New Strategies in the Treatment of Gastrointestinal Tumors

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (641 download)

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Book Synopsis New Strategies in the Treatment of Gastrointestinal Tumors by :

Download or read book New Strategies in the Treatment of Gastrointestinal Tumors written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

New immunotherapy strategies and related therapeutic targets for gastrointestinal malignancies

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Publisher : Frontiers Media SA
ISBN 13 : 2832544444
Total Pages : 204 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis New immunotherapy strategies and related therapeutic targets for gastrointestinal malignancies by : Chi Chun Wong

Download or read book New immunotherapy strategies and related therapeutic targets for gastrointestinal malignancies written by Chi Chun Wong and published by Frontiers Media SA. This book was released on 2024-03-13 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, the treatment options for gastrointestinal malignancies mainly include surgery, chemotherapy, radiotherapy, and molecular targeted therapy, etc. Drug therapy is one of the main treatments for patients with advanced stages, but the efficacy of chemotherapy seems to have reached a plateau, and the progress of traditional molecular targeted therapy is relatively slow. In addition, the benefits of the current chemotherapy combined with targeted therapy for patients with advanced stages of gastrointestinal malignancies are still not satisfactory. Tumor immunotherapy is an emerging therapeutic approach and is a current research hotspot, and there are hopes that immunotherapy can help further improve the prognosis and quality of life for patients with gastrointestinal malignancies. At the same time, potential targets of immunotherapeutic drugs and prognostic biomarkers for gastrointestinal malignancies have been less studied than other common cancers, such as lung cancer. Prognostic biomarker studies are the beginning of exploring new drug targets and revealing potential mechanisms of tumor progression. Immunotherapies, particularly PD1 or PD-L1 antagonists, have demonstrated effective therapeutic efficacy against various types of cancer. To date, many PD1 drugs are available for cancer treatment, and more than 100 PD1 drugs are in clinical trials. However, the question of how to screen sensitive patients and predict the efficacy of immunotherapy remains unresolved. In addition, predictive biomarkers and treatment guidelines for immunotherapy of gastrointestinal malignancies have hardly been studied.

Handbook of Gastrointestinal Cancers

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Publisher : Springer Publishing Company
ISBN 13 : 0826138136
Total Pages : 516 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Handbook of Gastrointestinal Cancers by : Tanios Bekaii-Saab, MD

Download or read book Handbook of Gastrointestinal Cancers written by Tanios Bekaii-Saab, MD and published by Springer Publishing Company. This book was released on 2019-08-12 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower gastrointestinal tract. Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. The handbook focuses on treatment strategies and approaches to cancerous gastrointestinal tumors that are transforming the recent oncological landscape, including expert-given guidance on methods such as neoadjuvant and adjuvant chemotherapy, surgical transplant, radiation therapy, molecular diagnostic testing leading to molecularly targeted therapy, and immunotherapy. With so many advances in the current field, it is increasingly difficult for early-career practitioners to grasp the entirety of practices and for seasoned oncologists to keep up with newly approved therapies, side effects to treatments, and special clinical management considerations, but this handbook addresses it all. Organized by major gastrointestinal disease sites and featuring “How I Treat” case vignettes from world experts for common and uncommon management considerations, the handbook brings an experience-based perspective to these tough-to-treat areas. The treatment strategies and applications set forth in the chapters are pertinent to situations and decision-making encountered in practice. Handbook of Gastrointestinal Cancers is a valuable resource for medical oncologists, radiation oncologists, and surgeons treating and managing gastrointestinal cancers as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource. KEY FEATURES: Provides treatment plans and recommendations for each stage of a range of gastrointestinal cancers, including colorectal, pancreatic, and hepatocellular cancers plus more Includes “How I Treat” patient vignettes told from the physician’s point of view within each clinical chapter Outlines special considerations for the elderly and for survivors of gastrointestinal cancers Highlights important clinical guidance on nutritional and palliative concerns commonly seen in patients with gastrointestinal cancers

Management of Gastric Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 1461538823
Total Pages : 405 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Management of Gastric Cancer by : Paul H. Sugarbaker

Download or read book Management of Gastric Cancer written by Paul H. Sugarbaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases

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Publisher : World Scientific
ISBN 13 : 9813148586
Total Pages : 458 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases by : Chi-hin Cho

Download or read book Therapeutic Targets For Inflammation And Cancer: Novel Therapies For Digestive Diseases written by Chi-hin Cho and published by World Scientific. This book was released on 2017-04-20 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book deals with both inflammation and cancer in a single source of publication. They are seldom grouped together although it has been known that both diseases are closely associated, particularly in the gastrointestinal tract and liver. As the book touches on two such major areas of diseases in humans, it should be of interest to a wider audience of researchers and readers. It is noted that the book combines the effort of both basic scientists and clinicians from different countries with extensive experiences in molecular biology and clinical practice to unveil the most updated picture of the pathogenesis and therapeutic strategies in the treatment of inflammation and cancer in the digestive tract. In this regard, potential pathogenic modulators and also therapeutic options are widely discussed. These types of information would definitely broaden our knowledge in better understanding these diseases.

New Developments in Targeted Treatment Strategies for Colorectal Cancer

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Publisher :
ISBN 13 :
Total Pages : 36 pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis New Developments in Targeted Treatment Strategies for Colorectal Cancer by : Axel Grothey

Download or read book New Developments in Targeted Treatment Strategies for Colorectal Cancer written by Axel Grothey and published by . This book was released on 2007 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Staging Laparoscopy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642562906
Total Pages : 206 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Staging Laparoscopy by : P. Hohenberger

Download or read book Staging Laparoscopy written by P. Hohenberger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

Gastric Cancer: the 25-year R-Evolution

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Publisher : Springer
ISBN 13 : 9783030731571
Total Pages : 0 pages
Book Rating : 4.7/5 (315 download)

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Book Synopsis Gastric Cancer: the 25-year R-Evolution by : Giovanni de Manzoni

Download or read book Gastric Cancer: the 25-year R-Evolution written by Giovanni de Manzoni and published by Springer. This book was released on 2021-09-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.

Adenocarcinoma of the Prostate

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Publisher : Springer Science & Business Media
ISBN 13 : 1447113985
Total Pages : 363 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Adenocarcinoma of the Prostate by : Andrew W. Bruce

Download or read book Adenocarcinoma of the Prostate written by Andrew W. Bruce and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carcinoma of the prostate increasingly dominates the attention of urologists for both scientific and clinical reasons. The search for an explanation and the prediction of the variable behaviour of the malignant prostatic cell continues unabated. The search for more precise tumour staging and more effective treatment is equally vigorous. Editors Andrew Bruce and John Trachtenberg have assembled acknowledged leaders in prostate cancer to present those areas of direct interest to the clinician. There are a number of other topics that might have been considered but most of these, such as experimental tumour models or biochemical factors affecting cell growth, still lack immediate application for the clinician. Carcinoma of the prostate continues to have its highest incidence in the western world, and the difference in comparison with the incidence in the Far East appears to be real and not masked by diagnostic or other factors. A number of other epidemiological aspects need careful analysis: Is the incidence increasing? Is the survival improving? Is the prognosis worse in the younger patient? Epidemiological data are easily misused and misinterpreted so that a precise analysis of the known facts makes an important opening chapter to this book.

Soft Tissue and Bone Sarcoma

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Publisher : MDPI
ISBN 13 : 3906980464
Total Pages : 157 pages
Book Rating : 4.9/5 (69 download)

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Book Synopsis Soft Tissue and Bone Sarcoma by : Edwin Choy

Download or read book Soft Tissue and Bone Sarcoma written by Edwin Choy and published by MDPI. This book was released on 2018-10-08 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Soft Tissue and Bone Sarcoma" that was published in Cancers

New Strategies For Treatment Of Hereditary

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Publisher :
ISBN 13 : 9784893701299
Total Pages : pages
Book Rating : 4.7/5 (12 download)

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Book Synopsis New Strategies For Treatment Of Hereditary by : Baba

Download or read book New Strategies For Treatment Of Hereditary written by Baba and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Preoperative eva

Perioperative Chemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642824323
Total Pages : 170 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Perioperative Chemotherapy by : U. Metzger

Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

New Perspectives in the Treatment of Gastrointestinal Tumors

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Publisher :
ISBN 13 :
Total Pages : 42 pages
Book Rating : 4.:/5 (924 download)

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Book Synopsis New Perspectives in the Treatment of Gastrointestinal Tumors by :

Download or read book New Perspectives in the Treatment of Gastrointestinal Tumors written by and published by . This book was released on 2000 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research and Clinical Applications of Targeting Gastric Neoplasms

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Publisher : Elsevier
ISBN 13 : 0323855636
Total Pages : 370 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Research and Clinical Applications of Targeting Gastric Neoplasms by : Brendan Jenkins

Download or read book Research and Clinical Applications of Targeting Gastric Neoplasms written by Brendan Jenkins and published by Elsevier. This book was released on 2021-07-23 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and Clinical Applications of Targeting Gastric Neoplasms provides a comprehensive overview of gastrointestinal cancers, covering preclinical research and clinical findings related to risk factors, current treatment regimens (including immunotherapy), screening/detection methods, etiology of disease, precision medicine and future perspectives. Gastrointestinal cancers rank among the most lethal and common worldwide, and as such, there is intense research into their diverse causes and treatment options. This reference provides a consolidation of the research, making it a perfect resource for basic science and clinical researchers as well as oncologists who work in gastroenterology and GI tract cancer fields. Provides comprehensive coverage of preclinical research and the clinical aspects of gastric cancer Presents future perspectives from leading researchers in the field who provide the potential for furthering research topics Combines the expertise of researchers in GI tracts, cancer, immunity, immunology, infectious disease and microbiology for an interdisciplinary approach

Gastrointestinal Cancer Atlas for Endoscopic Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 4431881662
Total Pages : 138 pages
Book Rating : 4.4/5 (318 download)

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Book Synopsis Gastrointestinal Cancer Atlas for Endoscopic Therapy by : Rikiya Fujita

Download or read book Gastrointestinal Cancer Atlas for Endoscopic Therapy written by Rikiya Fujita and published by Springer Science & Business Media. This book was released on 2009-03-08 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since a number of mucosal digestive tract cancer detected has increased in recent years with an advance of endoscopic instruments, endoscopic treatment of digestive tract cancer is widely spread in Japan but not in other countries. Minute cancers seem to have own characteristic mucosal signs compared with benign lesions. Therefore, strategies, those are different in Japan from other countries, of endoscopic diagnosis are very important. The cancer institute hospital of JFCR (Japan foundation of cancer research) is one of the top institutions which do the best endoscopic treatment in Japan. This book is expected to be the first valuable atlas in which the abundant experiences of this hospital offer beautiful photographs of minute cancers without any scars of biopsies which change aspects of original lesions. This book also offer pictures of magnifying endoscopy using NBI (Narrow Band Imaging) and pathological findings.

Colon Cancer Diagnosis and Therapy

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Publisher : Springer Nature
ISBN 13 : 3030646688
Total Pages : 453 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Colon Cancer Diagnosis and Therapy by : Naveen Kumar Vishvakarma

Download or read book Colon Cancer Diagnosis and Therapy written by Naveen Kumar Vishvakarma and published by Springer Nature. This book was released on 2021-06-04 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer (CRC) is a major global health challenge as the third leading cause for cancer related mortalities worldwide. Despite advances in therapeutic strategies, the five-year survival rate for CRC patients has remained the same over time due to the fact that patients are often diagnosed in advanced metastatic stages. Drug resistance is another common reason for poor prognosis. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early stage diagnosis. This book is the second of three volumes on recent developments in colorectal diagnosis and therapy. Each volume can be read on its own, or together. Each volume focuses on different novel therapeutic advances, biomarkers, and identifies therapeutic targets for treatment. Written by leading international experts in the field, coverage addresses the role of diet habits and lifestyle in reducing gastrointestinal disorders and incidence of CRC. Chapters discuss current and future diagnostic and therapeutic options for colorectal cancer patients, focusing on immunotherapeutics, nanomedicine, biomarkers, and dietary factors for the effective management of colon cancer.

GISTs - Gastrointestinal Stromal Tumors

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Publisher : Springer Science & Business Media
ISBN 13 : 8847018692
Total Pages : 129 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis GISTs - Gastrointestinal Stromal Tumors by : Elisabetta de Lutio di Castelguidone

Download or read book GISTs - Gastrointestinal Stromal Tumors written by Elisabetta de Lutio di Castelguidone and published by Springer Science & Business Media. This book was released on 2011-10-26 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a complete overview of the diagnosis and treatment of gastrointestinal stromal tumors (GISTs). It has been conceived to be both a detailed guide for clinical practice and an updated reference for all those involved in the evaluation of GISTs imaging. The publication provides comprehensive descriptions of the full range of common imaging and non imaging techniques used in the diagnosis and followup of GISTs. Techniques reviewed include: Conventional radiography· Endoscopy and endoscopic ultrasound· Conventional, color-Doppler and contrast-enhanced ultrasound· Computed tomography· Magnetic resonance imaging, and· Contrast-enhanced PET/CT imaging. Both medical and surgical treatment strategies are also fully reviewed. Finally, the book concludes with a chapter that aims to stimulate widespread interest in the formation of new GISTs Units. Written by experts in the field, the book is enriched throughout by numerous black-and-white and color images, making it an invaluable source of information as well as an indispensable guide to interpreting images for radiologists, gastroenterologists, pathologists, oncologists and surgeons.