Neonatal Encephalopathy and Cerebral Palsy

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Author :
Publisher : American College of Obstetricians and Gynecologists Women's Health Care Physicians
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neonatal Encephalopathy and Cerebral Palsy by : American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy

Download or read book Neonatal Encephalopathy and Cerebral Palsy written by American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy and published by American College of Obstetricians and Gynecologists Women's Health Care Physicians. This book was released on 2003 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph explores the mechanisms and timing of possible etiologic events that contribute to fetal and neonatal neurologic injury. the report presents evidence that most cases of cerebral palsy are a result of multifactorial and unpreventable causes that occur during fetal development or in the newborn after delivery, and not a result of an isolated intrapartum hypoxic event. the report contains a set of criteria that may be used to define (or rule out) an acute intrapartum hypoxic event sufficient to cause or suggest cerebral palsy.

Neonatal Encephalopathy and Neurologic Outcome

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Publisher : American College of Obstetricians and Gynecologists Women's Health Care Physicians
ISBN 13 : 9781934984307
Total Pages : 0 pages
Book Rating : 4.9/5 (843 download)

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Book Synopsis Neonatal Encephalopathy and Neurologic Outcome by : American College of Obstetricians and Gy

Download or read book Neonatal Encephalopathy and Neurologic Outcome written by American College of Obstetricians and Gy and published by American College of Obstetricians and Gynecologists Women's Health Care Physicians. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.

Pediatric Neurology Part I

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Author :
Publisher : Elsevier Inc. Chapters
ISBN 13 : 0128077212
Total Pages : 27 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Pediatric Neurology Part I by : Stéphane Marret

Download or read book Pediatric Neurology Part I written by Stéphane Marret and published by Elsevier Inc. Chapters. This book was released on 2013-04-24 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral palsy (CP), defined as a group of nonprogressive disorders of movement and posture, is the most common cause of severe neurodisability in children. Understanding its physiopathology is crucial to developing some protective strategies. Interruption of oxygen supply to the fetus or brain asphyxia was classically considered to be the main causal factor explaining later CP. However several ante-, peri-, and postnatal factors could be involved in the origins of CP syndromes. Congenital malformations are rarely identified. CP is most often the result of environmental factors, which might interact with genetic vulnerabilities, and could be severe enough to cause the destructive injuries visible with standard imaging (i.e., ultrasonographic study or MRI), predominantly in the white matter in preterm infants and in the gray matter and the brainstem nuclei in full-term newborns. Moreover they act on an immature brain and could alter the remarkable series of developmental events. Biochemical key factors originating in cell death or cell process loss, observed in hypoxic−ischemic as well as inflammatory conditions, are excessive production of proinflammatory cytokines, oxidative stress, maternal growth factor deprivation, extracellular matrix modifications, and excessive release of glutamate, triggering the excitotoxic cascade. Only two strategies have succeeded in decreasing CP in 2-year-old children: hypothermia in full-term newborns with moderate neonatal encephalopathy and administration of magnesium sulfate to mothers in preterm labor.

Birth Asphyxia, An Issue of Clinics in Perinatology, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323462847
Total Pages : 20 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Birth Asphyxia, An Issue of Clinics in Perinatology, E-Book by : Beena D. Kamath-Rayne

Download or read book Birth Asphyxia, An Issue of Clinics in Perinatology, E-Book written by Beena D. Kamath-Rayne and published by Elsevier Health Sciences. This book was released on 2016-08-19 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Guest Editors have assembled top experts to provide the most current and clinically relevant articles devoted to Birth Asyphyxia. Articles in this issue are devoted to: Neonatal Transition After Birth; Pathophysiology of Birth Asphyxia; Perinatal Asphyxia from the Obstetrical Standpoint: Diagnosis and Interventions; Stillbirths: U.S. and Global Perspectives; Novel Approaches to Resuscitation and the Impact on Birth Asphyxia; Multiorgan Dysfunction and its Management After Birth Asphyxia; Neonatal Encephalopathy and Update on Therapeutic Hypothermia and Other Novel Therapeutics; Biomarkers in Neonatal Encephalopathy; Imaging and Other Diagnostics in Neonatal Encephalopathy; Asphyxia in the Premature Infant; The role of the NeoNeuro Unit for Birth Asphyxia; Long-term Cognitive Outcomes of Birth Asphyxia and the Contribution of Identified Perinatal Asphyxia to Cerebral Palsy; Global Burden, Epidemiologic Trends, and Prevention of Intrapartum Related Deaths in Low-resource Settings; and Neonatal Resuscitation in Low-resource Settings.

Epidemiology of Cerebral Palsy and Unfavourable Neurodevelopmental Outcome in Child Population of Tartu City and County, Estonia

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Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.6/5 (927 download)

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Book Synopsis Epidemiology of Cerebral Palsy and Unfavourable Neurodevelopmental Outcome in Child Population of Tartu City and County, Estonia by : Tiina Stelmach

Download or read book Epidemiology of Cerebral Palsy and Unfavourable Neurodevelopmental Outcome in Child Population of Tartu City and County, Estonia written by Tiina Stelmach and published by . This book was released on 2006 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Newborn Brain

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Publisher : Cambridge University Press
ISBN 13 : 113948558X
Total Pages : 427 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Newborn Brain by : Hugo Lagercrantz

Download or read book The Newborn Brain written by Hugo Lagercrantz and published by Cambridge University Press. This book was released on 2010-01-07 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.

Improving outcomes in cerebral palsy with early intervention: new translational approaches

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Author :
Publisher : Frontiers E-books
ISBN 13 : 2889195120
Total Pages : 156 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Improving outcomes in cerebral palsy with early intervention: new translational approaches by : Anna Purna Basu

Download or read book Improving outcomes in cerebral palsy with early intervention: new translational approaches written by Anna Purna Basu and published by Frontiers E-books. This book was released on 2015-03-30 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life. CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults. We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist.

Acute Perinatal Asphyxia in Term Infants

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Publisher : DIANE Publishing
ISBN 13 : 9780788145445
Total Pages : 220 pages
Book Rating : 4.1/5 (454 download)

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Book Synopsis Acute Perinatal Asphyxia in Term Infants by : Linda L. Wright

Download or read book Acute Perinatal Asphyxia in Term Infants written by Linda L. Wright and published by DIANE Publishing. This book was released on 1997-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews the current knowledge of the definition & diagnosis of acute perinatal asphyxia in term infants in order to develop operational & specific criteria to be tested in new studies. Summarized information currently available on this topic. Contents: scientific basis of brain injury in acute perinatal asphyxia; clinical assessment -- obstetrics; clinical assessment -- neonatal; interventions (conventional management; neuronal rescue & neuronal prohylaxis; glutamate antagonists, calcium channel blockers & Allopurinol); clinical studies of long-term outcome; clinical research. Charts & tables.

Cell Therapy for Perinatal Brain Injury

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Publisher : Springer
ISBN 13 : 9811014124
Total Pages : 155 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Cell Therapy for Perinatal Brain Injury by : Haruo Shintaku

Download or read book Cell Therapy for Perinatal Brain Injury written by Haruo Shintaku and published by Springer. This book was released on 2018-03-01 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy.

Fetal and Neonatal Brain Injury

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Publisher : Cambridge University Press
ISBN 13 : 9780521806916
Total Pages : 932 pages
Book Rating : 4.8/5 (69 download)

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Book Synopsis Fetal and Neonatal Brain Injury by : David K. Stevenson

Download or read book Fetal and Neonatal Brain Injury written by David K. Stevenson and published by Cambridge University Press. This book was released on 2003-02-06 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its third edition, this is a comprehensive survey of fetal and neonatal brain injury arising from hypoxia, ischemia or other causes. The volume spans a broad range of areas from epidemiology and pathogenesis, through to clinical manifestations and obstetric care, and then on to diagnosis, long-term outcomes, and medico-legal aspects. An important theme running throughout is to highlight scientific and clinical advances that have a role to play in minimising risk, improving clinical care and outcomes.

Preventing Developmental Brain Injury – From Animal Models to Clinical Trials

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889630757
Total Pages : 316 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Preventing Developmental Brain Injury – From Animal Models to Clinical Trials by : Masahiro Tsuji

Download or read book Preventing Developmental Brain Injury – From Animal Models to Clinical Trials written by Masahiro Tsuji and published by Frontiers Media SA. This book was released on 2019-10-23 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ADHD Rating Scale?5 for Children and Adolescents

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Author :
Publisher : Guilford Publications
ISBN 13 : 1462524877
Total Pages : 137 pages
Book Rating : 4.4/5 (625 download)

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Book Synopsis ADHD Rating Scale?5 for Children and Adolescents by : George J. DuPaul

Download or read book ADHD Rating Scale?5 for Children and Adolescents written by George J. DuPaul and published by Guilford Publications. This book was released on 2016-02-15 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by ADHD rating scale-IV / George J. DuPaul ... [et al.]. 1998.

Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

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Publisher : Springer Science & Business Media
ISBN 13 : 366202568X
Total Pages : 734 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Magnetic Resonance of Myelin, Myelination, and Myelin Disorders by : Jacob Valk

Download or read book Magnetic Resonance of Myelin, Myelination, and Myelin Disorders written by Jacob Valk and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.

Cerebral Palsy

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Publisher : JHU Press
ISBN 13 : 0801883547
Total Pages : 537 pages
Book Rating : 4.8/5 (18 download)

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Book Synopsis Cerebral Palsy by : Freeman Miller

Download or read book Cerebral Palsy written by Freeman Miller and published by JHU Press. This book was released on 2006-05-08 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: When a child has a health problem, parents want answers. But when a child has cerebral palsy, the answers don't come quickly. A diagnosis of this complex group of chronic conditions affecting movement and coordination is difficult to make and is typically delayed until the child is eighteen months old. Although the condition may be mild or severe, even general predictions about long-term prognosis seldom come before the child's second birthday. Written by a team of experts associated with the Cerebral Palsy Program at the Alfred I. duPont Hospital for Children, this authoritative resource provides parents and families with vital information that can help them cope with uncertainty. Thoroughly updated and revised to incorporate the latest medical advances, the second edition is a comprehensive guide to cerebral palsy. The book is organized into three parts. In the first, the authors describe specific patterns of involvement (hemiplegia, diplegia, quadriplegia), explain the medical and psychosocial implications of these conditions, and tell parents how to be effective advocates for their child. In the second part, the authors provide a wealth of practical advice about caregiving from nutrition to mobility. Part three features an extensive alphabetically arranged encyclopedia that defines and describes medical terms and diagnoses, medical and surgical procedures, and orthopedic and other assistive devices. Also included are lists of resources and recommended reading.

Cerebral Palsies

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Publisher : Cambridge University Press
ISBN 13 : 9781898683209
Total Pages : 280 pages
Book Rating : 4.6/5 (832 download)

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Book Synopsis Cerebral Palsies by : Fiona J. Stanley

Download or read book Cerebral Palsies written by Fiona J. Stanley and published by Cambridge University Press. This book was released on 2000-01-18 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This totally new clinical text gives: • Guidance on how best to study causes • An account and analysis of international research • Methods of collection and analysis of data • A review of all published data • New ways of thinking about causal pathways in the cerebral palsies • Possible new prevention pathways • A guide to systematic management

Neonatal Neural Rescue

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Publisher : Cambridge University Press
ISBN 13 : 1107328845
Total Pages : 245 pages
Book Rating : 4.1/5 (73 download)

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Book Synopsis Neonatal Neural Rescue by : A. David Edwards

Download or read book Neonatal Neural Rescue written by A. David Edwards and published by Cambridge University Press. This book was released on 2013-04-04 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Worldwide more than one million babies die annually from perinatal asphyxia and its associated complications such as neonatal encephalopathy – one of the major causes of cerebral palsy and cognitive deficiencies in children aside from prematurity. Cooling the head – or the entire body – minimizes neuronal death, enabling the neonatal brain to be 'rescued' thus greatly improving developmental outcomes. Hypothermic neural rescue therapy has revolutionized the treatment of this condition and is a major recent achievement in neonatal medicine. This landmark book provides a brief scientific underpinning of hypothermic neural rescue therapy and lays out the evidence base for good practice. Internationally recognized authorities give practical advice, drawn from personal experience, on how to deliver hypothermia in the neonatal intensive care unit. A valuable addition to any neonatal unit, this is essential reading for neonatologists, neonatal nurses and paediatric neurologists.

The Epilepsies

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Publisher : Springer
ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Epilepsies by : Chrysostomos P. Panayiotopoulos

Download or read book The Epilepsies written by Chrysostomos P. Panayiotopoulos and published by Springer. This book was released on 2005 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.