Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases

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Publisher : Academic Press
ISBN 13 : 0128014717
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases by : Mahendra Rai

Download or read book Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases written by Mahendra Rai and published by Academic Press. This book was released on 2015-05-23 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Nanotechnology for Infectious Diseases

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Publisher : Springer Nature
ISBN 13 : 9811691908
Total Pages : 638 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Nanotechnology for Infectious Diseases by : Saif Hameed

Download or read book Nanotechnology for Infectious Diseases written by Saif Hameed and published by Springer Nature. This book was released on 2022-04-13 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to cover the applications of nanotechnology against human infectious diseases. The chapters of the book discuss the role of nanotechnology in the efficient diagnosis and treatment of these diseases. It explicitly provides an overview of nanodiagnostics for infectious diseases from nanoparticles-based, nanodevice-based, and point-of-care platforms. The book also covers the state-of-the-art review of recent progress in biomimetic and bioengineered nanotherapies to treat infectious diseases. It also presents a nano carrier-based CRISPR/Cas9 delivery system for gene editing and its applications for developing interventional approaches against communicable diseases. Further, it reviews the recent developments in nanotechnology to engineer nanoparticles with desired physicochemical properties as a line of defense against multi-drug resistance micro-organisms. Cutting across the disciplines, this book serves as a guide for researchers in biotechnology, parasitology, and nanotechnology.

Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases

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Author :
Publisher : William Andrew
ISBN 13 : 0323264506
Total Pages : 408 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases by : Narenda Kumar

Download or read book Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases written by Narenda Kumar and published by William Andrew. This book was released on 2013-12-05 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases takes a scientific approach to nanotechnology and nanomaterials applications in medicine, while also explaining the core biological principles for an audience of biomedical engineers, materials scientists, pharmacologists, and medical diagnostic technicians. The book is structured by major disease groups, offering a practical, application-based focus for scientists, engineers, and clinicians alike. The spectrum of medical applications is explored, from diagnostics and imaging to drug delivery, monitoring, therapies, and disease prevention. It also focuses specifically on the synthesis of nanomaterials and their potential health risks (particularly toxicity). Nanomedicine — the application of nanomaterials and devices for addressing medical problems — has demonstrated great potential for enabling improved diagnosis, treatment, and monitoring of many serious illnesses, including cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory and infectious diseases. Gain an understanding of how nanotechnologies and nanomaterials can be deployed in the fight against the major life-threatening diseases: cancer, neurological disorders (including Alzheimer's and Parkinson's), cardiovascular diseases, and HIV/AIDS Discover the latest developments in nanomedicine, from therapies and drug delivery to diagnostics and disease prevention The authors cover the health risks of nanomaterials as well as their benefits, considering toxicity and potential carcinogens

The Clinical Nanomedicine Handbook

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Publisher : CRC Press
ISBN 13 : 1439834784
Total Pages : 368 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Clinical Nanomedicine Handbook by : Sara Brenner

Download or read book The Clinical Nanomedicine Handbook written by Sara Brenner and published by CRC Press. This book was released on 2013-12-13 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.

Smart Nanomaterials for Infectious Diseases

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Publisher : Royal Society of Chemistry
ISBN 13 : 183767082X
Total Pages : 435 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Smart Nanomaterials for Infectious Diseases by : Suvardhan Kanchi

Download or read book Smart Nanomaterials for Infectious Diseases written by Suvardhan Kanchi and published by Royal Society of Chemistry. This book was released on 2024-03-25 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on how sustainable nanomaterials can help with various aspects of infectious diseases, including prevention, diagnosis, and treatment, as well as the characteristics that materials should possess in order to enter clinical trials.

Infectious Diseases and Nanomedicine III

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Publisher : Springer
ISBN 13 : 9811075727
Total Pages : 116 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Infectious Diseases and Nanomedicine III by : Rameshwar Adhikari

Download or read book Infectious Diseases and Nanomedicine III written by Rameshwar Adhikari and published by Springer. This book was released on 2018-05-21 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers selected peer-reviewed papers presented at the Second International Conference on Infectious Diseases and Nanomedicine (ICIDN), held in Kathmandu, Nepal on December 15–18, 2015. It also includes invited papers from the leading experts in the related fields. The book highlights the importance of “Interdisciplinary Collaborative Research for Innovation in the Biomedical Sciences,” the motto of the ICIDN conference. In particular, it addresses interdisciplinary scientific approaches for systematic understanding of the biology of major human infectious diseases and their treatment regimes by applying the tools and techniques of nanotechnology. It also provides cutting-edge information on infectious diseases and nanomedicine, focusing on various aspects of emerging infectious diseases: cellular and molecular microbiology; epidemiology and infectious disease surveillance; antimicrobials, vaccines and alternatives; drug design, drug delivery and tissue engineering; nanomaterials and biomedical materials.

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

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Publisher : Academic Press
ISBN 13 : 0323914691
Total Pages : 414 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nanotheranostics for Treatment and Diagnosis of Infectious Diseases by : Keerti Jain

Download or read book Nanotheranostics for Treatment and Diagnosis of Infectious Diseases written by Keerti Jain and published by Academic Press. This book was released on 2022-05-21 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases. Compiles the latest information on the technological advancements made in the field of nanotechnology for applications in therapeutics Prepares researchers to get ready to fight any emergency which may arise due to the advent of infectious diseases Focuses on the theranostic applications of nanomaterials in infectious diseases Compiles all relevant information to help scientists, researchers and students in understanding the role of nanomaterials and how they could be explored for therapeutic and diagnostic applications

Nanomedicines for the Prevention and Treatment of Infectious Diseases

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Author :
Publisher : Springer Nature
ISBN 13 : 3031390202
Total Pages : 415 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Nanomedicines for the Prevention and Treatment of Infectious Diseases by : Vandana B. Patravale

Download or read book Nanomedicines for the Prevention and Treatment of Infectious Diseases written by Vandana B. Patravale and published by Springer Nature. This book was released on 2023-12-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: The COVID-19 pandemic has altered the world and reiterated the perpetual need for the development of effective strategies for the prevention and treatment of infectious diseases. While globally prevalent infectious diseases receive extensive attention in terms of drug development and delivery, the neglected and/or emerging infectious diseases that affect developing countries are often overlooked. Additionally, the therapeutic efficacy of existing anti-infective agents is often limited due to sub-optimal biopharmaceutical properties, sub-therapeutic levels of the drugs at the infection site due to various physiological barriers, the expulsion of the drug by efflux transporters, and the emergence of drug-resistant strains. From the commercialization of AmBisome® to the emergency authorization of mRNA-based vaccines, nanotechnology has played a vital role in the prevention and treatment of infectious diseases. More importantly, nanotechnology has enabled the effective utilization of existing armamentarium against infectious diseases leading to improved therapeutic outcomes with a concomitant reduction in the side effects associated with anti-infective agents. In particular, nanotechnology can bring about a paradigm shift in the management of neglected and emerging infectious diseases and may compensate for the lack of drug discovery efforts. While there are several books dedicated to pharmaceutical and/or biomedical applications of nanotechnology or nanotechnology for cancer therapy a comprehensive book focusing on the prevention and/or treatment of viral, bacterial, fungal, and parasitic infections is not available. This book addresses an unmet need in pharmaceutical and medical education. This book provides a comprehensive and up-to-date overview of the latest advancements in nanomedicine, which show great potential for preventing and treating infectious diseases. Covering a wide range of topics, it explores various formulation strategies for combating microbial, fungal, parasitic, and viral infections. The book emphasizes the advantages of nano-scale vaccines over traditional ones and discusses their production. It also examines feasible treatment approaches for diseases like malaria, trypanosomiasis, candidiasis, Hepatitis B, HIV, and the ongoing COVID-19 pandemic. Additionally, it highlights the role of nano-adjuvants in vaccine development, as well as the use of peptide antibiotics and pulmonary delivery of drugs, which open up new possibilities in fighting infectious diseases. Furthermore, the book explores the critical role of nanomedicine in addressing veterinary parasitic infections. The emergence of nanotechnology has led to novel strategies for diagnosing, treating, and preventing parasitic infections in animals. In summary, this book offers a comprehensive description of clinically viable and investigational nanotechnology-enabled medicines (nanomedicines) for the prevention and treatment of globally prevalent, neglected, and emerging infectious diseases.

Infectious Diseases and Nanomedicine I

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Publisher : Springer Science & Business Media
ISBN 13 : 8132217772
Total Pages : 119 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Infectious Diseases and Nanomedicine I by : Rameshwar Adhikari

Download or read book Infectious Diseases and Nanomedicine I written by Rameshwar Adhikari and published by Springer Science & Business Media. This book was released on 2014-03-11 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a first volume which presents collection of best papers presented in the First International Conference on Infectious Diseases and Nanomedicine held during Dec. 15-18, 2012 in Kathmandu, Nepal. The book focuses mainly on the topics: emerging infectious diseases; antimicrobial agents, vaccines and immunity; drug design, drug delivery and tissue engineering and nanomaterials and biomedical materials.

Nanomedicine

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Publisher : Academic Press
ISBN 13 : 0123918588
Total Pages : 475 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Nanomedicine by : Nejat Duzgunes

Download or read book Nanomedicine written by Nejat Duzgunes and published by Academic Press. This book was released on 2012-05-23 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Methods in Enzymology series comprehensively covers Infectious Diseases, Immunotheraphy, Gene Medicine, Diagnostics and Toxicology of Nanomedicine. With an international board of authors, this volume is split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine toxicity, and Diagnostic Nanomedicine. Comprehensively covers infectious diseases, immunotherapy, gene medicine, diagnostics, and toxicology of nanomedicine International board of authors Split into sections that cover subjects such as Nanomedicines in Immunotherapy, Nanomedicine Toxicity, and Diagnostic Nanomedicine

Infectious Diseases and Nanomedicine II

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Publisher : Springer
ISBN 13 : 8132217748
Total Pages : 99 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Infectious Diseases and Nanomedicine II by : Rameshwar Adhikari

Download or read book Infectious Diseases and Nanomedicine II written by Rameshwar Adhikari and published by Springer. This book was released on 2014-07-08 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses the interdisciplinary scientific approach for the systemic understanding of connections between major human diseases and their treatment regime by applying the tools and techniques of nanotechnology. It also highlights the interdisciplinary collaborative researches for innovation in Biomedical Sciences. The book is a second volume which presents collection of best papers presented in the First International Conference on Infectious Diseases and Nanomedicine held during Dec. 15-18, 2012 in Kathmandu, Nepal. The book focuses mainly on the topics: emerging infectious diseases; antimicrobial agents, vaccines and immunity; drug design, drug delivery and tissue engineering and nanomaterials and biomedical materials.

The Use of Nanoparticles in the Diagnosis and Therapy of Infectious Disease in Animals

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832531172
Total Pages : 63 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The Use of Nanoparticles in the Diagnosis and Therapy of Infectious Disease in Animals by : Gerson Nakazato

Download or read book The Use of Nanoparticles in the Diagnosis and Therapy of Infectious Disease in Animals written by Gerson Nakazato and published by Frontiers Media SA. This book was released on 2023-09-28 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, nanoparticles have shown efficacy against antimicrobial activity, including several microorganisms and those that are multidrug-resistant. Nanosensors represent an advance in the diagnosis of infectious diseases, particularly those with zoonotic risk. Different strategies using nanoparticles have been examined for both diagnosis and treatment of these diseases, as well as prevention. The optimization of detection methods and antimicrobial activity is a challenge in microbiology. Advances using nanotechnology are an emerging alternative to solve some problems in the diagnosis and therapy of veterinary infectious diseases. There are implications for the application of nanoparticles to shape interactions with the microorganism itself, as well as influence the bioavailability, biocompatibility, and biodegradation of the system with low host toxicity. The time of detection and its ability to target pathogens can be improved with nanotechnology.

Nanomedicine in Health and Disease

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Publisher : CRC Press
ISBN 13 : 1578087252
Total Pages : 454 pages
Book Rating : 4.5/5 (78 download)

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Book Synopsis Nanomedicine in Health and Disease by : Ross J. Hunter

Download or read book Nanomedicine in Health and Disease written by Ross J. Hunter and published by CRC Press. This book was released on 2011-08-10 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nanosciences are a rapidly expanding field of research with a wide applicability to all areas of health and disease prevention. This book, covers the regulation of nanomedicine, nanotubes, topical applications of nanoparticles, nanocrystals, antioxidant nanoparticles, lipid nanocapsules, nanotheragnostic colloids, nanotechnology in the control of infectious disease, virus-based nanoparticles and the safety of nanoparticles. It also covers nanomedicine in relation to pulmonary drug delivery, the control of infectious disease, radiation protection, arthritis, cancer nanomedicine, blood diseases, neurodegenerative disorders, and tissue and implant engineering.

NanoBioMedicine

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Publisher : Springer Nature
ISBN 13 : 9813298987
Total Pages : 510 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis NanoBioMedicine by : Shailendra K. Saxena

Download or read book NanoBioMedicine written by Shailendra K. Saxena and published by Springer Nature. This book was released on 2020-02-03 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology.

Nanotechnology Based Approaches for Tuberculosis Treatment

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Publisher : Academic Press
ISBN 13 : 0128226110
Total Pages : 284 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Nanotechnology Based Approaches for Tuberculosis Treatment by : Prashant Kesharwani

Download or read book Nanotechnology Based Approaches for Tuberculosis Treatment written by Prashant Kesharwani and published by Academic Press. This book was released on 2020-06-10 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

Nanobiotechnology in Diagnosis, Drug Delivery and Treatment

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119671779
Total Pages : 418 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Nanobiotechnology in Diagnosis, Drug Delivery and Treatment by : Mahendra Rai

Download or read book Nanobiotechnology in Diagnosis, Drug Delivery and Treatment written by Mahendra Rai and published by John Wiley & Sons. This book was released on 2020-12-02 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Nanotechnological Applications in Virology

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Publisher : Academic Press
ISBN 13 : 0323995977
Total Pages : 366 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nanotechnological Applications in Virology by : Mahendra Rai

Download or read book Nanotechnological Applications in Virology written by Mahendra Rai and published by Academic Press. This book was released on 2022-06-23 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnological Applications in Virology explores the use of nanoparticles-based technologies to fight against viruses, also discussing the use of nanoparticles in the preparation of nano masks and as sanitizing agents. The role of nanotechnology against HIV, Hepatitis, Influenza, Herpes, Ebola and Zika using rapid detection and diagnostic techniques is included, as is a brief description of SARS, MERS, the novel Coronavirus, and recent advancements in its treatment process. Other sections cover the formulation of novel nano-vaccines for the treatment and control of viral infections like HIV, Hepatitis and COVID-19. Included toxicological studies of nanoparticles provide readers with a brief overview on global scenarios regarding viral infections. Nanotechnology is the present age technology, with wide usage in different areas of medical science, including drug delivery, gene therapy, antimicrobials, biosensors and bio-labelling. Nanoparticles play a competent role as an anti-infection agent and thus act as efficient antiviral agents. Mitochondria as a Key Intracellular Target of Thallium Toxicity presents a new hypothesis that explains the decrease in antioxidant defense in thallium poisoning. In addition, the book proposes a new model for studying the transport of inorganic cations across the inner mitochondrial membrane. Readers will learn about the toxicity of thallium and its compounds, the toxicology of thallium, the toxic thallium effects on cells, and the effects of thallium on mitochondria. This book+J136 lists the pathways and mechanisms of thallium transport into cells and mitochondria. This toxicity has been analyzed at both the cellular and subcellular levels The increase in human contact with the toxic trace element thallium is associated with developments in industry, the release of this metal into the environment from various rocks, and the use of special isotope techniques for studying the vascular bed