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Author : Thorsten Dickhaus
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (115 download)
Download or read book Multiple Point Hypothesis Test Problems and Effective Numbers of Tests written by Thorsten Dickhaus and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Xinping Cui
Publisher : CRC Press
ISBN 13 : 0429633882
Total Pages : 418 pages
Book Rating : 4.4/5 (296 download)
Download or read book Handbook of Multiple Comparisons written by Xinping Cui and published by CRC Press. This book was released on 2021-11-18 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts that include originators of some key ideas, chapters in the Handbook of Multiple Testing cover multiple comparison problems big and small, with guidance toward error rate control and insights on how principles developed earlier can be applied to current and emerging problems. Some highlights of the coverages are as follows. Error rate control is useful for controlling the incorrect decision rate. Chapter 1 introduces Tukey's original multiple comparison error rates and point to how they have been applied and adapted to modern multiple comparison problems as discussed in the later chapters. Principles endure. While the closed testing principle is more familiar, Chapter 4 shows the partitioning principle can derive confidence sets for multiple tests, which may become important as the profession goes beyond making decisions based on p-values. Multiple comparisons of treatment efficacy often involve multiple doses and endpoints. Chapter 12 on multiple endpoints explains how different choices of endpoint types lead to different multiplicity adjustment strategies, while Chapter 11 on the MCP-Mod approach is particularly useful for dose-finding. To assess efficacy in clinical trials with multiple doses and multiple endpoints, the reader can see the traditional approach in Chapter 2, the Graphical approach in Chapter 5, and the multivariate approach in Chapter 3. Personalized/precision medicine based on targeted therapies, already a reality, naturally leads to analysis of efficacy in subgroups. Chapter 13 draws attention to subtle logical issues in inferences on subgroups and their mixtures, with a principled solution that resolves these issues. This chapter has implication toward meeting the ICHE9R1 Estimands requirement. Besides the mere multiple testing methodology itself, the handbook also covers related topics like the statistical task of model selection in Chapter 7 or the estimation of the proportion of true null hypotheses (or, in other words, the signal prevalence) in Chapter 8. It also contains decision-theoretic considerations regarding the admissibility of multiple tests in Chapter 6. The issue of selected inference is addressed in Chapter 9. Comparison of responses can involve millions of voxels in medical imaging or SNPs in genome-wide association studies (GWAS). Chapter 14 and Chapter 15 provide state of the art methods for large scale simultaneous inference in these settings.
Author : Thorsten Dickhaus
Publisher : Springer Science & Business Media
ISBN 13 : 3642451829
Total Pages : 182 pages
Book Rating : 4.6/5 (424 download)
Download or read book Simultaneous Statistical Inference written by Thorsten Dickhaus and published by Springer Science & Business Media. This book was released on 2014-01-23 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph will provide an in-depth mathematical treatment of modern multiple test procedures controlling the false discovery rate (FDR) and related error measures, particularly addressing applications to fields such as genetics, proteomics, neuroscience and general biology. The book will also include a detailed description how to implement these methods in practice. Moreover new developments focusing on non-standard assumptions are also included, especially multiple tests for discrete data. The book primarily addresses researchers and practitioners but will also be beneficial for graduate students.
Author : Ignacio Rojas
Publisher : Springer
ISBN 13 : 3319287257
Total Pages : 383 pages
Book Rating : 4.3/5 (192 download)
Download or read book Time Series Analysis and Forecasting written by Ignacio Rojas and published by Springer. This book was released on 2016-05-30 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents selected peer-reviewed contributions from The International Work-Conference on Time Series, ITISE 2015, held in Granada, Spain, July 1-3, 2015. It discusses topics in time series analysis and forecasting, advanced methods and online learning in time series, high-dimensional and complex/big data time series as well as forecasting in real problems. The International Work-Conferences on Time Series (ITISE) provide a forum for scientists, engineers, educators and students to discuss the latest ideas and implementations in the foundations, theory, models and applications in the field of time series analysis and forecasting. It focuses on interdisciplinary and multidisciplinary research encompassing the disciplines of computer science, mathematics, statistics and econometrics.
Author :
Publisher : Academic Press
ISBN 13 : 0128145145
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)
Download or read book Computational Epigenetics and Diseases written by and published by Academic Press. This book was released on 2019-02-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, in the context of human diseases. This book discusses bioinformatics methods for epigenetic analysis specifically applied to human conditions such as aging, atherosclerosis, diabetes mellitus, schizophrenia, bipolar disorder, Alzheimer disease, Parkinson disease, liver and autoimmune disorders, and reproductive and respiratory diseases. Additionally, different organ cancers, such as breast, lung, and colon, are discussed. This book is a valuable source for graduate students and researchers in genetics and bioinformatics, and several biomedical field members interested in applying computational epigenetics in their research. Provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases Summarizes the major computational tools, databases, and strategies for computational epigenetics analysis, such as DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA Covers the major milestones and future directions of computational epigenetics in various kinds of human diseases such as aging, atherosclerosis, diabetes, heart disease, neurological disorders, cancers, blood disorders, liver diseases, reproductive diseases, respiratory diseases, autoimmune diseases, human imprinting disorders, and infectious diseases
Author : Asis Kumar Chattopadhyay
Publisher : Springer
ISBN 13 : 9811312230
Total Pages : 180 pages
Book Rating : 4.8/5 (113 download)
Download or read book Statistics and its Applications written by Asis Kumar Chattopadhyay and published by Springer. This book was released on 2018-08-16 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses recent developments and the latest research in statistics and its applications, primarily in agriculture and industry, survey sampling and biostatistics, gathering articles on a wide variety of topics. Written by leading academics, scientists, researchers and scholars from around the globe to mark the platinum jubilee of the Department of Statistics, University of Calcutta in 2016, the book is a valuable resource for statisticians, aspiring researchers and professionals across educational levels and disciplines.
Author : Shyama Prasad Mukherjee
Publisher : CRC Press
ISBN 13 : 1000617416
Total Pages : 255 pages
Book Rating : 4.0/5 (6 download)
Download or read book A Guide to Research Methodology written by Shyama Prasad Mukherjee and published by CRC Press. This book was released on 2019-09-04 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methodology is meant to provide a broad guideline to facilitate and steer the whole of a research activity in any discipline. With the ambit and amount of research increasing by the day, the need for Research Methodology is being widely appreciated. Against this backdrop, we notice the dearth of well-written books on the subject. A Guide to Research Methodology attempts a balance between the generic approach to research in any domain and the wide array of research methods which are to be used in carrying out different tasks in any research. Discussions on these research methods appropriate in various disciplines have focused on the research tasks, keeping in mind the fact that a single such task like a comparison among alternatives may involve several methods from seemingly distinct areas. Unique features of this volume, as will be evident to a discerning reader, include: A detailed discussion on problem areas for research in several domains An illustrative and ampliated list of research problems drawn from different disciplines which can be pursued by interested research workers A comprehensive delineation of Research Design supported by illustrations An elaborate engagement with models with a note on model uncertainty Focus on recent and emerging models, methods and techniques A novel treatment of data analysis where the nature of data and the objective(s) of analysis justify drawing upon a variety of techniques for analysis This book will serve the purpose of a pre-PhD or a Master-level course-work for students of any discipline with a basic knowledge of quantitative analysis. In fact, anyone aspiring to take up meaningful research work will find the content useful and interesting.
Author : Alexander Holmes
Publisher :
ISBN 13 : 9781998109487
Total Pages : 0 pages
Book Rating : 4.1/5 (94 download)
Download or read book Introductory Business Statistics (paperback, B&w) written by Alexander Holmes and published by . This book was released on 2023-06-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Printed in b&w. Introductory Business Statistics is designed to meet the scope and sequence requirements of the one-semester statistics course for business, economics, and related majors. Core statistical concepts and skills have been augmented with practical business examples, scenarios, and exercises. The result is a meaningful understanding of the discipline, which will serve students in their business careers and real-world experiences.
Author : Daniel Navarro
Publisher : Lulu.com
ISBN 13 : 1326189727
Total Pages : 617 pages
Book Rating : 4.3/5 (261 download)
Download or read book Learning Statistics with R written by Daniel Navarro and published by Lulu.com. This book was released on 2013-01-13 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Learning Statistics with R" covers the contents of an introductory statistics class, as typically taught to undergraduate psychology students, focusing on the use of the R statistical software and adopting a light, conversational style throughout. The book discusses how to get started in R, and gives an introduction to data manipulation and writing scripts. From a statistical perspective, the book discusses descriptive statistics and graphing first, followed by chapters on probability theory, sampling and estimation, and null hypothesis testing. After introducing the theory, the book covers the analysis of contingency tables, t-tests, ANOVAs and regression. Bayesian statistics are covered at the end of the book. For more information (and the opportunity to check the book out before you buy!) visit http://ua.edu.au/ccs/teaching/lsr or http://learningstatisticswithr.com
Author : David Diez
Publisher :
ISBN 13 : 9781943450046
Total Pages : pages
Book Rating : 4.4/5 (5 download)
Download or read book OpenIntro Statistics written by David Diez and published by . This book was released on 2015-07-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The OpenIntro project was founded in 2009 to improve the quality and availability of education by producing exceptional books and teaching tools that are free to use and easy to modify. We feature real data whenever possible, and files for the entire textbook are freely available at openintro.org. Visit our website, openintro.org. We provide free videos, statistical software labs, lecture slides, course management tools, and many other helpful resources.
Author : Narayanaswamy Balakrishnan
Publisher : John Wiley & Sons
ISBN 13 : 0470405090
Total Pages : 1027 pages
Book Rating : 4.4/5 (74 download)
Download or read book Methods and Applications of Statistics in the Life and Health Sciences written by Narayanaswamy Balakrishnan and published by John Wiley & Sons. This book was released on 2009-12-02 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inspired by the Encyclopedia of Statistical Sciences, Second Edition, this volume outlines the statistical tools for successfully working with modern life and health sciences research Data collection holds an essential part in dictating the future of health sciences and public health, as the compilation of statistics allows researchers and medical practitioners to monitor trends in health status, identify health problems, and evaluate the impact of health policies and programs. Methods and Applications of Statistics in the Life and Health Sciences serves as a single, one-of-a-kind resource on the wide range of statistical methods, techniques, and applications that are applied in modern life and health sciences in research. Specially designed to present encyclopedic content in an accessible and self-contained format, this book outlines thorough coverage of the underlying theory and standard applications to research in related disciplines such as biology, epidemiology, clinical trials, and public health. Uniquely combining established literature with cutting-edge research, this book contains classical works and more than twenty-five new articles and completely revised contributions from the acclaimed Encyclopedia of Statistical Sciences, Second Edition. The result is a compilation of more than eighty articles that explores classic methodology and new topics, including: Sequential methods in biomedical research Statistical measures of human quality of life Change-point methods in genetics Sample size determination for clinical trials Mixed-effects regression models for predicting pre-clinical disease Probabilistic and statistical models for conception Statistical methods are explored and applied to population growth, disease detection and treatment, genetic and genomic research, drug development, clinical trials, screening and prevention, and the assessment of rehabilitation, recovery, and quality of life. These topics are explored in contributions written by more than 100 leading academics, researchers, and practitioners who utilize various statistical practices, such as election bias, survival analysis, missing data techniques, and cluster analysis for handling the wide array of modern issues in the life and health sciences. With its combination of traditional methodology and newly developed research, Methods and Applications of Statistics in the Life and Health Sciences has everything students, academics, and researchers in the life and health sciences need to build and apply their knowledge of statistical methods and applications.
Author : Chester Ismay
Publisher : CRC Press
ISBN 13 : 1000763463
Total Pages : 461 pages
Book Rating : 4.0/5 (7 download)
Download or read book Statistical Inference via Data Science: A ModernDive into R and the Tidyverse written by Chester Ismay and published by CRC Press. This book was released on 2019-12-23 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Inference via Data Science: A ModernDive into R and the Tidyverse provides a pathway for learning about statistical inference using data science tools widely used in industry, academia, and government. It introduces the tidyverse suite of R packages, including the ggplot2 package for data visualization, and the dplyr package for data wrangling. After equipping readers with just enough of these data science tools to perform effective exploratory data analyses, the book covers traditional introductory statistics topics like confidence intervals, hypothesis testing, and multiple regression modeling, while focusing on visualization throughout. Features: ● Assumes minimal prerequisites, notably, no prior calculus nor coding experience ● Motivates theory using real-world data, including all domestic flights leaving New York City in 2013, the Gapminder project, and the data journalism website, FiveThirtyEight.com ● Centers on simulation-based approaches to statistical inference rather than mathematical formulas ● Uses the infer package for "tidy" and transparent statistical inference to construct confidence intervals and conduct hypothesis tests via the bootstrap and permutation methods ● Provides all code and output embedded directly in the text; also available in the online version at moderndive.com This book is intended for individuals who would like to simultaneously start developing their data science toolbox and start learning about the inferential and modeling tools used in much of modern-day research. The book can be used in methods and data science courses and first courses in statistics, at both the undergraduate and graduate levels.
Author :
Publisher : Academic Press
ISBN 13 : 0123973163
Total Pages : 2668 pages
Book Rating : 4.1/5 (239 download)
Download or read book Brain Mapping written by and published by Academic Press. This book was released on 2015-02-14 with total page 2668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Mapping: A Comprehensive Reference, Three Volume Set offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed
Author : Ernst Wit
Publisher : John Wiley & Sons
ISBN 13 : 0470011076
Total Pages : 278 pages
Book Rating : 4.4/5 (7 download)
Download or read book Statistics for Microarrays written by Ernst Wit and published by John Wiley & Sons. This book was released on 2004-11-19 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in microarrays has increased considerably in the last ten years. This increase in the use of microarray technology has led to the need for good standards of microarray experimental notation, data representation, and the introduction of standard experimental controls, as well as standard data normalization and analysis techniques. Statistics for Microarrays: Design, Analysis and Inference is the first book that presents a coherent and systematic overview of statistical methods in all stages in the process of analysing microarray data – from getting good data to obtaining meaningful results. Provides an overview of statistics for microarrays, including experimental design, data preparation, image analysis, normalization, quality control, and statistical inference. Features many examples throughout using real data from microarray experiments. Computational techniques are integrated into the text. Takes a very practical approach, suitable for statistically-minded biologists. Supported by a Website featuring colour images, software, and data sets. Primarily aimed at statistically-minded biologists, bioinformaticians, biostatisticians, and computer scientists working with microarray data, the book is also suitable for postgraduate students of bioinformatics.
Author : Carlos M. Fonseca
Publisher : Springer Science & Business Media
ISBN 13 : 3540018697
Total Pages : 825 pages
Book Rating : 4.5/5 (4 download)
Download or read book Evolutionary Multi-Criterion Optimization written by Carlos M. Fonseca and published by Springer Science & Business Media. This book was released on 2003-04-07 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Second International Conference on Evolutionary Multi-Criterion Optimization, EMO 2003, held in Faro, Portugal, in April 2003. The 56 revised full papers presented were carefully reviewed and selected from a total of 100 submissions. The papers are organized in topical sections on objective handling and problem decomposition, algorithm improvements, online adaptation, problem construction, performance analysis and comparison, alternative methods, implementation, and applications.
Author : Alan D. Chave
Publisher : Cambridge University Press
ISBN 13 : 1107096006
Total Pages : 467 pages
Book Rating : 4.1/5 (7 download)
Download or read book Computational Statistics in the Earth Sciences written by Alan D. Chave and published by Cambridge University Press. This book was released on 2017-10-19 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines theoretical underpinnings of statistics with practical analysis of Earth sciences data using MATLAB. Supplementary resources are available online.
Author : Dr T.K.V. Iyengar & Dr B. Krishna Gandhi & S. Ranganadham &
Dr M.V.S.S.N. Prasad
Publisher : S. Chand Publishing
ISBN 13 : 9352837487
Total Pages : pages
Book Rating : 4.3/5 (528 download)
Download or read book Probability and Statistics & Complex Variables written by Dr T.K.V. Iyengar & Dr B. Krishna Gandhi & S. Ranganadham & Dr M.V.S.S.N. Prasad and published by S. Chand Publishing. This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Probability and Statistics & Complex Variables
