New Treatment Strategies for Dengue and Other Flaviviral Diseases

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470058013
Total Pages : 276 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis New Treatment Strategies for Dengue and Other Flaviviral Diseases by : Gregory R. Bock

Download or read book New Treatment Strategies for Dengue and Other Flaviviral Diseases written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2006-10-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are four serotypes of dengue virus, of which DENV-2 has been the most prevalent in many recent epidemics. Following primary infection, lifelong immunity develops, preventing repeated assault by the same serotype. However, the non-neutralizing antibodies from a previous infection or maternally acquired antibodies are thought to form complexes with a different serotype during a subsequent infection and cause dengue haemorrhagic fever/dengue shock syndrome, which can be fatal. There is no treatment or vaccine available today that can combat this emerging and uncontrolled disease. This book features contributions from the world’s leading researchers working on dengue and related flaviviruses who examine the current state of the art in the molecular biology of the dengue virus. Particular emphasis is placed on the structure and function of the virus and the targeting of virus proteins by potential antiviral agents. The pathogenesis of dengue and dengue haemorrhagic fever are discussed in detail, especially the target cells and the specific receptors on these cells, thereby developing a clear overview of host and viral factors that contribute to dengue haemorrhagic fever. Finally, the book reviews the therapeutic options, paying particular attention to ways in which vector, host and environment can play a critical role in the spread of this disease. With dengue fever and other emerging viral diseases becoming increasingly prevalent around the world, this book provides valuable insight into the virus that causes this disease and potential ways to manage it. It is essential reading for all those working in tropical diseases, public health and virology. Praise from the reviews: "The book provides an excellent summary of dengue/flavivirus research and is important for individuals and institutions interested in emerging infectious diseases." MICROBIOLOGY TODAY

Dengue and Zika: Control and Antiviral Treatment Strategies

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Author :
Publisher : Springer
ISBN 13 : 981108727X
Total Pages : 375 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Dengue and Zika: Control and Antiviral Treatment Strategies by : Rolf Hilgenfeld

Download or read book Dengue and Zika: Control and Antiviral Treatment Strategies written by Rolf Hilgenfeld and published by Springer. This book was released on 2018-05-29 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume contains 25 chapters from leading international scientists working on dengue and Zika viruses, who came together in Praia do Tofo in Mozambique to discuss the latest developments in the fields of epidemiology, pathogenesis, structural virology, immunology, antiviral drug discovery and development, vaccine efficacy, and mosquito control programs. The meeting venue offered an opportunity to discuss current research on these flaviviruses in an idyllic setting, and also to develop first-hand appreciation of the issues in infectious diseases facing developing countries and of the research gaps in Africa. For readers, who should include basic and clinical researchers in the field and public health professionals, the chapters are organized to provide a comprehensive overview of the various topics in current dengue and Zika virus research. A unique feature of the proceedings of this meeting is the inclusion of the discussions that took place following presentations. These have been transcribed and appended to the end of the relevant chapters, and they form the “salt in the soup” of this book.

Dengue

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Publisher : World Health Organization
ISBN 13 : 9241547871
Total Pages : 159 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Dengue by : World Health Organization

Download or read book Dengue written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.

CDC Yellow Book 2018: Health Information for International Travel

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Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 672 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Dengue Virus Disease

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Publisher : Academic Press
ISBN 13 : 0128182717
Total Pages : 202 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Dengue Virus Disease by : Adnan I. Qureshi

Download or read book Dengue Virus Disease written by Adnan I. Qureshi and published by Academic Press. This book was released on 2019-11-23 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. This estimate puts nearly half the world’s population at risk. This book reviews the history, clinical and diagnostic aspects of dengue virus, also presenting our current knowledge on the pathophysiology of severe dengue and addressing the importance of dengue virus infections in those traveling to parts of the world where it is endemic. Covers every important aspect of Dengue virus disease, from biological, to its social and economic impacts Highlights the unique aspects of Dengue virus infection and the evolving nature of our understanding of the virus Provides a complete description of Dengue virus disease, with details on more recent outbreaks, clinical features, first hand experiences, treatment modalities, and recent novel treatment regimens Gives insights into the detailed psychological impact the disease has caused in outbreak regions

West Nile Encephalitis Virus Infection

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Publisher : Springer Science & Business Media
ISBN 13 : 0387798404
Total Pages : 489 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis West Nile Encephalitis Virus Infection by : Michael S. Diamond

Download or read book West Nile Encephalitis Virus Infection written by Michael S. Diamond and published by Springer Science & Business Media. This book was released on 2009-02-12 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: West Nile virus is a neurotropic flavivirus that has emerged globally as a primary cause of viral encephalitis. Infection of humans and other vertebrate animals is associated with a febrile illness that can progress to a lethal encephalitis or flaccid paralysis syndrome. Its appearance in the Western Hemisphere in 1999 and the corresponding increase in global disease burden over the last decade have been accompanied by intensive study, including the entry of many scientists into the field. Breakthroughs have been made in understanding the unique transmission pattern between the vector and the multiple avian and mammalian hosts and targets. Studies in mammalian systems have dissected the viral and host factors that determine the pathogenesis and outcome of West Nile virus infection. On the basis of these experiments, progress has been made on the identification of genetic factors that predispose to severe human disease. Thus, in a remarkably short period of time, insight has been gained on a wide variety of disciplines related to West Nile virus biology. The aim of this book was to assemble an up-to-date and cutti- edge anthology from the leading experts in the field. The chapters are balanced by submissions from newcomers who have made significant recent contributions with those from established investigators who have dedicated their careers to the study of West Nile virus.

New Drug Development for Known and Emerging Viruses

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Publisher : John Wiley & Sons
ISBN 13 : 3527343377
Total Pages : 530 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis New Drug Development for Known and Emerging Viruses by : Helga Rübsamen-Schaeff

Download or read book New Drug Development for Known and Emerging Viruses written by Helga Rübsamen-Schaeff and published by John Wiley & Sons. This book was released on 2022-01-31 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the pharmaceutical industry and public health agencies.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

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Author :
Publisher : World Health Organization
ISBN 13 : 9241564865
Total Pages : 211 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Investing to Overcome the Global Impact of Neglected Tropical Diseases by : World Health Organization

Download or read book Investing to Overcome the Global Impact of Neglected Tropical Diseases written by World Health Organization and published by World Health Organization. This book was released on 2015-08-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Dengue and Dengue Hemorrhagic Fever in the Americas

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Author :
Publisher : Pan American Health Organization
ISBN 13 :
Total Pages : 112 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis Dengue and Dengue Hemorrhagic Fever in the Americas by : Pan American Sanitary Bureau

Download or read book Dengue and Dengue Hemorrhagic Fever in the Americas written by Pan American Sanitary Bureau and published by Pan American Health Organization. This book was released on 1994 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dengue and its potentially fatal forms, dengue henorrhagic fever and dengue shock syndrome, once more threaten much of the Americas. In the 1980s the vector control programmes fell victim to the cutbacks in public health expenditure and their responses to dengue outbreaks tended to be a little too late. These guidelines have risen to the challenge by incorporating all aspects of the prevention and control of the disease and its vectors. In addition, because dengue is primarily a problem of domestic sanitation and households can combat the problem inexpensively. The guidelines enmphasize ways to transfer responsibility for dengue control and prevention to the community."

Dengue and Dengue Hemorrhagic Fever, 2nd Edition

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Author :
Publisher : CABI
ISBN 13 : 1845939646
Total Pages : 624 pages
Book Rating : 4.8/5 (459 download)

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Book Synopsis Dengue and Dengue Hemorrhagic Fever, 2nd Edition by : Duane J. Gubler

Download or read book Dengue and Dengue Hemorrhagic Fever, 2nd Edition written by Duane J. Gubler and published by CABI. This book was released on 2014-08-29 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continued geographic expansion of dengue viruses and their mosquito vectors has seen the magnitude and frequency of epidemic dengue/dengue hemorrhagic fever (DF/DHF) increase dramatically. Recent exciting research on dengue has resulted in major advances in our understanding of all aspects of the biology of these viruses, and this updated second edition brings together leading research and clinical scientists to review dengue virus biology, epidemiology, entomology, therapeutics, vaccinology and clinical management.

Dengue Fever

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Publisher : BoD – Books on Demand
ISBN 13 : 1789849993
Total Pages : 182 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Dengue Fever by : Jorge Abelardo Falcón-Lezama

Download or read book Dengue Fever written by Jorge Abelardo Falcón-Lezama and published by BoD – Books on Demand. This book was released on 2019-01-30 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 70 years, dengue fever has challenged health systems in every region of the World. It has evolved from a benign febrile illness from the tropics to a major concern in urban settlements, overwhelming health infrastructure with large outbreaks, as it continues to teach us important lessons with its complexities. This book intends to review the latest updates on dengue fever, the tools available for its study and control, and promising technologies currently in the pipeline. With this work, the editors wish to provide students with an updated reference text on the basics of this disease as well as researchers and academics, with a useful document to understand the current outlook and the perspectives for the future.

Global Health Impacts of Vector-Borne Diseases

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Author :
Publisher : National Academies Press
ISBN 13 : 0309377595
Total Pages : 397 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Global Health Impacts of Vector-Borne Diseases by : National Academies of Sciences, Engineering, and Medicine

Download or read book Global Health Impacts of Vector-Borne Diseases written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-10-21 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Viral Infections and Antiviral Therapies

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Publisher : Academic Press
ISBN 13 : 032397242X
Total Pages : 810 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Viral Infections and Antiviral Therapies by : Amal Kumar Dhara

Download or read book Viral Infections and Antiviral Therapies written by Amal Kumar Dhara and published by Academic Press. This book was released on 2022-11-10 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral Infections and Antiviral Therapies provides comprehensive coverage of viral infections and their transmission. Coverage includes antiviral agents, therapeutics, their mechanisms and treatment strategies. The book is organized into four sections, including an introduction to antiviral therapies, viral infections and their transmission, antiviral agents and therapeutics, and a market overview and future developments. The chapters in each section of the book discuss various key topics that are contributed to by an international group of leading experts. Covers emerging and sexually transmitted viruses, including mode of transmission and pathophysiology of viral infections Describes antiviral agents and therapeutics for viruses such as rotaviruses, enteroviruses and coronaviruses Discusses strategies for the delivery of antiviral agents and vaccinations

Neglected Tropical Diseases - Middle East and North Africa

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Publisher : Springer
ISBN 13 : 3709116139
Total Pages : 282 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Neglected Tropical Diseases - Middle East and North Africa by : Mary Ann McDowell

Download or read book Neglected Tropical Diseases - Middle East and North Africa written by Mary Ann McDowell and published by Springer. This book was released on 2014-07-17 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Middle East and North Africa (MENA) is highly endemic for several neglected tropical diseases (NTDs), including viral, bacterial, protozoan and helminth infections. This new volume covers the most prevalent NTDs found in about 22 MENA countries emphasizing the disease burden, clinical manifestations and control approaches. Each individual chapter deals with one specific disease and is written by a group of experts on that topic.

Emerging pests and vector-borne diseases in Europe

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Author :
Publisher : BRILL
ISBN 13 : 9086866263
Total Pages : 499 pages
Book Rating : 4.0/5 (868 download)

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Book Synopsis Emerging pests and vector-borne diseases in Europe by : Willem Takken

Download or read book Emerging pests and vector-borne diseases in Europe written by Willem Takken and published by BRILL. This book was released on 2023-08-28 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a multi-authored book concerning the perceived threat and recorded increase of emerging pests and vector-borne diseases affecting man and animals in Europe. Historically, Europe suffered from numerous pests and vector-borne diseases, including yellow fever, malaria, plague and typhus. Introduction of hygienic measures, drugs and vector control caused the disappearance of many of these diseases from Europe. In the (sub)tropics, however, many of these diseases still thrive, causing serious health problems for humans and animals. Increased trade, leading to animal and human movement and climate change cause reason to assume that several of these diseases might become re-established or allow 'new' diseases and pests to be introduced in Europe. The recent outbreaks of bluetongue virus in North-western Europe highlights this concern, requiring an effective surveillance systems for the early detection of pests and vector-borne diseases. In 24 chapters this book provides examples of the most likely pests and diseases affecting man and animals in Europe, with emphasis on ecological factors favouring these diseases and methods for prevention and intervention. The authors are recognized experts in specific fields. All chapters are peer reviewed."

Epidemics in Modern Asia

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Publisher : Cambridge University Press
ISBN 13 : 1316546179
Total Pages : 379 pages
Book Rating : 4.3/5 (165 download)

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Book Synopsis Epidemics in Modern Asia by : Robert Peckham

Download or read book Epidemics in Modern Asia written by Robert Peckham and published by Cambridge University Press. This book was released on 2016-04-28 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemics have played a critical role in shaping modern Asia. Encompassing two centuries of Asian history, Robert Peckham explores the profound impact that infectious disease has had on societies across the region: from India to China and the Russian Far East. The book tracks the links between biology, history, and geopolitics, highlighting infectious disease's interdependencies with empire, modernization, revolution, nationalism, migration, and transnational patterns of trade. By examining the history of Asia through the lens of epidemics, Peckham vividly illustrates how society's material conditions are entangled with social and political processes, offering an entirely fresh perspective on Asia's transformation.

Manual of Security Sensitive Microbes and Toxins

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Author :
Publisher : CRC Press
ISBN 13 : 1466553987
Total Pages : 884 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Manual of Security Sensitive Microbes and Toxins by : Dongyou Liu

Download or read book Manual of Security Sensitive Microbes and Toxins written by Dongyou Liu and published by CRC Press. This book was released on 2014-04-08 with total page 884 pages. Available in PDF, EPUB and Kindle. Book excerpt: Security sensitive microbes (viruses, bacteria, fungi, and parasites) and toxins, which are often referred to as the select agents and toxins, have the capacity to cause serious illness and death in humans, animals, and plants. Throughout history, these microbes and toxins have been exploited in one form or another as biowarfare and bioterror agents that create fear and panic well beyond any actual physical damages they might cause. Manual of Security Sensitive Microbes and Toxins provides comprehensive, state-of-the-art coverage of microbes and toxins of biosecurity concern. The ultimate goal is to increase our awareness of these agents and enhance our preparedness against any future bio-emergencies. The book begins with an introduction containing a brief overview of the historical aspects of security sensitive microbes and toxins. This is followed by a concise summary of the current status in relation to the regulation of security sensitive microbes and toxins and a discussion of future development trends. The book is divided into seven parts: Microbes and Toxins Affecting Humans and Animals: Viruses Microbes and Toxins Affecting Human and Animals: Bacteria Microbes and Toxins Affecting Human and Animals: Fungus and Parasite Microbes and Toxins Affecting Human and Animals: Toxins Microbes Affecting Animals: Viruses Microbes Affecting Animals: Bacteria Microbes Affecting Plants Written by experts in the relevant areas of research, the chapters are authoritative reviews, each one covering a single microbe or toxin with respect to its classification, biology, epidemiology, pathogenesis, identification, diagnosis, treatment, and prevention. The chapters also discuss the limitations of our current knowledge and challenges relating to improved detection and control of the microbe or toxin.