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Neue Untersuchungen Mit Gamma Hydroxibuttersaure
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Book Synopsis Neue Untersuchungen mit Gamma-Hydroxibuttersäure by : R. Frey
Download or read book Neue Untersuchungen mit Gamma-Hydroxibuttersäure written by R. Frey and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ziel der Grundlagenforschung in der Anaesthesie ist es, Narkoti ka zu entwickeln, deren Toxizitat minimal ist, die keine zentra le Depression der Atmung bewirken und die frei von Nebenwirkun gen auf die inneren Organe sind. Es ist zu erwarten, daB diese WUnsche des Klinikers am besten von Substanzen erfUllt werden, die aus korpereigenen Stoffen abgeleitet sind oder diesen sogar entsprechen. Ein interessantes parenteral wirkendes Anaesthetikum ist die aus der y-Aminobuttersaure im Zentralnervensystem entstehende y-Hy droxibuttersaure. Das physiologische Vorkommen dieses Substrates hat E. ROBERTS beschrieben (1956), der UmwandlungsprozeB wurde von R. ALBERS und R. SALVATOR aufgeklart. Das Natriumsalz der y-Hydroxibuttersaure wirkt bei intravenoser Injektion schlaf erzeugend, es verursacht keine Ubelkeit, keine Atemdepression und keine organschadigenden Nebenwirkungen. Wenn beispielsweise die per infusionem applizierte Dosis die kinetischen Eigenschaf ten des Wirkstoffes berUcksichtigt, dann laBt sich die Schlaf dauer gut vorprogrammieren. Bei der einmaligen Bolusinjektion hingegen weisen die Schlafzeiten eine gewisse Variationsbreite auf. Die Patienten erwachen, ohne daB unangenehme Traume oder unerwUnschte vegetative Nebenwirkungen bestehen: sie konnen bald wieder aufstehen, bald wieder essen und trinken. Von die sen Eigenschaften habe ich mich im Selbstversuch wiederholt liberzeugen konnen. Auch die Gefahr der Ausbildung einer Sucht besteht nicht. Es ist ein Verdienst der Kohler Chemie, das besonders in Frank reich populare Mittel, das dort in erster Linie von Frau LABORIT klinisch erforscht und empfohlen worden ist, auch in Deutschland auf den Markt gebracht zu haben.
Book Synopsis Neue Aspekte in der Regionalanaesthesie by :
Download or read book Neue Aspekte in der Regionalanaesthesie written by and published by . This book was released on 1980 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The International Journal of the Addictions by :
Download or read book The International Journal of the Addictions written by and published by . This book was released on 1981 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Acta Chirurgica Academiae Scientiarum Hungaricae by :
Download or read book Acta Chirurgica Academiae Scientiarum Hungaricae written by and published by . This book was released on 1980 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology by : Simona Pichini
Download or read book The Challenge Posed by New Synthetic Opioids: Pharmacology and Toxicology written by Simona Pichini and published by Frontiers Media SA. This book was released on 2019-08-19 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Synthetic Opioids (NSOs), most of which are illegally produced and sold for recreational use, are posing a serious threat to the health of consumers. Due to the low cost of materials and equipment required for clandestine laboratories production with respect to the production cost of heroin, NSOs are climbing the illegal street and web drug market. Several of these drugs have been involved in a recent rise in acute intoxications and overdose deaths. Since NSOs offer enormous profit potential, and there is strong demand for their use, these drugs are being trafficked by organized crime and present major challenges for medical professionals facing intoxications and fatalities, law enforcement agencies fighting against their diffusion and policymakers trying to restrain the use and abuse of NSOs. This Research Topic aimed to fill the gap on current knowledge on pharmacology and toxicology, health risks for adult and newborns of NSOs covering both basic scientific as well as epidemiological and clinical aspects. 3 reviews, 3 mini-reviews, 1 original article, 2 case reports and 1 opinion are here presented.
Book Synopsis Drug-Facilitated Sexual Assault by : Marc A. LeBeau
Download or read book Drug-Facilitated Sexual Assault written by Marc A. LeBeau and published by Elsevier. This book was released on 2001-08-28 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Facilitated Sexual Assault educates readers on the ways in which drugs are used as weapons in committing sexual assaults and how to successfully investigate these crimes. It looks at the history of these crimes over the years, and includes an in-depth discussion of the drugs and drug classes in use today. It describes the effects of these drugs on the victims, the process for reporting these crimes, details on the type of person who uses drugs to sexually assault an individual, and obstacles to investigating the suspect. The authors show the proper techniques in collecting and analyzing evidence; ways to overcome some of the unique difficulties encountered in these types of investigations; and how to work with other professionals to prosecute these cases successfully. The concluding appendixes are valuable samples of the necessary forms needed to complete these investigations. This book is ideal for anyone involved in investigating these crimes, including forensic scientists, law enforcement officers, lawyers, toxicologists, and medical professionals. * Ideal for everyone involved in the investigation of these crimes, including forensic scientists, police officers, lawyers, toxicologists and medical professionals
Book Synopsis Neuropathology of Drug Abuse by : Andreas Büttner
Download or read book Neuropathology of Drug Abuse written by Andreas Büttner and published by Springer Nature. This book was released on 2020-10-27 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current state of knowledge concerning neuropathologies resulting from drug abuse. The first chapters offer readers detailed information on the neurobiological basics of drug abuse and the results of neuroimaging studies in drug abusers. The focus of the book is on neuropathological findings in drug abusers for the predominant substances, which include cannabis, opiates, cocaine, amphetamine, methamphetamine and a broad spectrum of designer drugs. These findings are supported by histological illustrations and discussed in connection with recent scientific publications. A chapter specifically addressing clinicians is also included, and highlights the implications for further therapy. The book is essential reading for neuropathologists, neurologists, neuroradiologists and psychiatrists, as well as other health professionals and scientists interested and engaged in the problem of drug abuse. Although a great deal of data has been derived from animal models and from human neuroimaging studies, little is known about the morphological effects of drug abuse on the human brain. In recent years, fundamental drug-induced effects on the cellular elements of the brain have been detected. These alterations might not only be the substrate of the neuroimaging data but might also have implications for clinical research and therapy. In addition, drug abuse may induce premature neurodegeneration.
Book Synopsis Clinical Management of Poisoning and Drug Overdose by : Lester M. Haddad
Download or read book Clinical Management of Poisoning and Drug Overdose written by Lester M. Haddad and published by . This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here's a comprehensive and clinically-specific reference on toxicology. The 3rd Edition includes chapters on overdose during rapid-sequence intubation and conscious sedation, management of complications of thrombolytic agents, and the application of hyperbaric medicine in toxicology. Provides the perfect balance of basic pharmacokinetics and clinical management. Contributions are by experts in the field. Contains completely rewritten and reorganized coverage to encompass the background, pharmacology, pathophysiology, diagnosis, and management of each toxin for clinical treatment throughout a patient's hospital stay. Features a new editor--Michael Shannon, MD--whose experience in pediatric emergency medicine expands the text's coverage of pediatrics...and almost 60 new contributing experts who have made original contributions to their field, with a majority certified by the first approved subspecialty board in toxicology. Presents 10 new chapters that cover: pediatric resuscitation, antibiotic hypersensitivity and anaphylaxis, MAO inhibitors and the serotonin syndrome, herbal and alternative medicine, and thrombolytic therapy, and more. OUTSTANDING FEATURES: Uses a clinical approachfor maximum clinical relevance, addressing how toxins affect humans, not animals. Incorporates the experience of many expert authors from numerous specialties for a Comprehensive review of toxicology and an authoritative overview of each specialty. Contains colour plates of toxic natural life, including various snakes, mushrooms, plants, and marine life--a feature unique to this book.
Book Synopsis International Practice of Anaesthesia by : Cedric Prys-Roberts
Download or read book International Practice of Anaesthesia written by Cedric Prys-Roberts and published by . This book was released on 1996 with total page 1316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Timeline Followback by : Linda C. Sobell
Download or read book Timeline Followback written by Linda C. Sobell and published by Addiction Research Foundation. This book was released on 1996 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: A calendar method for assessing alcohol and drug use.
Book Synopsis Incorporating Alcohol Pharmacotherapies Into Medical Practice by : Eric C. Strain
Download or read book Incorporating Alcohol Pharmacotherapies Into Medical Practice written by Eric C. Strain and published by DIANE Publishing. This book was released on 2010-10 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many health problems that healthcare practitioners encounter derive from or are complicated by alcohol use disorders (AUD). Four approved medications that treat AUD make treatment in primary care a viable adjunct or alternative to specialty care, with many potential advantages. Screening for and providing brief interventions to treat AUD in general medical settings promote healthy life choices and increase the likelihood of recovery, especially for patients who have not yet progressed to chronic alcohol dependence, those with comorbid medical disorders being treated in these settings, and those who otherwise would not seek or receive treatment for their AUD. This report provides a resource to assist the health-care provider in this effort. Illus.
Book Synopsis Psychopharmacology by : Herbert Y. Meltzer
Download or read book Psychopharmacology written by Herbert Y. Meltzer and published by Raven Press (ID). This book was released on 1987 with total page 1828 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis 2020 Handbook of Emergency Cardiovascular Care for Healthcare Providers by : American Heart Association
Download or read book 2020 Handbook of Emergency Cardiovascular Care for Healthcare Providers written by American Heart Association and published by . This book was released on 2020-10-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: 20-1100
Book Synopsis Polyhydroxyalkanoates--plastic Materials of the 21st Century by : Tatʹi͡ana Grigorʹevna Volova
Download or read book Polyhydroxyalkanoates--plastic Materials of the 21st Century written by Tatʹi͡ana Grigorʹevna Volova and published by Nova Publishers. This book was released on 2004 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Special Interest Catogories: biotechnology; materials science; medicine; ecology and chemistry. The book summarizes the literature data and research results on biodegradable polyesters of microbiological origin -- polymers of hydroxy alkanoic acids (polyhydroxyalkanoates, PHAs). These polymers are thermoplastic, biodegradable, and biocompatible. They are promising candidates for applications in agriculture, communal services, pharmacology, medicine, and other spheres. The book sums up the most recent data on the known types of polyhydroxyalkanoates, their producers, substrates, and methods of biosynthesis. The structure and physicochemical properties of these polymers, the methods used to process them to make specialised products and spheres of their application are described in the book.
Book Synopsis The Handbook of Polyhydroxyalkanoates by : Martin Koller
Download or read book The Handbook of Polyhydroxyalkanoates written by Martin Koller and published by CRC Press. This book was released on 2023-09-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers kinetics, bioengineering and industrial aspects and focusses on thermodynamic and mathematical considerations of PHA biosynthesis, bioengineering aspects regarding bioreactor design and downstream processing for PHA recovery from microbial biomass.
Book Synopsis Modern Anesthetics by : Jürgen Schüttler
Download or read book Modern Anesthetics written by Jürgen Schüttler and published by Springer Science & Business Media. This book was released on 2008-01-08 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some important constraints of anesthesia must be taken into consideration when the pharmacological properties of modern anesthetics are discussed. The most imp- tant of these could be that the target effect be achieved preferably within seconds, at most within a few minutes. Similarly, offset of drug action should be achieved within minutes rather hours. The target effects, such as unconsciousness, are pot- tially life-threatening, as are the side effects of modern anesthetics, such as respi- tory and cardiovascular depression. Finally, the patient’s purposeful responses are not available to guide drug dosage, because, either the patient is unconscious, or more problematically, the patient is aware but unable to communicate pain because of neuromuscular blockade. These constraints were already recognised 35 years ago, when in 1972 Volume XXX entitled “Modern Inhalation Anesthetics” appeared in this Handbook Series. The present volume is meant as a follow up and extension of that volume. At the beginning of the 1970’s anesthesia was commonly delivered by inhalation, with only very few exceptions. The clinical understanding of that time considered anesthesia as a unique state achieved by any of the inhalation anesthetics, in- pendent of their specific molecular structure. “The very mechanism of anesthetic action at the biophase” was discussed within the theoretical framework of the “u- tary theory of narcosis”.
Book Synopsis Happy Pills in America by : David Herzberg
Download or read book Happy Pills in America written by David Herzberg and published by JHU Press. This book was released on 2010-10-01 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Valium. Paxil. Prozac. Prescribed by the millions each year, these medications have been hailed as wonder drugs and vilified as numbing and addictive crutches. Where did this “blockbuster drug” phenomenon come from? What factors led to the mass acceptance of tranquilizers and antidepressants? And how has their widespread use affected American culture? David Herzberg addresses these questions by tracing the rise of psychiatric medicines, from Miltown in the 1950s to Valium in the 1970s to Prozac in the 1990s. The result is more than a story of doctors and patients. From bare-knuckled marketing campaigns to political activism by feminists and antidrug warriors, the fate of psychopharmacology has been intimately wrapped up in the broader currents of modern American history. Beginning with the emergence of a medical marketplace for psychoactive drugs in the postwar consumer culture, Herzberg traces how “happy pills” became embroiled in Cold War gender battles and the explosive politics of the “war against drugs”—and how feminists brought the two issues together in a dramatic campaign against Valium addiction in the 1970s. A final look at antidepressants shows that even the Prozac phenomenon owed as much to commerce and culture as to scientific wizardry. With a barrage of “ask your doctor about” advertisements competing for attention with shocking news of drug company malfeasance, Happy Pills is an invaluable look at how the commercialization of medicine has transformed American culture since the end of World War II.
