New Approaches And Insights Into The Gene Expression Of Toxoplasma Gondii

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Toxoplasma Gondii

Author : Louis M. Weiss
Publisher : Academic Press
ISBN 13 : 0123965365
Total Pages : 1109 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Toxoplasma Gondii by : Louis M. Weiss

Download or read book Toxoplasma Gondii written by Louis M. Weiss and published by Academic Press. This book was released on 2013-08-10 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. - Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen - Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis - Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists

Toxoplasmosis of Animals and Humans

Author : J. P. Dubey
Publisher : CRC Press
ISBN 13 : 1420092375
Total Pages : 336 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Toxoplasmosis of Animals and Humans by : J. P. Dubey

Download or read book Toxoplasmosis of Animals and Humans written by J. P. Dubey and published by CRC Press. This book was released on 2016-04-19 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publi

Biodefense in the Age of Synthetic Biology

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309465184
Total Pages : 189 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Biodefense in the Age of Synthetic Biology by : National Academies of Sciences, Engineering, and Medicine

Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Disease Control Priorities, Third Edition (Volume 6)

Author : King K. Holmes
Publisher : World Bank Publications
ISBN 13 : 1464805253
Total Pages : 1027 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Disease Control Priorities, Third Edition (Volume 6) by : King K. Holmes

Download or read book Disease Control Priorities, Third Edition (Volume 6) written by King K. Holmes and published by World Bank Publications. This book was released on 2017-11-06 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

The Neurobiological Basis of Suicide

Author : Yogesh Dwivedi
Publisher : CRC Press
ISBN 13 : 143983881X
Total Pages : 485 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Neurobiological Basis of Suicide by : Yogesh Dwivedi

Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Intracellular Parasitism

Author : James W. Moulder
Publisher : CRC Press
ISBN 13 : 1000141667
Total Pages : 296 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Intracellular Parasitism by : James W. Moulder

Download or read book Intracellular Parasitism written by James W. Moulder and published by CRC Press. This book was released on 2020-10-28 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication is a collection of essays on the biology of intracellular parasitisms where both bacterial and protozoan parasites are discussed. The juxtaposition of authors representing fields of research emphasizes the many common problems facing intracellular parasites and the hosts that harbor them. In addition, numerous illustrations of how different parasites and host attempt to solve these problems in different ways are provided. The book includes one or more chapters on Bdellovibrio, Chlamydia, Rickettsia, Coxiella, Legionella, Shigellae, Mycobacterium, Microsporidium, Plasmodium, and Toxoplasma. The authors frequently speculate and generalize on the subject matter discussed.

Genes and Evolution

Author :
Publisher : Academic Press
ISBN 13 : 0124172016
Total Pages : 434 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Genes and Evolution by :

Download or read book Genes and Evolution written by and published by Academic Press. This book was released on 2016-06-06 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes and Evolution, the latest volume in the Current Topics in Developmental Biology series, covers genes and evolution, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes, and epithelial tissue. - Covers the area of genes and evolution - Contains invaluable contributions from an international board of authors - Provides a comprehensive set of reviews covering such topics as genes and plant domestication, gene networks, phenotypic loss in vertebrates, reproducible evolutionary changes and epithelial tissue

Veterinary Parasitology

Author : Hany Elsheikha
Publisher : CRC Press
ISBN 13 : 1840766468
Total Pages : 256 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Veterinary Parasitology by : Hany Elsheikha

Download or read book Veterinary Parasitology written by Hany Elsheikha and published by CRC Press. This book was released on 2013-06-04 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinically oriented new volume in the Self-Assessment Colour Review series brings together a wide variety of cases and clinical situations which relate to diseases caused by parasitic agents primarily in small animals and domestic livestock. It also includes some cases involving some wild and exotic animals.The cases are presented randomly, an

Neuroparasitology and Tropical Neurology

Author : Oscar H. Del Brutto
Publisher : Elsevier Inc. Chapters
ISBN 13 : 012807969X
Total Pages : 38 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuroparasitology and Tropical Neurology by : Oscar H. Del Brutto

Download or read book Neuroparasitology and Tropical Neurology written by Oscar H. Del Brutto and published by Elsevier Inc. Chapters. This book was released on 2013-07-03 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.

Neosporosis in Animals

Author : J.P. Dubey
Publisher : CRC Press
ISBN 13 : 1351648608
Total Pages : 512 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Neosporosis in Animals by : J.P. Dubey

Download or read book Neosporosis in Animals written by J.P. Dubey and published by CRC Press. This book was released on 2017-07-12 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key features: Written by the scientist who named this parasite and was the first to set up proper diagnostic techniques Serves as the first ever book to provide information on the parasite structure, biology, pathogenesis, clinical signs, epidemiology, prevention, and control of neosporosis Covers both approaches toward preventing & controlling this disease: Developing an efficacious vaccine and sound cattle management practices Contains a wealth of illustrations, including many of the author's original photographs of the parasite Provides basic information on immunologic and molecular aspects of the disease Abortion is a worldwide problem in the livestock industry accounting for annual economic losses of billions of dollars, and N. caninum is a major cause of it. Neosporosis is a newly recognized disease of animals. Until 1988 it was misdiagnosed as toxoplasmosis. Considerable progress in understanding the biology of neosporosis has been made in the last 30 years, resulting in more than 2,000 scientific publications. The economic importance of abortion in cattle, and the availability of knowledge, reagents, and technology used to study toxoplasmosis, have contributed to the rapid progress in understanding the biology of neosporosis. Written by pioneers in this field, Neosporosis in Animals presents a comprehensive summary of the biology of neosporosis, starting with chapter 1 on the historical background of the discovery of the disease. Subsequent chapters deal with general aspects of the biology of N. caninum (chapter 2), techniques (chapter 3), and the disease caused by this parasite in cattle (chapter 4), dogs (chapter 5), and all other animals including sheep, pigs, primates and humans (chapters 6-18). This book provides, for the first time in a single authoritative source, a complete account of the structure, biology, clinical disease, diagnosis, epidemiology, treatment, attempts at immunoprophylaxis, and control in all hosts. There are 175 illustrations and tables devoted to the life cycle, structure of parasitic stages, and lesions. More than 2100 references are cited, allowing the reader to locate additional information on specific topics in an efficient way. This book will be useful to a broad range of researchers in biology and veterinarians.

Immunization Against East Coast Fever: Isolation and Characterization of Theileria Parva Stocks From Unguja and Pemba for Use in Infection and Treatment

Download Immunization Against East Coast Fever: Isolation and Characterization of Theileria Parva Stocks From Unguja and Pemba for Use in Infection and Treatment PDF Online Free

Author : Subhash P. Morzaria
Publisher : ILRI (aka ILCA and ILRAD)
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4./5 ( download)

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Book Synopsis Immunization Against East Coast Fever: Isolation and Characterization of Theileria Parva Stocks From Unguja and Pemba for Use in Infection and Treatment by : Subhash P. Morzaria

Download or read book Immunization Against East Coast Fever: Isolation and Characterization of Theileria Parva Stocks From Unguja and Pemba for Use in Infection and Treatment written by Subhash P. Morzaria and published by ILRI (aka ILCA and ILRAD). This book was released on 1986-01-01 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Apicomplexan Parasites

Author : Katja Becker
Publisher : John Wiley & Sons
ISBN 13 : 3527633901
Total Pages : 548 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Apicomplexan Parasites by : Katja Becker

Download or read book Apicomplexan Parasites written by Katja Becker and published by John Wiley & Sons. This book was released on 2011-01-19 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is the first dealing with the discovery of drugs directed against apicomplexan parasites. Amongst others, this group of endoparasites includes the causative agents of Malaria, Toxoplasmosis, and Babesiosis, the latter occurring mainly in animals. Written by renowned scientific experts from academia and industry, the book focuses on currentdrug development approaches for all apicomplexan diseases making it appealing to a large audience, ranging from research labs in academia to the human and veterinarian pharmaceutical industry. This work is the second volume of the new book series 'Drug Discovery in Infectious Diseases', edited by Prof. Dr Paul M. Selzer.

Toxoplasma gondii

Author : Uwe Gross
Publisher : Springer Science & Business Media
ISBN 13 : 3642510140
Total Pages : 268 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Toxoplasma gondii by : Uwe Gross

Download or read book Toxoplasma gondii written by Uwe Gross and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: For years, toxoplasmosis has been known as disease mostly affecting newborns. Since immunocompromised patients (AIDS) present a high risk of reactivation of chronic toxoplasmosis this parasitic disease has gained increasing interest. Besides presenting clinical and therapeutical concepts, this volume provides current knowledge about genetics and immunology of T. gondii and the interaction with its 'host'. Since in vivo and in vitro models of toxoplasmosis exist, and genetic manipulation has become possible, this protozoan parasite has recently been accepted as a model for understanding the pathogenesis and persistance of other intracellular parasites. The articles of the book compromise both reviewing current concepts and reporting on yet unpublished results of leading scientists in this field.

Microbial Ecology in States of Health and Disease

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309290651
Total Pages : 436 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Microbial Ecology in States of Health and Disease by : Institute of Medicine

Download or read book Microbial Ecology in States of Health and Disease written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-18 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction - across the spectrum of hosts, microbes, and environmental niches - that influence the formation, function, and stability of host-associated microbial communities. Microbial Ecology in States of Health and Disease is the summary of a workshop convened by the Institute of Medicine's Forum on Microbial Threats in March 2013 to explore the scientific and therapeutic implications of microbial ecology in states of health and disease. Participants explored host-microbe interactions in humans, animals, and plants; emerging insights into how microbes may influence the development and maintenance of states of health and disease; the effects of environmental change(s) on the formation, function, and stability of microbial communities; and research challenges and opportunities for this emerging field of inquiry.

The Vaccine Book

Author : Barry R. Bloom
Publisher : Academic Press
ISBN 13 : 012805400X
Total Pages : 666 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Vaccine Book by : Barry R. Bloom

Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk. - Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines - Gives new ideas about future vaccines and concepts - Introduces new vaccines and concepts - Gives ideas about challenges facing public and private industrial investors in the vaccine area - Discusses the problem of declining immunization rates and vaccine hesitancy

Toxoplasmosis of Animals and Humans, Second Edition

Author : J. P. Dubey
Publisher : CRC Press
ISBN 13 : 9780849346187
Total Pages : 232 pages
Book Rating : 4.3/5 (461 download)

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Book Synopsis Toxoplasmosis of Animals and Humans, Second Edition by : J. P. Dubey

Download or read book Toxoplasmosis of Animals and Humans, Second Edition written by J. P. Dubey and published by CRC Press. This book was released on 1988-08-31 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complete information on T. gondii infections in animals and man is summarized and analyzed in this thorough reference text. Critical in-formation on its economic impact and its effect on production of animals whose flesh is used for food is featured. The clinical and subclinical infections in all major species of livestock are pre-sented. For each animal species, worldwide serological prevalences are tabulated with T. gondii antibody titers, followed by an experi-mental section. Worldwide prevalences of T. gondii infections in mankind is summarized, highlighting epidemiology, symptom diag-nosis, treatment, and prevention. Past research is summarized and areas of future investigations are suggested. This book is highly useful to veterinarians, physicians, biologists, and researchers.

Toxoplasmosis

Author : David H. M. Joynson
Publisher : Cambridge University Press
ISBN 13 : 9780521019422
Total Pages : 412 pages
Book Rating : 4.0/5 (194 download)

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Book Synopsis Toxoplasmosis by : David H. M. Joynson

Download or read book Toxoplasmosis written by David H. M. Joynson and published by Cambridge University Press. This book was released on 2005-09-08 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative and comprehensive account looks at the reemergence of toxoplasmosis as a significant and potentially fatal infection. A team of acknowledged international experts review the latest diagnostic techniques, and the management of infection in pregnant women, neonates, the eye, transplant and other immunosuppressed patients, including AIDS patients. The contentious issue of the role of screening during pregnancy and in the newborn is covered in depth. The introductory chapters on biology, immunology, and epidemiology of the infection provide essential background to understanding the clinical disease. The full range of treatment strategies are presented in an easily accessible form.