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Author : Massimo Vitale
Publisher : Frontiers Media SA
ISBN 13 : 2889636127
Total Pages : 256 pages
Book Rating : 4.8/5 (896 download)
Download or read book Natural Killer Cells in Tissue Compartments written by Massimo Vitale and published by Frontiers Media SA. This book was released on 2020-03-24 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Michael T. Lotze
Publisher : Academic Press
ISBN 13 : 9780080919294
Total Pages : 660 pages
Book Rating : 4.9/5 (192 download)
Download or read book Natural Killer Cells written by Michael T. Lotze and published by Academic Press. This book was released on 2009-11-12 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners Includes figures, histologic sections, and illustrations of the ontogeny of NK cells
Author : Emanuela Marcenaro
Publisher : Frontiers Media SA
ISBN 13 : 2889453502
Total Pages : 245 pages
Book Rating : 4.8/5 (894 download)
Download or read book NK Cell Subsets in Health and Disease: New Developments written by Emanuela Marcenaro and published by Frontiers Media SA. This book was released on 2017-11-29 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
Author : Lisa H. Butterfield, PhD
Publisher : Springer Publishing Company
ISBN 13 : 0826137431
Total Pages : 1339 pages
Book Rating : 4.8/5 (261 download)
Download or read book Cancer Immunotherapy Principles and Practice, Second Edition written by Lisa H. Butterfield, PhD and published by Springer Publishing Company. This book was released on 2021-08-25 with total page 1339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated to reflect major advances in the field of immuno-oncology, this second edition of Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer. The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, Second Edition is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field. Key Features: Offers key insights and perspectives on cancer immunology and immunotherapy treatments from renowned experts in the field Covers the basic principles and science behind cancer immunotherapy and tumor immunology Includes treatment strategies for a vast array of available immunotherapy classes and agents, such as cytokine therapies, oncolytic viruses, cancer vaccines, CAR T therapies, and combination immunotherapies Provides essential information on FDA-approved immunotherapies, including clinical management and outcome data related to response rates, risks, and toxicities Discusses special considerations for immunotherapy in the context of specific disease settings, including skin cancers, genitourinary cancers, gastrointestinal cancers, hepatocellular carcinomas, gynecologic malignancies, breast cancers, lung cancers, head and neck cancers, brain tumors, sarcomas, pediatric cancers, and treatments combined with radiation therapy Clarifies the complex regulatory aspects behind the development and approval of immunotherapy drugs
Author :
Publisher :
ISBN 13 :
Total Pages : 1422 pages
Book Rating : 4.:/5 (319 download)
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Raffaele Badolato
Publisher : Springer Science & Business Media
ISBN 13 : 376437442X
Total Pages : 249 pages
Book Rating : 4.7/5 (643 download)
Download or read book Lymphocyte Trafficking in Health and Disease written by Raffaele Badolato and published by Springer Science & Business Media. This book was released on 2006-09-05 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the description of the role of chemokines in immune response and underlines potential targets of therapeutical intervention. It offers a series of international contributions of the most challenging aspects of lymphocyte migration in homeostasis and in disease, and has a special focus on diseases and targets of therapeutical intervention. The book will interest researchers and clinicians from inflammation research.
Author : Anna Ohradanova-Repic
Publisher : Frontiers Media SA
ISBN 13 : 2889637212
Total Pages : 224 pages
Book Rating : 4.8/5 (896 download)
Download or read book Role of Metabolism in Regulating Immune Cell Fate Decisions written by Anna Ohradanova-Repic and published by Frontiers Media SA. This book was released on 2020-05-26 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Author : The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety
Publisher : Springer Science & Business Media
ISBN 13 : 9780898388435
Total Pages : 538 pages
Book Rating : 4.3/5 (884 download)
Download or read book Immunotoxicology written by The Commission of the European Communities & UNEP, ILO, WHO International Programme on Chemical Safety and published by Springer Science & Business Media. This book was released on 1987-02-28 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: IX The International Seminar on the Immunological System as a Target for Toxic Damage was held at The Commission of the European Communities (CEC) in Luxembourg on 6-9 November 1984. It was organized by the CEC and the International Programme on Chemical Safety of UNEP/ILO/WHO with the support of the u. S. Environmental Protection Agency and the National Institute of Environmental Health Sciences - USA and with the participation of the International Society of Immunophar macology. These bodies are actively concerned with the scientific and applied aspects of immunotoxicology. The Seminar consisted of thirty-four invited papers and three major panel discussions covering current and future test strategies for the screening of immunotoxic substances, hypersensitivity and the health implications of immunotoxico logical problems. It was attended by more than 200 scien tists from 27 countries representing all the Member states of the European Economic Community and the six Regions of the World Health Organization. These scientists represented many different disciplines and interests. The Seminar's principal objectives were: a review of recent advances in knowledge concerning the structure, function and dysfunction of the immunological system; - a review of the effects of xenobiotics on the immune system in animals and humans; an examination of the human health implications of immunotoxicity; discussion and critical analysis of the procedures for the assessment of immunological damage, a discussion of needs for the further development of laboratory and epidemiological methods and their validation, and a consideration of current test strategies.
Author : Ira Wolinsky
Publisher : CRC Press
ISBN 13 : 1000722163
Total Pages : 708 pages
Book Rating : 4.0/5 (7 download)
Download or read book Nutrition in Exercise and Sport, Third Edition written by Ira Wolinsky and published by CRC Press. This book was released on 2022-01-28 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of Nutrition in Exercise and Sport has been updated and expanded to include the latest developments in the field. This third edition of a bestseller among sports nutrition and health professionals now fully discusses the role of exercise and nutrition in both wellness and in disease prevention. In addition, new chapters on the history of sports nutrition, antioxidants, vegetarianism, the young athlete, the older athlete, the diabetic athlete, the physically disabled athlete, sports specific nutrient requirements, and body composition changes have been added. Top sports nutrition practitioners and exercise scientists have contributed chapters that provide practical nutritional guidelines for those engaged in various types of physical performance. This book is a one-volume library on sports nutrition for research scientists in applied sports nutrition, dietitians, exercise physiologists, sports medicine physicians, coaches, trainers, athletes, and nutritionists. The first two editions of this book have been widely used in sports nutrition courses. Nutrition in Exercise and Sport is the standard in the field.
Author : Srinivas S. Somanchi
Publisher : Humana Press
ISBN 13 : 9781493936823
Total Pages : 365 pages
Book Rating : 4.9/5 (368 download)
Download or read book Natural Killer Cells written by Srinivas S. Somanchi and published by Humana Press. This book was released on 2016-05-13 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains collection of Natural Killer Cell methodologies relevant for both basic and translational research. These methodologies present new developments in the natural killer (NK) cell field, such as understanding the influence of NK cells metabolism on its function, identifying complexity of NK cell subsets through mass cytometry, and determining the emergence of memory NK cells in murine model of MCMV infection. Methods that study NK cell migration and cytotoxicity through endpoint analysis or live single cell imaging are also discussed. Chapters also describe methods pertaining to translational application of NK cells, such as ex vivo expansion of NK cells on K562 cell lines genetically modified to express either membrane bound IL-15 or membrane bound IL-21, large scale NK cell culture, current techniques for engineering NK cells to express chimeric antigen receptors or chemokine receptors using retroviral vectors, electroporation of mRNA, and the natural phenomenon of trogocytosis. Written in the highly successful Methods in Molecular Biology series format, these chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, Natural Killer Cells: Methods and Protocols is a valuable resource for researchers who not only want to understand mechanisms that govern NK cell behavior and diversity, but also for those who want to understand how to systematically evaluate NK cells for adoptive immunotherapy applications.
Author : Leslie P. Gartner
Publisher : Elsevier Health Sciences
ISBN 13 : 0323390684
Total Pages : 672 pages
Book Rating : 4.3/5 (233 download)
Download or read book Textbook of Histology E-Book written by Leslie P. Gartner and published by Elsevier Health Sciences. This book was released on 2015-11-20 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated to reflect all of the latest concepts and advances in the field, this concise, extensively illustrated text presents the basic science and clinical application of cellular and molecular biology. Functioning as a combined text and atlas, it is essentially two books for the price of one providing a comprehensive, visually engaging histology education from the ground up. Illustrations, tables, chapter summaries and multiple choice questions facilitate comprehension of concepts, and clinical correlations underscore the practical relevance of the material. Superb illustrations—including photomicrographs, electron micrographs, schematic diagrams and drawings—provide a visual grasp and easier retention of difficult concepts. Clinical correlations throughout the text demonstrate clinical applications and reinforce the idea that histology is pertinent not only to pathology and physiology, but in fact comprises one of the essential bases of clinical practice. New! "Pathological Considerations" section at the end of each chapter. Helpful tables provide an at-a-glance summary statement of key points. Bolded key terms, bulleted lists and chapter summaries emphasize the "need to know" information in every chapter. A combination of USMLE-style questions and image based questions in each chapter.
Author : Leslie P. Gartner
Publisher : Elsevier Health Sciences
ISBN 13 : 0323672744
Total Pages : 668 pages
Book Rating : 4.3/5 (236 download)
Download or read book Textbook of Histology written by Leslie P. Gartner and published by Elsevier Health Sciences. This book was released on 2020-01-23 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Histology, 5th Edition, brings you up to date with all that’s new in the field, while providing a solid foundation in the basic science and clinical application of cellular and molecular biology. Concise and highly illustrated, it functions as both a text and a histology laboratory guide and remains the only histology textbook that includes laboratory exercises for nearly every chapter. Numerous new clinical observations illustrate the importance of histology to clinical practice. More than 170 photomicrographs as well as new drawings, and histology laboratory instructions in most chapters have been added to this edition. Greatly revised content includes new findings in cellular and molecular biology such as the newly discovered endoplasmic reticulum-shaping proteins, the abundance of stem cells in adipose tissue, the phases of Alzheimer’s disease and the role of the newly discovered glymphatic system in slowing the progression of the disease, and developments in the microbiome. More quick-reference tables have been added to summarize information discussed in the text. PowerPointTM presentations, bolded key terms, bulleted lists, and chapter summaries highlight "need to know" information and facilitate comprehension A combination of USMLE-style questions and image-based questions are found in each chapter of the digital edition
Author : Michael T. Lotze
Publisher : Elsevier
ISBN 13 : 0080479332
Total Pages : 759 pages
Book Rating : 4.0/5 (84 download)
Download or read book Measuring Immunity written by Michael T. Lotze and published by Elsevier. This book was released on 2011-05-04 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity* Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied
Author : Steven D. Holladay
Publisher : CRC Press
ISBN 13 : 9781420024036
Total Pages : 386 pages
Book Rating : 4.0/5 (24 download)
Download or read book Developmental Immunotoxicology written by Steven D. Holladay and published by CRC Press. This book was released on 2004-11-15 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite rapidly increasing interest in developmental immunotoxicology, there is not yet a textbook focused on this hot area of research. Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment. This text describes different models used to study developmental immunotoxicology and examples of specific developmental immunotoxic agents, including therapeutics. The text concludes with several chapters that describe the role of neuroimmune interactions as they relate to developmental immunotoxicology. Using a didactic approach, Developmental Immunotoxicology provides an explanatory overview of this cutting-edge field for toxicologists, immunologists, and developmental biologists. It provides a lucid account of this area of research-proposing answers to some questions and stimulating debate on those questions yet to be addressed by the research community.
Author : Guido Ferrari
Publisher : Frontiers Media SA
ISBN 13 : 2889638901
Total Pages : 273 pages
Book Rating : 4.8/5 (896 download)
Download or read book Fc-Mediated Antibody Functions and Fc-Receptor Polymorphism written by Guido Ferrari and published by Frontiers Media SA. This book was released on 2020-07-28 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Chaim Putterman
Publisher : Academic Press
ISBN 13 : 0128033703
Total Pages : 192 pages
Book Rating : 4.1/5 (28 download)
Download or read book Structural Biology in Immunology written by Chaim Putterman and published by Academic Press. This book was released on 2018-05-14 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Biology in Immunology, Structure/Function of Novel Molecules of Immunologic Importance delivers important information on the structure and functional relationships in novel molecules of immunologic interest. Due to an increasingly sophisticated understanding of the immune system, the approach to the treatment of many immune-mediated diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease has been dramatically altered. Furthermore, there is an increasing awareness of the critical role of the immune system in cancer biology. The improved central structure function relationships presented in this book will further enhance our ability to understand what defects in normal individuals can lead to disease. Describes novel/recently discovered immunomodulatory proteins, including antibodies and co-stimulatory or co-inhibitory molecules Emphasizes new biologic and small molecule drug design through the exploration of structure-function relationship Features a collaborative editorial effort, involving clinical immunologists and structural biologists Provides useful and practical insights on developing the necessary links between basic science and clinical therapy in immunology Gives interested parties a bridge to learn about computer modeling and structure based design principles
