Natural Products as Anticancer Agents

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Author :
Publisher : Elsevier
ISBN 13 : 0323997112
Total Pages : 444 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Natural Products as Anticancer Agents by : Bimal Krishna Banik

Download or read book Natural Products as Anticancer Agents written by Bimal Krishna Banik and published by Elsevier. This book was released on 2023-11-21 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products as Anticancer Agents introduces the different types of natural products that have been used for cancer treatment. Divided into four parts, covering anticancer agents derived from terrestrial plants, anticancer agents derived from the marine environment, and anticancer agents derived from microorganisms, as well as evaluation of new anticancer agents, each part includes discussion of the properties, synthesis/extraction, storage, mechanism of action, and usage of the molecules. Discussion of the future prospects in anticancer natural products—including several new trends and an indication of where research in this area is likely to go in the future—is also included. Assists in the identification of risk factors associated with the drug development process Includes process diagrams detailing the procedure for the isolation and purification of molecules Covers cost-effective green approaches in the development of anticancer drugs

Anticancer Agents from Natural Products

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Author :
Publisher : CRC Press
ISBN 13 : 1420039652
Total Pages : 610 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Anticancer Agents from Natural Products by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products written by Gordon M. Cragg and published by CRC Press. This book was released on 2005-06-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants, marine organisms, and microorganisms have evolved complex chemical defense and signaling systems that are designed to protect them from predators and provide other biological benefits. These organisms thus produce substances containing novel chemotypes that may have beneficial effects for humans. As collection methods improve and new screen

Discovery and Development of Anti-Breast Cancer Agents from Natural Products

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Publisher : Elsevier
ISBN 13 : 0128212780
Total Pages : 386 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Discovery and Development of Anti-Breast Cancer Agents from Natural Products by : Goutam Brahmachari

Download or read book Discovery and Development of Anti-Breast Cancer Agents from Natural Products written by Goutam Brahmachari and published by Elsevier. This book was released on 2021-06-24 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields. Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area. Highlights active agents from natural sources for development as novel anti-cancer agents Features contributions from active researchers and leading experts working in the field Includes foundational background information on both breast cancer mechanisms and natural product structures to support researchers from different disciplines

Anticancer Agents from Natural Products, Second Edition

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Publisher : CRC Press
ISBN 13 : 1439813825
Total Pages : 786 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Anticancer Agents from Natural Products, Second Edition by : Gordon M. Cragg

Download or read book Anticancer Agents from Natural Products, Second Edition written by Gordon M. Cragg and published by CRC Press. This book was released on 2011-10-10 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: The approach to drug discovery from natural sources has yielded many important new pharmaceuticals inaccessible by other routes. In many cases the isolated natural product may not be an effective drug for any of several reasons, but it nevertheless may become a drug through chemical modification or have a novel pharmacophore for future drug design. In summarizing the status of natural products as cancer chemotherapeutics, Anticancer Agents from Natural Products, Second Edition covers the: History of each covered drug—a discussion of its mechanism on action, medicinal chemistry, synthesis, and clinical applications Potential for novel drug discovery through the use of genome mining as well as future developments in anticancer drug discovery Important biosynthetic approaches to "unnatural" natural products Anticancer Agents from Natural Products, Second Edition discusses how complex target-oriented synthesis—enabled by historic advances in methodology—has enormously expanded the scope of the possible. This book covers the current clinically used anticancer agents that are either natural products or are clearly derived from natural product leads. It also reviews drug candidates currently in clinical development since many of these will be clinically used drugs in the future. Examples include the drugs etoposide and teniposide derived from the lead compound podophyllotoxin; numerous analogs derived from taxol; topotecan, derived from camptothecin; and the synthetic clinical candidates, E7389 and HTI-286, developed from the marine leads, halichondrin B and hemiasterlin.

Natural Products and Cancer Drug Discovery

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461446546
Total Pages : 248 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Natural Products and Cancer Drug Discovery by : Frank E. Koehn

Download or read book Natural Products and Cancer Drug Discovery written by Frank E. Koehn and published by Springer Science & Business Media. This book was released on 2012-11-09 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools for new target generation , new approaches to cancer drug discovery through natural products based lead generation, and enabling technologies which leverage the unique attributes of natural products.

Natural Products for Cancer Prevention and Therapy

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Author :
Publisher : MDPI
ISBN 13 : 3038973106
Total Pages : 285 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Natural Products for Cancer Prevention and Therapy by : Anupam Bishayee

Download or read book Natural Products for Cancer Prevention and Therapy written by Anupam Bishayee and published by MDPI. This book was released on 2018-11-07 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Natural Products for Cancer Prevention and Therapy" that was published in Nutrients

Anticancer Plants: Natural Products and Biotechnological Implements

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Author :
Publisher : Springer
ISBN 13 : 981108064X
Total Pages : 564 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Anticancer Plants: Natural Products and Biotechnological Implements by : Mohd Sayeed Akhtar

Download or read book Anticancer Plants: Natural Products and Biotechnological Implements written by Mohd Sayeed Akhtar and published by Springer. This book was released on 2018-07-02 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides summarized scientific evidence of the different classes of plant-derived phytocompounds, their sources, chemical structures, anticancer properties, mechanisms of action, methods of extraction, and their applications in cancer therapy. It also discusses endophyte-derived compounds as chemopreventives to treat various cancer types. In addition, it provides detailed information on the enhanced production of therapeutically valuable anticancer metabolites using biotechnological interventions such as plant cell and tissue culture approaches, including in vitro-, hairy root- and cell-suspension culture; and metabolic engineering of biosynthetic pathways. Anticancer Plants: Natural Products and Biotechnological Implements – Volume 2” explores the natural bioactive compounds isolated from plants as well as fungal endophytes, their chemistry, and preventive effects to reduce the risk of cancer. Moreover, it highlights the genomics/proteomics approaches and biotechnological implementations. Providing solutions to deal with the challenges involved in cancer therapy, the book benefits a wide range of readers including academics, students, and industrial experts working in the area of natural products, medicinal plant chemistry, pharmacology, and biotechnology.

Marine Natural Products as Anticancer Agents 2.0

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Author :
Publisher : Mdpi AG
ISBN 13 : 9783036575681
Total Pages : 0 pages
Book Rating : 4.5/5 (756 download)

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Book Synopsis Marine Natural Products as Anticancer Agents 2.0 by : Celso Alves

Download or read book Marine Natural Products as Anticancer Agents 2.0 written by Celso Alves and published by Mdpi AG. This book was released on 2023-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, "Marine Natural Products as Anticancer Agents 2.0", gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents.

New Approaches to Natural Anticancer Drugs

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Publisher : Springer
ISBN 13 : 3319140272
Total Pages : 117 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis New Approaches to Natural Anticancer Drugs by : Soodabeh Saeidnia

Download or read book New Approaches to Natural Anticancer Drugs written by Soodabeh Saeidnia and published by Springer. This book was released on 2015-02-05 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date review of recently identified natural anti-tumor compounds from various natural origins including plants, fungi, endophytic fungi and marine organisms. It also includes discussion of new areas such as biotechnology and nanoparticles. Chapters explain the challenges and developments in anti-cancer drug discovery approaches, traditional remedies for prevention and treatment of cancer, marine-derived anti-cancer compounds, and antibiotics used as anti-cancer agents, as well as different classes of terpenoids and carbohydrates, which have been the subject of discussion in this field as efficient anti-cancer candidates. This book will be a concise guide for researchers in the field of pharmaceutical sciences, students and residents in pharmacy and medicine as well as those researching phytochemistry and natural products.

Natural Products and Their Bioactive Compounds As Cancer Therapeutics

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Author :
Publisher : Medical Information Science Reference
ISBN 13 : 9781799892588
Total Pages : 400 pages
Book Rating : 4.8/5 (925 download)

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Book Synopsis Natural Products and Their Bioactive Compounds As Cancer Therapeutics by : Ashok Kumar Pandurangan

Download or read book Natural Products and Their Bioactive Compounds As Cancer Therapeutics written by Ashok Kumar Pandurangan and published by Medical Information Science Reference. This book was released on 2022 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The main objective of this book is to emphasize the list of natural agents against all type of cancers and show the current state of research in the fields of natural products and their derivatives against cancer in preclinical and clinical models"--

Handbook of Anticancer Drugs from Marine Origin

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Publisher : Springer
ISBN 13 : 3319071459
Total Pages : 801 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Handbook of Anticancer Drugs from Marine Origin by : Se-Kwon Kim

Download or read book Handbook of Anticancer Drugs from Marine Origin written by Se-Kwon Kim and published by Springer. This book was released on 2014-11-27 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.

Natural Products

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Publisher : Springer Science & Business Media
ISBN 13 : 1592599761
Total Pages : 380 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Natural Products by : Lixin Zhang

Download or read book Natural Products written by Lixin Zhang and published by Springer Science & Business Media. This book was released on 2007-11-17 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.

Lead Molecules from Natural Products

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Author :
Publisher : Elsevier
ISBN 13 : 9780080459332
Total Pages : 448 pages
Book Rating : 4.4/5 (593 download)

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Book Synopsis Lead Molecules from Natural Products by :

Download or read book Lead Molecules from Natural Products written by and published by Elsevier. This book was released on 2006-07-07 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics ranging from Natural Product Chemistry and Phytochemistry in their most basic form, to Molecular Biology and in silico drug design. Contributors describe their own laboratory experiences, revealing their findings, the legal issues encountered. The chapters, all of equally high quality, summarize years of extensive research in each area, and provide insight in the new themes of natural product research. The information will help to predict promising leads, useful for physicians in the treatment of different diseases and disease manifestations. * Explains the effects of plant extracts on gene expression profiling. * Details medicinal plant research from around the world * Explores a variety of medicinal uses of plants from traditional remedies, to anti-cancer agents and anti-salmonella agents.

Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9815124706
Total Pages : 325 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach by : Motamarri Venkata Naga Lalitha Chaitanya

Download or read book Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach written by Motamarri Venkata Naga Lalitha Chaitanya and published by Bentham Science Publishers. This book was released on 2023-11-02 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a holistic view of natural products and remedies that have been used to treat cancer. The editors aim to educate readers about the importance of the translational role of natural products in cancer treatment by compiling 14 chapters. The book emphasizes an integrative approach to the topic by blending traditional knowledge that supports alternative therapies with the science of phytochemicals and drug discovery technologies as a means to manage the disease. Key topics include alternative therapies (such as aromatherapy and immune boosting herbal medications), cytotoxic and anti-cancer phytochemicals, drug delivery and discovery technologies (including high-throughput screening) and some drug targets of interest for cancer treatment (such as topoisomerases and caspases). Readers will be able to learn about natural sources of ant-cancer compounds, and the methods used by research and development experts in pharmaceutical and nutraceutical industries to isolate and formulate these compounds. This book will be a handy resource for a wide range of readers. This includes researchers, traditional medical practitioners, PG students, Ph.D. scholars and general readers to understand the role of natural products in cancer treatment. key features - Explains the importance of alternative therapies in the management of cancer - Emphasizes the ethnopharmacological approaches to cancer - Explores natural anticancer drug libraries - Discusses the role of modern cancer targets and the importance of in-silico tools in anticancer drug discovery - Addresses modern drug discovery tools and drug delivery technologies concerning their applications in cancer treatment. - Includes references for further reading

Natural Products and Cancer Drug Discovery

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535133136
Total Pages : 318 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Natural Products and Cancer Drug Discovery by : Farid A. Badria

Download or read book Natural Products and Cancer Drug Discovery written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2017-07-05 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, Natural Products and Cancer Drug Discovery, is written by leading experts in natural products in cancer therapy. The first two sections describe new applications of common herbs and foods for treatment of cancer. Section 3 deals with the development of new chemotherapeutics from Cannabis and endophytic fungi. Section 4 presented formulations of natural products for treatment of malignant melanoma. Made-to-order anticancer therapy from natural products using computational and tissue engineering approaches is addressed in the fifth section. It is our hope that this book may motivate readers to approach the evidence of anticancer natural products with an open mind and thereby spark an interest in making further contributions to the cancer treatment efforts.

Evolutionary Diversity as a Source for Anticancer Molecules

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Author :
Publisher : Academic Press
ISBN 13 : 0128216980
Total Pages : 392 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Evolutionary Diversity as a Source for Anticancer Molecules by : Akhileshwar Kumar Srivastava

Download or read book Evolutionary Diversity as a Source for Anticancer Molecules written by Akhileshwar Kumar Srivastava and published by Academic Press. This book was released on 2020-09-21 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural productsderived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients.This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedicalfield interested in understanding more about natural products with anticancer potential. Discusses the application of natural products in place of conventional drugs to minimize the side effects in cancer treatment Explains the relation between evolutionary mechanisms and climate change for production of secondary metabolites

Natural Products in Chemical Biology

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118101170
Total Pages : 437 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Natural Products in Chemical Biology by : Natanya Civjan

Download or read book Natural Products in Chemical Biology written by Natanya Civjan and published by John Wiley & Sons. This book was released on 2012-07-03 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on the award winning Wiley Encyclopedia of Chemical Biology, this book provides a general overview of the unique features of the small molecules referred to as "natural products", explores how this traditionally organic chemistry-based field was transformed by insights from genetics and biochemistry, and highlights some promising future directions. The book begins by introducing natural products from different origins, moves on to presenting and discussing biosynthesis of various classes of natural products, and then looks at natural products as models and the possibilities of using them in medicine.