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Natriuretic Peptides
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Book Synopsis Natriuretic Peptides by : Aldo Clerico
Download or read book Natriuretic Peptides written by Aldo Clerico and published by Springer Science & Business Media. This book was released on 2007-03-14 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern cardiovascular science has produced a revolutionary new idea: the heart acts not merely as a pump, but as a "gland", that is as a regulator of circulatory homeostasis and salt-water balance. This book combines the classical heamodynamic view with the new neuro-hormonal paradigm, in all its potential clinical implications. The book will interest physiologists and clinicians involved in the study of the cardiovascular system and care of heart patients.
Book Synopsis Comprehensive Hypertension E-Book by : Gregory Y. H. Lip
Download or read book Comprehensive Hypertension E-Book written by Gregory Y. H. Lip and published by Elsevier Health Sciences. This book was released on 2007-06-28 with total page 1247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is today's most in-depth reference for any cardiologist, internist, or nephrologist interested in hypertension. Drawing from international experience in cardiology, physiology, and nephrology, Drs. Lip and Hall have assembled a group of section editors and contributors second to none. You'll find the long-term effects of primary and secondary hypertension and a lengthy section on hypertensions for special populations featured prominently. Prevention and treatment of hypertension are covered in detail, from lifestyle and diet issues to drug choice and delivery, and the section on comparison of guidelines is unique to this book. Find comprehensive coverage of hypertension including pathogenesis, prevention, and treatment all in one practical volume. See the complete systemic problems of hypertension at a glance with detailed, full-color illustrations of cellular and clinical manifestations. Simplify navigating the complexities of hypertension using algorithms for clinical exam and diagnosis. Get specific insight into prevention and treatment of hypertension in special populations. Go global with a comprehensive section on worldwide guidelines and the application of clinical material to local standards of practice.
Book Synopsis Innovative Medicine by : Kazuwa Nakao
Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Author :Harald H. H. W. Schmidt Publisher :Springer Science & Business Media ISBN 13 :3540689648 Total Pages :581 pages Book Rating :4.5/5 (46 download)
Book Synopsis cGMP: Generators, Effectors and Therapeutic Implications by : Harald H. H. W. Schmidt
Download or read book cGMP: Generators, Effectors and Therapeutic Implications written by Harald H. H. W. Schmidt and published by Springer Science & Business Media. This book was released on 2008-12-17 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.
Book Synopsis Natriuretic Peptides in Health and Disease by : Willis K. Samson
Download or read book Natriuretic Peptides in Health and Disease written by Willis K. Samson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, state-of-the-art review of the biochemistry, molecular and cellular biology, pharmacology, physiology, and pathology of natriuretic peptides. Written by the foremost researchers in the field, the reviews range from describing the actions of these peptides on the kidney, adrenal gland, vasculature, and brain, to their effects on immune regulation, reproduction, and cell growth. Special attention is given to the potential involvement of these hormones in clinical pathology and to their possible therapeutic use. Especially enlightening is the first-time review of molecular understanding of key cellular signaling pathways and of the importance of the vascular smooth muscle-endothelial interface.
Book Synopsis A Compendium of Natriuretic Peptides: Their Structures, Receptors, Physiologic Functions, Therapeutic Applications etc. by : Dr. Hakim. K. Saboowala
Download or read book A Compendium of Natriuretic Peptides: Their Structures, Receptors, Physiologic Functions, Therapeutic Applications etc. written by Dr. Hakim. K. Saboowala and published by Dr.Hakim Saboowala. This book was released on 2020-10-21 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Compendium of Natriuretic Peptides: Their Structures, Receptors, Physiologic Functions, Therapeutic Applications etc. Definition of Natriuretic peptide: One of the peptides that causes natriuresis, the excretion of an excessively large amount of sodium in the urine. Natriuretic peptides are a family of three structurally related hormone/paracrine factors. Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are secreted from the cardiac atria and ventricles, respectively. 1. ANP signals in an endocrine and paracrine manner to decrease blood pressure and cardiac hypertrophy. 2. BNP acts locally to reduce ventricular fibrosis. 3. C-type natriuretic peptide (CNP) primarily stimulates long bone growth but likely serves unappreciated functions as well. ANP and BNP activate the transmembrane guanylyl cyclase, natriuretic peptide receptor-A (NPR-A). CNP activates a related cyclase, natriuretic peptide receptor-B (NPR-B). Both receptors catalyze the synthesis of cGMP, which mediates most known effects of natriuretic peptides. A third natriuretic peptide receptor, natriuretic peptide receptor-C (NPR-C), clears natriuretic peptides from the circulation through receptor-mediated internalization and degradation. However, a signaling function for the receptor has been suggested as well. A few mutations in these proteins have been reported in humans. Synthetic analogs of ANP (anaritide and carperitide) and BNP (nesiritide) have been investigated as potential therapies for the treatment of decompensated heart failure and other diseases. · Anaritide and nesiritide are approved for use in acute decompensated heart failure. New clinical trials are examining the effect of nesiritide and novel peptides, like CD-NP, on these critical parameters. An attempt has been made in this Booklet to discus the History, Structure, Function, and Clinical Applications of Natriuretic peptides and their Receptors etc. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Book Synopsis Natriuretic Peptides: Advances in Research and Application: 2011 Edition by :
Download or read book Natriuretic Peptides: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natriuretic Peptides: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Natriuretic Peptides in a concise format. The editors have built Natriuretic Peptides: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Natriuretic Peptides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Natriuretic Peptides: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides by : Speranza Rubattu
Download or read book Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides written by Speranza Rubattu and published by MDPI. This book was released on 2019-10-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: The natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and kidney functions. NPs have also been implicated in the pathogenesis of several cardiovascular diseases (CVDs), including hypertension, atherosclerosis, heart failure, and stroke. A fine comprehension of the molecular mechanisms dependent from NPs and underlying the promotion of cardiovascular damage has contributed to improve our understanding of the molecular basis of all major CVDs. Finally, the opportunity to target NPs in order to develop new therapeutic tools for a better treatment of CVDs has been developed over the years. The current Special Issue of the Journal covers all major aspects of the molecular implications of NPs in physiology and pathology of the cardiovascular system, including NP-based therapeutic approaches.
Book Synopsis The Control Of Lipid Metabolism by : Biochemical Society Symposium
Download or read book The Control Of Lipid Metabolism written by Biochemical Society Symposium and published by Legare Street Press. This book was released on 2022-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Book Synopsis Natriuretic Peptides—Advances in Research and Application: 2013 Edition by :
Download or read book Natriuretic Peptides—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natriuretic Peptides—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Brain Natriuretic Peptide in a concise format. The editors have built Natriuretic Peptides—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Brain Natriuretic Peptide in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Natriuretic Peptides—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Emerging Applications, Perspectives, and Discoveries in Cardiovascular Research by : Malhotra, Ashim
Download or read book Emerging Applications, Perspectives, and Discoveries in Cardiovascular Research written by Malhotra, Ashim and published by IGI Global. This book was released on 2017-01-25 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific developments in recent years have led to significant strides and advancements within the medical field. By integrating these findings into medical practice, optimal healthcare can be delivered to the public. Emerging Applications, Perspectives, and Discoveries in Cardiovascular Research is a comprehensive reference source for the latest academic material on the exploration of cardiovascular diseases and provides an interdisciplinary examination of novel developments and applications for cardiovascular sciences. Highlighting a range of diverse topics, such as pharmacology, pathophysiology, and alternative medicine, this book is ideally designed for researchers, professionals, practitioners, graduate students, and academics interested in the latest medical advancements.
Book Synopsis The Natriuretic Hormones by : Harvey Craig Gonick
Download or read book The Natriuretic Hormones written by Harvey Craig Gonick and published by Frontiers Media SA. This book was released on 2015-11-24 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: The title follows from the original demonstration by Dr. Hugh de Wardener in 1961 that a humoral agent is produced after extracellular volume expansion which results in a vigorous diuresis and natriuresis. Thus the name of "natriuretic hormone" was coined. In the years that followed several investigators pursued the search for the hormone. What resulted, however, was the discovery of several hormones with different characteristics, all of which were natriuretic. Initially it was found that the hormone was similar in action to ouabain or digoxin, hence the appelation of ouabain-like or digoxin-like. The hormone was found to be an inhibitor of Na-K-ATPase, which would fit with it being a cardiotonic steroid. On the other hand, neither ouabain or digoxin migrated on Sephadex gel filtration in the same locus as the hormone. Other investigators claim to have identified the hormone-initially as a vanadium-diascorbate, later as bufadienolides such as marinobufagenin, yet later as a macrocylic derivative of inorganic carbon suboxide with a molecular weight of 408 Da. Some support for the latter finding was derived from an earlier report that a semi-purified Sephadex-derived compound was found to have a molecular weight of about 12,000 Da but the active compound, when split from its carrier protein, had a molecular weight of exactly 408 Da. This compound had not been further identified. As further development was the demonstration by Bricker and colleagues that a natriuretic substance could be purified from uremic urine. This turned out to be a xathurenic acid derivative. Meanwhile the focus began to turn to natriuretic peptides derived from heart (ANF and BNP). These peptides have a shorter duration of action than the cardiotonic steroid-like hormone and ANF has proved to be most useful as a measure of heart failure. It should also be stressed that marinobufagenin, like ANF, is elevated in congestive heart failure, whereas the steroid-like hormone is depressed or absent in this state. This review will attempt to describe and contrast the properties of each of the proposed natriuretic hormones, including their locus on Sephadex separation, potency, duration of action, chemical structure (if known), behavior in hypertension, renal failure, heart failure, and brain disease. As most recent work has focussed on marinobufagenin, this hormone will be brought up to date by investigators in the field.
Book Synopsis Cardiac Biomarkers by : Alan S Maisel
Download or read book Cardiac Biomarkers written by Alan S Maisel and published by JP Medical Ltd. This book was released on 2012 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac Biomarkers describes the most recent developments in the field of biomarkers, providing best practice and current guidelines. It also discusses how these guidelines may alter in the future. With contributions from internationally-based clinicians and scientists, this book includes almost 100 detailed images and illustrations. Topics covered include: Markers of Cardiac Arrest, Markers of Cardiac Ischemia, Natriuretic Peptides for Heart Failure, Biomarkers in Cardio Renal Disease and Future Developments.
Book Synopsis Natriuretic Peptides—Advances in Research and Application: 2012 Edition by :
Download or read book Natriuretic Peptides—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natriuretic Peptides—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Natriuretic Peptides in a concise format. The editors have built Natriuretic Peptides—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Natriuretic Peptides in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Natriuretic Peptides—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Pathophysiology and Pharmacotherapy of Cardiovascular Disease by : Gowraganahalli Jagadeesh
Download or read book Pathophysiology and Pharmacotherapy of Cardiovascular Disease written by Gowraganahalli Jagadeesh and published by Springer. This book was released on 2015-05-06 with total page 1323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.
Book Synopsis Cellular Peptide Hormone Synthesis and Secretory Pathways by : Jens F. Rehfeld
Download or read book Cellular Peptide Hormone Synthesis and Secretory Pathways written by Jens F. Rehfeld and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones – including the old master hormone insulin – represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.
Book Synopsis Heart Failure in the Child and Young Adult by : John L Jefferies
Download or read book Heart Failure in the Child and Young Adult written by John L Jefferies and published by Academic Press. This book was released on 2017-12-05 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine. Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation Combines cutting-edge research with current guidelines from the field
