Neural Surface Antigens

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Neural Surface Antigens

Author : Jan Pruszak
Publisher : Academic Press
ISBN 13 : 0128011262
Total Pages : 254 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neural Surface Antigens by : Jan Pruszak

Download or read book Neural Surface Antigens written by Jan Pruszak and published by Academic Press. This book was released on 2015-03-23 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Surface Antigens: From Basic Biology towards Biomedical Applications focuses on the functional role of surface molecules in neural development, stem cell research, and translational biomedical paradigms. With an emphasis on human and rodent model systems, this reference covers fundamentals of neural stem cell biology and flow cytometric methodology. Addressing cell biologists as well as clinicians working in the neurosciences, the book was conceived by an international panel of experts to cover a vast array of particular surface antigen families and subtypes. It provides insight into the basic biology and functional mechanisms of neural cell surface signaling molecules influencing mammalian development, regeneration, and treatments. Introduces early phase clinical trials of neural stem cells Outlines characterization of surface molecule expression and methods for isolation which open unprecedented opportunities for functional study, quantitation & diagnostics Highlights the role of stem cells in neural surface antigen and biomarker analysis and applications

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells

Download Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells PDF Online Free

Author : Vishal Menon
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)

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Book Synopsis Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells by : Vishal Menon

Download or read book Comprehensive Cell Surface Antigen Analysis Identifies Transferrin Receptor Protein-1 (CD71) as a Negative Selection Marker for Human Neuronal Cells written by Vishal Menon and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Cell state-, developmental stage-, and lineage-specific combinatorial expression of cluster of differentiation (CD) molecules enables the identification of cellular subsets via multicolor flow cytometry. We describe an exhaustive characterization of neural cell types by surface antigens, exploiting human pluripotent stem cell-derived neural cell systems. Using multiwell screening approaches followed by detailed validation of expression patterns and dynamics, we exemplify a strategy for resolving cellular heterogeneity in stem cell paradigms. In addition to providing a catalog of surface antigens expressed in the neural lineage, we identified the transferrin receptor-1 (CD71) to be differentially expressed in neural stem cells and differentiated neurons. In this context, we describe a role for N-Myc proto-oncogene (MYCN) in maintaining CD71 expression in proliferating neural cells. We report that in vitro human stem cell-derived neurons lack CD71 surface expression and that the observed differential expression can be used to identify and enrich CD71− neuronal derivatives from heterogeneous cultures

Cell Culture in the Neurosciences

Author : Jane Bottenstein
Publisher : Springer Science & Business Media
ISBN 13 : 1461324734
Total Pages : 392 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Cell Culture in the Neurosciences by : Jane Bottenstein

Download or read book Cell Culture in the Neurosciences written by Jane Bottenstein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fundamental problem in neuroscience is the elucidation of the cellular and molecular mechanisms underlying the development and function of the nervous system. The complexity of organization, the heteroge neity of cell types and their interactions, and the difficulty of controlling experimental variables in intact organisms make this a formidable task. Because of the ability that it affords to analyze smaller components of the nervous system (even single cells in some cases) and to better control experimental variables, cell culture has become an increasingly valuable tool for neuroscientists. Many aspects of neural development, such as proliferation, differentiation, synaptogenesis, and myelination, occur in culture with time courses remarkably similar to those in vivo. Thus, in vitro methods often provide excellent model systems for investigating neurobiological questions. Ross Harrison described the first culture of neural tissue in 1907 and used morphological methods to analyze the cultures. Since that time the technique has been progressively modified and used to address an ever widening range of developmental questions. In recent years a con vergence of new or improved cell culture, biochemical, electrophysiol ogical, and immunological methods has occurred and been brought to bear on neurobiological questions. This volume is intended not to be comprehensive but rather to highlight some of the latest findings, with a review of previous important work as well, in which combinations of these methods are used.

Biochemistry of Characterised Neurons

Author : Neville N. Osborne
Publisher : Elsevier
ISBN 13 : 1483145530
Total Pages : 334 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Biochemistry of Characterised Neurons by : Neville N. Osborne

Download or read book Biochemistry of Characterised Neurons written by Neville N. Osborne and published by Elsevier. This book was released on 2013-10-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the biochemistry of a unique vertebrate (Torpedo) cholinergic system that enables pure cholinergic neuronal cell bodies and endings to be analyzed separately. The sensitive radiochemical procedures used to analyze transmitter substances and transmitter enzymes, and how they can be adapted to map the distribution of transmitters in individual neurons of Aplysia, are discussed in Chapter 8. Chapter 9 describes methods for the analysis of specific cells in the retina, while Chapters 10 and 11 focus on the analysis of proteins within defined neurons. This text is beneficial to biochemists and students interested in analyzing neurons.

Brain Neurotrauma

Author : Firas H. Kobeissy
Publisher : CRC Press
ISBN 13 : 1466565993
Total Pages : 725 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy

Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.

Mapping the Brain and Its Functions

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309044979
Total Pages : 180 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Mapping the Brain and Its Functions by : Institute of Medicine

Download or read book Mapping the Brain and Its Functions written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in brain research have been made, but investigators who face the resulting explosion of data need new methods to integrate the pieces of the "brain puzzle." Based on the expertise of more than 100 neuroscientists and computer specialists, this new volume examines how computer technology can meet that need. Featuring outstanding color photography, the book presents an overview of the complexity of brain research, which covers the spectrum from human behavior to genetic mechanisms. Advances in vision, substance abuse, pain, and schizophrenia are highlighted. The committee explores the potential benefits of computer graphics, database systems, and communications networks in neuroscience and reviews the available technology. Recommendations center on a proposed Brain Mapping Initiative, with an agenda for implementation and a look at issues such as privacy and accessibility.

The Neural Crest

Author : Nicole Le Douarin
Publisher : Cambridge University Press
ISBN 13 : 9780521620109
Total Pages : 494 pages
Book Rating : 4.6/5 (21 download)

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Book Synopsis The Neural Crest by : Nicole Le Douarin

Download or read book The Neural Crest written by Nicole Le Douarin and published by Cambridge University Press. This book was released on 1999-11-28 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: A 1999 edition of a highly successful book describing comprehensive research in the study of the neural crest.

Structural Elements of the Nervous System

Author : Abel Lajtha
Publisher : Springer Science & Business Media
ISBN 13 : 1468445863
Total Pages : 725 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Structural Elements of the Nervous System by : Abel Lajtha

Download or read book Structural Elements of the Nervous System written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemistry, having the objective of elucidating biochemical processes subserving nervous activity, emerged as an application of chemistry to the of neurobiological problems as a post-World War II phenomenon. investigation However, only in the last 40 years has the chemical community recognized neurochemistry as a distinct, if hybrid, discipline. During this period great strides have been made. However, recently neurochemistry, along with neu rophysiology, neuropharmacology, neuroanatomy, and the behavioral sci ences, has emerged to form neuroscience, a new community of scientists with its own national society, journals, and meetings. Actually, this recently formed hybrid, neuroscience, is in the process of merging with another well-established discipline, molecular genetics (frequently called molecular biology, and itself a hybrid), which appears to have sufficient hybrid vigor to form yet a new community of scientists, which, for want of a more imaginative term, has been called molecular genetic neuroscience. Clearly, advantages resulting from such mergers or hybridizations accrue not only from the merging discipline (neurochemistry in this case) to the new community (molecular genetic neuroscience), but also in the reverse direction. This Foreword will be concerned primarily with examples of this latter process.

Neuroimmunology

Author : Bibiana Bielekova
Publisher : Oxford University Press, USA
ISBN 13 : 0190050802
Total Pages : 329 pages
Book Rating : 4.1/5 (9 download)

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Book Synopsis Neuroimmunology by : Bibiana Bielekova

Download or read book Neuroimmunology written by Bibiana Bielekova and published by Oxford University Press, USA. This book was released on 2019 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimmunology, the latest volume in the Contemporary Neurology Series, provides a practical, clinical, and scientific background on a diverse group of neurological disorders in this rapidly expanding field. The book includes chapters on multiple sclerosis and related disorders in adults and children, neuromyelitis optica spectrum disorder, Guillain-Barre Syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and variants, immune-mediated disorders of the neuromuscular junction, inflammatory myopathies, paraneoplastic disorders and autoimmune encephalitities, and neurologic manifestations of systemic immune-mediated diseases. Unique to the work, the authors have included an introductory chapter on the basics of immunology and another on mechanisms of action of therapies used in neuroimmunologic disorders. The clinical chapters cover epidemiology, pathology, pathogenesis, and pathophysiology of the different diseases along with clinical presentation, diagnostic testing, differential diagnosis, and treatment. All are presented in an accessible, practical format, making this volume a valuable resource for physicians and other healthcare providers that will care for persons with neuroimmunologic diseases.

Neural Darwinism

Author : Gerald M. Edelman
Publisher :
ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neural Darwinism by : Gerald M. Edelman

Download or read book Neural Darwinism written by Gerald M. Edelman and published by . This book was released on 1987-12-06 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the nation's leading neuroscientists presents a radically new view of the function of the brain and the nervous system. Its central idea is that the nervous system in each individual operates as a selective system resembling natural selection in evolution, but operating by different mechanisms. This far-ranging theory of brain functions is bound to stimulate renewed discussion of such philosophical issues as the mind-body problem, the origins of knowledge and the perceptual bases of language. Notes and Index.

Advances in Cellular Neurobiology

Author : Sergey Fedoroff
Publisher : Academic Press
ISBN 13 : 1483267873
Total Pages : 472 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Advances in Cellular Neurobiology by : Sergey Fedoroff

Download or read book Advances in Cellular Neurobiology written by Sergey Fedoroff and published by Academic Press. This book was released on 2013-10-22 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cellular Neurobiology, Volume 1 discusses the topographical anatomy and functional relation of the brain and spinal cord. This book is divided into three main sections—cell differentiation and interaction, aging and pathology, and methodologies. The topics discussed include specializations of non-neuronal cell membranes in the vertebrate nervous system; effects of neurohormones on glial cells; cerebellar granule cells in normal and neurological mutants of mice; and age-related changes in neuronal and glial enzyme activities. The glial fibrillary acidic (GFA) protein in normal neural cells and in pathological conditions; in vitro behavior of isolated oligodendrocytes; and biochemical mapping of specific neuronal pathways are also deliberated in this text. This publication is intended for neurologists, but is also beneficial to students researching on the central nervous system.

Virology E-Book

Author : Stephen N J Korsman
Publisher : Elsevier Health Sciences
ISBN 13 : 1455742139
Total Pages : 149 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Virology E-Book by : Stephen N J Korsman

Download or read book Virology E-Book written by Stephen N J Korsman and published by Elsevier Health Sciences. This book was released on 2012-08-17 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, highly accessible introduction to medical virology, incorporating essential basic principles as well as a systematic review of viruses and viral diseases. It pays particular attention to developments in anti-viral therapy that are becoming increasingly effective in modern medicine. It is an ideal textbook for the information-overloaded student and an invaluable everyday companion for the busy professional who needs a good understanding of the current state of medical virology. In keeping with the highly successful format of other Illustrated Colour Texts, it presents the subject as a series of succinct 2 page ‘learning units’, using a superb collection of clear illustrations and clinical photographs, concise yet comprehensive text and key point boxes to aid quick access to information and examination preparation. So whether you are a medical student, junior doctor, medical scientist, trainee in infectious diseases or student on another allied medical course, this book is here to make your life easier! It will also provide a very solid foundation for any who plan to delve deeper into this fascinating field. Part of the popular Illustrated Colour Text series Information presented in double page spreads for easy learning Highly illustrated with both full colour graphics and clinical photographs Each spread includes a key point box for exam preparation

Neuronal and Glial Proteins

Author : Paul Marangos
Publisher : Elsevier
ISBN 13 : 0323151566
Total Pages : 410 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Neuronal and Glial Proteins by : Paul Marangos

Download or read book Neuronal and Glial Proteins written by Paul Marangos and published by Elsevier. This book was released on 2012-12-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuronal and Glial Proteins: Structure, Function, and Clinical Application focuses on the basic and clinical information relating to a number of proteins that are either enriched in or unique to nervous tissue. This book discusses the structural and functional characteristics of cell-specific proteins, which provide a better understanding of the molecular mechanisms involved in processes that are specific to glia or neurons. Organized into three sections encompassing 15 chapters, this book starts with an overview of the fundamental principles and strategies involved in studying the anatomical, structural, functional, and immunological aspects of brain protein. This text then discusses the techniques, including the preparation of brain tissues as well as the preparation of neural and glial cells in purified form. Other chapters review the two-dimensional gel electrophoresis, which is recognized as a significant technique for discovering brain molecules. The final chapter deals with the membrane-associated nervous system proteins. Neurochemists and clinical researchers will find this book useful.

The Chemistry of Inorganic Biomaterials

Author : Christopher Spicer
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017536
Total Pages : 323 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis The Chemistry of Inorganic Biomaterials by : Christopher Spicer

Download or read book The Chemistry of Inorganic Biomaterials written by Christopher Spicer and published by Royal Society of Chemistry. This book was released on 2021-08-18 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book overviews the underlying chemistry behind the most common and cutting-edge inorganic materials in current use, or approaching use, in vivo.

Oxford Textbook of Cognitive Neurology and Dementia

Author : Masud Husain
Publisher : Oxford University Press
ISBN 13 : 0198831080
Total Pages : 513 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Oxford Textbook of Cognitive Neurology and Dementia by : Masud Husain

Download or read book Oxford Textbook of Cognitive Neurology and Dementia written by Masud Husain and published by Oxford University Press. This book was released on 2018-10-29 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers the dramatic developments that have occurred in basic neuroscience and clinical research in cognitive neurology and dementia. It is based on the clinical approach to the patient, and provides essential knowledge that is fundamental to clinical practice.

Current Topics in Developmental Biology

Author :
Publisher : Academic Press
ISBN 13 : 9780080584362
Total Pages : 341 pages
Book Rating : 4.5/5 (843 download)

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Book Synopsis Current Topics in Developmental Biology by :

Download or read book Current Topics in Developmental Biology written by and published by Academic Press. This book was released on 1980-05-27 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Topics in Developmental Biology