Neuroplastic Changes In Addiction

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Neuroplastic changes in addiction

Author : Ildikó Rácz
Publisher : Frontiers E-books
ISBN 13 : 288919213X
Total Pages : 108 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Neuroplastic changes in addiction by : Ildikó Rácz

Download or read book Neuroplastic changes in addiction written by Ildikó Rácz and published by Frontiers E-books. This book was released on 2014-05-05 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addiction is a chronic relapsing disorder, which comprises impulsive and compulsive elements. Chronic drug consumption leads to long-term neuroadaptive changes in the brain thus result in an addictive state. However, development of addiction is a complex interaction between genetic, epigenetic and environmental factors. The resulting cellular and molecular changes mediate the transition from controlled drug use to the loss of control over drug-taking and drug-seeking. The human association studies helped us to identify some important genetic factors responsible for the susceptibility to addiction. However, social, environmental circumstances highly influence the development of addiction. Using animal models helps us to examine the underlying neuronal/molecular processes under standardised conditions. The aim of this Research Topic is to summarize our knowledge about the neuroplastic changes, which contribute to the maintenance of drug taking. Data presented in this Research Topic should also provide evidences how acute and long-term neuronal changes during withdrawal result in relapse. How different neuromodulators like endocannabinoids and endogenous opioids contribute to molecular mechanisms that mediate the transition from the controlled, occasional drug consumption to the uncontrolled, escalating drug use and seeking.

Neural Mechanisms of Addiction

Author : Mary Torregrossa
Publisher : Academic Press
ISBN 13 : 0128123311
Total Pages : 306 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Neural Mechanisms of Addiction by : Mary Torregrossa

Download or read book Neural Mechanisms of Addiction written by Mary Torregrossa and published by Academic Press. This book was released on 2018-08-24 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research. Transcends multiple neural, neurochemical and behavioral domains Summarizes advances in the field of addiction research since the advent of optogenetics Discusses the most current, leading theories of addiction, including molecular mechanisms and dopamine mechanisms

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 412 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

The Biology of Desire

Author : Marc Lewis
Publisher : PublicAffairs
ISBN 13 : 1610394380
Total Pages : 256 pages
Book Rating : 4.6/5 (13 download)

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Book Synopsis The Biology of Desire by : Marc Lewis

Download or read book The Biology of Desire written by Marc Lewis and published by PublicAffairs. This book was released on 2015-07-14 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist explains why the "disease model" of addiction is wrong and illuminates the path to recovery. The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease, and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it's supposed to do-seek pleasure and relief-in a world that's not cooperating. As a result, most treatment based on the disease model fails. Lewis shows how treatment can be retooled to achieve lasting recovery. This is enlightening and optimistic reading for anyone who has wrestled with addiction either personally or professionally.

Facing Addiction in America

Author : Office of the Surgeon General
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781974580620
Total Pages : 420 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis Facing Addiction in America by : Office of the Surgeon General

Download or read book Facing Addiction in America written by Office of the Surgeon General and published by Createspace Independent Publishing Platform. This book was released on 2017-08-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.

Neurocircuitry of Addiction

Author : Nicholas W. Gilpin
Publisher : Academic Press
ISBN 13 : 0128234547
Total Pages : 560 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Neurocircuitry of Addiction by : Nicholas W. Gilpin

Download or read book Neurocircuitry of Addiction written by Nicholas W. Gilpin and published by Academic Press. This book was released on 2022-11-29 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: People use drugs for many different reasons, including the pursuit of "high," social factors and self-medication of other conditions. Many millions of people are addicted to at least one substance, and the cost of addiction is immense, at both the individual and societal levels. Neurocircuitry of Addiction is the first book of its kind, with a focus on addiction neuroscience from a neural circuit perspective. This book begins with a primer on circuit-based neuroscience that equips the reader with an understanding of the applications described throughout the book. Each subsequent chapter positions a different brain region at the "center" of addiction neurocircuitry and goes on to describe the anatomical connectivity of that brain region, how those circuits are affected by drug exposure, and the role of those circuits in controlling addiction-related behaviors. All chapters of this book are written by content experts for a target audience that has some basic neuroscience background, but no prior in-depth knowledge regarding the neurocircuitry of addiction. Reviews the circuit-based tools that are used by scientists to investigate neural circuit function Describes how acute and chronic alcohol and drug exposure affect neural circuit function Describes the state of the science regarding the role of specific neural circuis in drug addiction Chapters include data from both human neuroscience and animal models

Never Enough

Author : Judith Grisel
Publisher : Anchor
ISBN 13 : 0525434909
Total Pages : 257 pages
Book Rating : 4.5/5 (254 download)

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Book Synopsis Never Enough by : Judith Grisel

Download or read book Never Enough written by Judith Grisel and published by Anchor. This book was released on 2020-01-14 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW YORK TIMES BESTSELLER • From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

Beyond Addiction

Author : Jeffrey Foote
Publisher : Simon and Schuster
ISBN 13 : 1476709475
Total Pages : 336 pages
Book Rating : 4.4/5 (767 download)

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Book Synopsis Beyond Addiction by : Jeffrey Foote

Download or read book Beyond Addiction written by Jeffrey Foote and published by Simon and Schuster. This book was released on 2014-02-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most innovative leaders in progressive addiction treatment in the US offer a groundbreaking, science-based guide to helping loved ones overcome addiction problems and compulsive behaviors. The most innovative leaders in progressive addiction treatment in the US offer a groundbreaking, science-based guide to helping loved ones overcome addiction problems and compulsive behaviors. Beyond Addiction eschews the theatrics of interventions and tough love to show family and friends how they can use kindness, positive reinforcement, and motivational and behavioral strategies to help their loved ones change. Drawing on forty collective years of research and decades of clinical experience, the authors present the best practical advice science has to offer. Delivered with warmth, optimism, and humor, Beyond Addiction defines a new, empowered role for friends and family and a paradigm shift for the field. Learn how to tap the transformative power of relationships for positive change, guided by exercises and examples. Practice what really works in therapy and in everyday life, and discover many different treatment options along with tips for navigating the system. And have hope: this guide is designed not only to help someone change, but to help someone want to change.

Neuroplasticity: Your Brain's Superpower

Author : Philippe Douyon MD
Publisher : Izzard Ink
ISBN 13 : 1642281018
Total Pages : 85 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Neuroplasticity: Your Brain's Superpower by : Philippe Douyon MD

Download or read book Neuroplasticity: Your Brain's Superpower written by Philippe Douyon MD and published by Izzard Ink. This book was released on 2019-04-23 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: We live in a time in which more than 100 million Americans suffer from a neurological illness. Not only is that number expected to rise and the annual cost to care for people with neurological disorders expected to surpass 1 trillion dollars, but the impact of these illnesses on our lives is unlike any other. Neurological disorders affect every fiber of our being. They cause physical, psychological, emotional, and cognitive impairments. They rob us of our lives and families in a way that diseases of other organs can’t. Oftentimes it seems that we are helpless to do anything about it. But, what if that wasn’t true? Neuroplasticity: Your Brain’s Superpower empowers us to have a different relationship with our brains. Instead of just succumbing to whatever potential dysfunction, degeneration, or disease that may impact our nervous system, in this book we explore the ways in which we can give our brains exactly what they need to adapt, heal, and thrive. Neuroplasticity: Your Brain’s Superpower takes us on a journey through things that influence the evolution of our brains, including various diseases. Not only do we learn about these illnesses, but also about the potential healing that can take place after the injury. This book expands the conversation about brain health so that we can include the principles of neuroplasticity to help us take control of our neurological destinies.

Cognition and Addiction

Author : Antonio Verdejo García
Publisher : Academic Press
ISBN 13 : 0128152990
Total Pages : 442 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Cognition and Addiction by : Antonio Verdejo García

Download or read book Cognition and Addiction written by Antonio Verdejo García and published by Academic Press. This book was released on 2019-09-29 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cognition and Addiction: A Researcher’s Guide from Mechanisms Towards Interventions provides researchers with a guide to recent cognitive neuroscience advances in addiction theory, phenotyping, treatments and new vistas, including both substance and behavioral addictions. This book focuses on “what to know and “how to apply information, prioritizing novel principles and delineating cutting-edge assessment, phenotyping and treatment tools. Written by world renowned researcher Antonio Verdejo-Garcia, this resource will become a go-to guide for researchers in the field of cognitive neuroscience and addiction. Examines cognitive neuroscience advances in addiction theory, including both substance and behavioral addictions Discusses primary principles of cutting-edge assessment, phenotyping and treatment tools Includes detailed chapters on neuro-epidemiology and genetic imaging

Behavioral Neuroscience of Drug Addiction

Author : David W. Self
Publisher : Springer Science & Business Media
ISBN 13 : 3642030017
Total Pages : 392 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Behavioral Neuroscience of Drug Addiction by : David W. Self

Download or read book Behavioral Neuroscience of Drug Addiction written by David W. Self and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.

Neurobiology of Addiction

Author : George F. Koob
Publisher : Elsevier
ISBN 13 : 0080497373
Total Pages : 503 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Neurobiology of Addiction by : George F. Koob

Download or read book Neurobiology of Addiction written by George F. Koob and published by Elsevier. This book was released on 2005-11-11 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

The Brain That Changes Itself

Author : Norman Doidge, M.D.
Publisher : Penguin
ISBN 13 : 1101147113
Total Pages : 447 pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis The Brain That Changes Itself by : Norman Doidge, M.D.

Download or read book The Brain That Changes Itself written by Norman Doidge, M.D. and published by Penguin. This book was released on 2007-03-15 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Fascinating. Doidge’s book is a remarkable and hopeful portrait of the endless adaptability of the human brain.”—Oliver Sacks, MD, author of The Man Who Mistook His Wife for a Hat What is neuroplasticity? Is it possible to change your brain? Norman Doidge’s inspiring guide to the new brain science explains all of this and more An astonishing new science called neuroplasticity is overthrowing the centuries-old notion that the human brain is immutable, and proving that it is, in fact, possible to change your brain. Psychoanalyst, Norman Doidge, M.D., traveled the country to meet both the brilliant scientists championing neuroplasticity, its healing powers, and the people whose lives they’ve transformed—people whose mental limitations, brain damage or brain trauma were seen as unalterable. We see a woman born with half a brain that rewired itself to work as a whole, blind people who learn to see, learning disorders cured, IQs raised, aging brains rejuvenated, stroke patients learning to speak, children with cerebral palsy learning to move with more grace, depression and anxiety disorders successfully treated, and lifelong character traits changed. Using these marvelous stories to probe mysteries of the body, emotion, love, sex, culture, and education, Dr. Doidge has written an immensely moving, inspiring book that will permanently alter the way we look at our brains, human nature, and human potential.

Psychoneuroplasticity Protocols for Addictions

Author : Frank Lawlis
Publisher : Rowman & Littlefield
ISBN 13 : 1442241993
Total Pages : 205 pages
Book Rating : 4.4/5 (422 download)

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Book Synopsis Psychoneuroplasticity Protocols for Addictions by : Frank Lawlis

Download or read book Psychoneuroplasticity Protocols for Addictions written by Frank Lawlis and published by Rowman & Littlefield. This book was released on 2015-03-10 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: PsychoNeuroPlasticity Protocols for Addictions: A Clinical Companion for the Big Book is a book that represents a tipping point in the translation of addiction science into practical, real-world applications for practitioners. It translates brain research into patient deliverables by explaining how to use the brain to fight addiction and improve recovery outcomes. It does so while embracing the long-standing recovery culture that has been the only source of hope for addicts and alcoholics in the past fifty years. The contents of the book reveal the transformational aspects of recovery along with the scientific principles of what Dr. Lawlis has coined as “PsychoNeuroPlasticity,” along with many of the barriers to transformation. More specifically it covers brain patterns that relate to depression, anxiety, OCD, mood and even brain development issues noted in premature development of adjustment in young addicts. The approaches are not singular in nature, but cover a wide range of effective modes of treatment, including diet, exercise, meditation, and biofeedback. The reader and treatment specialist will be re-energized by witnessing the changes in patient care, staff training, and outcomes. Digging deeper, however, this book is about hope—hope that the work of two decades of brain science will finally reach those who need it most; hope that we finally have a tool that will give us a true advantage in the war on addiction; and hope that lives lost to this disease every year will someday be stymied.

Drugs, Brains, and Behavior

Author :
Publisher :
ISBN 13 :
Total Pages : 76 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Drugs, Brains, and Behavior by :

Download or read book Drugs, Brains, and Behavior written by and published by . This book was released on 2007 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic Communities for the Treatment of Drug Users

Author : Barbara Rawlings
Publisher : Jessica Kingsley Pub
ISBN 13 : 9781853028175
Total Pages : 272 pages
Book Rating : 4.0/5 (281 download)

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Book Synopsis Therapeutic Communities for the Treatment of Drug Users by : Barbara Rawlings

Download or read book Therapeutic Communities for the Treatment of Drug Users written by Barbara Rawlings and published by Jessica Kingsley Pub. This book was released on 2001 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by academics and practitioners from around the world, this is a comprehensive overview of the development of therapeutic communities and their benefits for treating drug users. Contributors describe how the model operates in the community, and how it has been modified to fit different settings, types of client and referral requirements.

Cognitive Plasticity in Neurologic Disorders

Author : Joseph I. Tracy
Publisher : Oxford University Press, USA
ISBN 13 : 0199965242
Total Pages : 433 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Cognitive Plasticity in Neurologic Disorders by : Joseph I. Tracy

Download or read book Cognitive Plasticity in Neurologic Disorders written by Joseph I. Tracy and published by Oxford University Press, USA. This book was released on 2014-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.