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Author : Robert William Baldwin
Publisher :
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibodies for Cancer Detection and Therapy written by Robert William Baldwin and published by . This book was released on 1985 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Brian A. Baldo
Publisher : Springer
ISBN 13 : 3319304720
Total Pages : 623 pages
Book Rating : 4.3/5 (193 download)
Download or read book Safety of Biologics Therapy written by Brian A. Baldo and published by Springer. This book was released on 2016-08-12 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.
Author : Ralph A. Reisfeld
Publisher :
ISBN 13 :
Total Pages : 640 pages
Book Rating : 4.:/5 (45 download)
Download or read book Monoclonal Antibodies and Cancer Therapy written by Ralph A. Reisfeld and published by . This book was released on 1985 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Suresh C. Srivastava
Publisher : Springer Science & Business Media
ISBN 13 : 1468455389
Total Pages : 851 pages
Book Rating : 4.4/5 (684 download)
Download or read book Radiolabeled Monoclonal Antibodies for Imaging and Therapy written by Suresh C. Srivastava and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of hybridoma technology leading to the successful produc tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations. These highly specific reagents have essentially replaced the polysera of the earlier days. The successful demonstration of the many wide ranging capabilities of the monoclonal antibody technique has already begun to exert an enormous impact on diverse areas of research in basic science and medicine. In particular, the potential of monoclonal antibodies to serve as carriers for selective targeting of radionuclides to tumors for diagnosis or therapy, has stimulated an intense surge of research interest and even revived hopes of realizing Ehrlich's concept of the "magic bullet". Indeed, the technology appears to be on the threshold of a revolution in diagnosing and treating malignant disease. Much work remains to be done, however, and even though the progress has been impressive, results to date have shown only moderate success. There is no question that the limited success we have achieved thus far is merely a prelude to the many more exciting developments yet to come.
Author : Kenneth A. Foon
Publisher : Springer Science & Business Media
ISBN 13 : 1461326273
Total Pages : 171 pages
Book Rating : 4.4/5 (613 download)
Download or read book Monoclonal Antibody Therapy of Human Cancer written by Kenneth A. Foon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: KENNETH A. FOON and ALTON C. MORGAN, JR. Passive immunotherapy using heteroantisera for the treatment of cancer in animals and humans has been studied for over 50 years. Attempts have been made to treat animal tumors with sera from immunized syngeneic, allogeneic, or xenogeneic animals. A number of studies of passive immunotherapy using heterologous antisera in humans have also been performed. These studies have generally been attempted in patients with large tumor burdens, and as would be expected, results have been transient at best. A wide variety of solid tumors as well as leukemias and lym phomas have been treated with antisera raised in sheep, horses, rabbits, and goats. Problems such as anaphylaxis, serum sick ness, and severe cytopenias have been encountered with these antisera. There are a number of potential mechanisms by which unconju gated antibodies might be cytotoxic to tumor cells. Antibodies bound to the cell surface membrane of tumor cells may lead to cell lysis by complement-dependent or antibody-dependent cellu lar cytotoxicity. Circulating tumor cells bound by antibody may be more susceptible to phagocytosis by the reticuloendothelial system. Antibody bound to the cell surface membrane of tumor cells may enhance immunogenicity of the tumor cell leading to activation of the host's immune system.
Author :
Publisher :
ISBN 13 :
Total Pages : 196 pages
Book Rating : 4.:/5 (319 download)
Download or read book International Symposium on Labeled and Unlabeled Antibody in Cancer Diagnosis and Therapy written by and published by . This book was released on 1987 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : H. H. Sedlacek
Publisher :
ISBN 13 :
Total Pages : 196 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibodies in Tumor Therapy written by H. H. Sedlacek and published by . This book was released on 1988 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Carl-Wilhelm Vogel
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 330 pages
Book Rating : 4.3/5 (91 download)
Download or read book Immunoconjugates written by Carl-Wilhelm Vogel and published by Oxford University Press, USA. This book was released on 1987 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoconjugate research aims to develop improved methods of cancer detection and more effective, efficient drugs to combat cancer. This book contains contributions from virtually all established research groups in the immunotoxin field and offers a comprehensive discussion of current and potential applications of immunoconjugates, covering all pertinent topics from chemical synthesis to clinical trial.
Download or read book Monoclonal antibodies in cancer therapy written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : GRIN Verlag
ISBN 13 : 3346813304
Total Pages : 33 pages
Book Rating : 4.3/5 (468 download)
Download or read book The role of antibodies in cancer treatment and diagnosis written by and published by GRIN Verlag. This book was released on 2023-02-15 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bachelor Thesis from the year 2022 in the subject Medicine - Human Genetics, grade: 2,0, , language: English, abstract: Monoclonal antibodies in cancer therapy, future outlook, present situation. The topic is approached via a literature review article to give the reader a good overview. The report is based on online database research via PubMed, Cochrane Library, Google Scholar, and ScienceDirect. The purpose of this article is to evaluate the role of antibodies in immunology and their possibilities and limitations in cancer diagnosis and treatment. The references were chosen with regard to their relevance and actuality regarding the discussed topic. Mesh search was used, and further information regarding research tactics is provided in the methodology. In this article, we did shine a light on different aspects of monoclonal antibody usage and the general principles of this novel therapeutic approach. The general mechanism, as well as pharmaceutical preparations, are discussed. This approach lets this work present solid basics of the theoretical and practical considerations, pathways, as well as benefits and risks of monoclonal therapeutics. More research in the future could provide even more promising results and provide ways to lower mortality from cancer and, eventually, other diseases.
Author : Jack A. Roth
Publisher : Blackwell/Futura
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibodies in Cancer written by Jack A. Roth and published by Blackwell/Futura. This book was released on 1986 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David M. Goldenberg
Publisher : Springer Science & Business Media
ISBN 13 : 1461314976
Total Pages : 469 pages
Book Rating : 4.4/5 (613 download)
Download or read book Cancer Imaging with Radiolabeled Antibodies written by David M. Goldenberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Author :
Publisher :
ISBN 13 :
Total Pages : 268 pages
Book Rating : 4.3/5 (91 download)
Download or read book Symposium on Monoclonal Antibodies for Therapy, Prevention, and in Vivo Diagnosis of Human Disease written by and published by . This book was released on 1990 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jerome M. Vaeth
Publisher :
ISBN 13 :
Total Pages : 286 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Present and Future Role of Monoclonal Antibodies in the Management of Cancer written by Jerome M. Vaeth and published by . This book was released on 1990 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Henrik J. Ditzel
Publisher :
ISBN 13 : 9788716163691
Total Pages : 42 pages
Book Rating : 4.1/5 (636 download)
Download or read book Human Monoclonal Antibodies written by Henrik J. Ditzel and published by . This book was released on 1999 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309173051
Total Pages : 74 pages
Book Rating : 4.3/5 (91 download)
Download or read book Monoclonal Antibody Production written by National Research Council and published by National Academies Press. This book was released on 1999-05-06 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Anti-Vivisection Society (AAVS) petitioned the National Institutes of Health (NIH) on April 23, 1997, to prohibit the use of animals in the production of mAb. On September 18, 1997, NIH declined to prohibit the use of mice in mAb production, stating that "the ascites method of mAb production is scientifically appropriate for some research projects and cannot be replaced." On March 26, 1998, AAVS submitted a second petition, stating that "NIH failed to provide valid scientific reasons for not supporting a proposed ban." The office of the NIH director asked the National Research Council to conduct a study of methods of producing mAb. In response to that request, the Research Council appointed the Committee on Methods of Producing Monoclonal Antibodies, to act on behalf of the Institute for Laboratory Animal Research of the Commission on Life Sciences, to conduct the study. The 11 expert members of the committee had extensive experience in biomedical research, laboratory animal medicine, animal welfare, pain research, and patient advocacy (Appendix B). The committee was asked to determine whether there was a scientific necessity for the mouse ascites method; if so, whether the method caused pain or distress; and, if so, what could be done to minimize the pain or distress. The committee was also asked to comment on available in vitro methods; to suggest what acceptable scientific rationale, if any, there was for using the mouse ascites method; and to identify regulatory requirements for the continued use of the mouse ascites method. The committee held an open data-gathering meeting during which its members summarized data bearing on those questions. A 1-day workshop (Appendix A) was attended by 34 participants, 14 of whom made formal presentations. A second meeting was held to finalize the report. The present report was written on the basis of information in the literature and information presented at the meeting and the workshop.
Author : Ralph A. Reisfeld
Publisher :
ISBN 13 : 9780471847526
Total Pages : 632 pages
Book Rating : 4.8/5 (475 download)
Download or read book Monoclonal Antibodies and Cancer Therapy written by Ralph A. Reisfeld and published by . This book was released on 1985-12 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt:
