Multiscale Soft Tissue Mechanics And Mechanobiology

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Multiscale Soft Tissue Mechanics and Mechanobiology

Author : Gerhard A. Holzapfel
Publisher : Springer
ISBN 13 : 9789402415124
Total Pages : 0 pages
Book Rating : 4.4/5 (151 download)

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Book Synopsis Multiscale Soft Tissue Mechanics and Mechanobiology by : Gerhard A. Holzapfel

Download or read book Multiscale Soft Tissue Mechanics and Mechanobiology written by Gerhard A. Holzapfel and published by Springer. This book was released on 2018-09-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers aspects of multiscale modeling of the mechanics and mechanobiology of soft biological tissues. The individual contributions focus on the constitutive modeling from the micro to the macro level in addition to computational modeling and simulation. It consists of peer-reviewed papers written by leading international authorities and will serve as a major state-of-the-art source of reference for the next few years. It includes both review articles and original articles. Previously published in the Journal of Elasticity, Volume 129, Issue 1-2, December 2017.

Multiscale Modeling in Biomechanics and Mechanobiology

Author : Suvranu De
Publisher : Springer
ISBN 13 : 1447165993
Total Pages : 287 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Multiscale Modeling in Biomechanics and Mechanobiology by : Suvranu De

Download or read book Multiscale Modeling in Biomechanics and Mechanobiology written by Suvranu De and published by Springer. This book was released on 2014-10-10 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Multiscale Mechanobiology in Tissue Engineering

Author : Damien Lacroix
Publisher : Springer
ISBN 13 : 9811080755
Total Pages : 212 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Multiscale Mechanobiology in Tissue Engineering by : Damien Lacroix

Download or read book Multiscale Mechanobiology in Tissue Engineering written by Damien Lacroix and published by Springer. This book was released on 2018-07-31 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

Multi-scale Extracellular Matrix Mechanics and Mechanobiology

Author : Yanhang Zhang
Publisher : Springer
ISBN 13 : 3030201821
Total Pages : 401 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Multi-scale Extracellular Matrix Mechanics and Mechanobiology by : Yanhang Zhang

Download or read book Multi-scale Extracellular Matrix Mechanics and Mechanobiology written by Yanhang Zhang and published by Springer. This book was released on 2019-07-12 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.

Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation

Author : Jerome Noailly
Publisher : Frontiers Media SA
ISBN 13 : 2889746623
Total Pages : 317 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation by : Jerome Noailly

Download or read book Multiscale Modeling to Tackle the Complexity of Load-Bearing Organ and Tissue Regulation written by Jerome Noailly and published by Frontiers Media SA. This book was released on 2022-03-11 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiscale Simulations and Mechanics of Biological Materials

Author : Shaofan Li
Publisher : John Wiley & Sons
ISBN 13 : 1118402944
Total Pages : 509 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Multiscale Simulations and Mechanics of Biological Materials by : Shaofan Li

Download or read book Multiscale Simulations and Mechanics of Biological Materials written by Shaofan Li and published by John Wiley & Sons. This book was released on 2013-03-19 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiscale Simulations and Mechanics of Biological Materials A compilation of recent developments in multiscale simulation and computational biomaterials written by leading specialists in the field Presenting the latest developments in multiscale mechanics and multiscale simulations, and offering a unique viewpoint on multiscale modelling of biological materials, this book outlines the latest developments in computational biological materials from atomistic and molecular scale simulation on DNA, proteins, and nano-particles, to meoscale soft matter modelling of cells, and to macroscale soft tissue and blood vessel, and bone simulations. Traditionally, computational biomaterials researchers come from biological chemistry and biomedical engineering, so this is probably the first edited book to present work from these talented computational mechanics researchers. The book has been written to honor Professor Wing Liu of Northwestern University, USA, who has made pioneering contributions in multiscale simulation and computational biomaterial in specific simulation of drag delivery at atomistic and molecular scale and computational cardiovascular fluid mechanics via immersed finite element method. Key features: Offers a unique interdisciplinary approach to multiscale biomaterial modelling aimed at both accessible introductory and advanced levels Presents a breadth of computational approaches for modelling biological materials across multiple length scales (molecular to whole-tissue scale), including solid and fluid based approaches A companion website for supplementary materials plus links to contributors’ websites (www.wiley.com/go/li/multiscale)

Solid (Bio)mechanics: Challenges of the Next Decade

Author : Gerhard Sommer
Publisher : Springer Nature
ISBN 13 : 3030923398
Total Pages : 447 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Solid (Bio)mechanics: Challenges of the Next Decade by : Gerhard Sommer

Download or read book Solid (Bio)mechanics: Challenges of the Next Decade written by Gerhard Sommer and published by Springer Nature. This book was released on 2022-06-14 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive and timely overview of the latest developments in the field of biomechanics and extensive knowledge of tissue structure, function, and modeling. Gathering chapters written by authoritative scientists, it reports on a range of continuum and computational models of solids, and related experimental works, for biomechanical applications. It discusses cutting-edge advances such as constitutive modeling and computational simulation of biological tissues and organs under physiological and pathological conditions, and their mechanical characterization. It covers innovative studies on arteries, heart, valvular tissue, and thrombus, brain tumor, muscle, liver, kidney, and stomach, among others. Written in honor of Professor Gerhard A. Holzapfel, the book provides specialized readers with a thorough and timely overview of different types of modeling in biomechanics, and current knowledge about biological structures and function.

Encyclopedia of Biomedical Engineering

Author :
Publisher : Elsevier
ISBN 13 : 0128051442
Total Pages : 2069 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Encyclopedia of Biomedical Engineering by :

Download or read book Encyclopedia of Biomedical Engineering written by and published by Elsevier. This book was released on 2018-09-01 with total page 2069 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Biomedical Engineering, Three Volume Set is a unique source for rapidly evolving updates on topics that are at the interface of the biological sciences and engineering. Biomaterials, biomedical devices and techniques play a significant role in improving the quality of health care in the developed world. The book covers an extensive range of topics related to biomedical engineering, including biomaterials, sensors, medical devices, imaging modalities and imaging processing. In addition, applications of biomedical engineering, advances in cardiology, drug delivery, gene therapy, orthopedics, ophthalmology, sensing and tissue engineering are explored. This important reference work serves many groups working at the interface of the biological sciences and engineering, including engineering students, biological science students, clinicians, and industrial researchers. Provides students with a concise description of the technologies at the interface of the biological sciences and engineering Covers all aspects of biomedical engineering, also incorporating perspectives from experts working within the domains of biomedicine, medical engineering, biology, chemistry, physics, electrical engineering, and more Contains reputable, multidisciplinary content from domain experts Presents a ‘one-stop’ resource for access to information written by world-leading scholars in the field

Multiscale Mechanobiology of Bone Remodeling and Adaptation

Author : Peter Pivonka
Publisher : Springer
ISBN 13 : 3319588451
Total Pages : 295 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Multiscale Mechanobiology of Bone Remodeling and Adaptation by : Peter Pivonka

Download or read book Multiscale Mechanobiology of Bone Remodeling and Adaptation written by Peter Pivonka and published by Springer. This book was released on 2017-06-20 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

Mechanics of Living Tissues

Author : Cédric Laurent
Publisher : John Wiley & Sons
ISBN 13 : 1789451604
Total Pages : 356 pages
Book Rating : 4.7/5 (894 download)

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Book Synopsis Mechanics of Living Tissues by : Cédric Laurent

Download or read book Mechanics of Living Tissues written by Cédric Laurent and published by John Wiley & Sons. This book was released on 2024-08-13 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite their many common features (mechanical behavior, multi-scale structure, evolutionary and living characteristics, etc.), the tissues that make up the human body each have specific characteristics linked to their function, which require the development of dedicated experimental, theoretical and numerical methods. Mechanics of Living Tissues brings together the work of a number of experts to provide an overview of the most recent approaches developed to study the biomechanical behavior of these soft tissues, in order to understand their structure and apparent behavior. Specific tissues are analyzed across the chapters with the aim of developing solutions that address the clinical problems encountered. Conclusions are then drawn regarding future methods that will improve the current state of knowledge of the behavior of these living tissues, in particular with a view to predicting the effect of a pathology or medical procedure on their apparent properties.

Multiscale Biomechanics

Author : Soheil Mohammadi
Publisher : John Wiley & Sons
ISBN 13 : 1119033721
Total Pages : 564 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Multiscale Biomechanics by : Soheil Mohammadi

Download or read book Multiscale Biomechanics written by Soheil Mohammadi and published by John Wiley & Sons. This book was released on 2023-06-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: MULTISCALE BIOMECHANICS Model biomechanical problems at multiple scales with this cutting-edge technology Multiscale modelling is the set of techniques used to solve physical problems which exist at multiple scales either in space or time. It has been shown to have significant applications in biomechanics, the study of biological systems and their structures, which exist at scales from the macroscopic to the microscopic and beyond, and which produce a myriad of overlapping problems. The next generation of biomechanical researchers therefore has need of the latest multiscale modelling techniques. Multiscale Biomechanics offers a comprehensive introduction to these techniques and their biomechanical applications. It includes both the theory of multiscale biomechanical modelling and its practice, incorporating some of the latest research and surveying a wide range of multiscale methods. The result is a thorough yet accessible resource for researchers looking to gain an edge in their biomechanical modelling. Multiscale Biomechanics readers will find: Practical biomechanical applications for a variety of multiscale methods Detailed discussion of soft and hard tissues, and more An introduction to analysis of advanced topics ranging from stenting, drug delivery systems, and artificial intelligence in biomechanics Multiscale Biomechanics is a useful reference for researchers and scientists in any of the life sciences with an interest in biomechanics, as well as for graduate students in mechanical, biomechanical, biomedical, civil, material, and aerospace engineering.

Mechanobiology

Author : Glen L. Niebur
Publisher : Elsevier
ISBN 13 : 0128179325
Total Pages : 256 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Mechanobiology by : Glen L. Niebur

Download or read book Mechanobiology written by Glen L. Niebur and published by Elsevier. This book was released on 2019-12-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena

Cellular and Biomolecular Mechanics and Mechanobiology

Author : Amit Gefen
Publisher : Springer Science & Business Media
ISBN 13 : 3642142184
Total Pages : 553 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Cellular and Biomolecular Mechanics and Mechanobiology by : Amit Gefen

Download or read book Cellular and Biomolecular Mechanics and Mechanobiology written by Amit Gefen and published by Springer Science & Business Media. This book was released on 2010-12-02 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads.

Multiscale Modelling in Biomedical Engineering

Author : Dimitrios I. Fotiadis
Publisher : John Wiley & Sons
ISBN 13 : 1119517354
Total Pages : 404 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Multiscale Modelling in Biomedical Engineering by : Dimitrios I. Fotiadis

Download or read book Multiscale Modelling in Biomedical Engineering written by Dimitrios I. Fotiadis and published by John Wiley & Sons. This book was released on 2023-05-05 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiscale Modelling in Biomedical Engineering Discover how multiscale modeling can enhance patient treatment and outcomes In Multiscale Modelling in Biomedical Engineering, an accomplished team of biomedical professionals delivers a robust treatment of the foundation and background of a general computational methodology for multi-scale modeling. The authors demonstrate how this methodology can be applied to various fields of biomedicine, with a particular focus on orthopedics and cardiovascular medicine. The book begins with a description of the relationship between multiscale modeling and systems biology before moving on to proceed systematically upwards in hierarchical levels from the molecular to the cellular, tissue, and organ level. It then examines multiscale modeling applications in specific functional areas, like mechanotransduction, musculoskeletal, and cardiovascular systems. Multiscale Modelling in Biomedical Engineering offers readers experiments and exercises to illustrate and implement the concepts contained within. Readers will also benefit from the inclusion of: A thorough introduction to systems biology and multi-scale modeling, including a survey of various multi-scale methods and approaches and analyses of their application in systems biology Comprehensive explorations of biomedical imaging and nanoscale modeling at the molecular, cell, tissue, and organ levels Practical discussions of the mechanotransduction perspective, including recent progress and likely future challenges In-depth examinations of risk prediction in patients using big data analytics and data mining Perfect for undergraduate and graduate students of bioengineering, biomechanics, biomedical engineering, and medicine, Multiscale Modelling in Biomedical Engineering will also earn a place in the libraries of industry professional and researchers seeking a one-stop reference to the basic engineering principles of biological systems.

Principles of Regenerative Medicine

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0128098937
Total Pages : 1456 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Regenerative Medicine by : Anthony Atala

Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2018-08-09 with total page 1456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. - Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery - Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs - Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine

Multiscale Biomechanics

Author : Jean-Francois Ganghoffer
Publisher : Elsevier
ISBN 13 : 0081021151
Total Pages : 584 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Multiscale Biomechanics by : Jean-Francois Ganghoffer

Download or read book Multiscale Biomechanics written by Jean-Francois Ganghoffer and published by Elsevier. This book was released on 2018-02-03 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiscale Biomechanics provides new insights on multiscale static and dynamic behavior of both soft and hard biological tissues, including bone, the intervertebral disk, biological membranes and tendons. The physiological aspects of bones and biological membranes are introduced, along with micromechanical models used to compute mechanical response. A modern account of continuum mechanics of growth and remodeling, generalized continuum models to capture internal lengths scales, and dedicated homogenization methods are provided to help the reader with the necessary theoretical foundations. Topics discussed include multiscale methods for fibrous media based on discrete homogenization, generalized continua constitutive models for bone, and a presentation of recent theoretical and numerical advances. In addition, a refresher on continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods is given in separate chapters. Numerical aspects are treated in detail, and simulations are presented to illustrate models. This book is intended for graduate students and researchers in biomechanics interested in the latest research developments, as well as those who wish to gain insight into the field of biomechanics. - Provides a clear exposition of multiscale methods for fibrous media based on discrete homogenization and the consideration of generalized continua constitutive models for bone - Presents recent theoretical and numerical advances for bone remodeling and growth - Includes the necessary theoretical background that is exposed in a clear and self-contained manner - Covers continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods

Multiscale Computer Modeling in Biomechanics and Biomedical Engineering

Author : Amit Gefen
Publisher : Springer Science & Business Media
ISBN 13 : 3642364829
Total Pages : 397 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Multiscale Computer Modeling in Biomechanics and Biomedical Engineering by : Amit Gefen

Download or read book Multiscale Computer Modeling in Biomechanics and Biomedical Engineering written by Amit Gefen and published by Springer Science & Business Media. This book was released on 2014-07-08 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the state-of-the-art in multiscale computer modeling, in terms of both accomplishments and challenges. The information in the book is particularly useful for biomedical engineers, medical physicists and researchers in systems biology, mathematical biology, micro-biomechanics and biomaterials who are interested in how to bridge between traditional biomedical engineering work at the organ and tissue scales, and the newer arenas of cellular and molecular bioengineering.