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Molecular Radiobiology
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Book Synopsis Molecular Radiation Biology by : Hermann Dertinger
Download or read book Molecular Radiation Biology written by Hermann Dertinger and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.
Book Synopsis The Molecular Theory of Radiation Biology by : K. H. Chadwick
Download or read book The Molecular Theory of Radiation Biology written by K. H. Chadwick and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: In late 1971 we were involved in a study of the interaction of radiation with matter and were trying to use measurements of radiation fluorescence in biological molecules to indicate how radiation affected living cells. It soon became apparent that we were working in the dark; the doses we used to get a significant signal were too large to be of interest for radiation biology and although the DNA molecule appeared to be the most likely target molecule we did not know which sort of events and which sort oflesions were the most important. We decided to alter our approach to see if we could find any consistent mathematical order in the radiobiological dose relationships. We found that cell survival curves could be very usefully described by a linear-quadratic dose relationship and very soon came to the somewhat premature but, as it turned out, most effective conclusion that the induction of DNA double strand breaks should be linear-quadratic. In deciding that the DNA double strand break was the crucial and all-important lesion we were able to associate the mathematical analysis with the biology of the cell and were able to relate known properties of the DNA molecule to known radiobiological effects. On the other hand, we were restricted and brought, from an abstract two-hit lesion which could have any property one wished, down to earth, to a defined moleccular structure of nanometer dimensions and well-known functions and properties.
Book Synopsis Radiobiology for the Radiologist by : Eric J. Hall
Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt: In print since 1972, this seventh edition of Radiobiology for the Radiologist is the most extensively revised to date. It consists of two sections, one for those studying or practicing diagnostic radiolo, nuclear medicine and radiation oncology; the other for those engaged in the study or clinical practice of radiation oncology--a new chapter, on radiologic terrorism, is specifically for those in the radiation sciences who would manage exposed individuals in the event of a terrorist event. The 17 chapters in Section I represent a general introduction to radiation biology and a complete, self-contained course especially for residents in diagnostic radiology and nuclear medicine that follows the Syllabus in Radiation Biology of the RSNA. The 11 chapters in Section II address more in-depth topics in radiation oncology, such as cancer biology, retreatment after radiotherapy, chemotherapeutic agents and hyperthermia. Now in full color, this lavishly illustrated new edition is replete with tables and figures that underscore essential concepts. Each chapter concludes with a "summary of pertinent conclusions" to facilitate quick review and help readers retain important information.
Book Synopsis Molecular Radiobiology by : N. B. Strazhevskaya
Download or read book Molecular Radiobiology written by N. B. Strazhevskaya and published by John Wiley & Sons. This book was released on 1975 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Physical and Chemical Mechanisms in Molecular Radiation Biology by : William A. Glass
Download or read book Physical and Chemical Mechanisms in Molecular Radiation Biology written by William A. Glass and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.
Book Synopsis Radiobiology for the Radiologist by : Eric J. Hall
Download or read book Radiobiology for the Radiologist written by Eric J. Hall and published by Lippincott Williams & Wilkins. This book was released on 2018-04-16 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Considered the “gold standard” in the field for over 45 years, Radiobiology for the Radiologist combines traditional and molecular radiation biology principles and appeals to students, residents, and veteran clinical practitioners. This edition continues the two-part format of previous editions and features brand-new chapters, thoroughly updated content, and hundreds of figures that provide a visual context to the information in each chapter.
Book Synopsis Molecular radiobiology by : N. B. Straževskaja
Download or read book Molecular radiobiology written by N. B. Straževskaja and published by . This book was released on 1975 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiobiology Textbook by : Sarah Baatout
Download or read book Radiobiology Textbook written by Sarah Baatout and published by Springer Nature. This book was released on 2023-09-23 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook focuses on the various aspects of radiobiology. The goal of radiobiological research is to better understand the effects of radiation exposure at the cellular and molecular levels in order to determine the impact on health. This book offers a unique perspective, by covering not only radiation biology but also radiation physics, radiation oncology, radiotherapy, radiochemistry, radiopharmacy, nuclear medicine, space radiation biology & physics, environmental and human radiation protection, nuclear emergency planning, molecular biology and bioinformatics, as well as the ethical, legal and social considerations related to radiobiology. This range of disciplines contributes to making radiobiology a broad and rather complex topic. This textbook is intended to provide a solid foundation to those interested in the basics and practice of radiobiological science. It is a learning resource, meeting the needs of students, scientists and medical staff with an interest in this rapidly evolving discipline, as well as a teaching tool, with accompanying teaching material to help educators.
Book Synopsis Introduction To Radiobiology by : Maurice Tubiana
Download or read book Introduction To Radiobiology written by Maurice Tubiana and published by CRC Press. This book was released on 2005-10-10 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers many aspects of radiation, radiotherapy and their effects. It includes a discussion of recent advances, such as the molecular basis of cellular effects and cell radiosensitivity, radiocarcinogenesis and how radiotherapy can affect normal and neoplastic tissues.
Author :Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation Publisher :National Academies Press ISBN 13 :0309133343 Total Pages :422 pages Book Rating :4.3/5 (91 download)
Book Synopsis Health Risks from Exposure to Low Levels of Ionizing Radiation by : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
Book Synopsis Biomolecular Action of Ionizing Radiation by : Shirley Lehnert
Download or read book Biomolecular Action of Ionizing Radiation written by Shirley Lehnert and published by CRC Press. This book was released on 2007-10-24 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Embracing the transformation of radiation sciences by the recent surge of developments in molecular biology, this progressive text offers an up-to-date analysis of in vitro and in vivo molecular responses in the body induced by ionizing radiation. With a unique emphasis on medical physics applications, Biomolecular Action of Ionizi
Book Synopsis Molecular Radio-Oncology by : Michael Baumann
Download or read book Molecular Radio-Oncology written by Michael Baumann and published by Springer. This book was released on 2016-06-18 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography. By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
Book Synopsis Computational Approaches in Molecular Radiation Biology by : Matesh N. Varma
Download or read book Computational Approaches in Molecular Radiation Biology written by Matesh N. Varma and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Office of Health and Environmental Research (OHER) has supported and continues to support development of computational approaches in biology and medicine. OHER's Radiological and Chemical Physics Program initiated development of computational approaches to determine the effects produced by radiation of different quality (such as high energy electrons, protons, helium and other heavy ions, etc. ) in a variety of materials of biological interest-such as water, polymers and DNA; these include molecular excitations and sub-excitations and the production of ionization and their spatial and temporal distribution. In the past several years, significant advances have been made in computational methods for this purpose. In particular, codes based on Monte Carlo techniques have ·been developed that provide a realistic description of track-structure produced by charged particles. In addition, the codes have become sufficiently sophisticated so that it is now possible to calculate the spatial and temporal distribution of energy deposition patterns in small volumes of subnanometer and nanometer dimensions. These dimensions or resolution levels are relevant for our understanding of mechanisms at the molecular level by which radiations affect biological systems. Since the Monte Carlo track structure codes for use in radiation chemistry and radiation biology are still in the developmental stage, a number of investigators have been exploring different strategies for improving these codes.
Book Synopsis Molecular Determinants of Radiation Response by : Theodore L. DeWeese
Download or read book Molecular Determinants of Radiation Response written by Theodore L. DeWeese and published by Springer Science & Business Media. This book was released on 2011-03-23 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Determinants of Radiation Response includes chapters by expert authors who detail the present understanding of key DNA damage response pathways and proteins. The chapters include comprehensive discussions on where and how specific alterations in function of these pathways and proteins result in substantive modifications of cellular response to DNA injury. Given the importance of therapies that induce DNA injury in the management of human disease, this book is timely and relevant for basic and translational researchers, as well as clinicians alike.
Book Synopsis Health Risks of Radon and Other Internally Deposited Alpha-Emitters by : National Research Council
Download or read book Health Risks of Radon and Other Internally Deposited Alpha-Emitters written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.
Book Synopsis Basic Clinical Radiobiology by : Michael C. Joiner
Download or read book Basic Clinical Radiobiology written by Michael C. Joiner and published by CRC Press. This book was released on 2018-08-28 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Builds on success and reputation of previous editions Draws on the considerable teaching experience of an international author team, most notably the US and European Editors The gold-standard European text for training, adopted by ESTRO as a course book, as a text for the Royal College of Radiologists' radiobiology exam and by courses in the US Highly illustrated with new, 2 colour illustrations Clear and concise style, appropriate for trainees and also practising radiation oncologists requiring a ready reference to the subject Includes new chapters on stem cells, tissue response and the meeting point of meeting point of radiotherapy, radiobiology and physics
Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
