New Frontiers of Biostatistics and Bioinformatics

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Author :
Publisher : Springer
ISBN 13 : 3319993895
Total Pages : 463 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis New Frontiers of Biostatistics and Bioinformatics by : Yichuan Zhao

Download or read book New Frontiers of Biostatistics and Bioinformatics written by Yichuan Zhao and published by Springer. This book was released on 2018-12-05 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is comprised of presentations delivered at the 5th Workshop on Biostatistics and Bioinformatics held in Atlanta on May 5-7, 2017. Featuring twenty-two selected papers from the workshop, this book showcases the most current advances in the field, presenting new methods, theories, and case applications at the frontiers of biostatistics, bioinformatics, and interdisciplinary areas. Biostatistics and bioinformatics have been playing a key role in statistics and other scientific research fields in recent years. The goal of the 5th Workshop on Biostatistics and Bioinformatics was to stimulate research, foster interaction among researchers in field, and offer opportunities for learning and facilitating research collaborations in the era of big data. The resulting volume offers timely insights for researchers, students, and industry practitioners.

New Developments in Biostatistics and Bioinformatics

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Publisher :
ISBN 13 : 9814469092
Total Pages : pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis New Developments in Biostatistics and Bioinformatics by :

Download or read book New Developments in Biostatistics and Bioinformatics written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

New Developments in Biostatistics and Bioinformatics

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Publisher :
ISBN 13 : 9787894236333
Total Pages : 272 pages
Book Rating : 4.2/5 (363 download)

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Book Synopsis New Developments in Biostatistics and Bioinformatics by : Jianqing Fan;Xihong Lin;Jun S. Liu

Download or read book New Developments in Biostatistics and Bioinformatics written by Jianqing Fan;Xihong Lin;Jun S. Liu and published by . This book was released on with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of recent developments in biostatistics and bioinformatics. Written by active researchers in these emerging areas, it is intended to give graduate students and new researchers an idea of where the frontiers of biostatistics and bioinformatics are as well as a forum to learn common techniques in use, so that they can advance the fields via developing new techniques and new results. Extensive references are provided so that researchers can follow the threads to learn more comprehensively what the literature is and to conduct their own research. In particulars, the book covers three important and rapidly advancing topics in biostatistics: analysis of survival and longitudinal data, statistical methods for epidemiology, and bioinformatics.

New Developments in Biostatistics and Bioinformatics

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Author :
Publisher : World Scientific
ISBN 13 : 9812837442
Total Pages : 295 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis New Developments in Biostatistics and Bioinformatics by : Jianqing Fan

Download or read book New Developments in Biostatistics and Bioinformatics written by Jianqing Fan and published by World Scientific. This book was released on 2009 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an overview of recent developments in biostatistics and bioinformatics. Written by active researchers in these emerging areas, it is intended to give graduate students and new researchers an idea of where the frontiers of biostatistics and bioinformatics are as well as a forum to learn common techniques in use, so that they can advance the fields via developing new techniques and new results. Extensive references are provided so that researchers can follow the threads to learn more comprehensively what the literature is and to conduct their own research. In particulars, the book covers three important and rapidly advancing topics in biostatistics: analysis of survival and longitudinal data, statistical methods for epidemiology, and bioinformatics.

Handbook of Statistical Bioinformatics

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Author :
Publisher : Springer Nature
ISBN 13 : 3662659026
Total Pages : 406 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Handbook of Statistical Bioinformatics by : Henry Horng-Shing Lu

Download or read book Handbook of Statistical Bioinformatics written by Henry Horng-Shing Lu and published by Springer Nature. This book was released on 2022-12-08 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, this handbook collects authoritative contributions on modern methods and tools in statistical bioinformatics with a focus on the interface between computational statistics and cutting-edge developments in computational biology. The three parts of the book cover statistical methods for single-cell analysis, network analysis, and systems biology, with contributions by leading experts addressing key topics in probabilistic and statistical modeling and the analysis of massive data sets generated by modern biotechnology. This handbook will serve as a useful reference source for students, researchers and practitioners in statistics, computer science and biological and biomedical research, who are interested in the latest developments in computational statistics as applied to computational biology.

Statistical Advances in the Biomedical Sciences

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0470181192
Total Pages : 623 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Statistical Advances in the Biomedical Sciences by : Atanu Biswas

Download or read book Statistical Advances in the Biomedical Sciences written by Atanu Biswas and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Most Comprehensive and Cutting-Edge Guide to Statistical Applications in Biomedical Research With the increasing use of biotechnology in medical research and the sophisticated advances in computing, it has become essential for practitioners in the biomedical sciences to be fully educated on the role statistics plays in ensuring the accurate analysis of research findings. Statistical Advances in the Biomedical Sciences explores the growing value of statistical knowledge in the management and comprehension of medical research and, more specifically, provides an accessible introduction to the contemporary methodologies used to understand complex problems in the four major areas of modern-day biomedical science: clinical trials, epidemiology, survival analysis, and bioinformatics. Composed of contributions from eminent researchers in the field, this volume discusses the application of statistical techniques to various aspects of modern medical research and illustrates how these methods ultimately prove to be an indispensable part of proper data collection and analysis. A structural uniformity is maintained across all chapters, each beginning with an introduction that discusses general concepts and the biomedical problem under focus and is followed by specific details on the associated methods, algorithms, and applications. In addition, each chapter provides a summary of the main ideas and offers a concluding remarks section that presents novel ideas, approaches, and challenges for future research. Complete with detailed references and insight on the future directions of biomedical research, Statistical Advances in the Biomedical Sciences provides vital statistical guidance to practitioners in the biomedical sciences while also introducing statisticians to new, multidisciplinary frontiers of application. This text is an excellent reference for graduate- and PhD-level courses in various areas of biostatistics and the medical sciences and also serves as a valuable tool for medical researchers, statisticians, public health professionals, and biostatisticians.

Contemporary Biostatistics with Biopharmaceutical Applications

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Author :
Publisher : Springer
ISBN 13 : 303015310X
Total Pages : 339 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Contemporary Biostatistics with Biopharmaceutical Applications by : Lanju Zhang

Download or read book Contemporary Biostatistics with Biopharmaceutical Applications written by Lanju Zhang and published by Springer. This book was released on 2019-07-11 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents current research in biostatistics with emphasis on biopharmaceutical applications. Featuring contributions presented at the 2017 ICSA Applied Statistics Symposium held in Chicago, IL on June 25 to 28, 2017, this book explores timely topics that have a high potential impact on statistical methodology and future research in biostatistics and biopharmaceuticals. The theme of this conference was Statistics for a New Generation: Challenges and Opportunities, in recognition of the advent of a new generation of statisticians. The conference attracted statisticians working in academia, government, and industry; domestic and international statisticians. From the conference, the editors selected 28 high-quality presentations and invited the speakers to prepare full chapters for this book. These contributions are divided into four parts: Part I Biostatistical Methodology, Part II Statistical Genetics and Bioinformatics, Part III Regulatory Statistics, and Part IV Biopharmaceutical Research and Applications. Featuring contributions on topics such as statistics in genetics, bioinformatics, biostatistical methodology, and statistical computing, this book is beneficial to researchers, academics, practitioners and policy makers in biostatistics and biopharmaceuticals.

New Frontiers of Multidisciplinary Research in STEAM-H (Science, Technology, Engineering, Agriculture, Mathematics, and Health)

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Author :
Publisher : Springer
ISBN 13 : 3319077554
Total Pages : 389 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis New Frontiers of Multidisciplinary Research in STEAM-H (Science, Technology, Engineering, Agriculture, Mathematics, and Health) by : Bourama Toni

Download or read book New Frontiers of Multidisciplinary Research in STEAM-H (Science, Technology, Engineering, Agriculture, Mathematics, and Health) written by Bourama Toni and published by Springer. This book was released on 2014-09-25 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly multidisciplinary volume contains contributions from leading researchers in STEAM-H disciplines (Science, Technology, Engineering, Agriculture, Mathematics and Health). The volume explores new frontiers in multidisciplinary research, including: the mathematics of cardiac arrhythmia; brain research on working memory; penalized ordinal regression to classify melanoma skin samples; forecasting of time series data; dynamics of niche models; analysis of chemical moieties as anticancer agents; study of gene locus control regions; qualitative mathematical modelling; convex quadrics and group circle systems; remanufacturing planning and control; complexity reduction of functional differential equations; computation of viscous interfacial motion; and differentiation in human pluripotent stem cells. An extension of a seminar series at Virginia State University, the collection is intended to foster student interest and participation in interdisciplinary research and to stimulate new research. The content will be of interest to a broad spectrum of scientists, mathematicians and research students working in interdisciplinary fields including the biosciences, mathematics, engineering, neurosciences and behavioral sciences.

Frontiers of Biostatistical Methods and Applications in Clinical Oncology

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Author :
Publisher : Springer
ISBN 13 : 981100126X
Total Pages : 438 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Frontiers of Biostatistical Methods and Applications in Clinical Oncology by : Shigeyuki Matsui

Download or read book Frontiers of Biostatistical Methods and Applications in Clinical Oncology written by Shigeyuki Matsui and published by Springer. This book was released on 2017-10-03 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art of biostatistical methods and their applications in clinical oncology. Many methodologies established today in biostatistics have been brought about through its applications to the design and analysis of oncology clinical studies. This field of oncology, now in the midst of evolution owing to rapid advances in biotechnologies and cancer genomics, is becoming one of the most promising disease fields in the shift toward personalized medicine. Modern developments of diagnosis and therapeutics of cancer have also been continuously fueled by recent progress in establishing the infrastructure for conducting more complex, large-scale clinical trials and observational studies. The field of cancer clinical studies therefore will continue to provide many new statistical challenges that warrant further progress in the methodology and practice of biostatistics. This book provides a systematic coverage of various stages of cancer clinical studies. Topics from modern cancer clinical trials include phase I clinical trials for combination therapies, exploratory phase II trials with multiple endpoints/treatments, and confirmative biomarker-based phase III trials with interim monitoring and adaptation. It also covers important areas of cancer screening, prognostic analysis, and the analysis of large-scale molecular data in the era of big data.

Statistical Modelling in Biostatistics and Bioinformatics

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Publisher : Springer Science & Business Media
ISBN 13 : 3319045792
Total Pages : 250 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Statistical Modelling in Biostatistics and Bioinformatics by : Gilbert MacKenzie

Download or read book Statistical Modelling in Biostatistics and Bioinformatics written by Gilbert MacKenzie and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents selected papers on statistical model development related mainly to the fields of Biostatistics and Bioinformatics. The coverage of the material falls squarely into the following categories: (a) Survival analysis and multivariate survival analysis, (b) Time series and longitudinal data analysis, (c) Statistical model development and (d) Applied statistical modelling. Innovations in statistical modelling are presented throughout each of the four areas, with some intriguing new ideas on hierarchical generalized non-linear models and on frailty models with structural dispersion, just to mention two examples. The contributors include distinguished international statisticians such as Philip Hougaard, John Hinde, Il Do Ha, Roger Payne and Alessandra Durio, among others, as well as promising newcomers. Some of the contributions have come from researchers working in the BIO-SI research programme on Biostatistics and Bioinformatics, centred on the Universities of Limerick and Galway in Ireland and funded by the Science Foundation Ireland under its Mathematics Initiative.

The New Frontier of Network Physiology: From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889714357
Total Pages : 842 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The New Frontier of Network Physiology: From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems by : Plamen Ch. Ivanov

Download or read book The New Frontier of Network Physiology: From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems written by Plamen Ch. Ivanov and published by Frontiers Media SA. This book was released on 2022-02-17 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Bioinformatics, Biostatistics and Omic Sciences

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Publisher : Bentham Science Publishers
ISBN 13 : 9811481784
Total Pages : 148 pages
Book Rating : 4.8/5 (114 download)

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Book Synopsis Advances in Bioinformatics, Biostatistics and Omic Sciences by : Luigi Donato

Download or read book Advances in Bioinformatics, Biostatistics and Omic Sciences written by Luigi Donato and published by Bentham Science Publishers. This book was released on 2020-11-30 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics, and by extension omic sciences – the collective disciplines that are dependent on the use of extensive datasets of biological information – present a challenge of data management for researchers all over the world. Big data collected as part of research projects and experiments can be complex, with several kinds of variables involved. Coupled with continuously changing bioinformatics and information technology tools, there is a need to bring a multidisciplinary approach into these fields. Advances in Bioinformatics, Biostatistics and Omic Sciences attempts to realize an integrated approach between all omic sciences, exploring innovative bioinformatics and biostatistical methodologies which enable researchers to unveil hidden sides of biological phenomena. This volume presents reviews on the following topics which give a glimpse of recent advances in the field: - New Integrated Mitochondrial DNA Bioinformatics Pipeline to Improve Quality Assessment of Putative Pathogenic Variants from NGS Experiments - Variant Calling on RNA Sequencing Data: State of Art and Future Perspectives - An innovative Gene Prioritization Pipeline for WES analyses - New Integrated Differential Expression Approach for RNA-Seq Data Analysis - Innovations in Data Visualization for Straightforward Interpretation of Nucleic Acid Omics Outcomes This volume serves as a guide for graduate students in bioinformatics as well as researchers planning new projects as a part of their professional and academic activities.

Computational Intelligence Methods for Bioinformatics and Biostatistics

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Publisher : Springer
ISBN 13 : 3319678345
Total Pages : 249 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Computational Intelligence Methods for Bioinformatics and Biostatistics by : Andrea Bracciali

Download or read book Computational Intelligence Methods for Bioinformatics and Biostatistics written by Andrea Bracciali and published by Springer. This book was released on 2017-10-14 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 13th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2016, held in Stirling, UK, in September 2016. The 19 revised full papers and 6 keynotes abstracts presented were carefully reviewed and selected from 61 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medicalinformatics, computational approaches to life sciences in general

Statistical Methods in Bioinformatics

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Publisher : Springer Science & Business Media
ISBN 13 : 0387266488
Total Pages : 598 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Statistical Methods in Bioinformatics by : Warren J. Ewens

Download or read book Statistical Methods in Bioinformatics written by Warren J. Ewens and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods. The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized. The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text. Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science. Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999. Comments on the first edition: "This book would be an ideal text for a postgraduate course...[and] is equally well suited to individual study.... I would recommend the book highly." (Biometrics) "Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces." (Naturwissenschaften) "The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details." (Journal American Statistical Association) "The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book." (Metrika)

Bioinformatics and Computational Biology Solutions Using R and Bioconductor

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387293620
Total Pages : 478 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Bioinformatics and Computational Biology Solutions Using R and Bioconductor by : Robert Gentleman

Download or read book Bioinformatics and Computational Biology Solutions Using R and Bioconductor written by Robert Gentleman and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

Contemporary Biostatistics with Biopharmaceutical Applications

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Author :
Publisher :
ISBN 13 : 9783030153113
Total Pages : 336 pages
Book Rating : 4.1/5 (531 download)

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Book Synopsis Contemporary Biostatistics with Biopharmaceutical Applications by : Lanju Zhang

Download or read book Contemporary Biostatistics with Biopharmaceutical Applications written by Lanju Zhang and published by . This book was released on 2019 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents current research in biostatistics with emphasis on biopharmaceutical applications. Featuring contributions presented at the 2017 ICSA Applied Statistics Symposium held in Chicago, IL on June 25 to 28, 2017, this book explores timely topics that have a high potential impact on statistical methodology and future research in biostatistics and biopharmaceuticals. The theme of this conference was Statistics for A New Generation: Challenges and Opportunities, in recognition of the advent of a new generation of statisticians. The conference attracted statisticians working in academia, government, and industry; domestic and international statisticians. From the conference, the editors selected 28 high-quality presentations and invited the speakers to prepare full chapters for this book. These contributions are divided into four parts: Part I Biostatistical Methodology, Part II Statistical Genetics and Bioinformatics, Part III Regulatory Statistics, and Part IV Biopharmaceutical Research and Applications. Featuring contributions on topics such as statistics in genetics, bioinformatics, biostatistical methodology, and statistical computing, this book is beneficial to researchers, academics, practitioners and policy makers in biostatistics and biopharmaceuticals.

Statistical Methods in Bioinformatics

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Author :
Publisher : Springer
ISBN 13 : 9780387516059
Total Pages : 0 pages
Book Rating : 4.5/5 (16 download)

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Book Synopsis Statistical Methods in Bioinformatics by : Warren J. Ewens

Download or read book Statistical Methods in Bioinformatics written by Warren J. Ewens and published by Springer. This book was released on 2008-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods. The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized. The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text. Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science. Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999. Comments on the first edition: "This book would be an ideal text for a postgraduate course...[and] is equally well suited to individual study.... I would recommend the book highly." (Biometrics) "Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces." (Naturwissenschaften) "The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details." (Journal American Statistical Association) "The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book." (Metrika)