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Author : 陳乃慈
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (875 download)
Download or read book Multifunctional Mesoporous Silica Nanocomposite Nanoparticles for Theranostic Applications written by 陳乃慈 and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yu Chen
Publisher : Springer
ISBN 13 : 3662486229
Total Pages : 100 pages
Book Rating : 4.6/5 (624 download)
Download or read book Design, Synthesis, Multifunctionalization and Biomedical Applications of Multifunctional Mesoporous Silica-Based Drug Delivery Nanosystems written by Yu Chen and published by Springer. This book was released on 2015-10-14 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis reports on essential advances in the design, synthesis and biomedical applications of multifunctional Mesoporous Silica Nanoparticles (MSNs). It provides several examples of multifunctional MSN-based drug delivery nanosystems and demonstrates successful synergistic cancer therapies combining MSNs and high-intensity focused ultrasound. The book will especially be of interest to researchers and graduate students in the fields of biomaterials, biology, chemistry, medicine and the life sciences who are working to develop new methods and technologies to combat cancer.
Author : Malay K. Das
Publisher : Academic Press
ISBN 13 : 0128217006
Total Pages : 428 pages
Book Rating : 4.1/5 (282 download)
Download or read book Multifunctional Theranostic Nanomedicines in Cancer written by Malay K. Das and published by Academic Press. This book was released on 2021-03-16 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment
Author : Ruining Wang
Publisher :
ISBN 13 :
Total Pages : 226 pages
Book Rating : 4.:/5 (116 download)
Download or read book Multifunctional Mesoporous Silica Nanoparticles for Drug and Large Molecule Delivery written by Ruining Wang and published by . This book was released on 2020 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis involves synthesis, derivatization and biomedical applications of mesoporous silica nanoparticles (MSNs) based delivery systems. Chapter 1 introduces the background of MSNs including the advantages of MSNs, modification on MSNs for multifunctionality; formation mechanism, a typical synthesis condition for MCM-41 and following characterizaitons. In chapter 2 & 3, the synthesis and application of target moiety functionalized MSNs for gene therapy in vitro and in vivo are introduced. Chapters 4, & 5 introduce the relevant studies of utilizing MSN based delivery system for the treatment of infectious disease, from a pharmacokinetic study of moxifloxacin delivered by MSNs via different routes, to the enhanced efficacy of MSN based treatment by materials optimizations via inhalation administration route. Chapter 6 discusses the study of a general synthesis method for pore enlargement in various types of MSNs. In Chapter 7, the design and preparation of a thin film consist of ultra large pore-sized mesoporous silica spheres and polymer template macropores is illustrated. Overall, these chapters demonstrate the successful engineering of mesoporous silica nanoparticles and materials optimization and their enhanced performance in biological applications from in vivo tumor shrinkage by gene delivery to antibiotics delivery for enhanced bacterial killing efficacy in mouse model.
Author :
Publisher :
ISBN 13 :
Total Pages : 233 pages
Book Rating : 4.:/5 (911 download)
Download or read book Tailoring Properties of Multifunctional Mesoporous Silica Nanoparticles for Controlled Drug Delivery Applications written by and published by . This book was released on 2014 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Academic Press
ISBN 13 : 0128155213
Total Pages : 228 pages
Book Rating : 4.1/5 (281 download)
Download or read book Mesoporous Silica-based Nanomaterials and Biomedical Applications - Part A written by and published by Academic Press. This book was released on 2018-09-20 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Therapy and Diagnosis, Part A, Volume 43 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on Mesoporous silica nanoparticle synthesis, Periodic mesoporous organosilica, Nanovalves and other nanomachine-equipped nanoparticles and controlled release, Two-photon light control and photodynamic therapy, Biodegradable PMO nanoparticles, Cationic mesoporous silica and protein delivery, Drug loading, stimuli-responsive delivery and cancer treatment, Animal models and cancer therapy, siRNA delivery and TWIST shutdown for ovarian cancer treatment, and TBC (mesoporous silica nanoparticles and cancer therapy or biodistribution of MSN). Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series Updated release includes the latest information on Cancer Therapy and Diagnosis
Author : Malay K. Das
Publisher : Springer Nature
ISBN 13 : 9811562555
Total Pages : 634 pages
Book Rating : 4.8/5 (115 download)
Download or read book Nano Medicine and Nano Safety written by Malay K. Das and published by Springer Nature. This book was released on 2020-12-09 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.
Author : Wei Chen
Publisher :
ISBN 13 :
Total Pages : 263 pages
Book Rating : 4.:/5 (112 download)
Download or read book Design and Synthesis of Multifunctional Mesoporous Silica Nanoparticles for Drug Delivery and Bioimaging Applications written by Wei Chen and published by . This book was released on 2019 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional mesoporous silica nanoparticles (MSNs) have aroused much attention during the past decades for drug delivery and bioimaging applications because of their intrinsic properties including extremely high surface area, large pore volume, tunable pore diameter, easy surface modification, and high biocompatibility. Even though MSNs have these preeminent properties, rendering this unique nanostructure a promising nanocarrier for biomedical applications, several hurdles still challenge the fields of drug delivery and bioimaging when using MSNs as the nanocarries: (i) high loading and high release amounts of water-insoluble drugs delivered to the site of diseases; (ii) precise control of the dosage of drugs delivered to the site of diseases using non-invasive external stimuli; and (iii) construction of MSNs-based shortwave infrared optical imaging contrast agents as an innovative tool for bioimaging and cancer diagnostics. Therefore, this dissertation primarily focuses on the development of innovative strategies that solve these unmet needs and that advance the research in the field of biomedical applications using MSNs as the nanocarriers. In this dissertation, first of all, we review the research work, which mainly focuses on the design and synthesis of multifunctional MSNs and nanomachines for biomedical applications in Accounts of Chemical Research. A wide variety of nanomachines responsive to the different stimuli (pH, redox, enzyme, heat, light, and/or magnetic field) are discussed in this Account. Additionally, we develop a facile strategy for MSNs delivery and release of the water-insoluble drug clofazimine (CFZ), which is used to treat multidrug-resistant tuberculosis. The strategy employs a companion molecule as a chaperone to improve both the loading of CFZ into the pores of MSNs and its subsequent release, thus enabling both high loading and high release of this water-insoluble drug by MSNs. In vitro treatment of macrophages infected with Mycobacterium tuberculosis with the optimized CFZ-loaded MSNs killed the bacteria in the cells in a dose-dependent manner. These studies demonstrate a highly efficient method for loading nanoparticles with water-insoluble drug molecules and the efficacy of the nanoparticles in delivering drugs into eukaryotic cells in aqueous media. Additionally, we used a noninvasive alternating magnetic field (AMF) to stimulate and control the dosage of drug release from MSNs. Noninvasive stimuli-responsive drug delivery using AMF in conjunction with superparamagnetic nanoparticles also offers the potential for the spatial and temporal control of drug release. In vitro studies showed that the death of pancreatic cancer cells treated by drug-loaded nanoparticles was controlled by different lengths of AMF exposure time due to different amounts of drug released from the carriers. Finally, to develop a new shortwave infrared (SWIR) optical imaging contrast agent which has a higher tissue penetration depth, we demonstrate that J-aggregates of near infrared (NIR) fluorophore IR-140 can be prepared inside hollow mesoporous silica nanoparticles (HMSNs) to result in nanomaterials that absorb and emit SWIR light. The use of J-aggregates stabilized in HMSNs as SWIR imaging agents has the potential to overcome the stability, toxicity, and brightness challenges of contrast agents for this compelling region of the electromagnetic spectrum. Collectively, in this dissertation, we explore and develop innovative strategies to load and deliver high amounts of water-insoluble drugs; control the dosage of anticancer drugs released from MSNs triggered by an AMF; and establish a new SWIR optical imaging contrast agent based on the superior carriers - MSNs.
Author :
Publisher : Elsevier
ISBN 13 : 0128139358
Total Pages : 292 pages
Book Rating : 4.1/5 (281 download)
Download or read book Nano-sized Multifunctional Materials written by and published by Elsevier. This book was released on 2018-11-20 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nano-sized Multifunctional Materials: Synthesis, Properties and Applications explores how materials can be down-scaled to nanometer-size in order to tailor and control properties. These advanced, low-dimensional materials, ranging from quantum dots and nanoparticles, to ultra-thin films develop multifunctional properties. As well as demonstrating how down-scaling to nano-size can make materials multifunctional, chapters also show how this technology can be applied in electronics, medicine, energy and in the environment. This fresh approach in materials research will provide a valuable resource for materials scientists, materials engineers, chemists, physicists and bioengineers who want to learn more on the special properties of nano-sized materials. Outlines the major synthesis chemical process and problems of advanced nanomaterials Shows how multifunctional nanomaterials can be practically used in biomedical area, nanomedicine, and in the treatment of pollutants Demonstrates how the properties of a variety of materials can be engineered by downscaling them to nano size
Author : María Vallet-Regí
Publisher : CRC Press
ISBN 13 : 1439883076
Total Pages : 245 pages
Book Rating : 4.4/5 (398 download)
Download or read book Biomedical Applications of Mesoporous Ceramics written by María Vallet-Regí and published by CRC Press. This book was released on 2012-11-28 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developments in mesoporous ceramics in drug delivery, nanomedicine, and bone tissue regeneration have opened promising developments in biomedical research, many applicable in the clinic in the near future. Due to the ability to fine-tune the physicochemical properties of these materials, the field has experienced an impressive burst in the number of publications. As controlled drug delivery systems are one of the most promising applications for human health care, it is now necessary to set the milestones of this technology, from the very basic to the most advanced. Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering is a comprehensive overview of silica-based mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The book provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity. Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuli-responsive materials and bone tissue engineering, detailing the research and development of these biomedical applications.
Author : Gianni Ciofani
Publisher : Frontiers Media SA
ISBN 13 : 2889636216
Total Pages : 187 pages
Book Rating : 4.8/5 (896 download)
Download or read book Advanced Theranostic Nanomedicine in Oncology written by Gianni Ciofani and published by Frontiers Media SA. This book was released on 2020-03-18 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464990468
Total Pages : 14170 pages
Book Rating : 4.4/5 (649 download)
Download or read book Advances in Nanotechnology Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 14170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Nanotechnology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Nanotechnology. The editors have built Advances in Nanotechnology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Nanotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Nanotechnology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Valentina Cauda
Publisher : MDPI
ISBN 13 : 3039439391
Total Pages : 204 pages
Book Rating : 4.0/5 (394 download)
Download or read book Mesoporous Materials for Drug Delivery and Theranostics written by Valentina Cauda and published by MDPI. This book was released on 2020-12-17 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesoporous materials are capturing great interest thanks to their exceptional surface area, uniform and tunable pore size, ease surface functionalization, thus enabling broad series of intervention in the field of nanomedicine. Since many years, these aspects foster a deep investigation on mesoporous nanoparticles, to design and fabricate biocompatible, smart and stimuli-responsive nanotools for controlled drug- or gene-delivery, theranostics applications, in particular for cancer therapy, and tissue engineering. This Book is thus dedicated to the most recent advances in the field, collecting research papers and reviews. It spans from the synthesis and characterization of the mesoporous material, especially those made of silica, silicon and bioactive glasses, to their functionalization with smart gate-keepers, reporter molecules or targeting ligands, up to their in-vitro applications in the nanomedicine field.
Author : Mingqian Tan
Publisher : World Scientific
ISBN 13 : 981463543X
Total Pages : 430 pages
Book Rating : 4.8/5 (146 download)
Download or read book Nanomaterials For Tumor Targeting Theranostics: A Proactive Clinical Perspective written by Mingqian Tan and published by World Scientific. This book was released on 2016-02-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials offer great potential for effective tumor diagnosis and therapy combing diagnostic agents and therapeutic drugs into one platform. In this book, the most recent progress of main nanomaterials and their applications in tumor targeting theranostics is presented. It summarizes the recent advances of current principal nanomaterials in tumor theranostics, including magnetic nanomaterials, quantum dots, mesoporous silica nanoparticles, gold nanomaterials, polymeric nanosystem, carbon nanomaterials, lipopolyplex nanoparticles, microbubbles, upconversion nanomaterials and dendrimers. It will enable readers to get a more realistic understanding of both the advantages and limitations of nanomaterials for potential tumor targeting theranosis. The publication of this book will accelerate the spread of ideas that are currently trickling through the scientific literature. Also a greater understanding of the potential and challenge of nanomaterials for tumor targeting theranostics is highly anticipated for practical clinical use.
Author : Weibo Cai
Publisher : CRC Press
ISBN 13 : 1315353784
Total Pages : 649 pages
Book Rating : 4.3/5 (153 download)
Download or read book Hybrid Nanomaterials written by Weibo Cai and published by CRC Press. This book was released on 2017-05-25 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, an unprecedented expansion in the field of nanomedicine has resulted in the development of new nanomaterials for diagnosis and therapy of various diseases such as cancer. This book covers the design, synthesis and applications of various functionally-hybridized nanomaterials for biomedical applications. It includes strategies for design and synthesis of hybrid nanomaterials, surface engineering of various nanoparticle-based hybrid nanosystems for cancer imaging and therapy, toxicity aspects of nanomaterials and the challenges in translation research of hybrid nanomaterials.
Author : Juan Vivero-Escoto
Publisher :
ISBN 13 : 9781613244524
Total Pages : 0 pages
Book Rating : 4.2/5 (445 download)
Download or read book Silica Nanoparticles written by Juan Vivero-Escoto and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, the authors present topical research in the study of the preparation, properties and use of silica nanoparticles. Topics discussed include the reactivity of inorganic radicals and excited triplet states in colloidal silica suspensions; multifunctional mesoporous silica nanoparticles for controlled drug delivery, multimodal imaging and simultaneous imaging and drug delivery; monodisperse luminescent silica nanoparticles and their application to DNA microarray technology.
Author : Barkat, Md. Abul
Publisher : IGI Global
ISBN 13 : 1522547827
Total Pages : 624 pages
Book Rating : 4.5/5 (225 download)
Download or read book Multifunctional Nanocarriers for Contemporary Healthcare Applications written by Barkat, Md. Abul and published by IGI Global. This book was released on 2018-01-12 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in technology permeates every aspect of life, including the healthcare system. Nanotechnology based systems have gained popularity based upon their promise, size, and other characteristics. Multifunctional Nanocarriers for Contemporary Healthcare Applications is a critical academic publication that explores advancements in nanostructured systems, applications of these systems in healthcare, and biomedical applications of these systems. Featuring coverage on a wide range of topics, such as hydrogels, controlled drug delivery systems, and nanomedicine, this book is geared toward researchers, students, and academicians seeking current research on advancements and applications of nanostructured systems in the healthcare industry.
