Multivariate Analysis Of Mr Images In Temporal Lobe Epilepsy

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Multivariate Analysis of MR Images in Temporal Lobe Epilepsy

Author : Diego H. Cantor-Rivera
Publisher :
ISBN 13 :
Total Pages : 406 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Multivariate Analysis of MR Images in Temporal Lobe Epilepsy by : Diego H. Cantor-Rivera

Download or read book Multivariate Analysis of MR Images in Temporal Lobe Epilepsy written by Diego H. Cantor-Rivera and published by . This book was released on 2015 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy stands aside from other neurological diseases because clinical patterns of progression are unknown: The etiology of each epilepsy case is unique and so it is the individual prognosis. Temporal lobe epilepsy (TLE) is the most frequent type of focal epilepsy and the surgical excision of the hippocampus and the surrounding tissue is an accepted treatment in refractory cases, specially when seizures become frequent increasingly affecting the performance of daily tasks and significantly decreasing the quality of life of the patient. The sensitivity of clinical imaging is poor for patients with no hippocampal involvement and invasive procedures such as the Wada test and intracranial EEG are required to detect and lateralize epileptogenic tissue. This thesis develops imaging processing techniques using quantitative relaxometry and diffusion tensor imaging with the aiming to provide a less invasive alternative when detectability is low. Chapter 2 develops the concept of individual feature maps on regions of interest. A laterality score on these maps correctly distinguished left TLE from right TLE in 12 out of 15 patients. Chapter 3 explores machine learning models to detect TLE, obtaining perfect classification for left patients, and 88.9% accuracy for right TLE patients. Chapter 4 focuses on temporal lobe asymmetry developing a voxel-based method for assessing asymmetry and verifying its applicability to individual predictions (92% accuracy) and group-wise statistical analyses. Informative ROI and voxel-based informative features are described for each experiment, demonstrating the relative importance of mean diffusivity over other MR imaging alternatives in identification and lateralization of TLE patients. Finally, the conclusion chapter discuss contributions, main limitations and outlining options for future research.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Author : Juerg Hodler
Publisher : Springer Nature
ISBN 13 : 303038490X
Total Pages : 252 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Diseases of the Brain, Head and Neck, Spine 2020–2023 by : Juerg Hodler

Download or read book Diseases of the Brain, Head and Neck, Spine 2020–2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Magnetic Resonance in Epilepsy

Author : Ruben Kuzniecky
Publisher : Academic Press
ISBN 13 : 9780124311527
Total Pages : 476 pages
Book Rating : 4.3/5 (115 download)

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Book Synopsis Magnetic Resonance in Epilepsy by : Ruben Kuzniecky

Download or read book Magnetic Resonance in Epilepsy written by Ruben Kuzniecky and published by Academic Press. This book was released on 2004-12-16 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders. *Provides a crucial update of recent advances in imaging techniques *Timely publication as subject of neuroimaging is a very "hot" area in both clinical epilepsy and basic neuroscience research *Editors are well-respected in this field

Neuroimaging in Epilepsy

Author : Harry Chugani, MD
Publisher : Oxford University Press
ISBN 13 : 0199711526
Total Pages : pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Neuroimaging in Epilepsy by : Harry Chugani, MD

Download or read book Neuroimaging in Epilepsy written by Harry Chugani, MD and published by Oxford University Press. This book was released on 2010-11-23 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Perhaps the most important achievements in the field of epileptology in the past two decades have been in the neuroimaging and genetic breakthroughs as applied to patients with epilepsy. Indeed, neuroimaging has become a vital part in the study of epilepsy, affecting broad aspects of the disorder ranging from diagnosis and classification to treatment and prognosis. Neuroimaging in epilepsy encompasses many different approaches that have reached various levels of expertise across epilepsy centers worldwide. This book discusses every imaging modality used to gather information on epilepsy. Each technique is described by world experts and epilepsy centers worldwide.

The Epilepsies

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
ISBN 13 :
Total Pages : 570 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Epilepsies by : Chrysostomos P. Panayiotopoulos

Download or read book The Epilepsies written by Chrysostomos P. Panayiotopoulos and published by Springer. This book was released on 2005 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

MRI-Negative Epilepsy

Author : Elson L. So
Publisher : Cambridge University Press
ISBN 13 : 110703423X
Total Pages : 259 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis MRI-Negative Epilepsy by : Elson L. So

Download or read book MRI-Negative Epilepsy written by Elson L. So and published by Cambridge University Press. This book was released on 2015-03-26 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book critically appraises the role and value of specific diagnostic and treatment techniques for drug-resistant, MRI-negative epilepsy. The authors present the evidence and share their expertise on the diagnostic options and surgical approaches that make epilepsy surgery possible and worthwhile in this complex and challenging condition.

Magnetic Resonance Scanning and Epilepsy

Author : Simon D. Shorvon
Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Magnetic Resonance Scanning and Epilepsy by : Simon D. Shorvon

Download or read book Magnetic Resonance Scanning and Epilepsy written by Simon D. Shorvon and published by Springer Science & Business Media. This book was released on 1994 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practitioners and researchers from a broad range of disciplines and three continents review the status of magnetic resonance imaging and scanning in epilepsy, and the current research and where is it likely to lead. The 53 papers, from a workshop in Chalfont St Peter, England, October 1992, discuss

MRI in Epilepsy

Author : Horst Urbach
Publisher : Springer Science & Business Media
ISBN 13 : 3642251382
Total Pages : 270 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis MRI in Epilepsy by : Horst Urbach

Download or read book MRI in Epilepsy written by Horst Urbach and published by Springer Science & Business Media. This book was released on 2013-04-16 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: MRI can play an important role in identifying and localizing epileptogenic foci. This book aims to provide the clinical and imaging information required in order to decide whether an MRI scan is appropriate and whether it is likely to be sufficient to detect a lesion. The first part of the book presents background information on epilepsy patients and explains how to perform an MRI examination. Detailed attention is paid to functional MRI and post-processing, and the examination of subcategories of patients is also discussed. The second part of the book then documents the MRI findings obtained in the full range of epileptogenic lesions with the aid of high-quality images. Throughout, emphasis is placed on guiding the reader in the correct interpretation of the imaging findings. Both radiologists and referring physicians will find this book to be an indispensable guide to the optimal use of MRI in epilepsy.

A Volumetric Magnetic Resonance Imaging Study of Mesial Temporal Lobe Epilepsy

Author : Simon Peter Charles Bower
Publisher :
ISBN 13 :
Total Pages : 430 pages
Book Rating : 4.:/5 (223 download)

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Book Synopsis A Volumetric Magnetic Resonance Imaging Study of Mesial Temporal Lobe Epilepsy by : Simon Peter Charles Bower

Download or read book A Volumetric Magnetic Resonance Imaging Study of Mesial Temporal Lobe Epilepsy written by Simon Peter Charles Bower and published by . This book was released on 2001 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Neuroradiology

Author : Frederik Barkhof
Publisher : Springer
ISBN 13 : 9783319685359
Total Pages : pages
Book Rating : 4.6/5 (853 download)

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Book Synopsis Clinical Neuroradiology by : Frederik Barkhof

Download or read book Clinical Neuroradiology written by Frederik Barkhof and published by Springer. This book was released on 2019-04-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This superbly illustrated textbook, endorsed by the European Society of Neuroradiology, explains in detail the clinical importance of neuroradiology in complementing history taking and physical examination during the workup of patients suspected of having neurological, neurosurgical, or psychiatric disorders. The role of imaging of the brain and spinal cord is described across the full range of relevant conditions, including, for example, cerebrovascular diseases, trauma, CSF disorders, developmental malformations, autoimmune diseases, epilepsy, tumors and tumor-like conditions, neurodegenerative diseases, metabolic conditions, and bipolar and depressive disorders. The structured approach to imaging and image analysis will ensure that the book is an invaluable resource for neuroradiologists in training and clinicians alike. Starting from the clinical indication, suggestions for imaging protocols are provided and checklists of common findings and aspects key to interpretation are presented. The book is published within the SpringerReference program, which combines thorough coverage with access to living editions constantly updated via a dynamic peer-review process.

Imaging of Epilepsy

Author : John M. Stern
Publisher : Springer Nature
ISBN 13 : 3030866726
Total Pages : 354 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Imaging of Epilepsy by : John M. Stern

Download or read book Imaging of Epilepsy written by John M. Stern and published by Springer Nature. This book was released on 2022-01-03 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: This clinically-oriented collection of brain imaging results provides a unique and helpful approach to the epilepsy evaluation. The atlas is divided into sections according to general clinical categories with each category including a collection of clinical examples that span the category. Each example includes images across the relevant imaging modalities that relate to one patient, whose history accompanies the images. This case-based organization with clinical history and multiple images offers a complete visual understanding of the imaging findings and the corresponding relationship of each finding to the clinical presentation, treatment, and outcome. Images for the book are from the UCLA Seizure Disorder Center, which is a referral center that serves a large outpatient epilepsy patient population and performs approximately 500 inpatient epilepsy evaluations annually. Comprehensive and richly illustrated, this book will serve as a convenient resource in neurologic and radiologic practice, and useful for board exam review.

Neuroimaging in Epilepsy

Author : Gregory Cascino
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neuroimaging in Epilepsy by : Gregory Cascino

Download or read book Neuroimaging in Epilepsy written by Gregory Cascino and published by Butterworth-Heinemann. This book was released on 1996 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: ·A practical and well-illustrated text on the techniques and procedures used in imaging in patients with epilepsy · There exists no other textbook devoted solely to this topic The value of neuroimaging in patients with seizures is great. Patients with partial or focal (restricted to a certain portion of the brain) require CT or MRI scans to determine whether a brain lesion is associated with the epilepsy; PET scans help to elucidate some of the metabolic changes that occur during seizures. Evaluation and management of patients with epilepsy now routinely incorporate imaging techniques, whether or not the patient undergoes surgery. Drs. Cascino and Jack have edited a highly illustrated and authoritative text on the topic. They have enlisted internationally known authors from the US, Canada, England, and Australia. In addition, the book is being published under the auspices of the Mayo Foundation.

Common Pitfalls in Epilepsy

Author : Dieter Schmidt
Publisher : Cambridge University Press
ISBN 13 : 1316409716
Total Pages : 263 pages
Book Rating : 4.3/5 (164 download)

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Book Synopsis Common Pitfalls in Epilepsy by : Dieter Schmidt

Download or read book Common Pitfalls in Epilepsy written by Dieter Schmidt and published by Cambridge University Press. This book was released on 2018-06-07 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is amongst the most frequently encountered of neurological disorders, yet its diagnosis and management is fraught with pitfalls. Issues surrounding differential diagnosis, seizure type, underlying causes, EEG interpretations, treatment options and prognoses can often trip-up clinicians. Common Epilepsy Pitfalls: Case-Based Learning, is a comprehensive guide to anticipating and managing the pitfalls in the diagnosis and management of epilepsy. Real-life cases are presented along with pragmatic recommendations for courses of action that guide the reader through accurate and effective epilepsy diagnosis and treatment. Cases have been chosen to answer key questions such as: the first seizure – is it epilepsy? Which drug? When should stopping treatment be considered? What to do in an epileptic emergency? Containing detailed coverage of psychiatric, social and family issues – and authored by world experts in epilepsy management – this text is invaluable for neurologists, internists, family practitioners and advanced medical students.

Feasibility of T1rho Imaging in Lateralization of the Epileptogenic Zones in Patients with Mesial Temporal Lobe Epilepsy

Author : Xiao Li
Publisher :
ISBN 13 : 9781361337349
Total Pages : pages
Book Rating : 4.3/5 (373 download)

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Book Synopsis Feasibility of T1rho Imaging in Lateralization of the Epileptogenic Zones in Patients with Mesial Temporal Lobe Epilepsy by : Xiao Li

Download or read book Feasibility of T1rho Imaging in Lateralization of the Epileptogenic Zones in Patients with Mesial Temporal Lobe Epilepsy written by Xiao Li and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Feasibility of T1rho Imaging in Lateralization of the Epileptogenic Zones in Patients With Mesial Temporal Lobe Epilepsy: Comparisons With MR Volumetry and T2 Relaxometry" by Xiao, Li, 李瀟, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Underling neuronal loss and subsequent hippocampal sclerosis, as reflected by hippocampal atrophy on structural magnetic resonance (MR) imaging, are the dominant findings in the patient with mesial temporal lobe epilepsy (MTLE). Yet, prolongation of T2 relaxation time has also been reported as an early marker for MTLE, but it is a rather insensitive marker. Typical age-related atrophy often constitutes a significant confounding factor, and atrophy often represents a late sign in hippocampal sclerosis. In this connection, there is an urge for a sensitive independent predictor for the early detection of MTLE. T1rho MR imaging provides a distinct contrast mechanism in tissue characteristics. It is sensitive to physio-chemical processes and has been tested successfully in Alzheimer's disease, Parkinson's disease and certain brain tumors. Therefore, it is possible to depict early biochemical change in patients with MTLE by means of measuring the changes in T1rho relaxation time. T1rho relaxation time is not affected by age-related atrophic changes and thus can be used as an independent marker. In this preliminary study, we aimed to assess the feasibility of T2 relaxometry and T1rho MR imaging in identification of the atrophied zones in patients with MTLE. Seven patients with unilateral MTLE and fourteen normal subjects were recruited. Three-dimensional T1-weighted imaging, axial T2 relaxometry and T1rho imaging were performed on a 3T MR scanner. Hippocampal head, hippocampal body, hippocampal tail and amygdala were contoured on the axial T2-weighted images and then co-registered onto T2 relaxometry and T1rho images. A combination of visual and quantitative volumetric assessment was used as the primary end outcome. For T2 relaxometry and T1rho imaging, their respective relaxation times together with the corresponding right-left asymmetric ratios were calculated for subsequent analysis. Abnormal right-left asymmetric ratio is defined as a deviation of 2SD from the mean of the Z-score. In the lateralizing epileptogenic zones, T1rho yielded an overall accuracy of 92.9% (sensitivity 100%, specificity 60%), while T2 relaxometry yielded an overall accuracy of 71.4% (sensitivity 65.2%, specificity 100%) only. T1rho imaging is thus superior to T2 relaxometry (P = 0.036, by chi-square test). To conclude, the present study indicated that T1rho is feasible and potentially useful to serve as a non-invasive imaging tool in the detection of lateralization of the epileptogenic zone in patients with MTLE. It can also facilitate prompt diagnosis and longitudinal disease monitoring. In addition, the generation of associated color-coded parametric map can provide an easy mean for direct visual analysis. DOI: 10.5353/th_b5186503 Subjects: Temporal lobe epilepsy - Magnetic resonance imaging

Imaging Biomarkers in Epilepsy

Author : Andrea Bernasconi
Publisher : Cambridge University Press
ISBN 13 : 1107108357
Total Pages : 263 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Imaging Biomarkers in Epilepsy by : Andrea Bernasconi

Download or read book Imaging Biomarkers in Epilepsy written by Andrea Bernasconi and published by Cambridge University Press. This book was released on 2019-01-10 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assembles world-class expertise on clinical and molecular imaging-derived biomarkers, presenting neuroimaging in epilepsy in a broad neuroscientific context.

Quantitative Magnetic Resonance Image Analysis Studies of Brain Morphology in Patients with Temporal Lobe Epilepsy in a Large Clinical Database

Download Quantitative Magnetic Resonance Image Analysis Studies of Brain Morphology in Patients with Temporal Lobe Epilepsy in a Large Clinical Database PDF Online Free

Author : Simon Sean Keller
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (17 download)

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Book Synopsis Quantitative Magnetic Resonance Image Analysis Studies of Brain Morphology in Patients with Temporal Lobe Epilepsy in a Large Clinical Database by : Simon Sean Keller

Download or read book Quantitative Magnetic Resonance Image Analysis Studies of Brain Morphology in Patients with Temporal Lobe Epilepsy in a Large Clinical Database written by Simon Sean Keller and published by . This book was released on 2004 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Understanding Epilepsy

Author : Vibhangini S. Wasade
Publisher : Cambridge University Press
ISBN 13 : 1108718906
Total Pages : 501 pages
Book Rating : 4.1/5 (87 download)

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Book Synopsis Understanding Epilepsy by : Vibhangini S. Wasade

Download or read book Understanding Epilepsy written by Vibhangini S. Wasade and published by Cambridge University Press. This book was released on 2019-11-21 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, accessible synthesis of current information on epilepsy for medical trainees and physicians preparing for board certification.