Neuronal Correlates Of The Bold Signal During Visual Stimulations

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Neuronal Correlates of the BOLD Signal During Visual Stimulations

Author : Qingqing Zhang
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Neuronal Correlates of the BOLD Signal During Visual Stimulations by : Qingqing Zhang

Download or read book Neuronal Correlates of the BOLD Signal During Visual Stimulations written by Qingqing Zhang and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The blood oxygenation-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) has been widely used to study brain functions with the assumption that it provides an indirect measurement of neuronal-related events. Despite its popularity, there are still important unresolved issues in BOLD-fMRI. First, it is well known that BOLD responses exhibit considerable variations to identical stimulation presentations. To quantitatively characterize this variability, the BOLD signal has been modeled as a linear summation of a stimulation-relevant and a stimulation-irrelevant (i.e., ongoing) component. However, a systematic investigation of the spatiotemporal features of the brain-wide ongoing BOLD component and how these features affect the trial-to-trial variability of BOLD responses are still lacking. To explore these questions, we collected the brain-wide BOLD response with fMRI and local neuronal response with fiber photometry during sustained light ON-OFF stimulations in unanesthetized rats. Our data for the first time revealed the BOLD responsive features to the visual stimulation onset and offset in unanesthetized rodents. Importantly, the cross-region BOLD responses were highly correlated at zero time lag. A linear model with the ongoing response estimated from the rest of the brain explained a large amount of the variance in the measured BOLD responses of visual regions, and removing this ongoing response improved the detection sensitivity of fMRI. Furthermore, in a significant portion of trials, negative BOLD ongoing activity was brain-wide and dominated over the stimulation-induced response, while populational neuronal firing measured by calcium-based fiber photometry remained unchanged. The second unresolved issue in BOLD-fMRI is that when the BOLD response is more complex than a stimulation-related monophasic impulse function, how BOLD signals in different phases relate to neural (or non-neural) signals has remained elusive. With the visual stimulation paradigms we developed, we observed reproducible multi-phase BOLD responses. Results from electrophysiological recordings in unanesthetized rats experiencing the same paradigms as in the fMRI experiments showed that the temporal evolution of the muti-unit activity (MUA) band (300 -- 3000 Hz) power, rather than the gamma-band (30 -- 100 Hz) power, highly resembled the BOLD dynamics. This result suggests that when populational neuronal spiking is dissociated from the gamma LFP, post-stimulus phases of the BOLD response can be better explained by the MUA signal.

Introduction to Functional Magnetic Resonance Imaging

Author : Richard B. Buxton
Publisher : Cambridge University Press
ISBN 13 : 1139481304
Total Pages : 479 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Introduction to Functional Magnetic Resonance Imaging by : Richard B. Buxton

Download or read book Introduction to Functional Magnetic Resonance Imaging written by Richard B. Buxton and published by Cambridge University Press. This book was released on 2009-08-27 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Magnetic Resonance Imaging (fMRI) has become a standard tool for mapping the working brain's activation patterns, both in health and in disease. It is an interdisciplinary field and crosses the borders of neuroscience, psychology, psychiatry, radiology, mathematics, physics and engineering. Developments in techniques, procedures and our understanding of this field are expanding rapidly. In this second edition of Introduction to Functional Magnetic Resonance Imaging, Richard Buxton – a leading authority on fMRI – provides an invaluable guide to how fMRI works, from introducing the basic ideas and principles to the underlying physics and physiology. He covers the relationship between fMRI and other imaging techniques and includes a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced radiographer, and the clinician or researcher with no previous knowledge of the technology.

The Neural Bases of Multisensory Processes

Author : Micah M. Murray
Publisher : CRC Press
ISBN 13 : 1439812179
Total Pages : 800 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Neural Bases of Multisensory Processes by : Micah M. Murray

Download or read book The Neural Bases of Multisensory Processes written by Micah M. Murray and published by CRC Press. This book was released on 2011-08-25 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has become accepted in the neuroscience community that perception and performance are quintessentially multisensory by nature. Using the full palette of modern brain imaging and neuroscience methods, The Neural Bases of Multisensory Processes details current understanding in the neural bases for these phenomena as studied across species, stages of development, and clinical statuses. Organized thematically into nine sub-sections, the book is a collection of contributions by leading scientists in the field. Chapters build generally from basic to applied, allowing readers to ascertain how fundamental science informs the clinical and applied sciences. Topics discussed include: Anatomy, essential for understanding the neural substrates of multisensory processing Neurophysiological bases and how multisensory stimuli can dramatically change the encoding processes for sensory information Combinatorial principles and modeling, focusing on efforts to gain a better mechanistic handle on multisensory operations and their network dynamics Development and plasticity Clinical manifestations and how perception and action are affected by altered sensory experience Attention and spatial representations The last sections of the book focus on naturalistic multisensory processes in three separate contexts: motion signals, multisensory contributions to the perception and generation of communication signals, and how the perception of flavor is generated. The text provides a solid introduction for newcomers and a strong overview of the current state of the field for experts.

The Superficial Veins of the Human Brain

Author : Henri M. Duvernoy
Publisher : Springer
ISBN 13 :
Total Pages : 128 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Superficial Veins of the Human Brain by : Henri M. Duvernoy

Download or read book The Superficial Veins of the Human Brain written by Henri M. Duvernoy and published by Springer. This book was released on 1975 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Simultaneous EEG and FMRI

Author : Markus Ullsperger
Publisher : Oxford University Press
ISBN 13 : 0195372735
Total Pages : 332 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Simultaneous EEG and FMRI by : Markus Ullsperger

Download or read book Simultaneous EEG and FMRI written by Markus Ullsperger and published by Oxford University Press. This book was released on 2010-05-28 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major challenges in science is to study and understand the human brain. Numerous methods examining different aspects of brain functions have been developed and employed. To study systemic interactions brain networks in vivo, non-invasive methods such as electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have been used with great success. However, each of these methods can map only certain, quite selective aspects of brain function while missing others; and the inferences on neuronal processes and information flow are often rather indirect. To overcome these shortcomings of single methods, researchers have attempted to combine methods in order to make optimal use of their advantages while compensating their disadvantages. Hence, it is not surprising that soon after the introduction of fMRI as a neuroimaging method the possibilities of combinations with EEG have been explored.This book is intended to aid researchers who plan to set up a simultaneous EEG-fMRI laboratory and those who are interested in integrating electrophysiological and hemodynamic data. As will be obvious from the different chapters, this is a dynamically developing field in which several approaches are being tested, validated and compared. Currently, there is no one best solution for all problems available, but many promising techniques are emerging. This book shall give a comprehensive overview of these techniques. In addition, it points to open questions and directions for future research.

A Cognitive Theory of Consciousness

Author : Bernard J. Baars
Publisher : Cambridge University Press
ISBN 13 : 9780521427432
Total Pages : 454 pages
Book Rating : 4.4/5 (274 download)

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Book Synopsis A Cognitive Theory of Consciousness by : Bernard J. Baars

Download or read book A Cognitive Theory of Consciousness written by Bernard J. Baars and published by Cambridge University Press. This book was released on 1993-07-30 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bernard Baars suggests a way to specify empirical constraints on a theory of consciousness by contrasting well-established conscious phenomena with comparable unconscious ones, such as stimulus representations known to be preperceptual, unattended or habituated. By adducing data to show that consciousness is associated with a kind of workplace in the nervous system, Baars helps clarify the problem.

Neuroimaging of Sleep and Sleep Disorders

Author : Eric Nofzinger
Publisher : Cambridge University Press
ISBN 13 : 1107018633
Total Pages : 445 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Neuroimaging of Sleep and Sleep Disorders by : Eric Nofzinger

Download or read book Neuroimaging of Sleep and Sleep Disorders written by Eric Nofzinger and published by Cambridge University Press. This book was released on 2013-03-07 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.

The Hippocampus Book

Author : Per Andersen
Publisher : Oxford University Press
ISBN 13 : 9780195100273
Total Pages : 892 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis The Hippocampus Book by : Per Andersen

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Progress in Brain Research

Author : J. P. Schadé
Publisher :
ISBN 13 : 9780444409522
Total Pages : 438 pages
Book Rating : 4.4/5 (95 download)

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Book Synopsis Progress in Brain Research by : J. P. Schadé

Download or read book Progress in Brain Research written by J. P. Schadé and published by . This book was released on 1963 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Dynamic Brain

Author : Mingzhou Ding
Publisher : Oxford University Press, USA
ISBN 13 : 0195393791
Total Pages : 393 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis The Dynamic Brain by : Mingzhou Ding

Download or read book The Dynamic Brain written by Mingzhou Ding and published by Oxford University Press, USA. This book was released on 2011 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical, experimental and clinical perspectives. Readership: Graduate students, postdocs and research scientists in Neuroscience.

Neuroscience in the 21st Century

Author : Donald W. Pfaff
Publisher : Springer
ISBN 13 : 9781493934737
Total Pages : 0 pages
Book Rating : 4.9/5 (347 download)

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Book Synopsis Neuroscience in the 21st Century by : Donald W. Pfaff

Download or read book Neuroscience in the 21st Century written by Donald W. Pfaff and published by Springer. This book was released on 2016-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.

The Oxford Handbook of Voice Perception

Author : Sascha ühholz
Publisher : Oxford University Press, USA
ISBN 13 : 0198743181
Total Pages : 977 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis The Oxford Handbook of Voice Perception by : Sascha ühholz

Download or read book The Oxford Handbook of Voice Perception written by Sascha ühholz and published by Oxford University Press, USA. This book was released on 2019-01-29 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: Speech perception has been the focus of innumerable studies over the past decades. While our abilities to recognize individuals by their voice state plays a central role in our everyday social interactions, limited scientific attention has been devoted to the perceptual and cerebral mechanisms underlying nonverbal information processing in voices. The Oxford Handbook of Voice Perception takes a comprehensive look at this emerging field and presents a selection of current research in voice perception. The forty chapters summarise the most exciting research from across several disciplines covering acoustical, clinical, evolutionary, cognitive, and computational perspectives. In particular, this handbook offers an invaluable window into the development and evolution of the 'vocal brain', and considers in detail the voice processing abilities of non-human animals or human infants. By providing a full and unique perspective on the recent developments in this burgeoning area of study, this text is an important and interdisciplinary resource for students, researchers, and scientific journalists interested in voice perception.

Functional MRI

Author : Scott H. Faro
Publisher : Springer Science & Business Media
ISBN 13 : 0387346651
Total Pages : 543 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Functional MRI by : Scott H. Faro

Download or read book Functional MRI written by Scott H. Faro and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional magnetic resonance imaging (fMRI) measures quick, tiny metabolic changes that take place in the brain, providing the most sensitive method currently available for identifying, investigating, and monitoring brain tumors, stroke, and chronic disorders of the nervous system like multiple sclerosis, and brain abnormalities related to dementia or seizures. This overview explores experimental research design, outlines challenges and limitations of fMRI, provides a detailed neuroanatomic atlas, and describes clinical applications of fMRI in cognitive, sensory, motor, and pharmacological cases, translating research into clinical application.

Brain Repair After Stroke

Author : Steven C. Cramer
Publisher : Cambridge University Press
ISBN 13 : 1139490656
Total Pages : 307 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Brain Repair After Stroke by : Steven C. Cramer

Download or read book Brain Repair After Stroke written by Steven C. Cramer and published by Cambridge University Press. This book was released on 2010-10-28 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.

Single Neuron Studies of the Human Brain

Author : Itzhak Fried
Publisher : MIT Press
ISBN 13 : 0262324008
Total Pages : 391 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Single Neuron Studies of the Human Brain by : Itzhak Fried

Download or read book Single Neuron Studies of the Human Brain written by Itzhak Fried and published by MIT Press. This book was released on 2014-06-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundational studies of the activities of spiking neurons in the awake and behaving human brain and the insights they yield into cognitive and clinical phenomena. In the last decade, the synergistic interaction of neurosurgeons, engineers, and neuroscientists, combined with new technologies, has enabled scientists to study the awake, behaving human brain directly. These developments allow cognitive processes to be characterized at unprecedented resolution: single neuron activity. Direct observation of the human brain has already led to major insights into such aspects of brain function as perception, language, sleep, learning, memory, action, imagery, volition, and consciousness. In this volume, experts document the successes, challenges, and opportunity in an emerging field. The book presents methodological tutorials, with chapters on such topics as the surgical implantation of electrodes and data analysis techniques; describes novel insights into cognitive functions including memory, decision making, and visual imagery; and discusses insights into diseases such as epilepsy and movement disorders gained from examining single neuron activity. Finally, contributors consider future challenges, questions that are ripe for investigation, and exciting avenues for translational efforts. Contributors Ralph Adolphs, William S. Anderson, Arjun K. Bansal, Eric J. Behnke, Moran Cerf, Jonathan O. Dostrovsky, Emad N. Eskandar, Tony A. Fields, Itzhak Fried, Hagar Gelbard-Sagiv, C. Rory Goodwin, Clement Hamani, Chris Heller, Mojgan Hodaie, Matthew Howard III, William D. Hutchison, Matias Ison, Hiroto Kawasaki, Christof Koch, Rüdiger Köhling, Gabriel Kreiman, Michel Le Van Quyen, Frederick A. Lenz, Andres M. Lozano, Adam N. Mamelak, Clarissa Martinez-Rubio, Florian Mormann, Yuval Nir, George Ojemann, Shaun R. Patel, Sanjay Patra, Linda Philpott, Rodrigo Quian Quiroga, Ian Ross, Ueli Rutishauser, Andreas Schulze-Bonhage, Erin M. Schuman, Demetrio Sierra-Mercado, Richard J. Staba, Nanthia Suthana, William Sutherling, Travis S. Tierney, Giulio Tononi, Oana Tudusciuc, Charles L. Wilson

A John Wayne State of Mind

Author : Ian Bailey
Publisher :
ISBN 13 : 9781711692111
Total Pages : 130 pages
Book Rating : 4.6/5 (921 download)

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Book Synopsis A John Wayne State of Mind by : Ian Bailey

Download or read book A John Wayne State of Mind written by Ian Bailey and published by . This book was released on 2019-12-15 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: A John Wayne State of Mind is the second collection of poetry by the Anglo Welsh poet Ian Bailey who lives and works on Mizen Head West Cork. The collection of 41 poems with biographical footnotes were written over the past two years and many of the poems reflect the authors unique experiences on the course of 2019 when in his own words "was bonfired on a pyre of lies in Paris". While he waits further proceedings Ian Bailey continues to write and carve in a haggard near the shore. The cover photograph shows the author selling his first collection The West Cork Way at Skibbereen Saturday market, west Cork, where he has a stall each Saturday

Handbook of MRI Pulse Sequences

Author : Matt A. Bernstein
Publisher : Elsevier
ISBN 13 : 0080533124
Total Pages : 1041 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of MRI Pulse Sequences by : Matt A. Bernstein

Download or read book Handbook of MRI Pulse Sequences written by Matt A. Bernstein and published by Elsevier. This book was released on 2004-09-21 with total page 1041 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI Provides self-contained sections for individual techniques Can be used as a quick reference guide or as a resource for deeper study Includes both non-mathematical and mathematical descriptions Contains numerous figures, tables, references, and worked example problems