New Synthetic Routes to Seleno- and Tellurorhodamine Photosensitizers for Photodynamic Therapy

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ISBN 13 :
Total Pages : 67 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis New Synthetic Routes to Seleno- and Tellurorhodamine Photosensitizers for Photodynamic Therapy by : Jacqueline Hill

Download or read book New Synthetic Routes to Seleno- and Tellurorhodamine Photosensitizers for Photodynamic Therapy written by Jacqueline Hill and published by . This book was released on 2013 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhodamine dyes with an N-methyltetrahydroquinoline replacing one dialkylamino group are termed half-julolidyl rhodamines. Selenium (Se) and tellurium (Te) analogues of the half-julolidyl dyes were synthesized as an improvement over the half-julolidyl sulfur (S) analogue for P-gp inhibition and for use as a photosensitizer in photodynamic therapy (PDT). The Se analogues showed an increased absorption maxima, larger extinction coefficients, and a largerquantum yield of singlet oxygen. Phototoxicity assays for PDT showed the presence of the amide/thioamide `switch' in P-gp transport rates. The thioamide dyes had improved P-gp inhibition over the amides and showed greater cytotoxic effects. The Se analogues were also testing in activated and resting T-cells for selective uptake in activated T-cells followed by selective depletion of the active T-cells for extracorporeal photopheresis. Assays showed that the amide analogues had greater selective uptake in activated and malignant cells than the thioamide analogues.

Synthesis of Selenopyrylium Photosensitizers for Photodynamic Therapy

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ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (465 download)

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Book Synopsis Synthesis of Selenopyrylium Photosensitizers for Photodynamic Therapy by : Teiah M. Moore

Download or read book Synthesis of Selenopyrylium Photosensitizers for Photodynamic Therapy written by Teiah M. Moore and published by . This book was released on 2001 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Imaging Primer

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Molecular Imaging Primer by : Sanjiv Sam Gambhir

Download or read book Molecular Imaging Primer written by Sanjiv Sam Gambhir and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cancer Nanotheranostics

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Publisher : Springer Nature
ISBN 13 : 3030762637
Total Pages : 379 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Cancer Nanotheranostics by : Muthupandian Saravanan

Download or read book Cancer Nanotheranostics written by Muthupandian Saravanan and published by Springer Nature. This book was released on 2021-10-05 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Nanotheranostics, Volume 2 continues the discussion of the important work being done in this field of cancer nanotechnology. The contents of these two volumes are explained in detail as follows. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials, and nano-antibodies. This important second volume discusses nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nanoerythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, safety of nanobiomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics. Volume 2 is a vital continuation of this two-volume set. Together, these two volumes create a comprehensive and unique examination of this important area of research.