Multimodal Mri Investigation Of Eye And Visual Brain

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Multimodal MRI Investigation of Eye and Visual Brain

Author : Chin-Chak Ho
Publisher : Open Dissertation Press
ISBN 13 : 9781361042250
Total Pages : 258 pages
Book Rating : 4.0/5 (422 download)

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Book Synopsis Multimodal MRI Investigation of Eye and Visual Brain by : Chin-Chak Ho

Download or read book Multimodal MRI Investigation of Eye and Visual Brain written by Chin-Chak Ho and published by Open Dissertation Press. This book was released on 2017-01-26 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Multimodal MRI Investigation of Eye and Visual Brain" by Chin-chak, Ho, 何阡澤, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Although the eyes are physically isolated from the visual brain, the physiology and integrity of the eye are central to several eye diseases and neurodegeneration in the visual brain. MRI provides non-invasive, longitudinal and multi-parametric assessments of the visual system without depth limitation. The objective of this doctoral work is to develop and apply multimodal MRI for the assessment of aqueous humor dynamics, ocular fibrous tissue and visual pathway integrity in the visual system. The functional response in neural systems were further explored with BOLD and diffusion fMRI. Firstly, dynamic Gd-MRI was applied to visualize and assess aqueous humor dynamics upon sustained intraocular pressure elevation and pharmacological interventions. The results reflect the reduced gadolinium clearance upon microbead occlusion and respective drug actions after ocular hypotensive drug treatment. Abnormal gadolinium leakage into the vitreous was found in compromised aqueous-vitreous or blood-ocular barrier integrity. Gd-MRI allows spatiotemporal and quantitative evaluation of altered aqueous humor dynamics and ocular tissue permeability. Secondly, MAMRI was employed to reveal the structural details of the corneoscleral shell and their changes upon intraocular pressure elevation. At magic angle, high-resolution MRI revealed distinct scleral and corneal lamellar fibers, and collagen fiber crimps. Loaded sclera and cornea possessed significantly higher T2 and T2* than unloaded tissues at magic angle, suggestive of the changes in collagen fiber crimp and alignment. MAMRI can detect ocular fibrous microstructures without contrast agents, and can reveal their MR tissue property changes with IOP loading. Thirdly, multimodal MRI was utilized to investigate the effects of biomechanical or biochemical modulation on the sclera and cornea tissues. T2 in corneoscleral shell increased non-linearly with IOP loading and remained longer than unloaded tissues after being unpressurized. Biomechanical loading increased fractional anisotropy in the corneoscleral shell, while increasing glyceraldehyde and chondroitinase-ABC concentrations decreased diffusivities and increased magnetization transfer in cornea. Glyceraldehyde also increased magnetization transfer in sclera. The changes in MRI contrast mechanisms upon various modulation of the eye provide insight to the pathophysiological mechanisms in the corneoscleral shell and the efficacy of corneoscleral treatments. Fourthly, the effects of excitotoxic retinal injury on the retinal thickness, microstructual integrity and anterograde transport was evaluated in vivo by DTI, MEMRI and OCT. Directional diffusivities in the visual pathway and their correlations with retinal thickness suggested anterograde axonal degeneration and delayed demyelination along the visual pathway. The splenium of corpus callosum was reorganized at 4 weeks post injury. Furthermore, the NMDA-injured visual pathway showed reduced anterograde manganese transport. These results characterized the spatiotemporal changes in white matter integrity, the eye-brain relationships and structural-physiological relationships in the visual system. Lastly, BOLD and diffusion fMRI were used to explore the functional responses of neural systems. The efficacy of using unisensory stimuli to elicit cross-modal activation was examined by BOLD fMRI improving the understanding to cortical cross-modal activity and its influence

Multimodal MRI Investigation of Eye and Visual Brain

Author : Chin-Chak Ho
Publisher :
ISBN 13 : 9781361042274
Total Pages : pages
Book Rating : 4.0/5 (422 download)

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Book Synopsis Multimodal MRI Investigation of Eye and Visual Brain by : Chin-Chak Ho

Download or read book Multimodal MRI Investigation of Eye and Visual Brain written by Chin-Chak Ho and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Multimodal MRI Investigation of Eye and Visual Brain" by Chin-chak, Ho, 何阡澤, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Although the eyes are physically isolated from the visual brain, the physiology and integrity of the eye are central to several eye diseases and neurodegeneration in the visual brain. MRI provides non-invasive, longitudinal and multi-parametric assessments of the visual system without depth limitation. The objective of this doctoral work is to develop and apply multimodal MRI for the assessment of aqueous humor dynamics, ocular fibrous tissue and visual pathway integrity in the visual system. The functional response in neural systems were further explored with BOLD and diffusion fMRI. Firstly, dynamic Gd-MRI was applied to visualize and assess aqueous humor dynamics upon sustained intraocular pressure elevation and pharmacological interventions. The results reflect the reduced gadolinium clearance upon microbead occlusion and respective drug actions after ocular hypotensive drug treatment. Abnormal gadolinium leakage into the vitreous was found in compromised aqueous-vitreous or blood-ocular barrier integrity. Gd-MRI allows spatiotemporal and quantitative evaluation of altered aqueous humor dynamics and ocular tissue permeability. Secondly, MAMRI was employed to reveal the structural details of the corneoscleral shell and their changes upon intraocular pressure elevation. At magic angle, high-resolution MRI revealed distinct scleral and corneal lamellar fibers, and collagen fiber crimps. Loaded sclera and cornea possessed significantly higher T2 and T2* than unloaded tissues at magic angle, suggestive of the changes in collagen fiber crimp and alignment. MAMRI can detect ocular fibrous microstructures without contrast agents, and can reveal their MR tissue property changes with IOP loading. Thirdly, multimodal MRI was utilized to investigate the effects of biomechanical or biochemical modulation on the sclera and cornea tissues. T2 in corneoscleral shell increased non-linearly with IOP loading and remained longer than unloaded tissues after being unpressurized. Biomechanical loading increased fractional anisotropy in the corneoscleral shell, while increasing glyceraldehyde and chondroitinase-ABC concentrations decreased diffusivities and increased magnetization transfer in cornea. Glyceraldehyde also increased magnetization transfer in sclera. The changes in MRI contrast mechanisms upon various modulation of the eye provide insight to the pathophysiological mechanisms in the corneoscleral shell and the efficacy of corneoscleral treatments. Fourthly, the effects of excitotoxic retinal injury on the retinal thickness, microstructual integrity and anterograde transport was evaluated in vivo by DTI, MEMRI and OCT. Directional diffusivities in the visual pathway and their correlations with retinal thickness suggested anterograde axonal degeneration and delayed demyelination along the visual pathway. The splenium of corpus callosum was reorganized at 4 weeks post injury. Furthermore, the NMDA-injured visual pathway showed reduced anterograde manganese transport. These results characterized the spatiotemporal changes in white matter integrity, the eye-brain relationships and structural-physiological relationships in the visual system. Lastly, BOLD and diffusion fMRI were used to explore the functional responses of neural systems. The efficacy of using unisensory stimuli to elicit cross-modal activation was examined by BOLD fMRI improving the understanding to cortical cross-modal activity and its influence

Multimodal magnetic resonance imaging methods to explore the visual pathway and brain network changes in blindness disease

Author : Yan Tong
Publisher : Frontiers Media SA
ISBN 13 : 2832516041
Total Pages : 153 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Multimodal magnetic resonance imaging methods to explore the visual pathway and brain network changes in blindness disease by : Yan Tong

Download or read book Multimodal magnetic resonance imaging methods to explore the visual pathway and brain network changes in blindness disease written by Yan Tong and published by Frontiers Media SA. This book was released on 2023-03-09 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Probing Brain-Behavior Relationship with Multimodal Imaging: Methods and Clinical Applications

Author : Bin Jing
Publisher : Frontiers Media SA
ISBN 13 : 2832547591
Total Pages : 197 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Probing Brain-Behavior Relationship with Multimodal Imaging: Methods and Clinical Applications by : Bin Jing

Download or read book Probing Brain-Behavior Relationship with Multimodal Imaging: Methods and Clinical Applications written by Bin Jing and published by Frontiers Media SA. This book was released on 2024-04-10 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays, exploring the brain-behavior relationship via MRI, EEG, fNIRS, and MEG has become a research hotspot further accelerated by the emergence of large-sample open-source datasets, such as UK Biobank, Human Connectome Project, the Adolescent Brain Cognitive Development, the National Institute of Mental Health (NIMH) Intramural Healthy Volunteer Dataset, the TUH EEG CORPUS, and many other multimodal datasets. Many prior studies have conducted various prediction tasks in different populations (from infants to adults; from healthy subjects to patients) with miscellaneous imaging modalities, however, to construct a precise, generalizable, and reproducible brain-behavior relationship is still facing many challenges, for example, individual variability, multi-site heterogeneity, imaging result interpretability, model generalization, low prediction performance, and lack of clinical applications

Multimodal Brain Image Analysis

Author : Li Shen
Publisher : Springer
ISBN 13 : 3319021265
Total Pages : 268 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Multimodal Brain Image Analysis by : Li Shen

Download or read book Multimodal Brain Image Analysis written by Li Shen and published by Springer. This book was released on 2013-08-15 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the Third International Workshop on Multimodal Brain Image Analysis, MBIA 2013, held in Nagoya, Japan, on September 22, 2013 in conjunction with the 16th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI. The 24 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers are organized in topical sections on analysis, methodologies, algorithms, software systems, validation approaches, benchmark datasets, neuroscience and clinical applications.

fMRI: From Nuclear Spins to Brain Functions

Author : Kamil Uludag
Publisher : Springer
ISBN 13 : 1489975918
Total Pages : 926 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis fMRI: From Nuclear Spins to Brain Functions by : Kamil Uludag

Download or read book fMRI: From Nuclear Spins to Brain Functions written by Kamil Uludag and published by Springer. This book was released on 2015-09-16 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.

Application of Multimodal Imaging Combined with Artificial Intelligence in Eye Diseases

Author : Xin Huang
Publisher : Frontiers Media SA
ISBN 13 : 2832536107
Total Pages : 202 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Application of Multimodal Imaging Combined with Artificial Intelligence in Eye Diseases by : Xin Huang

Download or read book Application of Multimodal Imaging Combined with Artificial Intelligence in Eye Diseases written by Xin Huang and published by Frontiers Media SA. This book was released on 2023-10-18 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Subacute Spongiform Encephalopathy (Creutzfeldt-Jakob Disease)

Author : Colin L. Masters
Publisher :
ISBN 13 :
Total Pages : 16 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Subacute Spongiform Encephalopathy (Creutzfeldt-Jakob Disease) by : Colin L. Masters

Download or read book Subacute Spongiform Encephalopathy (Creutzfeldt-Jakob Disease) written by Colin L. Masters and published by . This book was released on 1979 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

MR Spectroscopy of Pediatric Brain Disorders

Author : Stefan Blüml
Publisher : Springer Science & Business Media
ISBN 13 : 1441958649
Total Pages : 405 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis MR Spectroscopy of Pediatric Brain Disorders by : Stefan Blüml

Download or read book MR Spectroscopy of Pediatric Brain Disorders written by Stefan Blüml and published by Springer Science & Business Media. This book was released on 2012-12-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.

Adler's Physiology of the Eye

Author : Leonard A Levin
Publisher : Elsevier Health Sciences
ISBN 13 : 0323057144
Total Pages : 810 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Adler's Physiology of the Eye by : Leonard A Levin

Download or read book Adler's Physiology of the Eye written by Leonard A Levin and published by Elsevier Health Sciences. This book was released on 2011-04-04 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F. E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts. You can also access the complete contents online at www.expertconsult.com. Deepen your grasp of the physiological principles that underlie visual acuity, color vision, ocular circulation, the extraocular muscle, and much more. Improve your understanding of physiology by referring to this totally updated volume--organized by function, rather than anatomy--and make a stronger connection between physiological principles and clinical practice. Better visualize information with a new, revamped format that includes 1,000 illustrations presented in full-color to better clarify complex concepts and functions. Access the most recent molecular, genetic, and biochemical discoveries affecting eye function, and gain fresh perspectives from a new, international editorial team. Search the entire contents online and download all the illustrations at www.expertconsult.com.

The Neurology of Eye Movements

Author : R. John Leigh
Publisher : Oxford University Press, USA
ISBN 13 : 0199969280
Total Pages : 1137 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Neurology of Eye Movements by : R. John Leigh

Download or read book The Neurology of Eye Movements written by R. John Leigh and published by Oxford University Press, USA. This book was released on 2015 with total page 1137 pages. Available in PDF, EPUB and Kindle. Book excerpt: "lt is a tremendous achievement to have provided this highly comprehensive but readable text, which informs such a large group of researchers and clinicians." Christopher Kennard, PhD, FRCP, FMedSci, Professor of Clinical Neurology, Head, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom. "A monograph written with deep knowledge, understanding, wisdom, clarity, intelligibility - the superlatives could go on and on... A remarkable achievement and a great gift to all of us from the two modern giants of eye movement disorders." Michael Halmagyi, MD, Eye and Ear Research Unit, Neurology Department, Royal Prince Alfred Hospital, The University of Sydney, Australia. "The fifth edition of The Neurology of Eye Movements is a must for all neurologists and neuroscientists interested in how the human vestibular and oculomotor systems adapt to movement in space and to optimally viewing the world and its contents." Louis R. Caplan, MD, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Brain Mapping

Author :
Publisher : Academic Press
ISBN 13 : 0123973163
Total Pages : 2668 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Brain Mapping by :

Download or read book Brain Mapping written by and published by Academic Press. This book was released on 2015-02-14 with total page 2668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Mapping: A Comprehensive Reference, Three Volume Set offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed

Eye Movement Research

Author : Christoph Klein
Publisher : Springer Nature
ISBN 13 : 303020085X
Total Pages : 1017 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Eye Movement Research by : Christoph Klein

Download or read book Eye Movement Research written by Christoph Klein and published by Springer Nature. This book was released on 2019-10-16 with total page 1017 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume presents fundamentals as well as applications of oculomotor methods in industrial and clinical settings. The topical spectrum covers 1.) basics and background material, 2.) methods such as recording techniques, markov models, Lévy flights, pupillometry and many more, as well as 3.) a broad range of applications in clinical and industrial settings. The target audience primarily comprises research experts and practitioners, but the book may also be beneficial for graduate students.

Vision and the Brain

Author : Amanda Hall Lueck
Publisher : AFB Press
ISBN 13 : 9780891286394
Total Pages : 720 pages
Book Rating : 4.2/5 (863 download)

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Book Synopsis Vision and the Brain by : Amanda Hall Lueck

Download or read book Vision and the Brain written by Amanda Hall Lueck and published by AFB Press. This book was released on 2015-04 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral visual impairment (also known as cortical visual impairment, or CVI) has become the most common cause of visual impairment in children in the United States and the developed world. Vision and the Brain is a unique and comprehensive sourcebook geared especially to professionals in the field of visual impairment, educators, and families who need to know more about the causes and types of CVI and the best practices for working with affected children. Expert contributors from many countries represent education, occupational therapy, orientation and mobility, ophthalmology, optometry, neuropsychology, psychology, and vision science, and include parents of children with CVI. The book provides an in-depth guide to current knowledge about brain-related vision loss in an accessible form to enable readers to recognize, understand, and assess the behavioral manifestations of damage to the visual brain and develop effective interventions based on identification of the spectrum of individual needs. Chapters are designed to help those working with children with CVI ascertain the nature and degree of visual impairment in each child, so that they can "see" and appreciate the world through the child's eyes and ensure that every child is served appropriately.

Imaging of Orbital and Visual Pathway Pathology

Author : Wibke S. Müller-Forell
Publisher : Springer Science & Business Media
ISBN 13 : 354027989X
Total Pages : 454 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Imaging of Orbital and Visual Pathway Pathology by : Wibke S. Müller-Forell

Download or read book Imaging of Orbital and Visual Pathway Pathology written by Wibke S. Müller-Forell and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deals with imaging of pathology of the visual system. This book is divided into two parts, general and special. In the general part, important basics of modern imaging methods are discussed. The knowledge on the indication, technique, and results of functional MR imaging is also presented.

OCT and Imaging in Central Nervous System Diseases

Author :
Publisher :
ISBN 13 : 9783030262709
Total Pages : 560 pages
Book Rating : 4.2/5 (627 download)

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Book Synopsis OCT and Imaging in Central Nervous System Diseases by :

Download or read book OCT and Imaging in Central Nervous System Diseases written by and published by . This book was released on 2020 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury. Covering disorders like multiple sclerosis, Parkinson's disease, Alzheimer's disease, intracranial hypertension, Friedreich's ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models. Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the "window to the brain".

Principles of Behavioral and Cognitive Neurology

Author : M.-Marsel Mesulam
Publisher : Oxford University Press
ISBN 13 : 0195134753
Total Pages : 577 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Principles of Behavioral and Cognitive Neurology by : M.-Marsel Mesulam

Download or read book Principles of Behavioral and Cognitive Neurology written by M.-Marsel Mesulam and published by Oxford University Press. This book was released on 2000-01-27 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised new edition of a classic book provides a clinically inspired but scientifically guided approach to the biological foundations of human mental function in health and disease. It includes authoritative coverage of all the major areas related to behavioral neurology, neuropsychology, and neuropsychiatry. Each chapter, written by a world-renowned expert in the relevant area, provides an introductory background as well as an up-to-date review of the most recent developments. Clinical relevance is emphasized but is placed in the context of cognitive neuroscience, basic neuroscience, and functional imaging. Major cognitive domains such as frontal lobe function, attention and neglect, memory, language, prosody, complex visual processing, and object identification are reviewed in detail. A comprehensive chapter on behavioral neuroanatomy provides a background for brain-behavior interactions in the cerebral cortex, limbic system, basal ganglia, thalamus, and cerebullum. Chapters on temperolimbic epilepsy, major psychiatric syndromes, and dementia provide in-depth analyses of these neurobehavioral entities and their neurobiological coordinates. Changes for this second edition include the reflection throughout the book of the new and flourishing alliance of behavioral neurology, neuropsychology, and neuropsychiatry with cognitive science;major revision of all chapters; new authorship of those on language and memory; and the inclusion of entirely new chapters on psychiatric syndromes and the dementias. Both as a textbook and a reference work, the second edition of Principles of Behavioral and Cognitive Neurology represents an invaluable resource for behavioral neurologists, neuropsychologists, neuropsychiatrists, cognitive and basic neuroscientists, geriatricians, physiatrists, and their students and trainees.