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Mutating Concepts Evolving Disciplines Genetics Medicine And Society
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Book Synopsis Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society by : L.S. Parker
Download or read book Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society written by L.S. Parker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume employs philosophical and historical perspectives to shed light on classic social, ethical, and philosophical issues raised with renewed urgency against the backdrop of the mapping of the human genome. Philosophers and historians of science and medicine, ethicists, and those interested in the reciprocal influence of science and other cultural practices will find the arguments and observations offered fascinating and indispensable.
Book Synopsis Crumbling Genome by : Alexey S. Kondrashov
Download or read book Crumbling Genome written by Alexey S. Kondrashov and published by John Wiley & Sons. This book was released on 2017-05-16 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thought-provoking exploration of deleterious mutations in the human genome and their effects on human health and wellbeing Despite all of the elaborate mechanisms that a cell employs to handle its DNA with the utmost care, a newborn human carries about 100 new mutations, originated in their parents, about 10 of which are deleterious. A mutation replacing just one of the more than three billion nucleotides in the human genome may lead to synthesis of a dysfunctional protein, and this can be inconsistent with life or cause a tragic disease. Several percent of even young people suffer from diseases that are caused, exclusively or primarily, by pre?]existing and new mutations in their genomes, including both a wide variety of genetically simple Mendelian diseases and diverse complex diseases such as birth anomalies, diabetes, and schizophrenia. Milder, but still substantial, negative effects of mutations are even more pervasive. As of now, we possess no means of reducing the rate at which mutations appear spontaneously. However, the recent flood of genomic data made possible by next-generation methods of DNA sequencing, enabled scientists to explore the impacts of deleterious mutations on humans with previously unattainable precision and begin to develop approaches to managing them. Written by a leading researcher in the field of evolutionary genetics, Crumbling Genome reviews the current state of knowledge about deleterious mutations and their effects on humans for those in the biological sciences and medicine, as well as for readers with only a general scientific literacy and an interest in human genetics. Provides an extensive introduction to the fundamentals of evolutionary genetics with an emphasis on mutation and selection Discusses the effects of pre-existing and new mutations on human genotypes and phenotypes Provides a comprehensive review of the current state of knowledge in the field and considers crucial unsolved problems Explores key ethical, scientific, and social issues likely to become relevant in the near future as the modification of human germline genotypes becomes technically feasible Crumbling Genome is must-reading for students and professionals in human genetics, genomics, bioinformatics, evolutionary biology, and biological anthropology. It is certain to have great appeal among all those with an interest in the links between genetics and evolution and how they are likely to influence the future of human health, medicine, and society.
Book Synopsis The Philosophical Diseases of Medicine and their Cure by : Josef Seifert
Download or read book The Philosophical Diseases of Medicine and their Cure written by Josef Seifert and published by Springer Science & Business Media. This book was released on 2004-10-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: At all times physicians were bound to pursue not only medical tasks, but to reflect also on the many anthropological and metaphysical aspects of their discipline, such as on the nature of life and death, of health and sickness, and above all on the vital ethical dimensions of their practice. For centuries, almost for two millennia, how ever, those who practiced medicine lived in a relatively clearly defined ethical and implicitly philosophical or religious 'world-order' within which they could safely turn to medical practice, knowing right from wrong, or at least being told what to do and what not to do. Today, however, the situation has radically changed, mainly due to three quite different reasons: First and most obviously, physicians today are faced with a tremendous development of new possibilities and techniques which allow previously unheard of medical interventions (such as cloning, cryo-conservation, ge netic interference, etc. ) which call out for ethical reflection and wise judgment but regarding which there is no legal and medical ethical tradition. Traditional medical education did not prepare physicians for coping with this new brave world of mod em medicine. Secondly, there are the deep philosophical crises and the philosophical diseases of medicine mentioned in the preface that lead to a break-down of firm and formative legal and ethical norms for medical actions.
Book Synopsis Philosophy and Design by : Pieter E. Vermaas
Download or read book Philosophy and Design written by Pieter E. Vermaas and published by Springer Science & Business Media. This book was released on 2007-12-05 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the reader with an integrated overview of state-of-the-art research in philosophy and ethics of design in engineering and architecture. It contains twenty-five essays that focus on engineering designing in its traditional sense, on designing in novel engineering domains, and on architectural and environmental designing. This volume enables the reader to overcome the traditional separation between engineering designing and architectural designing.
Book Synopsis Research Ethics by : Ana Smith Iltis
Download or read book Research Ethics written by Ana Smith Iltis and published by Routledge. This book was released on 2006-01-16 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine in the twenty-first century is increasingly reliant on research to guarantee the safety and efficacy of medical interventions. As a result, the need to understand the ethical issues that research generates is becoming essential. This volume introduces the principal areas of concern in research on human subjects, offering a framework for understanding research ethics, and the relationship between ethics and compliance. Research Ethics brings together leading scholars in bioethics and the topics covered include the unique concerns that arise in specific areas of research such as gene therapy and stem cell research. Individual chapters also address the ethical issues that occur when conducting research with specific populations such as infants or adolescents, and the volume looks at important emerging questions in human subjects research, namely financial conflicts of interest and the interpretation of scientific data.
Book Synopsis The Ethics of Managed Care: Professional Integrity and Patient Rights by : W.B. Bondeson
Download or read book The Ethics of Managed Care: Professional Integrity and Patient Rights written by W.B. Bondeson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection provides a philosophical and historical analysis of the development and current situation of managed care. It discusses the relationship between physician professionalism and patient rights to affordable, high quality care. Its special feature is its depth of analysis as the philosophical, social, and economic issues of managed care are developed. It will be of interest to educated readers in their role as patients and to all levels of medical and health care professionals.
Book Synopsis A Companion to the Philosophy of Biology by : Sahotra Sarkar
Download or read book A Companion to the Philosophy of Biology written by Sahotra Sarkar and published by John Wiley & Sons. This book was released on 2010-11-08 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: A COMPANION TO THE PHILOSOPHY OF BIOLOGY “Sarkar is to be congratulated for assembling this talented team of philosophers, who are themselves to be congratulated for writing these interesting essays on so many fascinating areas in philosophy of biology. This book will be a wonderful resource for future work.” Elliot Sober, University of Wisconsin-Madison “Many of the discussions here start with a definition of terms and a historical context of the subject before delving into the deeper philosophical issues, making it a useful reference for students of biology as well as philosophy.” Northeastern Naturalist “The topics that are addressed are done so well. This book will appeal to the advanced student and knowledgeable amateur and may prove useful catalyst for discussion among research teams or those engaged in cross-disciplinary studies.” Reference Reviews A Companion to the Philosophy of Biology offers concise overviews of philosophical issues raised by all areas of biology. Addressing both traditional and emerging areas of philosophical interest, the volume focuses on the philosophical implications of evolutionary theory as well as key topics such as molecular biology, immunology, and ecology Comprising essays by top scholars in the field, this volume is an authoritative guide for professional philosophers, historians, sociologists and biologists, as well as an accessible reference work for students seeking to learn about this rapidly-changing field.
Book Synopsis Plant Cytogenetics, Breeding and Evolution by : Bentlee Salinas
Download or read book Plant Cytogenetics, Breeding and Evolution written by Bentlee Salinas and published by Scientific e-Resources. This book was released on 2018-12-21 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are about 300-315 thousand species of plants, of which the great majority, some 260-290 thousand, are seed plants. Green plants provide a substantial proportion of the world's molecular oxygen and are the basis of most of Earth's Ecologies, especially on land. Plants that produce grains, fruits and vegetables form humankind's basic foodstuffs, and have been domesticated for millennia. Plants play many roles in culture. They are used as ornaments and, until recently and in great variety, they have served as the source of most medicines and drugs. The scientific study of plants is known as botany, a branch of biology. Plant Cytogenetics, Breeding and Evolution Plant Cytogenetics comprises a topic of broad interest and increasing importance in plant science. In keeping with the exciting advances in plant genetics and genomics, we believe that a comprehensive and up-to-date reference on Plant Cytogenetics would be of great interest and value for researchers, instructors, and students with interests in genetics, plant biology, and plant genomics.
Book Synopsis The Ethics of Genetic Engineering by : Roberta M. Berry
Download or read book The Ethics of Genetic Engineering written by Roberta M. Berry and published by Routledge. This book was released on 2013-05-13 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human genetic engineering may soon be possible. The gathering debate about this prospect already threatens to become mired in irresolvable disagreement. After surveying the scientific and technological developments that have brought us to this pass, The Ethics of Genetic Engineering focuses on the ethical and policy debate, noting the deep divide that separates proponents and opponents. The book locates the source of this divide in differing framing assumptions: reductionist pluralist on one side, holist communitarian on the other. The book argues that we must bridge this divide, drawing on the resources from both encampments, if we are to understand and cope with the distinctive problems posed by genetic engineering. These problems, termed "fractious problems," are novel, complex, ethically fraught, unavoidably of public concern, and unavoidably divisive. Berry examines three prominent ethical and political theories – utilitarianism, Kantianism, and virtue ethics – to consider their competency in bridging the divide and addressing these fractious problems. The book concludes that virtue ethics can best guide parental decision making and that a new policymaking approach sketched here, a "navigational approach," can best guide policymaking. These approaches enable us to gain a rich understanding of the problems posed and to craft resolutions adequate to their challenges.
Book Synopsis Taking Biology Seriously by : Inmaculada de Melo-Martín
Download or read book Taking Biology Seriously written by Inmaculada de Melo-Martín and published by Rowman & Littlefield. This book was released on 2005 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Inmaculada de Melo-Martin carefully defend the importance of social and political policies to guide the bio ethical co-construction of a better life for all. As she argues with edifying balance, only by taking biology seriously can we become serious in appreciating its true benefits and counter the illusory hopes and fears that are often projected upon it."--Carl Mitcham, Colorado School of Mines.
Book Synopsis Ethical Issues in Pediatric Organ Transplantation by : Rebecca A. Greenberg
Download or read book Ethical Issues in Pediatric Organ Transplantation written by Rebecca A. Greenberg and published by Springer. This book was released on 2016-05-25 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a theoretical and practical overview of the specific ethical and legal issues in pediatric organ transplantation. Written by a team of leading experts, Ethical Issues in Pediatric Organ Transplantation addresses those difficult ethical questions concerning clinical, organizational, legal and policy issues including donor, recipient and allocation issues. Challenging topics, including children as donors, donation after cardiac death, misattributed paternity, familial conflicts of interest, developmental disability as a listing criteria, small bowel transplant, and considerations in navigating the media are discussed. It serves as a fundamental handbook and resource for pediatricians, transplant health care professionals, trainees, graduate students, scholars, practitioners of bioethics and health policy makers.
Book Synopsis Zionism and the Biology of Jews by : Raphael Falk
Download or read book Zionism and the Biology of Jews written by Raphael Falk and published by Springer. This book was released on 2017-07-18 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a unique perspective on Zionism. The author, a geneticist by training, focuses on science, rather than history. He looks at the claims that Jews constitute a people with common biological roots. An argument that helps provide justification for the aspirations of this political movement dedicated to the return of the Jewish people to their homeland. His study explores two issues. The first considers the assertion that there is a biology of the Jews. The second deals with attempts to integrate this idea into a consistent history. Both issues unfolded against the background of a romantic national culture of Western Europe in the 19th century: Jews, primarily from Eastern Europe, began to believe these notions and soon they took the lead in the re-formulation of Jewish and Zionist existence. The author does not intend to present a comprehensive picture of the biological literature of the origins of a people and the blood relations between them. He also recognizes that the subject is emotionally-loaded. The book does, however, present a profound mediation on three overlapping questions: What is special or unique to the Jews? Who were the genuine Jews? And how can one identify Jews? This volume is a revised and edited English version of Tzionut Vehabiologia shel Hayehudim, published in 2006.
Book Synopsis An Introductory Philosophy of Medicine by : James A. Marcum
Download or read book An Introductory Philosophy of Medicine written by James A. Marcum and published by Springer Science & Business Media. This book was released on 2008-05-07 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the author explores the shifting philosophical boundaries of modern medical knowledge and practice occasioned by the crisis of quality-of-care, especially in terms of the various humanistic adjustments to the biomedical model. To that end he examines the metaphysical, epistemological, and ethical boundaries of these medical models. He begins with their metaphysics, analyzing the metaphysical positions and presuppositions and ontological commitments upon which medical knowledge and practice is founded. Next, he considers the epistemological issues that face these medical models, particularly those driven by methodological procedures undertaken by epistemic agents to constitute medical knowledge and practice. Finally, he examines the axiological boundaries and the ethical implications of each model, especially in terms of the physician-patient relationship. In a concluding Epilogue, he discusses how the philosophical analysis of the humanization of modern medicine helps to address the crisis-of-care, as well as the question of “What is medicine?” The book’s unique features include a comprehensive coverage of the various topics in the philosophy of medicine that have emerged over the past several decades and a philosophical context for embedding bioethical discussions. The book’s target audiences include both undergraduate and graduate students, as well as healthcare professionals and professional philosophers. “This book is the 99th issue of the Series Philosophy and Medicine...and it can be considered a crown of thirty years of intensive and dynamic discussion in the field. We are completely convinced that after its publication, it can be finally said that undoubtedly the philosophy of medicine exists as a special field of inquiry.”
Book Synopsis The Philosophy of Biology by : Kostas Kampourakis
Download or read book The Philosophy of Biology written by Kostas Kampourakis and published by Springer Science & Business Media. This book was released on 2013-06-18 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together for the first time philosophers of biology to write about some of the most central concepts and issues in their field from the perspective of biology education. The chapters of the book cover a variety of topics ranging from traditional ones, such as biological explanation, biology and religion or biology and ethics, to contemporary ones, such as genomics, systems biology or evolutionary developmental biology. Each of the 30 chapters covers the respective philosophical literature in detail and makes specific suggestions for biology education. The aim of this book is to inform biology educators, undergraduate and graduate students in biology and related fields, students in teacher training programs, and curriculum developers about the current state of discussion on the major topics in the philosophy of biology and its implications for teaching biology. In addition, the book can be valuable to philosophers of biology as an introductory text in undergraduate and graduate courses.
Book Synopsis Cut-and-Paste Genetics by : Sahotra Sarkar
Download or read book Cut-and-Paste Genetics written by Sahotra Sarkar and published by Rowman & Littlefield. This book was released on 2021-09-15 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of CRISPR/Cas9 technology has revolutionized gene editing. The Nobel prize for chemistry was awarded to Emmanuelle Charpentier and Jennifer Doudna, the scientists responsible for its discovery, in 2020 and it is considered the frontier of sophisticated medical science. This technology contains the promise that both gene therapy and eugenic control of human evolution is possible, even plausible, in our near future. This book looks at these developements in the context of the history of previous social and scientific attempts at genetic editing, and explores the policy and ethical challenges they raise. It presents the case for altering the human germ-line (which contains and controls hereditary genetic information) to eliminate a large number of genetic diseases controlled by a single or few genes, while pointing out that gene therapy is likely to be ineffective for diseases with more complex causes. In parallel it explores the possibility of genetic enhancement in a set of case studies. But it also argues that, in general, genetic enhancement is ethically problematic and should be approached with caution. Given the success of CRISPR/Cas9 gene editing, and the explosion of related techniques, in practice it would be virtually impossible to ban germ-line editing in our future. A more useful goal is to put regulation in place, with oversight that represents the interests of society. That, in turn, requires an informed public discussion of these issues, which is the intention of this book.
Book Synopsis Genetics and Genetic Engineering by : Tomas Cannon
Download or read book Genetics and Genetic Engineering written by Tomas Cannon and published by Scientific e-Resources. This book was released on 2018-12-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetics and Genetic Engineering explores the great discoveries in genetics-the study of genes and the inherited information they contain. Genetic engineering alters the genetic make-up of an organism using techniques that remove heritable material or that introduce DNA prepared outside the organism either directly into the host or into a cell that is then fused or hybridized with the host. This involves using recombinant nucleic acid (DNA or RNA) techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro-injection, macro-injection and micro-encapsulation techniques. Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genes using biotechnology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA is obtained by either isolating or copying the genetic material of interest using recombinant DNA methods or by artificially synthesizing the DNA. A construct is usually created and used to insert this DNA into the host organism. The first recombinent DNA molecule was made by Paul Berg in 1972 by combining DNA from the monkey virus SV40with the lambda virus. As well as inserting genes, the process can be used to remove, or "e;knock out"e;, genes. The new DNA can be inserted randomly, or targeted to a specific part of the genome. This book will prove equally useful for physicians, nurses, animal breeders, and laboratory technicians-in fact, everyone whose daily work involves genetics and genetic engineering.
Book Synopsis Landscapes of Collectivity in the Life Sciences by : Snait B. Gissis
Download or read book Landscapes of Collectivity in the Life Sciences written by Snait B. Gissis and published by MIT Press. This book was released on 2018-01-12 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Broad perspective on collectivity in the life sciences, from microorganisms to human consensus, and the theoretical and empirical opportunities and challenges. Many researchers and scholars in the life sciences have become increasingly critical of the traditional methodological focus on the individual. This volume counters such methodological individualism by exploring recent and influential work in the life sciences that utilizes notions of collectivity, sociality, rich interactions, and emergent phenomena as essential explanatory tools to handle numerous persistent scientific questions in the life sciences. The contributors consider case studies of collectivity that range from microorganisms to human consensus, discussing theoretical and empirical challenges and the innovative methods and solutions scientists have devised. The contributors offer historical, philosophical, and biological perspectives on collectivity, and describe collective phenomena seen in insects, the immune system, communication, and human collectivity, with examples ranging from cooperative transport in the longhorn crazy ant to the evolution of autobiographical memory. They examine ways of explaining collectivity, including case studies and modeling approaches, and explore collectivity's explanatory power. They present a comprehensive look at a specific case of collectivity: the Holobiont notion (the idea of a multi-species collective, a host and diverse microorganisms) and the hologenome theory (which posits that the holobiont and its hologenome are a unit of adaption). The volume concludes with reflections on the work of the late physicist Eshel Ben-Jacob, pioneer in the study of collective phenomena in living systems. Contributors Oren Bader, John Beatty, Dinah R. Davison, Daniel Dor, Ofer Feinerman, Raghavendra Gadagkar, Scott F. Gilbert, Snait B. Gissis, Deborah M. Gordon, James Griesemer, Zachariah I. Grochau-Wright, Erik R. Hanschen, Eva Jablonka, Mohit Kumar Jolly, Anat Kolumbus, Ehud Lamm, Herbert Levine, Arnon Levy, Xue-Fei Li, Elisabeth A. Lloyd, Yael Lubin, Eva Maria Luef, Ehud Meron, Richard E. Michod, Samir Okasha, Simone Pika, Joan Roughgarden, Eugene Rosenberg, Ayelet Shavit, Yael Silver, Alfred I. Tauber, Ilana Zilber-Rosenberg
