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Neuroblastoma
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Download or read book Neuroblastoma written by Sabine Sarnacki and published by Springer. This book was released on 2019-08-12 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses neuroblastoma, a type of embryonic tumor derived from neural crest cells and one of the most frequent extra-cranial solid tumors in children. However, the term also describes a heterogeneous group of tumors, the prognosis of which can differ greatly according to age, stage and biology. Some forms undergo spontaneous regression, and some are cured by surgery alone or after chemo-reduction, while others exhibit extremely aggressive behavior. Their successful treatment is one of the best examples of tailored medicine, which involves close collaboration between pediatric surgeons, pediatric oncologists, radiologists, nuclear medicine specialists, biologists, oncogeneticists and radiotherapists. The book pursues a unique approach, as it combines most essential insights from all of these fields, together with key information regarding epidemiology, physiopathology and palliative care. The respective chapters were written by the leading international experts on neuroblastoma, and present the latest advances in terms of research, surgical approaches and medical treatments. The book offers an invaluable resource to all pediatric surgeons, pediatricians, oncologists, students, researchers and all others involved in neuroblastoma management who want to benefit from their colleagues’ expertise.
Download or read book Neuroblastoma written by Swapan K. Ray and published by Academic Press. This book was released on 2019-01-11 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions. Comprehensively covers the histopathological characterization, molecular mechanisms, and most recent therapeutic interventions in neuroblastoma Includes recent developments and therapeutic interventions for neuroblastoma, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy Presents a broad scope that provides basic researchers, practitioners and students with the most current overview of recent advances
Book Synopsis Neuroblastoma by : Nai-Kong V. Cheung
Download or read book Neuroblastoma written by Nai-Kong V. Cheung and published by Springer Science & Business Media. This book was released on 2006-03-30 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.
Book Synopsis Operative General Surgery in Neonates and Infants by : Tomoaki Taguchi
Download or read book Operative General Surgery in Neonates and Infants written by Tomoaki Taguchi and published by Springer. This book was released on 2016-06-23 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on standard operative techniques for important diseases in pediatric surgery, especially in neonates and infants, while also offering a wealth of schematic drawings and photographs to help readers understand the surgical techniques. Because of the rarity of the diseases and shortage of advising doctors, operative techniques for neonatal and infant surgery are difficult to learn. In order to understand essential operative procedures, schematic drawings and suitable intraoperative photographs are called for. Operative General Surgery in Neonates and Infants was written by leading experts in pediatric surgery with extensive experience in their respective fields. The contents provide detailed practical advice on the surgical procedures and perioperative management in neonates and infants. This book is a valuable guide for trainees and a helpful refresher text for specialized pediatric surgeons and can also be used to explain operative procedures to parents.
Book Synopsis Anterior Skull Base Tumors by : P. Nicolai
Download or read book Anterior Skull Base Tumors written by P. Nicolai and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.
Book Synopsis Pediatric Radiation Oncology by : Thomas E. Merchant
Download or read book Pediatric Radiation Oncology written by Thomas E. Merchant and published by Springer. This book was released on 2018-03-01 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the most up-to-date and innovative information on the targeting and treatment of a wide range of childhood cancers by means of radiation therapy. Written by global experts in pediatric radiation oncology, it documents in detail the treatment regimens appropriate to each disease, highlighting the recent advances that promise to improve rates of survival and cure. The use of image-guided and intensity-modulated radiation therapy is clearly described, and careful attention is also devoted to the roles of proton therapy, stereotactic radiosurgery, stereotactic fractionated radiosurgery, and modulated arc radiotherapy. Separate chapters address localization and verification procedures and anesthesia; pediatric radiation oncology in the palliative care setting; and aspects that are especially relevant in low- and medium-income countries. Beyond clinical radiation oncology, relevant information is provided on radiation physics. The book concludes by examining future directions in the field.
Download or read book Neuroblastoma written by Chandrika Gowda and published by BoD – Books on Demand. This book was released on 2017-10-25 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma.
Book Synopsis Atlas of Pediatric Surgery by : Ahmed H. Al-Salem
Download or read book Atlas of Pediatric Surgery written by Ahmed H. Al-Salem and published by Springer Nature. This book was released on 2020-01-02 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical guide to the congenital and acquired problems related to pediatric surgery and urology. A range of topics are covered, including; abdominal wall hernias, hemangioma and vascular malformations, gastrochesis, achalasia, congenital gastric outlet obstruction, renal and liver tumors, intestinal malrotation, and hydronephrosis. The book aims to be a quick reference text for the diagnosis and treatment of pediatric surgery conditions and presents information relevant to general surgeons, pediatricians, pediatric surgeons, and medical trainees.
Book Synopsis Atlas of PET/CT in Pediatric Patients by : Angelina Cistaro
Download or read book Atlas of PET/CT in Pediatric Patients written by Angelina Cistaro and published by Springer Science & Business Media. This book was released on 2013-11-08 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book presents the pediatric applications of PET/CT in the full range of scenarios frequently encountered in a professional setting. It opens with a thorough introduction covering the fundamental science and the clinical basis for use of PET/CT in this age group. Pitfalls and artifacts are examined, and normal variations and benign findings are carefully described. Each subsequent chapter addresses the role of PET/CT with different radiopharmaceuticals in the evaluation and management of a specific disease. The full range of oncological diseases is covered, including the rare ones. Succinct descriptions of clinical cases are included and, when appropriate, comparisons are made with other modalities. In addition, the role of PET/CT in biopsy guidance and in radiation therapy planning is explained. This book will be invaluable for residents and practitioners in nuclear medicine, radiology, oncology, radiation oncology, and nuclear medicine technology
Book Synopsis Ashcraft's Pediatric Surgery E-Book by : George W. Holcomb
Download or read book Ashcraft's Pediatric Surgery E-Book written by George W. Holcomb and published by Elsevier Health Sciences. This book was released on 2014-01-31 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field. Focus on evidence-based treatments and outcomes to apply today’s best practices. Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout. Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more. Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.
Book Synopsis Target Volume Delineation for Pediatric Cancers by : Stephanie A. Terezakis
Download or read book Target Volume Delineation for Pediatric Cancers written by Stephanie A. Terezakis and published by Springer. This book was released on 2018-12-31 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook is designed to provide the radiation oncologist with clear practical guidance in the delineation of tumor volumes and/or radiation fields for a wide variety of pediatric cancers, including the most frequently encountered malignancies of childhood. This is a guide to designing treatment fields and volumes that may be utilized in the delivery of conformal therapies such as intensity-modulated radiation therapy and proton therapy, the latter being particularly relevant in children. Each chapter focuses on a specific tumor type, providing general guidelines that will assist the reader in delineating the clinical target volume for particular presentations, including patterns of spread. As the target volumes can be complex, detailed illustrations are presented of the volumes in representative cases, contoured slice by slice on the planning CT images. In addition to target volume delineation for conformal treatment, field design setup for conventional approaches is also discussed.
Download or read book Neuroblastoma written by Carl E. Pochedly and published by CRC Press. This book was released on 1990-06-21 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide a comprehensive review of current knowledge and to give a thoughtful assessment of the many complex issues involved in the diagnosis and treatment of this common malignant solid tumor found in children. This up-to-date publication also reviews new concepts in histogenesis and histopathology of neuroblastoma. Divided into three main sections, this work focuses on tumor biology, clinical management, and prognosis and future perspectives. This fascinating work includes in-depth discussions on neuroblastoma in infancy and the manifestations of this tumor as it affects various organs and various parts of the body. It also provides guidelines for treatment with surgery, radiotherapy and chemotherapy. This ideal resource is loaded with information for all those who care for children with cancer, including pediatric oncologists, medical oncologists, pathologists, radiotherapists, pediatric nurse oncologists and pediatricians.
Download or read book Neuroblastoma written by Judy S.E. Moyes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of metaiodobenzylguanidine as a radiopharmaceutical offers exciting new possibilities, and well-known authorities share their experience in this volume. It is designed as a practical aid for those who are starting to employ the relatively new method of mIGB in the diagnosis and treatment of neuroblastoma. Profusely illustrated case histories demonstrate the normal and pathological uptake of mIGB and assist the beginner to correctly interpret the scintigrams. Details of the techniques for assessing the radiation dose to the tumors undergoing targetted radiotherapy are given, and the practical details required for its safe use in the pediatric environment are discussed.
Book Synopsis The Neurology of Neuroblastoma by : Nina Felice Schor
Download or read book The Neurology of Neuroblastoma written by Nina Felice Schor and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood.
Book Synopsis Cancer Incidence and Survival Among Children and Adolescents by :
Download or read book Cancer Incidence and Survival Among Children and Adolescents written by and published by . This book was released on 1999 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuroblastoma by : Shahab Asgharzadeh
Download or read book Neuroblastoma written by Shahab Asgharzadeh and published by Springer Nature. This book was released on with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuroblastoma written by M.A. Hayat and published by Springer Science & Business Media. This book was released on 2011-11-02 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is also included.
