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Author : Paul Grant Spoors
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (59 download)
Download or read book New Synthetic Approaches Towards the Synthesis of Morphine written by Paul Grant Spoors and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Denice M. Spero
Publisher :
ISBN 13 :
Total Pages : 276 pages
Book Rating : 4.:/5 (29 download)
Download or read book A Radical Cyclization Approach to the Synthesis of Morphine and Synthetic Approaches to Trialkoxyphthalic Acid Derivatives written by Denice M. Spero and published by . This book was released on 1988 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Cynthia Baker McGowan
Publisher :
ISBN 13 :
Total Pages : 96 pages
Book Rating : 4.:/5 (175 download)
Download or read book Approaches to the Synthesis of Morphine written by Cynthia Baker McGowan and published by . This book was released on 1980 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David Jude Harris
Publisher :
ISBN 13 :
Total Pages : 151 pages
Book Rating : 4.:/5 (947 download)
Download or read book Approaches to the Synthesis of Morphine written by David Jude Harris and published by . This book was released on 1982 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J.D. Phillipson
Publisher : Springer Science & Business Media
ISBN 13 : 3642701280
Total Pages : 315 pages
Book Rating : 4.6/5 (427 download)
Download or read book The Chemistry and Biology of Isoquinoline Alkaloids written by J.D. Phillipson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isoquinolines form one of the largest groups of plant alkaloids and they in clude a number of valuable clinical agents such as codeine, morphine, eme tine and tubocurarine. Research into different aspects of isoquinolines con tinues in profusion, attracting the talents of botanists, chemists, bioche mists, analysts, pharmacists and pharmacologists. Many of these aspects are of an interdisciplinary nature, and in April 1984, The Phytochemical Society of Europe arranged a 3-day symposium on The Chemistry and Bi ology of Isoquinoline Alkaloids in order to provide a forum for scientists of differing disciplines who are united by a common interest in this one class of natural product. Each chapter in this volume is based on a lecture given at this symposium. Attempts have been made to make the aims and objectives, experimental findings and conclusions reached, intelligible to scientists of differing backgrounds. The introductory chapter, which is mainly based on a historical discus sion, stresses that plants containing isoquinolines have proved to be both a boon and a curse to mankind. The Opium Poppy, Papaver somniferum, produces the medicinally used alkaloids morphine, codeine, noscapine and papaverine whilst it also continues to provide drugs of abuse, particularly morphine and its readily prepared O,O-diacetyl derivative, heroin. Numer ous other alkaloids have been isolated from other members of the Papaver acea, and a knowledge of their presence and distribution within the various species has proved a useful adjunct to systematic botanical studies.
Author : Hans-Joachim Knoelker
Publisher : Springer Science & Business Media
ISBN 13 : 3642255280
Total Pages : 268 pages
Book Rating : 4.6/5 (422 download)
Download or read book Alkaloid Synthesis written by Hans-Joachim Knoelker and published by Springer Science & Business Media. This book was released on 2012-01-13 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lycopodium Alkaloids: Isolation and Asymmetric Synthesis, by Mariko Kitajima and Hiromitsu Takayama.- Synthesis of Morphine Alkaloids and Derivatives, by Uwe Rinner and Tomas Hudlicky.- Indole Prenylation in Alkaloid Synthesis, by Thomas Lindel, Nils Marsch and Santosh Kumar Adla.- Marine Pyrroloiminoquinone Alkaloids, by Yasuyuki Kita and Hiromichi Fujioka.- Synthetic Studies on Amaryllidaceae and Other Terrestrially Derived Alkaloids, by Martin G. Banwell, Nadia Yuqian Gao, Brett D. Schwartz and Lorenzo V. White.- Synthesis of Pyrrole and Carbazole Alkaloids, by Ingmar Bauer and Hans-Joachim Knölker.-
Author : Barbara Yu-Fong Wan
Publisher :
ISBN 13 :
Total Pages : 106 pages
Book Rating : 4.:/5 (177 download)
Download or read book Approaches to the Synthesis of Morphine written by Barbara Yu-Fong Wan and published by . This book was released on 1987 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mark David Charles
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.:/5 (847 download)
Download or read book Synthetic Studies Towards a Total Synthesis of Morphine written by Mark David Charles and published by . This book was released on 2003 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sarathy Kesavan
Publisher :
ISBN 13 :
Total Pages : 164 pages
Book Rating : 4.:/5 (617 download)
Download or read book Synthetic Approach Towards Methyllycaconitine written by Sarathy Kesavan and published by . This book was released on 2004 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic synthesis, with the invention of new synthetic strategies and technologies, has evolved from largely empirical approaches for the preparation of relatively simple molecules to sophisticated strategies for the construction of molecules with considerable structural and functional complexity. Organic synthesis is employed to synthesize the natural product and its analogs for the discovery of new drugs. The development of new synthetic methodologies in the course of total synthesis is imperative for the efficient synthesis of drug candidates. Apart from the practical applications, the pursuit of efficient syntheses of complex natural products is both gratifying and truly enjoyable. Chapter One describes the development of annulation reaction for the construction of five-, six- and seven- membered rings. Chapter Two describes a direct approach to the synthesis of methyllycaconitine, a representative of the aconitine alkaloids. The numbering of the compounds, schemes and references are independent in each section.
Author : David C. Blakemore
Publisher : Royal Society of Chemistry
ISBN 13 : 1849738033
Total Pages : 474 pages
Book Rating : 4.8/5 (497 download)
Download or read book Synthetic Methods in Drug Discovery written by David C. Blakemore and published by Royal Society of Chemistry. This book was released on 2016 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of available synthetic methods can be overwhelming. In order to create novel motifs and templates which confer new and potentially valuable drug-like properties, it is important to know which synthetic methodologies will give the best results. Similarly, which methodologies are used to progress potential drug candidates from leads through the development process? What are the current industrial research problems and how can they be resolved in an industrial setting? This book highlights key methods that have real impact in drug discovery and facilitate delivery of drug molecules. Synthetic Methods in Drug Discovery Volume 1 focuses on the hugely important area of transition metal mediated methods used in industry. Current methods of importance such as the Suzuki-Miyaura coupling, Buchwald-Hartwig couplings and CH activation are discussed. In addition, exciting emerging areas such as decarboxylative coupling, and the uses of iron and nickel in coupling reactions are also covered. This book provides both academic and industrial perspectives on some key reactions giving the reader an excellent overview of the techniques used in modern synthesis. Reaction types are conveniently framed in the context of their value to industry and the challenges and limitations of methodologies are discussed with relevant illustrative examples. Edited and authored by leading scientists from both academia and industry, this book will be a valuable reference for all chemists involved in drug discovery as well as postgraduate students in medicinal chemistry.
Author : Joseph Fadesire Ajao
Publisher :
ISBN 13 :
Total Pages : 300 pages
Book Rating : 4.:/5 (918 download)
Download or read book Approaches to the Synthesis of Morphine Analogues written by Joseph Fadesire Ajao and published by . This book was released on 1983 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Frank Stappenbeck
Publisher :
ISBN 13 :
Total Pages : 380 pages
Book Rating : 4.:/5 (367 download)
Download or read book Synthetic Studies on Alkaloids written by Frank Stappenbeck and published by . This book was released on 1994 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tomas Hudlicky
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.X/5 (3 download)
Download or read book The Way of Synthesis written by Tomas Hudlicky and published by Wiley-VCH. This book was released on 2007-09-04 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)
Author : Bryce Pardo
Publisher :
ISBN 13 : 9781977403384
Total Pages : 0 pages
Book Rating : 4.4/5 (33 download)
Download or read book The Future of Fentanyl and Other Synthetic Opioids written by Bryce Pardo and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deaths involving synthetic opioids, such as fentanyl, increased from roughly 3,000 in 2013 to more than 30,000 in 2018. This book provides readers with insights intended to improve their understanding of the synthetic opioid problem.
Author : Michael P. Hinton
Publisher :
ISBN 13 :
Total Pages : 143 pages
Book Rating : 4.:/5 (835 download)
Download or read book A Novel Approach to the Synthesis of Morphine written by Michael P. Hinton and published by . This book was released on 1986 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Janina Beck
Publisher : Logos Verlag Berlin GmbH
ISBN 13 : 3832551468
Total Pages : 272 pages
Book Rating : 4.8/5 (325 download)
Download or read book Development of New Synthetic Approaches towards the Anthraquinone-Xanthone Heterodimeric Structure of Beticolin 0 written by Janina Beck and published by Logos Verlag Berlin GmbH. This book was released on 2020-09-15 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mycotoxins are fungal secondary metabolites exhibiting adverse effects on humans, animals as well as crops, resulting in diseases and economic loss. Beticolins are mycotoxins produced by the fungus Cercospora beticola which is responsible for cercosporiosis, commonly known as leaf spot disease, causing heavy damages to crops worldwide. In order to study the mechanism of action of these biologically active compounds, this thesis aimed at the development of synthetic approaches towards the highly complex polycyclic scaffold of beticolins. Beticolins consist of a chlorinated tetrahydroxanthone linked to an anthraquinone subunit via a unique bicyclo[3.2.2]nonane ring system. A facile route towards naphthoquinone derivatives and subsequent Diels-Alder cycloadditions with functionalized dienes afforded a highly functionalized anthraquinone subunit of beticolin 0. For the installation of a tetrahydroxanthone subunit, a synthetic route was elaborated. With the obtained anthraquinone derivatives intramolecular couplings were performed under different conditions, to facilitate the construction of the bicyclo[3.2.2]nonane ring system. The formation of the desired scaffold turned out to be challenging, however a variety of novel bicyclo[3.3.1]systems was obtained, representing interesting scaffolds. During a research stay at the University of Copenhagen, the functionalization of helical beta-peptoids was examined. Peptidomimetics adopting three-dimensional structures with well-defined display of functional groups while being resistant to proteolysis, are of interest for the development of foldamers with a desired function.
Author : Sonja Keller Gross
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (769 download)
Download or read book An Approach to the Synthesis of Morphine written by Sonja Keller Gross and published by . This book was released on 1954 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
