viral hepatitis, special attention is given to hepatitis C. Besides interferon, new antiviral therapies are discussed. In the section on toxic and metabolic liver diseases, besides drug-induced liver injuries and inborn errors of metabolism, alcoholic liver disease is of special interest. New interventional treatments for portal hypertension and ascites are discussed in the section on cirrhosis. In the section on hepatocellular carcinoma different therapeutic strategies are compared. An update on pathogenesis and treatment of gallstone disease is also included. The book concludes with a section addressing the newest trends in liver transplantation. Thus, this book presents the most complete update on hepatobiliary diseases in Asia in 1996.
Author : J.F. Riemann
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387619
Total Pages : 184 pages
Book Rating : 4.3/5 (876 download)
Download or read book Interventional Endoscopy in Hepatology written by J.F. Riemann and published by Springer Science & Business Media. This book was released on 2000-08-31 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of Falk Symposium No. 116, held in Basel, Switzerland, October 25, 1999, (Part III of the Basel Liver Week 1999)
Author : F. Hagenmüller
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387749
Total Pages : 262 pages
Book Rating : 4.3/5 (877 download)
Download or read book Medical Imaging in Gastroenterology and Hepatology written by F. Hagenmüller and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium 124, `Medical Imaging in Gastroenterology and Hepatology' (Progress in Gastroenterology and Hepatology Part I), held in Hannover, Germany, on September 28-29, 2001, aims to demonstrate the newest developments in the various imaging techniques for diagnosis and therapy, coupled with overviews by renowned international experts. In this book, up-to-date technologies in medical imaging and image documentation as well as the most modern transmission techniques should bridge the gap between futuristic research and everyday clinical practice.
Author : H.E. Blum
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387954
Total Pages : 266 pages
Book Rating : 4.3/5 (879 download)
Download or read book State of the Art of Hepatology written by H.E. Blum and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In honour of Hans Popper's 100th birthday
Author : G. Holtmann
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387831
Total Pages : 316 pages
Book Rating : 4.3/5 (878 download)
Download or read book Gastrointestinal Inflammation and Disturbed Gut Function: The Challenge of New Concepts written by G. Holtmann and published by Springer Science & Business Media. This book was released on 2003-09-30 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium 130 on 'Gastrointestinal Inflammation and Disturbed Gut Function: The Challenge of New Concepts', held in Freiburg, Germany, on October 4-6, 2002 (Part I of the Gastroenterology Week Freiburg 2002), reviews ground-breaking work and will stimulate new research in the functional GI disorders, from the bench to the bedside. Basic scientists, clinical researchers and clinicians interested in this field explore controversial and exciting areas of research, and consider targets for future therapeutic interventions.
Author : M.P. Manns
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387596
Total Pages : 426 pages
Book Rating : 4.3/5 (875 download)
Download or read book Immunology and Liver written by M.P. Manns and published by Springer Science & Business Media. This book was released on 2000-08-31 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992, the Falk Symposium No. 70 dealt with the topic `Immunology and Liver'. At that time basic mechanisms of immunology as well as immunopathogenetic mechanisms in viral and autoimmune liver diseases were discussed. Now, 7 years later, the Falk Symposium No. 114, held in Basel, Switzerland, October 20-21 1999 (Part I of the Basel Liver Week 1999), focused on immunology in autoimmune liver diseases. In the first section basic mechanisms of autoimmunity are presented, including the relevance of superantigens and the role of apoptosis. A further topic is the latest developments concerning animal models for autoimmune diseases. Recently the International Autoimmune Hepatitis Group newly defined and reclassified the syndrome of autoimmune hepatitis. Autoimmune hepatitis is now identified and studied in all parts of the world, including Asia and South America. A special variant of autoimmune hepatitis was identified as one organ manifestation of the autoimmune polyendocrine syndrome type 1, a genetic disease caused by mutations in a single transcription factor. Drug- and hepatitis-virus induced immune mediated liver diseases may serve as models for nonhepatic immune mediated disorders. DNA technology has increased our knowledge of the immunogenetic background of autoimmune liver diseases. Among the cholestatic immune mediated liver diseases, significant progress has been made concerning primary biliary cirrhosis, in particular regarding the identification of mitochondrial antigens and the characterisation of the immune reactions directed at them. The involvement of infectious agents in PBC as well as the definition of overlap syndromes is a particular focus for basic and clinical research in this area. Concerning the therapy of autoimmune liver diseases, corticosteroids and azathioprin remain the state of the art for autoimmune hepatitis, while bile acids have become well established in treatment of primary biliary cirrhosis as well as primary sclerosing cholangitis. New drugs in the future will include topical steroids such as budesonide and new immunosuppressive agents like mofetil/mycophenolate. Liver transplantation is the treatment of choice for end stage liver diseases; all autoimmune liver diseases are among the best candidates for liver transplantation. Hopefully, new therapeutic strategies based on the results obtained from experimental models will become everyday clinical practice in the next decade. Therefore this symposium concludes with a discussion.
Author : H.E. Blum
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387367
Total Pages : 450 pages
Book Rating : 4.3/5 (873 download)
Download or read book Gut and the Liver written by H.E. Blum and published by Springer Science & Business Media. This book was released on 1998-02-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium 100, `Gut and the Liver', held in Freiburg, Germany, 29-31 May 1997, comprehensively reviews the physiological and pathophysiological interactions between the intestine and the liver as well as between intestinal and hepatic diseases. Apart from the basic aspects of the intestinal microflora and the immune system of the gut, gastrointestinal permeability and translocation as well as the contribution of the intestine and the intestinal bacteria to the metabolism of bile acids, amino acids and drugs are discussed. In addition, experimental as well as clinical data demonstrating the significance of gut-derived bacterial toxins for the development of liver diseases and the effect of liver diseases on gastrointestinal functions are discussed. The major aim of this book, therefore, is to highlight the interactions between gut and liver at the molecular level as well as in clinical disease.
Author : M. Lukás
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387923
Total Pages : 338 pages
Book Rating : 4.3/5 (879 download)
Download or read book Immunological Diseases of Liver and Gut written by M. Lukás and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 135 held in Prague, Czech Republic, on September 12-13, 2003, and is dedicated to the important issue of immunological aspects of diseases of the liver and gut. Without any doubt, immunological pathways are among the most important and universal factors in the pathogenesis of all diseases. Their importance is also constantly increasing, because these principles have been adopted in clinical practice for both diagnostic and therapeutic procedures. Chapters by prominent experts will stimulate new ideas and set the scene for productive discussion on this topic.
Author : U. Leuschner
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387930
Total Pages : 424 pages
Book Rating : 4.3/5 (879 download)
Download or read book Cholestatic Liver Diseases: Therapeutic Options and Perspectives written by U. Leuschner and published by Springer Science & Business Media. This book was released on 2004-06-30 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last decade, knowledge about cholestatic liver disease and concomitant diseases, such as ulcerative colitis, cholangio- and hepatocellular carcinoma, pancreas and colon cancer, has increased considerably. Studies on ursodeoxycholic acid treatment alone or in combination with immunosuppressive compounds and their positive effects on biliary liver disease as well as on so-called overlap syndromes or intestinal tumors are published in increasing numbers, and stimulate discussion on whether or not ursodeoxycholic acid is able to improve the general condition and/or life expectancy of patients. On the other hand, genetics, aetiological and pathogenetic aspects are still difficult to comprehend, but are the absolute prerequisite for the development of better treatment options. This book is the proceedings of Falk Symposium No. 136 (Part I of the XII Falk Liver Week, held in Freiburg, Germany, on October 15-16, 2003), and contains stimulating, exciting and controversial papers on clinical and also basic research at the highest scientific level.
Author : N. Hiyashi
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387961
Total Pages : 140 pages
Book Rating : 4.3/5 (879 download)
Download or read book Prevention of Progression in Chronic Liver Disease written by N. Hiyashi and published by Springer Science & Business Media. This book was released on 2004-07-21 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: In several liver diseases, the underlying cause cannot always be eliminated, i.e. the progression of liver disease cannot be prevented. This is particularly true for non-responders to the treatment of chronic hepatitis C (HCV). It is relevant for more than 40% of patients with HCV genotype 1 and up to 20% of patients with genotype 2 or 3. Several approaches are now underway to prevent or ameliorate mechanisms of disease progression. In Asia, and particularly in Japan, Glycyrrhizine-SNMC has been widely used for this purpose. At present, SNMC is under clinical evaluation in Europe. This book, the proceedings of the Falk Workshop on 'Prevention of Progression in Chronic Liver Disease - An Update on SNMC (Stronger Neo-Minophagen C)' (Part IV of the XII Falk Liver Week, in honour of Hans Popper's 100th birthday) held in Freiburg, Germany, on 22 October 2003, is devoted to the understanding of basic mechanisms of fibrogenesis, the state of the art of non-invasive markers of disease progression that may substitute liver biopsy in the future, and of other predictive parameters indicating disease progression, in particular the development of hepatocellular carcinoma. All these problems are particularly relevant for chronic hepatitis C. A better characterization of so-called non-responders for the treatments available is crucial for the development of new strategies preventing or postponing disease progression. Such strategies should influence fibrogenesis and, thus, cirrhosis formation as well as the development of life threatening complications of liver cirrhosis, including hepatocellular carcinoma. In this volume, the available information on SNMC as an approach to prevent progression of chronic liver disease is discussed by several internationally renowned authors who report on the mechanisms of liver fibrogenesis and fibrolysis, on non-invasive markers of disease progression, and on hepatocellular carcinoma as one of the major complications of liver cirrhosis nowadays. Finally, experts from Japan report on their knowledge and experience concerning the drug SNMC/Glycyrrhizine in the prevention of cirrhosis and HCC, and first study results from Europe are presented.
Author : F. Berr
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387794
Total Pages : 242 pages
Book Rating : 4.3/5 (877 download)
Download or read book Malignant Liver Tumours: Basic Concepts and Clinical Management written by F. Berr and published by Springer Science & Business Media. This book was released on 2002-11-30 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), both increasing in incidence, have become a major topic of basic and clinical research as well as clinical practice in hepatology. Experts in the field update the current concepts on the carcinogenesis of HCC and CC such as genetic alterations in the pathways of cell cylce and apoptosis regulation, the hypothesis of dedifferentiation of hepatocytes to the malignant phenotype vs that of activation of hepatic progenitor cells incapable of maturation (maturation arrest hypothesis). In spite of an increasing number of genetic alterations described in human HCC as well as cell regulatory pathways tested in experimental HCC models, the key hits causing progression of the cell cycle in imbalance with apoptosis, tissue invasive growth and metastatic potential of cell clones still remain elusive. Very powerful genomic and proteomic techniques are promising insights into the carcinogenesis of liver malignancies that will allow more efficient therapeutic strategies. The current concepts on risk profiling, surveillance of risk groups and therapeutic strategies are evidence-based for HCC and less detailed for CC. Surveillance of risk groups improves detection of liver tumours in curable stages. Best strategies for curative treatment of HCC use neoadjuvant antitumour therapies before liver transplantation and a role is emerging for living donor-related liver transplantation. New palliative therapies for HCC are in the experimental stage with biological response modifiers, including angiogenesis inhibitors, and entering phase II clinical trials with the alpha-fetoprotein derived vaccines.
Author : K. Fellermann
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387671
Total Pages : 288 pages
Book Rating : 4.3/5 (876 download)
Download or read book Immunosuppression in Inflammatory Bowel Diseases written by K. Fellermann and published by Springer Science & Business Media. This book was released on 2001-06-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aetiology of the chronic inflammatory bowel diseases - Crohn's disease and ulcerative colitis - is still enigmatic. The therapeutic approach has therefore traditionally focused on anti-inflammatory principles, including corticosteroids and aminosalicylates. Since a significant proportion of patients is steroid-dependent or refractory and because of the problematic side-effects of long-term systemic steroids, active immunosuppression has gained acceptance in the field. The classical immunosuppressants azathioprine and 6-mercaptopurine have long been evidence-based in IBD, but underused. Recently, methotrexate and cyclosporine have also been proven to be effective in certain situations. Newer drugs like tacrolimus, mycophenolate and others may be similarly useful but their potential is still unclear. Finally, the immune modifiers including IL-10 and TNF-antibodies have been successfully subjected to controlled trials. Other experimental drugs discussed in this book are on the horizon. This volume is the Proceedings of Falk Symposium 119 held in Freiburg-im-Breisgau, Germany, October 3-4, 2000, and covers systematically the field of immunosuppression in inflammatory bowel diseases. It is hoped that it will further the prudent use of these drugs in the proper clinical situations by increasing our understanding of both the mechanisms of action and the clinical benefit to the patient.
Author : Faruk Hadziselimovic
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387787
Total Pages : 304 pages
Book Rating : 4.3/5 (877 download)
Download or read book Autoimmune Diseases in Pediatric Gastroenterology written by Faruk Hadziselimovic and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the proceedings of the Falk Symposium No. 127 on `Autoimmune Diseases in Paediatric Gastroenterology' (IV International Falk Symposium on Paediatric Gastroenterology), held in Basel, Switzerland, on November 8-9, 2001. The symposium focused on the role of the immune system, both the acquired and the innate systems, in inflammatory bowel disease (IBD) in children and adolescents. The innate system has an important fundamental role in host defence by initiating immune responses against potentially deleterious matter. However, a mutation within the innate system may elicit an immune response against the host: hence, an autoimmune response. Chronic autoimmune hepatitis occurs predominantly in young people, and especially in women. Immunological changes are conspicuous. Tissue antibodies are found in a large number of patients. This is a disease of disordered immunoregulation marked by a deficit in suppressor T cells causing the production of autoantibodies against specific hepatocyte surface antigen. Liver membrane protein is found in the sera of patients with autoimmune chronic acute hepatitis and with primary biliary cirrhosis (PBC). The latter condition of progressive granulomatous destruction of intrahepatic bile ducts is, in many respects, analogous to the graft-versus-host syndrome where the immune system has become sensitized to foreign HLA-molecules. Primary sclerosing cholangitis (PSC) is another condition of unknown origin. All parts of the biliary tree can be involved in a chronic, fibrosing, inflammatory process that results in obliteration of the biliary tree and ultimately in biliary cirrhosis. About half of the patients also suffer from ulcerative colitis and rarely from Crohn's disease. Circulating antibodies to some antigens are found in obstructed portal tracts, as well as increased concentrations of biliary immune complexes in patients with PBC. In all three previous Falk symposia on paediatric gastroenterology, attention was focused on the role of the innate immune system in the aetiology of IBD. It has become increasingly clear in recent years that the innate system has a much more important and fundamental role in host defence. The decision to initiate an immune response is one of the major roles of the innate system. Mutations within this system could transform it into becoming constitutively active, resulting in an inflammatory reaction and thus eliciting an autoimmune response. Following an introduction to the basic phenomena of autoimmunity, the proceedings discuss clinical aspects of autoimmune diseases. In particular, current knowledge and the state of the art about the diagnosis and treatment of the autoimmune diseases of the gastrointestinal tract are described by world-renowned experts. The book also contains the short presentations on selected topics, as well as abstracts of the mini-posters read by title, which were included in the symposium.
Author : A. Stallmach
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387473
Total Pages : 350 pages
Book Rating : 4.3/5 (874 download)
Download or read book Induction and Modulation of Gastrointestinal Inflammation written by A. Stallmach and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the proceedings of Falk Symposium No. 104, organized in collaboration with the Society of Mucosal Immunology, and held in Saarbrucken, Germany, March 5-7 1998, is centered around the immunological mechanisms of mucosal protection and their disturbances leading to intestinal inflammation and destruction. This is a rapidly expanding field involving recent knowledge of basic immunology and cell biology as well as clinical observations. The conference and this book summarize very recent data in this field and suggest strategies for future research and clinical applications, and will be of interest to both basic scientists and clinicians.
Author : P.R. Galle
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387855
Total Pages : 282 pages
Book Rating : 4.3/5 (878 download)
Download or read book Disease Progression and Carcinogenesis in the Gastrointestinal Tract written by P.R. Galle and published by Springer Science & Business Media. This book was released on 2003-09-30 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development and progression of gastrointestinal disease involves inflammatory, vascular, fibrogenetic and immune reactions accompanied by deregulation of cellular growth and death often resulting in cancer of the organs affected. This book, the proceedings of Falk Symposium 132 on `Disease Progression and Carcinogenesis in the Gastrointestinal Tract', held in Freiburg, Germany, October 9-10, 2002, addresses these various cellular processes in five sections in order to build up a broad pathogenic concept of gastrointestinal disease, purposely going beyond organ-specific research. Each section combines experts in the various fields of molecular medicine together with clinical scientists in order to stimulate interdisciplinary discussion. In addition, clinical chapters focus on new findings in both diagnostics and therapeutics.
