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Author : Paul D. O'Malley
Publisher : Nova Science Publishers
ISBN 13 : 9781628088182
Total Pages : 264 pages
Book Rating : 4.0/5 (881 download)
Download or read book New Developments in Sickle Cell Disease Research written by Paul D. O'Malley and published by Nova Science Publishers. This book was released on 2014-05-14 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul D. O'Malley
Publisher : Nova Publishers
ISBN 13 : 9781594547928
Total Pages : 266 pages
Book Rating : 4.5/5 (479 download)
Download or read book New Developments in Sickle Cell Disease Research written by Paul D. O'Malley and published by Nova Publishers. This book was released on 2006 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Samir K. Ballas
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331834
Total Pages : 1004 pages
Book Rating : 4.4/5 (963 download)
Download or read book Sickle Cell Pain written by Samir K. Ballas and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 1004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sickle Cell Pain is a panoramic, in-depth exploration of every scientific, human, and social dimension of this cruel disease. This comprehensive, definitive work is unique in that it is the only book devoted to sickle cell pain, as opposed to general aspects of the disease. The 752-page book links sickle cell pain to basic, clinical, and translational research, addressing various aspects of sickle pain from molecular biology to the psychosocial aspects of the disease. Supplemented with patient narratives, case studies, and visual art, Sickle Cell Pain’s scientific rigor extends through its discussion of analgesic pharmacology, including abuse-deterrent formulations. The book also addresses in great detail inequities in access to care, stereotyping and stigmatization of patients, the implications of rapidly evolving models of care, and recent legislation and litigation and their consequences.
Author : Chaim Hershko
Publisher : Springer Science & Business Media
ISBN 13 : 1461505933
Total Pages : 275 pages
Book Rating : 4.4/5 (615 download)
Download or read book Iron Chelation Therapy written by Chaim Hershko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).
Author : Anjana Munshi
Publisher : BoD – Books on Demand
ISBN 13 : 9535121987
Total Pages : 198 pages
Book Rating : 4.5/5 (351 download)
Download or read book Inherited Hemoglobin Disorders written by Anjana Munshi and published by BoD – Books on Demand. This book was released on 2015-11-11 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book, Inherited Hemoglobin Disorders, describes the genetic defects of hemoglobins, disease complications, and therapeutic strategies. This book has two distinct sections. The first theme includes seven chapters devoted to the types of hemoglobinopathies, mutation spectrum, diagnostic methods, and disease complications, and the second theme includes three chapters focusing on various treatment strategies. The content of the chapters presented in the book is guided by the knowledge and experience of the contributing authors. This book serves as an important resource and review to the researchers in the field of hemoglobinopathies.
Author : Intsar S. Waked
Publisher : Nova Science Publishers
ISBN 13 : 9781634847049
Total Pages : 0 pages
Book Rating : 4.8/5 (47 download)
Download or read book Sickle Cell Anemia written by Intsar S. Waked and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sickle cell disease (SCD), an inherited hemolytic anemia, is associated with multiple acute and chronic complications such as painful vasoocclusive events, cerebral vasculopathy, priapism, and renal or lung disease. These complications are variable and unpredictable, and can be associated with significant morbidity and poor quality of life. This book covers several areas regarding pathology, diagnosis, complications, signs, symptoms and medical treatments. There are few studies in literature on the role of physiotherapy as a resource to prevent and treat locomotor system disorders, respiratory problems and painful crises in SCD individuals. This book highlights the role of physiotherapy in sickle cell anemia. A comprehensive and authoritative monograph, this book will be equally interesting to both established researchers and to graduate students interested in both genetics and the physical therapy field.
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309672988
Total Pages : 127 pages
Book Rating : 4.3/5 (96 download)
Download or read book Exploring Novel Clinical Trial Designs for Gene-Based Therapies written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-27 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the workshop discussed patient recruitment and selection for gene-based clinical trials, explored how the safety of new therapies is assessed, reviewed the challenges involving dose escalation, and spoke about ethical issues such as informed consent and the role of clinicians in recommending trials as options to their patients. The workshop also included discussions of topics related to gene therapies in the context of other available and potentially curative treatments, such as bone marrow transplantation for hemoglobinopathies. This publication summarizes the presentation and discussion of the workshop.
Author : Fernando Ferreira Costa
Publisher : Springer
ISBN 13 : 3319067133
Total Pages : 435 pages
Book Rating : 4.3/5 (19 download)
Download or read book Sickle Cell Anemia written by Fernando Ferreira Costa and published by Springer. This book was released on 2016-03-29 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although sickle cell anemia was the first molecular disease to be identified, its complex and fascinating pathophysiology is still not fully understood. A single mutation in the beta-globin gene incurs numerous molecular and cellular mechanisms that contribute to the plethora of symptoms associated with the disease. Our knowledge regarding sickle cell disease mechanisms, while still not complete, has broadened considerably over the last decades. Sickle Cell Anemia: From Basic Science to Clinical Practice aims to provide an update on our current understanding of the disease’s pathophysiology and use this information as a basis to discuss its manifestations in childhood and adulthood. Current therapies and prospects for the development of new approaches for the management of the disease are also covered.
Author : Dilip Singh Sisodia
Publisher : Medical Information Science Reference
ISBN 13 : 9781799821205
Total Pages : 300 pages
Book Rating : 4.8/5 (212 download)
Download or read book Advancement of Artificial Intelligence in Healthcare Engineering written by Dilip Singh Sisodia and published by Medical Information Science Reference. This book was released on 2020 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book explores the possible applications of machine learning, deep learning, soft computing, and evolutionary computing techniques in the design, implementation, and optimization of challenging healthcare engineering solutions"--
Author : Baba P.D. Inusa
Publisher : BoD – Books on Demand
ISBN 13 : 9535127667
Total Pages : 284 pages
Book Rating : 4.5/5 (351 download)
Download or read book Sickle Cell Disease written by Baba P.D. Inusa and published by BoD – Books on Demand. This book was released on 2016-11-10 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a wide range of clinically relevant topics and issues in sickle cell disease. This is written by experts in their own field offering a robust, engaging discussion about the presentations and mechanisms of actions in the multiple complications associated with sickle cell disease. This first of the series addresses pain, which is considered the hallmark of sickle cell presentation. It looks at the basic mechanism of pain in sickle cell disease. A more detailed review of precision medicine gives a clear well laid out presentation that is incisive and yet gives in-depth detail relevant to both the clinician and the researcher in the basic laboratory. The same pattern is shown in the discussion on respiratory, cardiac and neurological complications. The 14 chapters also include an overview of sickle cell disease especially in the paediatric age. The content is organized into well-designed broad sections on overview regarding diagnosis including point of care and the role of digital apps in patient management. A key aspect of the book is the opportunity it affords expert physicians to express well-reasoned opinions regarding complex issues in sickle cell disease. The readership would find that it provides a well-described, concise and immediate applicable answers to complex questions. This is highly recommended for scientists and clinicians alike.
Author : Martin H. Steinberg
Publisher : Cambridge University Press
ISBN 13 : 0521875196
Total Pages : 883 pages
Book Rating : 4.5/5 (218 download)
Download or read book Disorders of Hemoglobin written by Martin H. Steinberg and published by Cambridge University Press. This book was released on 2009-08-17 with total page 883 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the definitive reference on disorders of hemoglobin.
Author : Mark T. Gladwin
Publisher : McGraw Hill Professional
ISBN 13 : 1260458601
Total Pages : 715 pages
Book Rating : 4.2/5 (64 download)
Download or read book Sickle Cell Disease written by Mark T. Gladwin and published by McGraw Hill Professional. This book was released on 2021-01-05 with total page 715 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive, current sickle cell disease resource—for both clinicians and researchers A Doody's Core Title for 2023! The first and only resource of its kind, Sickle Cell Disease examines this blood disorder through both clinical and research lenses. More than 80 dedicated experts in the field present their combined clinical knowledge of basic mechanisms, screening, diagnosis, management, and treatment of myriad complex complications of a single base point mutation in the human genome. Case studies with “How I Treat” authoritative insights provide overviews of common and rare complications, and Key Facts offer at-a-glance high-yield information. Filled with clinical photos, illustrations, numerous original diagrams, and with free updates available online, this unmatched resource covers: Mechanisms of sickle cell disease Historic and current research approaches The latest work in gene therapy and editing Guidelines for patient care, diagnosis, unique cases, and therapies Rare and common complications, including domestic and internationally relevant topics Psychosocial and supportive care The newest standards of therapy and future treatment options in children and adults Cardiopulmonary complications
Author : Intsar S. Waked
Publisher :
ISBN 13 : 9781634848503
Total Pages : pages
Book Rating : 4.8/5 (485 download)
Download or read book Sickle Cell Anemia written by Intsar S. Waked and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : United States. Congress. Senate. Committee on Labor and Human Resources
Publisher :
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4.3/5 (91 download)
Download or read book Sickle Disease Research written by United States. Congress. Senate. Committee on Labor and Human Resources and published by . This book was released on 1994 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309669634
Total Pages : 523 pages
Book Rating : 4.3/5 (96 download)
Download or read book Addressing Sickle Cell Disease written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-12-22 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sickle cell disease (SCD) is a genetic condition that affects approximately 100,000 people in the United States and millions more globally. Individuals with SCD endure the psychological and physiological toll of repetitive pain as well as side effects from the pain treatments they undergo. Some adults with SCD report reluctance to use health care services, unless as a last resort, due to the racism and discrimination they face in the health care system. Additionally, many aspects of SCD are inadequately studied, understood, and addressed. Addressing Sickle Cell Disease examines the epidemiology, health outcomes, genetic implications, and societal factors associated with SCD and sickle cell trait (SCT). This report explores the current guidelines and best practices for the care of patients with SCD and recommends priorities for programs, policies, and research. It also discusses limitations and opportunities for developing national SCD patient registries and surveillance systems, barriers in the healthcare sector associated with SCD and SCT, and the role of patient advocacy and community engagement groups.
Author : Frank Leonard Johnson
Publisher :
ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.3/5 (91 download)
Download or read book Bone Marrow Transplantation in Children written by Frank Leonard Johnson and published by . This book was released on 1990 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Gabriel Gachelin
Publisher : John Libbey Eurotext
ISBN 13 : 9782742000630
Total Pages : 672 pages
Book Rating : 4.0/5 (6 download)
Download or read book Genes for Development, Cell Growth and Infectious Diseases written by Gabriel Gachelin and published by John Libbey Eurotext. This book was released on 1995 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work which was published to mark the tenth anniversary of the collaboration between the Institut Pasteur and the Riken Institute in Japan, covers a number of research fields in which both laboratories are active: precocious development in mice and the effect on them of disactivating genes, nuclear oncogenes and their role in controlling cell division, and the molecular bases of bacterial and viral infections. There are also chapters dealing with specific aspects of immune recognition, the genetics of sexual determination in humans and a new technique for studying the human genome. This book is intended for researchers and physicians in the fields of immunology, genetics, bacteriology/virology, cancerology, developmental biology, cellular biology and neurobiology.
