Magnetic Resonance of Myelin, Myelination, and Myelin Disorders

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Publisher : Springer Science & Business Media
ISBN 13 : 366202568X
Total Pages : 734 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Magnetic Resonance of Myelin, Myelination, and Myelin Disorders by : Jacob Valk

Download or read book Magnetic Resonance of Myelin, Myelination, and Myelin Disorders written by Jacob Valk and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.

Netter's Atlas of Neuroscience

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323265111
Total Pages : 499 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Netter's Atlas of Neuroscience by : David L. Felten

Download or read book Netter's Atlas of Neuroscience written by David L. Felten and published by Elsevier Health Sciences. This book was released on 2015-11-30 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ideal for students of neuroscience and neuroanatomy, the new edition of Netter's Atlas of Neuroscience combines the didactic well-loved illustrations of Dr. Frank Netter with succinct text and clinical points, providing a highly visual, clinically oriented guide to the most important topics in this subject. The logically organized content presents neuroscience from three perspectives: an overview of the nervous system, regional neuroscience, and systemic neuroscience, enabling you to review complex neural structures and systems from different contexts. You may also be interested in: A companion set of flash cards, Netter's Neuroscience Flash Cards, 3rd Edition, to which the textbook is cross-referenced. Coverage of both regional and systemic neurosciences allows you to learn structure and function in different and important contexts. Combines the precision and beauty of Netter and Netter-style illustrations to highlight key neuroanatomical concepts and clinical correlations. Reflects the current understanding of the neural components and supportive tissue, regions, and systems of the brain, spinal cord, and periphery. Uniquely informative drawings provide a quick and memorable overview of anatomy, function, and clinical relevance. Succinct and useful format utilizes tables and short text to offer easily accessible "at-a-glance" information. Provides an overview of the basic features of the spinal cord, brain, and peripheral nervous system, the vasculature, meninges and cerebrospinal fluid, and basic development. Integrates the peripheral and central aspects of the nervous system. Bridges neuroanatomy and neurology through the use of correlative radiographs. Highlights cross-sectional brain stem anatomy and side-by-side comparisons of horizontal sections, CTs and MRIs. Features video of radiograph sequences and 3D reconstructions to enhance your understanding of the nervous system. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, 14 videos, and images from the book. Expanded coverage of cellular and molecular neuroscience provides essential guidance on signaling, transcription factors, stem cells, evoked potentials, neuronal and glial function, and a number of molecular breakthroughs for a better understanding of normal and pathologic conditions of the nervous system. Micrographs, radiologic imaging, and stained cross sections supplement illustrations for a comprehensive visual understanding. Increased clinical points -- from sleep disorders and inflammation in the CNS to the biology of seizures and the mechanisms of Alzheimer's -- offer concise insights that bridge basic neuroscience and clinical application.

Myelin

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Publisher : Oxford University Press
ISBN 13 : 0190686111
Total Pages : 333 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis Myelin by : Bernard Zalc

Download or read book Myelin written by Bernard Zalc and published by Oxford University Press. This book was released on 2018-08-22 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of myelin 425 million years ago marked a turning point in evolution. Consider for a moment the invention of insulated wire, which allows for the transmission of electrical current. Functioning in a similar way, the membrane surrounding nerve fibers, or myelin, enables the remarkable acceleration of nerve impulses. Surprisingly, myelin occupies nearly half the volume of the human brain and is critical for our intellectual and motor performance. Without myelin, our thoughts and our movements would suffer overwhelming delays. We owe our reflexes to myelin: it is what makes us brake when a child dashes out onto the road, or snatch away a hand absent-mindedly placed on a burning hot stove. When damaged, myelin can lead to irreversible disability, cognitive decline, and sensory impairments. The study of myelin's role in the conduction of nerve impulses has led to a better understanding of several diseases including multiple sclerosis, Guillain-Barre syndrome, Charcot disease (ALS), and Niemann-Pick disease.

Neuroproteomics

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Publisher : CRC Press
ISBN 13 : 1420076264
Total Pages : 356 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neuroproteomics by : Oscar Alzate

Download or read book Neuroproteomics written by Oscar Alzate and published by CRC Press. This book was released on 2009-10-26 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg

From Neurons to Neighborhoods

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Publisher : National Academies Press
ISBN 13 : 0309069882
Total Pages : 610 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis From Neurons to Neighborhoods by : National Research Council

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Handbook of Developmental Cognitive Neuroscience

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Publisher : MIT Press
ISBN 13 : 9780262140737
Total Pages : 734 pages
Book Rating : 4.1/5 (47 download)

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Book Synopsis Handbook of Developmental Cognitive Neuroscience by : Charles Alexander Nelson (III)

Download or read book Handbook of Developmental Cognitive Neuroscience written by Charles Alexander Nelson (III) and published by MIT Press. This book was released on 2001 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the new techniques that account for the progress and heightened activity in developmental cognitive science research.

The Biology of Oligodendrocytes

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Publisher : Cambridge University Press
ISBN 13 : 1139491717
Total Pages : pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The Biology of Oligodendrocytes by : Patricia Armati

Download or read book The Biology of Oligodendrocytes written by Patricia Armati and published by Cambridge University Press. This book was released on 2010-10-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.

Myelinated Fibers and Saltatory Conduction in the Shrimp

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Publisher : Springer Science & Business Media
ISBN 13 : 4431539247
Total Pages : 121 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Myelinated Fibers and Saltatory Conduction in the Shrimp by : Ke Xu

Download or read book Myelinated Fibers and Saltatory Conduction in the Shrimp written by Ke Xu and published by Springer Science & Business Media. This book was released on 2013-10-20 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1961, neurobiologists found that the conduction velocity of the nerve impulse in the giant nerve fiber of the Penaeus shrimp abdominal nerve cord was over 200 m/s, the highest speed of information transmission ever observed in the animal kingdom. The peculiar myelin sheath with its unique nodal structure and the electrical properties of the nerve fibers of the shrimp have continued to be investigated for a quarter of century and are now fully described in this book. The investigation dispels the commonly held belief that the fastest recorded impulse conduction is about 120 m/s in the thickest vertebrate myelinated nerve fibers. In the shrimp, researchers found a completely novel type of functional node in the giant fiber which they designated as the fenestration node. In portions of the myelinated fiber, the fenestration node furnished the sites of excitation. Also discovered was a new strategy for increasing impulse conduction in the shrimp. The book includes a section on the formation of the fenestration node and the discovery of a strategy that allows the shrimp to escape its predators by an action of the fastest velocity. The data presented in this volume on the myelin sheath of invertebrates present a new direction for this field and a rich source of information for neurobiologists worldwide.

Clinical MR Imaging

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Publisher : Springer Science & Business Media
ISBN 13 : 3540745041
Total Pages : 831 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Clinical MR Imaging by : Peter Reimer

Download or read book Clinical MR Imaging written by Peter Reimer and published by Springer Science & Business Media. This book was released on 2010-04-14 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) has become the leading cross-sectional imaging method in clinical practice. Continuous technical improvements have significantly broadened the scope of applications. At present, MR imaging is not only the most important diagnostic technique in neuroradiology and musculoskeletal radiology, but has also become an invaluable diagnostic tool for abdominal, pelvic, cardiac, breast and vascular imaging. This book offers practical guidelines for performing efficient and cost-effective MRI examinations in daily practice. The underlying idea is that, by adopting a practical protocol-based approach, the work-flow in a MRI unit can be streamlined and optimized.

Myelination and Demyelination

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Publisher : Springer Science & Business Media
ISBN 13 : 1461307775
Total Pages : 276 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Myelination and Demyelination by : Seung U. Kim

Download or read book Myelination and Demyelination written by Seung U. Kim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: In June 1987, neurobiologists, immunologists, molecular biologists, virologists and neurologists from several countries met in Vancouver to discuss recent advances of relevance to multiple sclerosis. The symposium was a part of the 22nd Canadian Congress of Neurological Sciences meeting and was sponsored by funds from the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada. The presentations covered five major topics: basic neurobiology, molecular biology, the role of viruses in demyelination, immune function and dysfunction in multiple sclerosis, and clinical magnetic resonance imaging studies. It was heartening to note that scientists from several different disciplines were working towards a common end-point: the understanding and treatment of multiple sclerosis. In this book, speakers at the symposium have each presented a chapter of their findings and discussions. In addition, some non-participants at the symposium have been invited to submit chapters in order to give this volume a more complete scope. It is hoped that the reader will find this book a useful reference for several subjects of interest to multiple sclerosis. In closing, I would like to thank the following for their help and support: the Multiple Sclerosis Society of Canada and the Medical Research Council of Canada for their financial support; the contributors of this book for their manuscripts; Dr. A. Eisen, Mrs. K. Eisen, Mrs. P. Bodnarchuk and Mrs. M. Kim for their efforts in planning and organizing the symposium; and Ms. Catherine Schikowski for her secretarial assistance. Seung U. Kim, M.D. Ph.D.

Neuroprotection in Alzheimer's Disease

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Publisher : Academic Press
ISBN 13 : 0128037121
Total Pages : 344 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuroprotection in Alzheimer's Disease by : Illana Gozes

Download or read book Neuroprotection in Alzheimer's Disease written by Illana Gozes and published by Academic Press. This book was released on 2016-12-30 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection in Alzheimer's Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer's disease will pave the path to better disease management and novel therapeutics. - Comprehensive reference detailing neuroprotection in Alzheimer's Disease, with details on nerve cell protection and new advances in disease management - Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development - Edited by one of the leading researchers in Alzheimer's Disease

Pediatric Brain and Spine

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Publisher : Springer Science & Business Media
ISBN 13 : 3540264361
Total Pages : 505 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Pediatric Brain and Spine by : L.M. Ketonen

Download or read book Pediatric Brain and Spine written by L.M. Ketonen and published by Springer Science & Business Media. This book was released on 2005-10-28 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: MR Imaging and Spectroscopy of the Developing Brain.- Congenital Malformation of the Brain.- Inherited Neurological Diseases and Disorders of Myelin.- Acquired Toxic and Metabolic Brain Disorders.- Tumors: Paratentorial Neoplasms.- Tumors: Supratentorial Neoplasms.- Brain Damage.- Miscellaneous.- Vascular Abnormalities.- Temporal Bone.- Spine.- Fetal Imaging.

Neuroimaging I

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Publisher : Springer Science & Business Media
ISBN 13 : 9780306452284
Total Pages : 366 pages
Book Rating : 4.4/5 (522 download)

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Book Synopsis Neuroimaging I by : Erin D. Bigler

Download or read book Neuroimaging I written by Erin D. Bigler and published by Springer Science & Business Media. This book was released on 1996-09-30 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recent advents in neuroimaging, the brain had been inaccessible to in vivo visualization, short of neurosurgical procedures or some unfortunate traumatic exposure. It is a tribute to the early contributors to clinical neuroscience that through what, by today's standards, would be deemed extremely crude measure ments, advancements in understanding brain function were made. For example, the theories of higher cortical functions of the brain by Aleksandr Luria or Hans-Lukas Teuber in the 1950s were essentially based on military subjects who sustained traumatic head wounds during World War II. These researchers could inspect the patient and determine where penetrating entrance and exit wounds were on the head; sometimes they had skull films to identify entrance and exit fracture wounds, sometimes neurosurgical reports were available, and Luria even had the opportunity to acutely examine some patients with exposed wounds. Thus, one would take whatever information might be available and infer what regions of the brain were involved but could never actually visualize the brain. Of course, this changed dramatically with the introduction of brain imag ing in the 1970s, but it really was not until the 1990s that analysis and image display technologies finally caught up with the basic brain-imaging methods of computerized tomography (CT) and magnetic resonance imaging (MRI).

Neurology of the Newborn

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Publisher : Elsevier Health Sciences
ISBN 13 : 1416039953
Total Pages : 1109 pages
Book Rating : 4.4/5 (16 download)

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Book Synopsis Neurology of the Newborn by : Joseph J. Volpe

Download or read book Neurology of the Newborn written by Joseph J. Volpe and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 1109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the insights in neonatal neurology. This title describes from the discoveries in genetics through the advances in the diagnosis and management of neurologic disorders. It delivers clinical guidance you need to provide effective care for neonates with neurological conditions.

Physiology of Myelin Forming Cells, from Myelination to Neural Modulators

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Publisher : Frontiers Media SA
ISBN 13 : 2889632741
Total Pages : 173 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Physiology of Myelin Forming Cells, from Myelination to Neural Modulators by : Mauricio Antonio Retamal

Download or read book Physiology of Myelin Forming Cells, from Myelination to Neural Modulators written by Mauricio Antonio Retamal and published by Frontiers Media SA. This book was released on 2020-01-16 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates

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Publisher : Springer
ISBN 13 : 3319766260
Total Pages : 380 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates by : Susanne Radtke-Schuller

Download or read book Cyto- and Myeloarchitectural Brain Atlas of the Ferret (Mustela putorius) in MRI Aided Stereotaxic Coordinates written by Susanne Radtke-Schuller and published by Springer. This book was released on 2018-11-04 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Description This stereotaxic atlas of the ferret brain provides detailed architectonic subdivisions of the cortical and subcortical areas in the ferret brain using high-quality histological material stained for cells and myelin together with in vivo magnetic resonance (MR) images of the same animal. The skull-related position of the ferret brain was established according to in vivo MRI and additional CT measurements of the skull. Functional denotations from published physiology and connectivity studies are mapped onto the atlas sections and onto the brain surface, together with the architectonic subdivisions. High-resolution MR images are provided at levels of the corresponding histology atlas plates with labels of the respective brain structures. The book is the first atlas of the ferret brain and the most detailed brain atlas of a carnivore available to date. It provides a common reference base to collect and compare data from any kind of research in the ferret brain. Key Features Provides the first ferret brain atlas with detailed delineations of cortical and subcortical areas in frontal plane. Provides the most detailed brain atlas of a carnivore to date. Presents a stereotaxic atlas coordinate system derived from high-quality histological material and in vivo magnetic resonance (MR) images of the same animal. Covers the ferret brain from forebrain to spinal cord at intervals of 0.6 mm on 58 anterior-posterior levels with 5 plates each. Presents cell (Nissl) stained frontal sections (plate 1) and myelin stained sections (plate 2) in a stereotaxic frame. Provides detailed delineations of brain structures and their denomination on a Nissl stained background on a separate plate (3). Compiles abbreviations on plate 4, a plate that also displays the low resolution MRI of the atlas brain with the outlines of the Nissl sections in overlay. Displays high-resolution MR images at intervals of 0.15 mm from another animal with labeled brain structures as plate 5 corresponding to the anterior-posterior level of each atlas plate. Provides detailed references used for delineation of brain areas. Target audience of the book: The book addresses researchers and students in neurosciences who are interested in brain anatomy in general (e.g., for translational purposes/comparative aspects), particularly those who study the ferret as important animal model of growing interest in neurosciences.

Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine

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Publisher : Springer
ISBN 13 : 3319095226
Total Pages : 929 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine by : Miguel Angel Reina

Download or read book Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine written by Miguel Angel Reina and published by Springer. This book was released on 2014-11-26 with total page 929 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first atlas to depict in high-resolution images the fine structure of the spinal canal, the nervous plexuses, and the peripheral nerves in relation to clinical practice. The Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine contains more than 1500 images of unsurpassed quality, most of which have never been published, including scanning electron microscopy images of neuronal ultrastructures, macroscopic sectional anatomy, and three-dimensional images reconstructed from patient imaging studies. Each chapter begins with a short introduction on the covered subject but then allows the images to embody the rest of the work; detailed text accompanies figures to guide readers through anatomy, providing evidence-based, clinically relevant information. Beyond clinically relevant anatomy, the book features regional anesthesia equipment (needles, catheters, surgical gloves) and overview of some cutting edge research instruments (e.g. scanning electron microscopy and transmission electron microscopy). Of interest to regional anesthesiologists, interventional pain physicians, and surgeons, this compendium is meant to complement texts that do not have this type of graphic material in the subjects of regional anesthesia, interventional pain management, and surgical techniques of the spine or peripheral nerves.